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Article: Duct stenting in an ELBW infant with aortic arch interruption.

Anagnostopoulou, Andriana S / Karanasios, Evangelos S / Eleftherakis, Nicholaos G

2022 Volume 15, Issue 2, Page(s) 203–205

Abstract: Aortic arch interruption is a rare cardiac malformation. In some cases, it is part of a more complex congenital heart disease. Survival of extremely low birth weight infants with this cardiac disease is very rare. Surgical correction is the only ... ...

Abstract	Aortic arch interruption is a rare cardiac malformation. In some cases, it is part of a more complex congenital heart disease. Survival of extremely low birth weight infants with this cardiac disease is very rare. Surgical correction is the only treatment. Ductal stenting as a bridge procedure in small affected infants is a good alternative.
Language	English
Publishing date	2022-08-19
Publishing country	India
Document type	Case Reports
ZDB-ID	2430956-4
ISSN	0974-5149 ; 0974-2069
ISSN (online)	0974-5149
ISSN	0974-2069
DOI	10.4103/apc.apc_121_21
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Article ; Online: The prevalence of underweight and obesity in CHD. Response to body mass index and age are associated with ventricular end-diastolic pressure in adults with a Fontan circulation.

Anagnostopoulou, Andriana / Eleftherakis, Nicholaos G / Karanasios, Evangelos

Cardiology in the young

2022 Volume 32, Issue 11, Page(s) 1873–1874

Abstract: Introduction: The aim of the study is to determine the impact of obesity in children with CHD which is severe enough to require invasive catheterisation.: Methodology: This is a retrospective study in a cardiac catheterisation laboratory of a large ... ...

Abstract	Introduction: The aim of the study is to determine the impact of obesity in children with CHD which is severe enough to require invasive catheterisation. Methodology: This is a retrospective study in a cardiac catheterisation laboratory of a large paediatric hospital. The material consisted of 378 children from 2 to 19 years old who underwent heart catheterisation in the years 2011-2019. Their anthropometric data were collected, and the body mass index was calculated. The BMI centile was then calculated according to the Centers for Diseases Control (CDC). They were classified as overweight (85-95th centile), obese (> 95th centile), normal weight (5th-85 centile), and underweight (< 5th centile). Results: 18.7% of children were underweight, 54.76% were normal weight, 11.64% were overweight, and 14.81% were obese. Overall, 26.45% of the children were overweight. Boys were more likely to have increased body weight than girls, but the difference was not statistically significant. The percentage of increased weight was similar in children with acyanotic CHD as well as heart disease from other causes. On the contrary, children with cyanotic heart disease were more likely to be younger and have a higher percentage of underweight children. Conclusions: The rates of obesity and overweight in children with CHD depend on the sex, age, and cardiopathy type. In addition, they agree with the findings that have been published in international series studies for children with CHD.
MeSH term(s)	Child ; Adult ; Male ; Female ; Humans ; Child, Preschool ; Adolescent ; Young Adult ; Thinness/complications ; Thinness/epidemiology ; Body Mass Index ; Overweight ; Prevalence ; Pediatric Obesity/complications ; Pediatric Obesity/epidemiology ; Fontan Procedure ; Retrospective Studies ; Blood Pressure ; Heart Diseases
Language	English
Publishing date	2022-10-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1078466-4
ISSN	1467-1107 ; 1047-9511
ISSN (online)	1467-1107
ISSN	1047-9511
DOI	10.1017/S1047951122003304
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Article ; Online: Longitudinal Cardiac Evaluation of Children with Multisystem Inflammatory Syndrome (MIS-C) Following COVID-19 by Conventional and Speckle-Tracking Echocardiography.

Anagnostopoulou, Andriana / Dourdouna, Maria-Myrto / Loukopoulou, Sofia / Mpourazani, Evdoxia / Poulakis, Marios / Karanasios, Evangelos / Michos, Athanasios

Pediatric cardiology

2024 Volume 45, Issue 5, Page(s) 1110–1119

Abstract: Multisystem inflammatory syndrome in children (MIS-C), is a rare but severe, hyperinflammatory complication of COVID-19, in which cardiovascular abnormalities are frequently detected. In this prospective study, we describe the echocardiographic findings ... ...

