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  1. Article: Supraventricular Tachycardia Associated With Ondansetron.

    Samara, Evangelia / Karakosta, Agathi / Tseniklidis, Paraskevas / Tzimas, Petros

    Hospital pharmacy

    2023  Volume 58, Issue 4, Page(s) 327–328

    Language English
    Publishing date 2023-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1468893-1
    ISSN 0018-5787
    ISSN 0018-5787
    DOI 10.1177/00185787231158772
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    Zs.B 1758: Show issues Location:
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  2. Article: How much does the postoperative delirium really count as a risk factor for poorer quality of life with long-term cognitive and functional decline after cardiac surgery?

    Samara, Evangelia / Karakosta, Agathi / Tachias, Frixos / Tzimas, Petros

    Indian journal of thoracic and cardiovascular surgery

    2023  Volume 39, Issue 4, Page(s) 431–434

    Language English
    Publishing date 2023-03-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2164386-6
    ISSN 0973-7723 ; 0970-9134
    ISSN (online) 0973-7723
    ISSN 0970-9134
    DOI 10.1007/s12055-023-01502-x
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  3. Article ; Online: Accidental Administration of Mega-Dose-Morphine Intrathecally.

    Samara, Evangelia / Karakosta, Agathi / Tsionaras, Vasilios / Tzimas, Petros

    Journal of pain & palliative care pharmacotherapy

    2023  Volume 37, Issue 3, Page(s) 221–222

    MeSH term(s) Humans ; Morphine/adverse effects ; Naloxone ; Injections, Spinal
    Chemical Substances Morphine (76I7G6D29C) ; Naloxone (36B82AMQ7N)
    Language English
    Publishing date 2023-06-14
    Publishing country England
    Document type Letter
    ZDB-ID 2078852-6
    ISSN 1536-0539 ; 1536-0288
    ISSN (online) 1536-0539
    ISSN 1536-0288
    DOI 10.1080/15360288.2023.2219666
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  4. Article ; Online: Training Requirements in Point-of-Care Ultrasonography of the Upper Airway: A Feasibility Study.

    Karakosta, Agathi / Pantazi, Danai / Margariti, Persefoni / Micha, Georgia / Samara, Evangelia / Tzimas, Petros

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2023  Volume 42, Issue 11, Page(s) 2513–2522

    Abstract: Objectives: Point-of-care ultrasonography of the upper airway can be a useful supplement to conventional pre-anesthetic clinical evaluations. However, the reliability of such examinations is highly operator-dependent and proper training in sonoanatomy ... ...

    Abstract Objectives: Point-of-care ultrasonography of the upper airway can be a useful supplement to conventional pre-anesthetic clinical evaluations. However, the reliability of such examinations is highly operator-dependent and proper training in sonoanatomy and ultrasound operational skills are required. The objective of this study aims to assess the minimum training requirements for applying a predefined upper airway scanning protocol in healthy volunteers by anesthesia trainees.
    Methods: Twenty-two healthy volunteer members of the Operating Room staff participated in the study. A predefined scanning protocol that included the identification of specific structures (hyoid bone, vocal cords, thyrohyoid membrane/epiglottis/pre-epiglottic space, cricothyroid membrane, and thyroid gland), as well as the performance of specific measurements (distance from the hyoid bone to skin, anterior commissure to skin, epiglottis to skin, and thyroid isthmus to skin) was taught in a single-day training course. The trainees' competence was assessed after multiple scanning repetitions performed over a week. Mixed effects regression models were applied for the trainee-instructor differences in all ultrasound measurements.
    Results: Cricothyroid membrane visualization had the lowest success rate (88%). Trainee-instructor differences were statistically significant for hyoid bone-to-skin (P < .001) and epiglottis-to-skin distances (P = .016). Measurement of the distance from the epiglottis to the skin required more scanning repetitions to achieve minimum deviance compared with other measurements. Ten or fewer scanning repetitions were sufficient to achieve minimum deviance for all four measurements.
    Conclusions: At least 10 scanning repetitions of a pre-defined upper airway scanning protocol can be used as the minimum standard for training.
    MeSH term(s) Humans ; Point-of-Care Systems ; Feasibility Studies ; Reproducibility of Results ; Trachea ; Ultrasonography
    Language English
    Publishing date 2023-06-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.1002/jum.16284
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  5. Article: The Effect of Cell Salvage on Bleeding and Transfusion Needs in Cardiac Surgery.

