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Article ; Online: Should Calcineurin Inhibitors/Sirolimus Be Ceased Completely In Posterior Reversible Encephalopathy Syndrome?

Karataş, Cihan / Akyollu, Başak / Arpalı, Emre / Kocak, Burak

2024 Volume 56, Issue 1, Page(s) 93–96

Abstract: Background: To investigate the relationship between immunosuppressive treatments and posterior reversible encephalopathy syndrome (PRES) in transplant patients.: Methods: We presented a retrospective study of 4 cases of PRES in transplant patients. ... ...

Abstract	Background: To investigate the relationship between immunosuppressive treatments and posterior reversible encephalopathy syndrome (PRES) in transplant patients. Methods: We presented a retrospective study of 4 cases of PRES in transplant patients. Patient records were reviewed to identify potential risk factors, clinical presentations, radiological findings, and immunosuppressive treatments used. Results: Our analysis revealed a potential association between immunosuppressive treatments and the development of PRES in transplant patients. Specifically, we found that adjusting or switching immunosuppressive treatments can improve outcomes and prevent the recurrence of PRES. Conclusion: Our findings highlight the importance of recognizing PRES as a potential complication of immunosuppressive treatments in transplant patients. Early detection and management, including a review of immunosuppressive treatments, may improve patient outcomes and prevent further complications.
MeSH term(s)	Humans ; Calcineurin Inhibitors/adverse effects ; Immunosuppressive Agents/adverse effects ; Posterior Leukoencephalopathy Syndrome/chemically induced ; Posterior Leukoencephalopathy Syndrome/diagnostic imaging ; Retrospective Studies ; Sirolimus
Chemical Substances	Calcineurin Inhibitors ; Immunosuppressive Agents ; Sirolimus (W36ZG6FT64)
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2023.11.012
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Article ; Online: Prognostic Factors of Liver Transplantation for HCC: Comparative Literature Review.

Alim, Altan / Karataş, Cihan

Journal of gastrointestinal cancer

2021 Volume 52, Issue 4, Page(s) 1223–1231

Abstract: Purpose: The aim of the review study is investigation of the prognostic factors of the liver transplantation for hepatocellular carcinoma.: Methods: A literature review has been made, especially in countries where dominantly living donor liver ... ...

Abstract	Purpose: The aim of the review study is investigation of the prognostic factors of the liver transplantation for hepatocellular carcinoma. Methods: A literature review has been made, especially in countries where dominantly living donor liver transplantation is performed, such as Turkey. Liver transplantation from deceased donor and from living donor has been evaluated about as advantages and disadvantages, and their effects on prognosis have been compared. In addition, hepatocellular carcinoma series of Koç University Liver Transplantation center has been presented. Results: Liver transplantation is still the best treatment option with 5-year 50% survival rate for hepatocellular carcinoma even in patient who has locally advanced tumor. The patient's survival is not only an important issue but also the living donor's safety is controversial particularly when expectation of recipient's 5-year survival is below 50% due to donor complication. Conclusion: Detailed preoperative examination, appropriate patient selection, and timing of surgery are seen the most important issues in liver transplant's patients with hepatocellular carcinoma.
MeSH term(s)	Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/surgery ; Humans ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Liver Transplantation/statistics & numerical data ; Neoplasm Grading ; Prognosis ; Risk Factors ; Survival Rate ; Treatment Outcome ; Turkey/epidemiology
Language	English
Publishing date	2021-12-09
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Review
ZDB-ID	2452514-5
ISSN	1941-6636 ; 1559-0739 ; 1941-6628 ; 1537-3649
ISSN (online)	1941-6636 ; 1559-0739
ISSN	1941-6628 ; 1537-3649
DOI	10.1007/s12029-021-00730-x
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Article: Experience of kidney transplantation to a patient with Bernard Soulier syndrome: A case report.

Karataş, Cihan / Akyollu, Başak / Arpalı, Emre / Yelken, Berna / Türkmen, Aydın / Koçak, Burak

Turkish journal of surgery

2023 Volume 39, Issue 1, Page(s) 86–88

Abstract: Renal transplantation could be a challenging operation in patients with haemorrhagic diathesis, with predictable difficulties or even with unpredictable hurdles. Bernard Soulier Syndrome (BSS) is one of the ethiologies of the thrombocytopenia and it is a ...