Abstract	Multisystem inflammatory syndrome in children (MIS-C), is a rare but severe, hyperinflammatory complication of COVID-19, in which cardiovascular abnormalities are frequently detected. In this prospective study, we describe the echocardiographic findings in patients with MIS-C, with the use of conventional Echocardiography and Speckle-Tracking Echocardiography (STE) with Left Ventricular (LV) Global Longitudinal Strain (GLS) analysis, in the acute and follow-up phase. In total, 25 MIS-C patients [64% females, mean (± SD) age: 8.3 (± 3.72) years] were included. In the acute phase, median (IQR) Troponin and NT-proBNP and mean heart rate, were 8.07 (14.52) pg/mL, 2875.00 (7713.00) pg/mL, and 102.87 (± 22.96) bpm, respectively. Median (IQR) LV Ejection Fraction (LVEF) was 66 (8)% and LVEF impairment was detected in 2/25 (8%) patients. On follow-up (mean time interval:9.50 ± 4.59 months), heart rate was significantly lower, with a mean value of 90.00 (± 14.56) bpm (p-value = 0.017). Median (IQR) LVEF was 66.00 (6.70)% (p-value = 0.345) and all 25 participants had normal LVEF. In 14/25 patients, additional LV-GLS analysis was performed. During the acute phase, mean LV-GLS was - 18.02 (± 4.40)%. LV-GLS was abnormal in 6/14 patients (42.9%) and among them, only one patient had reduced LVEF. On follow-up (median (IQR) time interval:6.93 (3.66) months), mean LV-GLS was -20.31 (± 1.91)% (p-value = 0.07) and in 1/14 patient (7.1%), the LV-GLS impairment persisted. In conclusion, in the acute and follow-up phase, we detected abnormal LV-GLS values in some patients, in the presence of normal LVEF, indicating that STE-GLS is a valuable tool for identifying subclinical myocardial injury in MIS-C.
MeSH term(s)	Humans ; Female ; COVID-19/complications ; Systemic Inflammatory Response Syndrome/diagnostic imaging ; Systemic Inflammatory Response Syndrome/diagnosis ; Child ; Male ; Echocardiography/methods ; Prospective Studies ; SARS-CoV-2 ; Child, Preschool ; Adolescent ; Stroke Volume ; Natriuretic Peptide, Brain/blood ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/etiology ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Function, Left ; Peptide Fragments/blood ; Longitudinal Studies
Chemical Substances	Natriuretic Peptide, Brain (114471-18-0) ; pro-brain natriuretic peptide (1-76) ; Peptide Fragments
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	800857-7
ISSN	1432-1971 ; 0172-0643
ISSN (online)	1432-1971
ISSN	0172-0643
DOI	10.1007/s00246-023-03375-8
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Article: Markedly elevated troponin and NT-proBNP and myocardial dysfunction in an adolescent with severe diabetic ketoacidosis: A case report.

Sakou, Irine-Ikbale / Soldatou, Alexandra / Seretis, Aristeidis / Karanasios, Evangelos / Paltoglou, George / Karavanaki, Kyriaki

Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology

2022 Volume 31, Issue 3, Page(s) 192–198

Abstract: Severe diabetic ketoacidosis (DKA), rarely, may be associated with elevated troponin and proBNP levels in adults with a history of diabetes. However, few cases have reported this association in children with severe and complicated DKA. We describe a case ...