    Tachias, Frixos / Samara, Evangelia / Petrou, Anastasios / Karakosta, Agathi / Siminelakis, Stavros / Apostolakis, Efstratios / Tzimas, Petros

    Anesthesiology research and practice

    2022  Volume 2022, Page(s) 3993452

    Abstract: Introduction: Cell salvaging is well established in the blood management of cardiac patients, but there remain some concerns about its effects on perioperative bleeding and transfusion variables. This randomized controlled study investigated the ... ...

    Abstract Introduction: Cell salvaging is well established in the blood management of cardiac patients, but there remain some concerns about its effects on perioperative bleeding and transfusion variables. This randomized controlled study investigated the potential effects of the centrifuged end-product on bleeding, transfusion rates, and other transfusion-related variables in adult cardiac surgery patients submitted to extracorporeal circulation.
    Materials and methods: Patients were randomly chosen to receive (cell-salvage group, 99 patients) or not to receive (control group, 110 patients) the centrifuged product of a cell salvage apparatus. Bleeding and transfusion rates according to the universal definition of perioperative bleeding (UDPB) classification, postoperative hemoglobin, coagulation, and oxygenation indices were recorded and compared between the groups.
    Results: Both groups had almost identical bleeding and transfusion rates (median value: 2 units of red blood cells (RBC) and no units of fresh frozen plasma (FFP) and platelets (PLT) for both groups,
    Conclusion: Within the study's constraints, the perioperative use of the cell salvage concentrate does not seem to affect bleeding or transfusion variables, although it could probably ameliorate postoperative oxygenation in adult cardiac surgery patients. A tendency to promote coagulation disturbances was detected.
    Language English
    Publishing date 2022-09-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2397574-X
    ISSN 1687-6970 ; 1687-6962
    ISSN (online) 1687-6970
    ISSN 1687-6962
    DOI 10.1155/2022/3993452
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  6. Article ; Online: Long-term outcomes of thoracic endovascular aortic repair for the treatment of descending thoracic aortic aneurysms: a systematic review and meta-analysis.

    Karaolanis, Georgios I / Georgakarakos, Efstratios / Karakosta, Agathi / Glantzounis, Georgios K / Moulakakis, Konstantinos G / Dorweiler, Bernhard / Mylonas, Spyridon N

    The Journal of cardiovascular surgery

    2023  

    Abstract: Introduction: We undertook a systematic review of the currently published literature on TEVAR for DTAAs and we combined the eligible studies into a meta-analysis with the intention of evaluating the efficacy and the long-term durability of this ... ...

    Abstract Introduction: We undertook a systematic review of the currently published literature on TEVAR for DTAAs and we combined the eligible studies into a meta-analysis with the intention of evaluating the efficacy and the long-term durability of this treatment option.
    Evidence acquisition: A systematic search of the literature from January 2015 up to December 2022 was performed according to the PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines. For events during follow up we calculated the incidence rates (IRs) with 95% confidence intervals (95% CIs) per 100 patient-years (p-ys) as the number of patients with outcome events occurring during the specific time period divided by the total number of p-ys.
    Evidence synthesis: A total of 4127 study titles were identified by the initial search strategy, of which 12 were considered eligible for inclusion in the meta-analysis. A Total of 1976 patients (62% male) were identified among the eligible studies. One-year survival was 90.1% (95% CI 86.3% to 93.0%), 3-year survival was estimated at 80.5% (95% CI 69.2% to 88.4%) and the 5-year survival was estimated at 73.2% (95%CI 64.3% to 80.5%) with significant heterogeneity among studies regarding these outcomes. Regarding freedom from reintervention analysis for 1 year and 5 years was 96.5% (95% CI 94.5% to 97.8%) and 85.4% (95% CI 56.7% to 96.3%) respectively. The pooled late complications IR per 100 p-ys was 55.0 (95% CI 39.1 to 70.9), whereas the pooled IR for late reinterventions per 100 p-ys was 21.2 (95% CI 26.0 to 87.5). Late type I endoleak was reported with a pooled IR of 26.7 per 100 p-ys (95% CI 19.8 to 33.6) and late type III endoleak with a pooled IR of 7.6 per 100 p-ys (95% CI 5.5 to 9.7).
    Conclusions: TEVAR presents a safe and feasible solution for the treatment of DTAA with sustained long-term effectivity. Current evidence supports a satisfactory 5-year survival with low rates of reinterventions.
    Language English
    Publishing date 2023-06-19
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    DOI 10.23736/S0021-9509.23.12648-6
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    Zs.A 469: Show issues Location:
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  7. Article: Anesthetic Management of A Patient with Charcot-Marie-Tooth Disease for 2-stage Revision of Total Knee Replacement.