Abstract	Renal transplantation could be a challenging operation in patients with haemorrhagic diathesis, with predictable difficulties or even with unpredictable hurdles. Bernard Soulier Syndrome (BSS) is one of the ethiologies of the thrombocytopenia and it is a rare hereditary disease associated with defects of the platelet glycoprotein complex glycoprotein Ib/V/IX and characterized by large platelets, thrombocytopenia, and severe bleeding symptoms. Here, we present a challenging renal transplantation in BSS.
Language	English
Publishing date	2023-03-03
Publishing country	Turkey
Document type	Case Reports
ISSN	2564-6850
ISSN	2564-6850
DOI	10.47717/turkjsurg.2022.4567
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Article ; Online: Using Pericholedochal Varix Inflow for Complete Portal Vein Thrombosis in Living Donor Liver Transplantation: A Case Report.

Tırnova, İsmail / Karataş, Cihan / Mecit, Nesimi / Kanmaz, Turan / Kalayoğlu, Münci

Transplantation proceedings

2022 Volume 54, Issue 6, Page(s) 1654–1656

Abstract: One of the crucial steps of liver transplantation is to provide the portal inflow. Portal vein thrombosis is the most challenging factor to achieve. Using a pericholedochal varix for portal inflow in a patient with complete portal vein thrombosis in ... ...

Abstract	One of the crucial steps of liver transplantation is to provide the portal inflow. Portal vein thrombosis is the most challenging factor to achieve. Using a pericholedochal varix for portal inflow in a patient with complete portal vein thrombosis in living donor liver transplantation (LDLT) is a rare technique. We present our experience of a LDLT with PVT.
MeSH term(s)	Humans ; Liver Diseases/complications ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Living Donors ; Portal Vein/diagnostic imaging ; Portal Vein/surgery ; Varicose Veins/complications ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/etiology ; Venous Thrombosis/surgery
Language	English
Publishing date	2022-07-13
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2022.05.006
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Article ; Online: Literature Review and 2 Cases of Isolated Chylothorax After Pediatric Living-Donor Liver Transplant.

Tırnova, İsmail / Alim, Altan / Vehbi, Sezan / Demir, Barış / Akbulut, Akın / Karataş, Cihan / Kanmaz, Turan

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

2023 Volume 21, Issue 8, Page(s) 705–708

Abstract: Objectives: Chylothorax without chylous ascites after liver transplant is rare. We present 2 cases of isolated chylothorax after liver transplant and a literature review.: Materials and methods: We compiled a literature review of chylothorax cases ... ...

Abstract	Objectives: Chylothorax without chylous ascites after liver transplant is rare. We present 2 cases of isolated chylothorax after liver transplant and a literature review. Materials and methods: We compiled a literature review of chylothorax cases after abdominal surgery and analyzed the cases related to liver transplant. The demographic information, follow-up results, and treatment details of our 2 cases of chylothorax after living-donor pediatric livertransplant were discussed. Results: An 8-month-old child and a 15-month-old child with cholestatic liver disease and urea cycle defect, respectively, underwent living-donor left lateral segment liver transplant. Patients who presented with chylothorax after discharge were treated conservatively. Conclusions: Isolated chylothorax is rare complication after abdominal surgery, which is mostly possible to treat with conservative methods. Interventional procedures and a surgical approach should only be performed in resistant cases when conservative treatment has failed.
MeSH term(s)	Humans ; Child ; Infant ; Chylothorax/diagnostic imaging ; Chylothorax/etiology ; Chylothorax/therapy ; Liver Transplantation/adverse effects ; Living Donors ; Chylous Ascites/etiology
Language	English
Publishing date	2023-07-27
Publishing country	Turkey
Document type	Review ; Case Reports ; Journal Article
ZDB-ID	2396778-X
ISSN	2146-8427 ; 1304-0855
ISSN (online)	2146-8427
ISSN	1304-0855
DOI	10.6002/ect.2022.0251
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Zs.A 6632: Show issues

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Article ; Online: Hepatic Artery Intimal Dissection During Living Donor Liver Transplantation: A New Modified Approach.

Karataş, Cihan / Alim, Altan / Tirnova, Ismail / Demir, Barış / Akbulut, Akın / Kanmaz, Turan

Transplantation proceedings

2023 Volume 55, Issue 2, Page(s) 379–383

Abstract: Ensuring optimal arterial flow in solid organ transplantation is very important. Insufficient flow causes important problems such as bile duct problems, intrahepatic abscess formation, and organ loss. Arterial intimal dissection is an important factor ... ...