Abstract	Severe diabetic ketoacidosis (DKA), rarely, may be associated with elevated troponin and proBNP levels in adults with a history of diabetes. However, few cases have reported this association in children with severe and complicated DKA. We describe a case of severe DKA (pH: 6.89, HCO3: 6.5) in a 14-yr-old female adolescent in which the symptoms of DKA were presented days before the diagnosis. The patient was under the effect of acidosis (Kussmaul respiration) for 12 h before admission to our hospital, where she was admitted in a critical clinical condition. After successful treatment with DKA with intensive intravenous fluid and regular insulin, the patient presented with abnormal cardiac rhythm, disturbance of interventricular septum motility, a mild decrease in left ventricular systolic function, negative T waves in leads III and aVF, and a marked increase in troponin and brain natriuretic peptide (NT-proBNP) levels. All abnormal findings completely resolved within 8 days after the initiation of DKA treatment. The phenomenon in our case was transient, and the patient had a good long-term outcome. However, it represents a challenge for clinicians; therefore, emphasis should be given to cardiac monitoring during the course of severe and prolonged DKA in children and adolescents.
Language	English
Publishing date	2022-05-16
Publishing country	Japan
Document type	Case Reports
ZDB-ID	2079760-6
ISSN	0918-5739
ISSN	0918-5739
DOI	10.1297/cpe.2022-0017
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Article: Recurrent arterial ischemic strokes in a patient with patent foramen ovale and ductus arteriosus: Presentation of our management and review of the literature.

Panagopoulos, Dimitrios / Loukopoulou, Sofia / Karanasios, Evangelos / Eleftherakis, Nikolaos

Global cardiology science & practice

2019 Volume 2019, Issue 2, Page(s) e201913

Abstract: Ischemic stroke in children is a relatively rare entity, relative to the adult population. The most common potential risk factors include cardiac embolism, prothrombotic states and vasculopathies. The diagnosis is concerning for the need to identify the ... ...

Abstract	Ischemic stroke in children is a relatively rare entity, relative to the adult population. The most common potential risk factors include cardiac embolism, prothrombotic states and vasculopathies. The diagnosis is concerning for the need to identify the underlying cause. Treatment of the proximate source of ischemia can often protect against future events. We present the case of a 7-year-old patient who initially presented with an ischemic brain insult which was repeated, despite the initiation of anticoagulation therapy. The investigation revealed patent foramen ovale and patent ductus arteriosus and because of the recurrent ischemic ictuses, transcatheter closure of both defects was decided. A brief description of the literature is also presented.
Language	English
Publishing date	2019-09-20
Publishing country	Qatar
Document type	Case Reports
ZDB-ID	2738381-7
ISSN	2305-7823
ISSN	2305-7823
DOI	10.21542/gcsp.2019.13
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Article ; Online: Targeted Multiresidue Method for the Analysis of Different Classes of Pesticides in Agro-Food Industrial Sludge by Liquid Chromatography Tandem Mass Spectrometry.

Maragou, Niki C / Balayiannis, George / Karanasios, Evangelos / Markellou, Emilia / Liapis, Konstantinos

Molecules (Basel, Switzerland)

2021 Volume 26, Issue 22

Abstract: Sludge generated after washing of fruits and vegetables during agro-food processes is a complex matrix and selective methods for the identification and quantification of pesticides' residues are necessary in order to achieve a sustainable and effective ... ...

Abstract	Sludge generated after washing of fruits and vegetables during agro-food processes is a complex matrix and selective methods for the identification and quantification of pesticides' residues are necessary in order to achieve a sustainable and effective management of the total sewage. The present work describes the development and validation of a reliable, simple and fast analytical method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the determination of 47 pesticides of different chemical classes, including organosphosphates, pyrethroids, neonicotinoids, triazoles and others, in sludge samples after QuEChERS sample preparation. The necessity of the individual steps of QuEChERS was investigated and the LC-ESI-MS/MS conditions were optimized to achieve maximum sensitivity of the target analytes. The method limits of detection (LODs) ranged between 0.0005 mg/kg (imidacloprid) and 0.05 mg/kg (beta cyfluthrin). The recoveries ranged between 71-120% and the repeatability of the method was ≤25% expressed as relative standard deviation. The method was applied to sludge samples generated after washing of fruits in an agro-fruit-packaging unit in Greece. The results showed the presence of 37 pesticides' active substances with concentrations ranging from low ppbs, such as fludioxinil (5 μg/kg) up to low ppms such as beta cyfluthrin (3.5 mg/kg) and with their sum concentration reaching up to 19 mg/kg.
MeSH term(s)	Chromatography, Liquid/methods ; Limit of Detection ; Pesticides/analysis ; Reproducibility of Results ; Sewage/analysis ; Solid Phase Extraction/methods ; Tandem Mass Spectrometry/methods
Chemical Substances	Pesticides ; Sewage
Language	English
Publishing date	2021-11-15
Publishing country	Switzerland
Document type	Journal Article ; Validation Study
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules26226888
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Article: Heart Failure Post-SARS-CoV-2 Infection in Children with Duchenne Muscular Dystrophy: The Additive Value of Cardiovascular Magnetic Resonance.

