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  1. Book: Obesity: brain - gut and inflammation / Pt. 2

    Karnieli, Eddy

    (Endocrinology and metabolism clinics of North America ; 37,4)

    2008  

    Author's details guest ed. Eddy Karnieli
    Series title Endocrinology and metabolism clinics of North America ; 37,4
    Obesity ; brain - gut and inflammation
    Collection Obesity ; brain - gut and inflammation
    Language English
    Size XIII S., S. 811 - 984 : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015818468
    ISBN 978-1-4160-6292-9 ; 1-4160-6292-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 148 -37,4- verfügbar in Königswinter Königswinter

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  2. Book ; Collection: Obesity: brain - gut and inflammation

    Karnieli, Eddy

    (Endocrinology and metabolism clinics of North America ; ...)

    2008  

    Author's details guest ed. Eddy Karnieli
    Series title Endocrinology and metabolism clinics of North America
    ...
    Language English
    Dates of publication 2008-9999
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book ; Collection (display volumes)
    HBZ-ID HT015717257
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Obesity: brain - gut and inflammation / Pt. 1

    Karnieli, Eddy

    (Endocrinology and metabolism clinics of North America ; 37,3)

    2008  

    Author's details guest ed. Eddy Karnieli
    Series title Endocrinology and metabolism clinics of North America ; 37,3
    Obesity ; brain - gut and inflammation
    Collection Obesity ; brain - gut and inflammation
    Language English
    Size XVIII S., S. 559 - 810 : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015717265
    ISBN 978-1-4160-6291-2 ; 1-4160-6291-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 148 -37,3- verfügbar in Königswinter Königswinter

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  4. Book: Obesity

    LeRoith, Derek / Karnieli, Eddy

    (Medical clinics of North America ; 95,5)

    2011  

    Author's details guest ed. Derek LeRoith ; Eddy Karnieli
    Series title Medical clinics of North America ; 95,5
    Collection
    Language English
    Size XV S., S. 855 - 1040 : Ill., graph. Darst.
    Publisher Saunders an imprint of Elsevier
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT016988933
    ISBN 978-1-4557-2369-0 ; 1-4557-2369-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ua VI Zs 158 -95,5- verfügbar in Königswinter Königswinter

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  5. Article: Challenges of implementing personalized (precision) medicine: a focus on diabetes.

    Fodor, Adriana / Karnieli, Eddy

    Personalized medicine

    2016  Volume 13, Issue 5, Page(s) 485–497

    Abstract: The concept of personalized (precision) medicine (PM) emphasizes the scientific and technological innovations that enable the physician to tailor disease prediction, diagnosis and treatment to the individual patient, based on a personalized data-driven ... ...

    Abstract The concept of personalized (precision) medicine (PM) emphasizes the scientific and technological innovations that enable the physician to tailor disease prediction, diagnosis and treatment to the individual patient, based on a personalized data-driven approach. The major challenge for the medical systems is to translate the molecular and genomic advances into clinical available means. Patients and healthcare providers, the pharmaceutical and diagnostic industries manifest a growing interest in PM. Multiple stakeholders need adaptation and re-engineering for successful clinical implementation of PM. Drawing primarily from the field of 'diabetes', this article will summarize the main challenges to implementation of PM into current medical practice and some of the approaches currently being implemented to overcome these challenges.
    Language English
    Publishing date 2016-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2299146-3
    ISSN 1744-828X ; 1741-0541
    ISSN (online) 1744-828X
    ISSN 1741-0541
    DOI 10.2217/pme-2016-0022
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6549: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 73: Show issues

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  6. Article: The growing prevalence of obesity worldwide is an increasing concern. Preface.

    Karnieli, Eddy

    Endocrinology and metabolism clinics of North America

    2008  Volume 37, Issue 3, Page(s) xvii–xviii

    MeSH term(s) Humans ; Obesity/epidemiology ; Prevalence
    Language English
    Publishing date 2008-09
    Publishing country United States
    Document type Introductory Journal Article
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2008.07.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Preface. "Call to action" in fighting obesity.

    Karnieli, Eddy

    Endocrinology and metabolism clinics of North America

    2008  Volume 37, Issue 4, Page(s) xiii

    MeSH term(s) Adolescent ; Biomedical Research/trends ; Child ; Humans ; Obesity/complications ; Obesity/epidemiology ; Obesity/therapy ; United States/epidemiology
    Language English
    Publishing date 2008-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2008.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: TBC update: personalized epigenetic management of diabetes.

    Fodor, Adriana / Cozma, Angela / Karnieli, Eddy

    Personalized medicine

    2017  Volume 14, Issue 6, Page(s) 531–549

    Abstract: The novel genome-wide assays of epigenetic marks have resulted in a greater understanding of how genetics and the environment interact in the development and inheritance of diabetes. Chronic hyperglycemia induces epigenetic changes in multiple organs, ... ...

