Article ; Online: Role of simple inflammatory parameters in predicting the severity of coronary artery disease.
Revista da Associacao Medica Brasileira (1992)
2023 Volume 69, Issue 11, Page(s) e20230518
Abstract: Objective: In our study, we aimed to find simple, useful biomarkers in patients with non-ST elevation myocardial infarction to predict coronary artery severity.: Methods: Between May 2022 and December 2022, patients diagnosed with non-ST elevation ... ...
Abstract | Objective: In our study, we aimed to find simple, useful biomarkers in patients with non-ST elevation myocardial infarction to predict coronary artery severity. Methods: Between May 2022 and December 2022, patients diagnosed with non-ST elevation myocardial infarction according to the European cardiology guidelines were included in our study. The Synergy between PCI with Taxus and Cardiac Surgery score was calculated to determine the severity of coronary artery disease. These patients were classified into two groups according to Synergy between PCI with Taxus and Cardiac Surgery≥23 and Synergy between PCI with Taxus and Cardiac Surgery<23 scores. Biochemical markers such as platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio were studied in blood tests taken before coronary angiography in patients diagnosed with non-ST elevation myocardial infarction according to current guidelines. These two groups were compared in terms of the data obtained. Results: There were 281 patients in group 1 and 67 patients in group 2. There was no significant difference between the two groups in terms of demographic data such as age and gender. Platelet-to-lymphocyte ratio [group 1=125 (26-134) and group 2=156 (73-293); p=0.001] and neutrophil-to-lymphocyte ratio [group 1=2.71 (1.3-30.2) and group 2=3.2 (2.1-32.1); p=0.002] were higher in the group of patients with a Synergy between PCI with Taxus and Cardiac Surgery score of <23, while lymphocyte-to-monocyte ratio [group 1=3.6 (0.56-11) and group 2=3.4 (0.64-5.75); p=0.017] was lower in group 2. Conclusion: We observed that elevated platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios showed coronary artery severity. Multivessel disease and chronic total occlusion rates were observed to be higher in patients with high platelet-to-lymphocyte and neutrophil-to-lymphocyte ratios. |
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MeSH term(s) | Humans ; Coronary Artery Disease/surgery ; Percutaneous Coronary Intervention ; Risk Factors ; Coronary Angiography ; Non-ST Elevated Myocardial Infarction |
Language | English |
Publishing date | 2023-10-09 |
Publishing country | Brazil |
Document type | Journal Article |
ZDB-ID | 731969-1 |
ISSN | 1806-9282 ; 0104-4230 ; 0004-5241 ; 0102-843X |
ISSN (online) | 1806-9282 |
ISSN | 0104-4230 ; 0004-5241 ; 0102-843X |
DOI | 10.1590/1806-9282.20230518 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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