Markousis-Mavrogenis, George / Belegrinos, Antonios / Giannakopoulou, Aikaterini / Karanasios, Evangelos / Vartela, Vasiliki / Patsilinakou, Elephtheria / Samantis, Paul / Pons, Roser-Marie / Papavasiliou, Antigoni / Mavrogeni, Sophie I

Children (Basel, Switzerland)

2023 Volume 10, Issue 5

Abstract: In this case series, we describe the diagnosis of post-COVID-19 myocarditis in asymptomatic patients with Duchenne Muscular Dystrophy (DMD) and a mild COVID-19 disease course. These patients were referred for CMR due to electrocardiographic and ... ...

Abstract	In this case series, we describe the diagnosis of post-COVID-19 myocarditis in asymptomatic patients with Duchenne Muscular Dystrophy (DMD) and a mild COVID-19 disease course. These patients were referred for CMR due to electrocardiographic and echocardiographic alterations, which did not exist before COVID-19 infection. CMR identified the presence of severe myocardial inflammation in all patients based on abnormally elevated myocardial T2 ratio, late gadolinium enhancement, native T1 mapping, T2 mapping, and extracellular volume fraction. This was paired with concurrent impairment of left ventricular function. Appropriate treatment was initiated in all cases. Two of the four patients developed episodes of ventricular tachycardia during the following 6 months, and a defibrillator was implanted. Despite the mild clinical presentation, this case series demonstrates the diagnostic strength of CMR in the diagnosis and evaluation of post-COVID-19 myocarditis and serves to increase awareness of this potential complication amongst treating physicians.
Language	English
Publishing date	2023-05-17
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children10050894
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Article ; Online: Monitoring of glyphosate and AMPA in soil samples from two olive cultivation areas in Greece: aspects related to spray operators activities.

Karanasios, Evangelos / Karasali, Helen / Marousopoulou, Anna / Akrivou, Antigoni / Markellou, Emilia

Environmental monitoring and assessment

2018 Volume 190, Issue 6, Page(s) 361

Abstract: The persistence of glyphosate and its primary metabolite AMPA (aminomethylphosphonic acid) was monitored in two areas in Southern Greece (Peza, Crete and Chora Trifilias, Peloponnese) with a known history of glyphosate use, and the levels of residues ... ...