    Soulioti, Eleftheria / Kavezou, Foteini / Efstathiou, Georgia / Batistaki, Chrysanthi / Karakosta, Agathi / Kostopanagiotou, Georgia

    Turkish journal of anaesthesiology and reanimation

    2021  Volume 49, Issue 2, Page(s) 178–180

    Abstract: Charcot-Marie-Tooth disease is characterised by hereditary motor and sensory neuropathy. Its anaesthetic management is challenging owing to the unpredictable response observed in patients, especially to non-depolarising neuromuscular blocking drugs, and ... ...

    Abstract Charcot-Marie-Tooth disease is characterised by hereditary motor and sensory neuropathy. Its anaesthetic management is challenging owing to the unpredictable response observed in patients, especially to non-depolarising neuromuscular blocking drugs, and the risk of malignant hyperthermia and cardiorespiratory complications. A 66-year-old woman underwent anaesthesia for 2 different surgical procedures, a 2-stage revision of total knee replacement over a 4-month period. She presented with severe anatomic disorders, accompanied by severe motor and sensory impairment. An anaesthetic plan without neuromuscular blocking drugs or volatile anaesthetics, using a clean ventilator, with dantrolene available, was successfully used both times. There were no complications during the administration of general anaesthesia or postoperatively at the post-anaesthesia care unit, and the patient did not complain of pain at any time. General anaesthesia with a careful selection of anaesthetic drugs proved to be a safe option for the management of a patient with Charcot-Marie-Tooth disease.
    Language English
    Publishing date 2021-04-01
    Publishing country Turkey
    Document type Case Reports
    ISSN 2667-677X
    ISSN 2667-677X
    DOI 10.5152/TJAR.2021.513
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  8. Article: Pulsed Radiofrequency of the Occipital Nerves: Results of a Standardized Protocol on Chronic Headache Management.

    Batistaki, Chrysanthi / Madi, Alia Ibrahim / Karakosta, Agathi / Kostopanagiotou, Georgia / Arvaniti, Chrysa

    Anesthesiology and pain medicine

    2021  Volume 11, Issue 5, Page(s) e112235

    Abstract: Background: Pulsed radiofrequency (PRF) of the occipital nerves has neuromodulative properties and is used for chronic pain management. However, its role in various types of chronic headaches has not been adequately investigated so far.: Objectives: ... ...

    Abstract Background: Pulsed radiofrequency (PRF) of the occipital nerves has neuromodulative properties and is used for chronic pain management. However, its role in various types of chronic headaches has not been adequately investigated so far.
    Objectives: Τhis was an observational, open-label, prospective study aiming to assess the efficacy of PRF of occipital nerves on various types of chronic headache management.
    Methods: Patients with chronic headaches followed up at the pain management unit were scheduled for PRF of both occipital nerves after a positive diagnostic nerve block. PRF was applied following a standardized protocol at 42°C, and the number of headaches per month was assessed as a primary outcome at baseline (before treatment), as well as after 1, 3, and 6 months. Pain intensity during headache crises was recorded using the Numeric Rating Scale (NRS, 0 - 10).
    Results: Fifty-seven patients suffering from chronic migraines, cluster headaches, tension-type headaches, and occipital neuralgia were studied. PRF significantly improved the number of headache episodes per month, as well as the pain intensity of the crises. The median number of headache episodes per month was significantly reduced in patients with migraine, from 14.5 to 4 after 1 month, and to 6.5 after 6 months. The same was seen for patients with clusters, who were also improved. A statistically significant reduction in NRS values over time was seen for all types of headaches.
    Conclusions: PRF of the occipital nerves can lead to a reduction of the number of headache episodes per month, improving the intensity of pain during each episode.
    Language English
    Publishing date 2021-10-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 3018888-X
    ISSN 2228-7531 ; 2228-7523
    ISSN (online) 2228-7531
    ISSN 2228-7523
    DOI 10.5812/aapm.112235
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  9. Article ; Online: Systemic Thrombolysis for Treatment of Acute Life-threatening Pulmonary Embolism During Cesarean Section Followed by Post-partum Rescue Hysterectomy: A Case Report and Review of the Literature.