Abstract	Ensuring optimal arterial flow in solid organ transplantation is very important. Insufficient flow causes important problems such as bile duct problems, intrahepatic abscess formation, and organ loss. Arterial intimal dissection is an important factor that negatively affects organ blood flow. In this study, hepatic artery dissections that we detected in patients who underwent living donor liver transplantation in our clinic were defined, and the microvascular intima-adventitial fixation technique, which can be considered a new approach, was described.
MeSH term(s)	Humans ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Hepatic Artery/surgery ; Living Donors ; Carotid Intima-Media Thickness ; Liver
Language	English
Publishing date	2023-03-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2023.02.002
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Article ; Online: Anesthesia Management in Laparoscopic Donor Hepatectomy: The First Report from Turkey.

Akbulut, Akın / Alim, Altan / Karatas, Cihan / Oğuz, Bahadır Hakan / Kanmaz, Turan / Gürkan, Yavuz

Transplantation proceedings

2023 Volume 55, Issue 5, Page(s) 1166–1170

Abstract: Background: We aimed to report a single-center experience in laparoscopic donor left-side and right-side hepatectomy cases regarding preoperative evaluation, perioperative and anesthetic management protocols, and postoperative follow-up.: Methods: ... ...

Abstract	Background: We aimed to report a single-center experience in laparoscopic donor left-side and right-side hepatectomy cases regarding preoperative evaluation, perioperative and anesthetic management protocols, and postoperative follow-up. Methods: Laparoscopic donor left-side and right-side hepatectomy cases were included in the study because of their excessive transection area and bleeding potential. Medical records of living donors were reviewed in terms of age, sex, body mass index (BMI), presence of consanguinity with the recipient, perioperative and early postoperative biochemical parameters, hemodynamic changes during surgery, duration of surgery, the ratio of liver volume to total liver volume, perioperative complications, and length of hospital stay. Results: Eighty-one laparoscopic living-donor hepatectomy procedures were performed in our unit between 2018 and 2022. Six laparoscopic donor right-side cases and two left-side cases were retrospectively reviewed. Donors' mean age and BMI were 29.6 ± 8.6 years and 23.1 ± 4.3, respectively. The average weights of the right and left lobe liver grafts were 727 g and 279 g, respectively, constituting 65.8% and 22.7% of the total liver volume, respectively. The mean operation time was 593 ± 94 minutes, and the mean volume of blood loss was 437 ± 294 mL. A major complication, namely portal vein stenosis, developed in 1 donor (1/8), and portal vein patency was achieved postoperatively. Conclusions: Anesthesia management and teamwork between surgeons and anesthesiologists are the most important building blocks for donor safety, which is of the utmost priority. Effective communication and cooperation in the operating room may prevent potential donor complications and improve postoperative recovery time.
MeSH term(s)	Humans ; Hepatectomy/adverse effects ; Hepatectomy/methods ; Turkey ; Retrospective Studies ; Liver Transplantation/adverse effects ; Liver Transplantation/methods ; Liver/surgery ; Living Donors ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Anesthesia ; Postoperative Complications/surgery
Language	English
Publishing date	2023-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2023.01.033
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Article ; Online: Donor bile duct evaluation with magnetic resonance cholangiography in living-donor liver transplantation: a novel anatomical classification for predicting surgical techniques.

Karakaya, Afak Durur / Gündoğmuş, Cemal Aydın / Kanmaz, Turan / Karataş, Cihan / Kapakin, Samet

Diagnostic and interventional radiology (Ankara, Turkey)

2023 Volume 30, Issue 2, Page(s) 74–79

Abstract: Purpose: To propose a novel, inclusive classification that facilitates the selection of the appropriate donor and surgical technique in living-donor liver transplantation (LDLT).: Methods: The magnetic resonance cholangiography examinations of 201 ... ...