    Abstract The novel genome-wide assays of epigenetic marks have resulted in a greater understanding of how genetics and the environment interact in the development and inheritance of diabetes. Chronic hyperglycemia induces epigenetic changes in multiple organs, contributing to diabetic complications. Specific epigenetic-modifying compounds have been developed to erase these modifications, possibly slowing down the onset of diabetes-related complications. The current review is an update of the previously published paper, describing the most recent advances in the epigenetics of diabetes.
    MeSH term(s) Diabetes Complications/genetics ; Diabetes Complications/therapy ; Diabetes Mellitus, Type 1/genetics ; Diabetes Mellitus, Type 1/therapy ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/therapy ; Diabetic Retinopathy/genetics ; Epigenomics/methods ; Genetic Predisposition to Disease ; Humans ; Molecular Targeted Therapy/methods ; Precision Medicine/methods
    Language English
    Publishing date 2017-11-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2299146-3
    ISSN 1744-828X ; 1741-0541
    ISSN (online) 1744-828X
    ISSN 1741-0541
    DOI 10.2217/pme-2017-0043
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6549: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 73: Show issues

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  9. Article: β-Lactoglobulin delivery system for enhancing EGCG biological efficacy in HFD obesity mice model

    Zagury, Yedidya / Chen, Saray / Edelman, Ravit / Karnieli, Eddy / Livney, Yoav D

    Journal of functional foods. 2019 Aug., v. 59

    2019  

    Abstract: Enriching widely-consumed foods and beverages with nutraceuticals is an important disease-prevention strategy. (-)-Epigallocatechin-3-gallate (EGCG), the green-tea polyphenol, is a potent antioxidant with numerous attributed health benefits. However, it ... ...

    Abstract Enriching widely-consumed foods and beverages with nutraceuticals is an important disease-prevention strategy. (-)-Epigallocatechin-3-gallate (EGCG), the green-tea polyphenol, is a potent antioxidant with numerous attributed health benefits. However, it is bitter, astringent, and susceptible to oxidation. Herein we studied our recently developed beta-lactoglobulin (β-Lg)-based delivery system, assessing its efficacy in the prevention of metabolic syndrome effects in a high-fat-diet (HFD)-induced obesity mice model. Metabolic effects were evaluated in mice fed either HFD or normal diet (ND), which concomitantly consumed either milk (1% fat) fortified with EGCG-β-Lg complexes, or free EGCG, or water with EGCG or water only, for 12 weeks. HFD mice receiving EGCG-β-Lg complexes in milk, had significantly lower liver-triglycerides levels compared to control (HFD-water) group. Moreover, compared to free EGCG in milk, EGCG-β-Lg complexes significantly improved glucose tolerance in both diets. Thus, β-Lg delivery system may improve the efficacy of polyphenols like EGCG in preventing the metabolic syndrome.
    Keywords animal models ; antioxidants ; beta-lactoglobulin ; beverages ; dietary supplements ; disease prevention ; epigallocatechin gallate ; glucose tolerance ; green tea ; high fat diet ; lipid content ; metabolic syndrome ; mice ; milk ; obesity ; oxidation ; polyphenols
    Language English
    Dates of publication 2019-08
    Size p. 362-370.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 2511964-3
    ISSN 1756-4646
    ISSN 1756-4646
    DOI 10.1016/j.jff.2019.05.053
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7830: Show issues

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  10. Article ; Online: Preventing type 2 diabetes mellitus: a call for personalized intervention.

    Glauber, Harry / Karnieli, Eddy

    The Permanente journal

    2013  Volume 17, Issue 3, Page(s) 74–79

    Abstract: In parallel with the rising prevalence of obesity worldwide, especially in younger people, there has been a dramatic increase in recent decades in the incidence and prevalence of metabolic consequences of obesity, in particular prediabetes and type 2 ... ...

    Abstract In parallel with the rising prevalence of obesity worldwide, especially in younger people, there has been a dramatic increase in recent decades in the incidence and prevalence of metabolic consequences of obesity, in particular prediabetes and type 2 diabetes mellitus (DM2). Although approximately one-third of US adults now meet one or more diagnostic criteria for prediabetes, only a minority of those so identified as being at risk for DM2 actually progress to diabetes, and some may regress to normal status. Given the uncertain prognosis of prediabetes, it is not clear who is most likely to benefit from lifestyle change or medication interventions that are known to reduce DM2 risk. We review the many factors known to influence risk of developing DM2 and summarize treatment trials demonstrating the possibility of preventing DM2. Applying the concepts of personalized medicine and the potential of "big data" approaches to analysis of massive amounts of routinely gathered clinical and laboratory data from large populations, we call for the development of tools to more precisely estimate individual risk of DM2.
    MeSH term(s) Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/prevention & control ; Humans ; Life Style ; Obesity/complications ; Patient Selection ; Prediabetic State/therapy
    Language English
    Publishing date 2013-10-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2062823-7
    ISSN 1552-5775 ; 1552-5775
    ISSN (online) 1552-5775
    ISSN 1552-5775
    DOI 10.7812/TPP/12-143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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