    Karakosta, Agathi / Evangelou, Theocharis / Flindris, Stefanos / Samara, Ioanna / Styliara, Effrosyni / Dalkalitsis, Alexandros / Pantazi, Danai / Bolosi, Maria / Argyri, Urania / Michalis, Lampros K / Argyropoulou, Maria I / Naurozoglou, Iordanis / Paschopoulos, Minas / Tzimas, Petros

    In vivo (Athens, Greece)

    2023  Volume 37, Issue 1, Page(s) 498–502

    Abstract: Background/aim: Acute pulmonary embolism during cesarean section is extremely rare and only a limited number of cases have been reported in literature. The aim of this study was to report a case of acute high risk pulmonary embolism during elective ... ...

    Abstract Background/aim: Acute pulmonary embolism during cesarean section is extremely rare and only a limited number of cases have been reported in literature. The aim of this study was to report a case of acute high risk pulmonary embolism during elective cesarean section treated with systemic thrombolysis and discuss the multidisciplinary management in both early recognition and prompt treatment.
    Case report: A 39-year-old, G5P2, ASA II parturient presented for repeat cesarean section under general anesthesia. A sudden drop in end-tidal CO
    Conclusion: Though pregnancy is one of the major risk factors of the development of venous thromboembolism, acute intraoperative pulmonary embolism is extremely rare. Specific guidelines for the management of such cases are difficult to issue due to the paucity of relevant data. Thus, an individualized approach by a multidisciplinary team for diagnosis and intervention is mandated.
    MeSH term(s) Pregnancy ; Humans ; Female ; Adult ; Cesarean Section/adverse effects ; Tissue Plasminogen Activator ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/drug therapy ; Pulmonary Embolism/etiology ; Hysterectomy/adverse effects ; Thrombosis/surgery ; Thrombolytic Therapy/adverse effects ; Postpartum Period
    Chemical Substances Tissue Plasminogen Activator (EC 3.4.21.68)
    Language English
    Publishing date 2023-01-03
    Publishing country Greece
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 807031-3
    ISSN 1791-7549 ; 0258-851X
    ISSN (online) 1791-7549
    ISSN 0258-851X
    DOI 10.21873/invivo.13106
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    Zs.A 2288: Show issues Location:
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  10. Article ; Online: High Prevalence of Small Intestinal Bacterial Overgrowth Syndrome in ICU Patients: An Observational Study.

    Karakosta, Agathi / Bousvaros, Konstantinos / Margaritis, Athanasios / Moschovi, Ploumi / Mousafiri, Ourania / Fousekis, Fotios / Papathanakos, Georgios / Samara, Evangelia / Tzimas, Petros / Christodoulou, Dimitrios / Koulouras, Vasilios / Baltayiannis, Gerasimos

    Journal of intensive care medicine

    2023  Volume 39, Issue 1, Page(s) 69–76

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Humans ; Blind Loop Syndrome/complications ; Critical Illness/epidemiology ; Intensive Care Units ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/etiology ; Prevalence ; Prospective Studies
    Language English
    Publishing date 2023-07-24
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 632828-3
    ISSN 1525-1489 ; 0885-0666
    ISSN (online) 1525-1489
    ISSN 0885-0666
    DOI 10.1177/08850666231190284
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