Abstract	The persistence of glyphosate and its primary metabolite AMPA (aminomethylphosphonic acid) was monitored in two areas in Southern Greece (Peza, Crete and Chora Trifilias, Peloponnese) with a known history of glyphosate use, and the levels of residues were linked to spray operators' activities in the respective areas. A total of 170 samples were collected and analysed from both areas during a 3-year monitoring study. A new method (Impact Assessment Procedure - IAP) designed to assess potential impacts to the environment caused by growers' activities, was utilised in the explanation of the results. The level of residues was compared to the predicted environmental concentrations in soil. The ratio of the measured concentrations to the predicted environmental concentrations (MCs/PECs) was > 1 in Chora the first 2 years of sampling and < 1 in the third year, whilst the MCs/PECs ratio was < 1 in Peza, throughout the whole monitoring period. The compliance to the instructions for best handling practices, which operators received during the monitoring period, was reflected in the amount of residues and the MCs/PECs ratio in the second and especially the third sampling year. Differences in the level of residues between areas as well as sampling sites of the same area were identified. AMPA persisted longer than the parent compound glyphosate in both areas.
MeSH term(s)	Agriculture ; Environmental Monitoring ; Glycine/analogs & derivatives ; Glycine/analysis ; Greece ; Herbicides/analysis ; Olea ; Soil/chemistry ; Soil Pollutants/analysis ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/analysis ; Glyphosate
Chemical Substances	Herbicides ; Soil ; Soil Pollutants ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (77521-29-0) ; Glycine (TE7660XO1C)
Language	English
Publishing date	2018-05-25
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-018-6728-x
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Article: Monitoring of glyphosate and AMPA in soil samples from two olive cultivation areas in Greece: aspects related to spray operators activities

Karanasios, Evangelos / Anna Marousopoulou / Antigoni Akrivou / Emilia Markellou / Helen Karasali

Environmental monitoring and assessment. 2018 June, v. 190, no. 6

2018

Abstract	The persistence of glyphosate and its primary metabolite AMPA (aminomethylphosphonic acid) was monitored in two areas in Southern Greece (Peza, Crete and Chora Trifilias, Peloponnese) with a known history of glyphosate use, and the levels of residues were linked to spray operators’ activities in the respective areas. A total of 170 samples were collected and analysed from both areas during a 3-year monitoring study. A new method (Impact Assessment Procedure - IAP) designed to assess potential impacts to the environment caused by growers’ activities, was utilised in the explanation of the results. The level of residues was compared to the predicted environmental concentrations in soil. The ratio of the measured concentrations to the predicted environmental concentrations (MCs/PECs) was > 1 in Chora the first 2 years of sampling and < 1 in the third year, whilst the MCs/PECs ratio was < 1 in Peza, throughout the whole monitoring period. The compliance to the instructions for best handling practices, which operators received during the monitoring period, was reflected in the amount of residues and the MCs/PECs ratio in the second and especially the third sampling year. Differences in the level of residues between areas as well as sampling sites of the same area were identified. AMPA persisted longer than the parent compound glyphosate in both areas.
Keywords	compliance ; cultivation area ; glyphosate ; growers ; metabolites ; monitoring ; olives ; soil ; soil sampling ; Crete ; Greece
Language	English
Dates of publication	2018-06
Size	p. 361.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-018-6728-x
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Haddad Syndrome.

Tsoutsinos, Alexander / Karanasios, Evangelos / Chatzis, Andrew C

Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese

2015 Volume 57, Issue 1, Page(s) 45–47

Abstract: Congenital central hypoventilation syndrome (CCHS) causes predominantly sleep apnoea and is one of a growing number of inherited disorders characterised by autonomic nervous system dysfunction/dysregulation (ANSD). In association with Hirschsprung's ... ...

Abstract	Congenital central hypoventilation syndrome (CCHS) causes predominantly sleep apnoea and is one of a growing number of inherited disorders characterised by autonomic nervous system dysfunction/dysregulation (ANSD). In association with Hirschsprung's disease (HSCR), it presents as Haddad's syndrome. We report a case of Haddad's syndrome complicated by sinus node dysfunction.
MeSH term(s)	Child, Preschool ; Heart Diseases/physiopathology ; Heart Diseases/therapy ; Humans ; Hypoventilation/complications ; Hypoventilation/congenital ; Male ; Pacemaker, Artificial ; Sinoatrial Node/physiopathology ; Sleep Apnea, Central/complications ; Treatment Outcome
Language	English
Publishing date	2015-07-02
Publishing country	Netherlands
Document type	Case Reports ; Journal Article
ZDB-ID	2215027-4
ISSN	2241-5955 ; 1109-9666
ISSN (online)	2241-5955
ISSN	1109-9666
DOI	10.1016/s1109-9666(16)30019-7
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