Abstract	Purpose: To propose a novel, inclusive classification that facilitates the selection of the appropriate donor and surgical technique in living-donor liver transplantation (LDLT). Methods: The magnetic resonance cholangiography examinations of 201 healthy liver donors were retrospectively evaluated. The study group was classified according to the proposed classification. The findings were compared with the surgical technique used in 93 patients who underwent transplantation. The Couinaud, Huang, Karakas, Choi, and Ohkubo classifications were also applied to all cases. Results: There were 118 right-lobe donors (58.7%) and 83 left-lateral-segment donors (41.3%). Fifty-six (28.8%) of the cases were classified as type 1, 136 (67.7%) as type 2, and 7 (3.5%) as type 3 in the proposed classification; all cases could be classified. The number of individuals able to become liver donors was 93. A total of 36 cases were type 1, 56 were type 2, and 1 was type 3. Of the type 1 donors, 83% required single anastomosis during transplantation, whereas six patients classified as type 1 required two anastomoses, all of which were caused by technical challenges during resection. Moreover, 51.8% of the cases classified as type 2 required additional anastomosis during transplantation. The type 3 patient required three anastomoses. The type 1 and type 2 donors required a different number of anastomoses ( Conclusion: The proposed classification in this study includes all anatomical variations. This inclusive classification accurately predicts the surgical technique for LDLT.
MeSH term(s)	Humans ; Liver Transplantation ; Living Donors ; Retrospective Studies ; Bile Ducts/diagnostic imaging ; Bile Ducts/surgery ; Cholangiography/methods ; Magnetic Resonance Spectroscopy
Language	English
Publishing date	2023-09-19
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2184145-7
ISSN	1305-3612 ; 1305-3612
ISSN (online)	1305-3612
ISSN	1305-3612
DOI	10.4274/dir.2023.232321
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Article ; Online: Cardiac Intervention Before Liver Transplantation.

Imam, Ashraf / Karatas, Cihan / Mecit, Nesimi / Kalayoglu, Munci / Kanmaz, Turan

Transplantation proceedings

2021 Volume 53, Issue 5, Page(s) 1622–1625

Abstract: Background: Cardiovascular complication is one of the leading causes of mortality after liver transplantation (LT). Thus, a thorough cardiac evaluation is a must before proceeding to a liver transplant surgery. Percutaneous coronary intervention (PCI) ... ...

Abstract	Background: Cardiovascular complication is one of the leading causes of mortality after liver transplantation (LT). Thus, a thorough cardiac evaluation is a must before proceeding to a liver transplant surgery. Percutaneous coronary intervention (PCI) with stent and to a lesser extent coronary artery bypass grafting (CABG) are both valuable treatment options for patients with coronary artery disease. Methods: A retrospective, single-center study that included patients who underwent cardiac intervention and subsequent LT for end-stage liver disease. All patients who had PCI or CABG were included in the study. Results: Twenty-nine adult patients out of 51 had a cardiac intervention before liver transplantation. Twenty-four patients had a diagnostic PCI, 3 patients had therapeutic PCI with stent, and 2 had failed PCI and proceeded to CABG before liver transplant. The mean age of the patients was 60.5 years. There were 24 men. All patients had cirrhosis. The 2 CABG cases were done during the same admission with a 13- and 18-day interval between the CABG and the transplantation. Both cases were live-related liver transplantation. No mortality was reported. Conclusion: In case of PCI failure, CABG may be a valuable and safe treatment option for cirrhotic patients as a preparation for liver transplantation. Live donor liver transplantation may be a good back-up for those patients in case they develop hepatic decompensation.
MeSH term(s)	Aged ; Coronary Artery Bypass ; Coronary Artery Disease/surgery ; Female ; Humans ; Liver Transplantation/adverse effects ; Living Donors ; Male ; Middle Aged ; Percutaneous Coronary Intervention ; Retrospective Studies
Language	English
Publishing date	2021-04-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2021.03.012
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Article ; Online: Patient With Hemophilia A Undergoing Consecutive Coronary Bypass and Live Donor Liver Transplantation: A Case Report.

Karatas, Cihan / Alim, Altan / Tirnova, Ismail / Demir, Barış / Kanmaz, Turan

Transplantation proceedings

2021 Volume 53, Issue 8, Page(s) 2564–2566

Abstract: Liver transplantation surgery due to cirrhosis in patients with hemophilia is rare and there are limited cases in the literature. We present a case of a patient with hemophilia A who underwent 2 consecutive surgeries owing to coronary artery disease and ... ...

Abstract	Liver transplantation surgery due to cirrhosis in patients with hemophilia is rare and there are limited cases in the literature. We present a case of a patient with hemophilia A who underwent 2 consecutive surgeries owing to coronary artery disease and cryptogenic cirrhosis with hepatocellular carcinoma. After these surgeries, no bleeding or other complications were seen, and the factor VIII levels have not changed since liver transplantation in the follow-up.
MeSH term(s)	Coronary Artery Bypass ; Hemophilia A/complications ; Hemophilia A/diagnosis ; Humans ; Liver Neoplasms/surgery ; Liver Transplantation ; Living Donors
Language	English
Publishing date	2021-09-14
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	82046-5
ISSN	1873-2623 ; 0041-1345
ISSN (online)	1873-2623
ISSN	0041-1345
DOI	10.1016/j.transproceed.2021.08.016
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