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Artikel: Hemophagocytic Lymphohistiocytosis: A Rare Complication of COVID-19 in a Patient With Sickle Cell Anemia.

Al-Handola, Rami / Abdelkader, Khaled / Karrar, Arif / Chinnappan, Justine / Rode, Geeta

Cureus

2023  Band 15, Heft 10, Seite(n) e47631

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is an uncommon condition that can be fatal due to overwhelming macrophage activation and cytokine production. It can be primary (familial/genetic) or secondary. It is associated with infections, malignancies, and ... ...

Abstract Hemophagocytic lymphohistiocytosis (HLH) is an uncommon condition that can be fatal due to overwhelming macrophage activation and cytokine production. It can be primary (familial/genetic) or secondary. It is associated with infections, malignancies, and rheumatologic and immunodeficiency disorders. We report a middle-aged female patient with sickle cell anemia who presented with COVID-19 infection that triggered a vaso-occlusive crisis and resulted in HLH. She had preexisting high ferritin levels and cytopenias, making the diagnosis more challenging. A high index of suspicion and timely treatment is essential to prevent adverse outcomes.
Sprache Englisch
Erscheinungsdatum 2023-10-25
Erscheinungsland United States
Dokumenttyp Case Reports
ZDB-ID 2747273-5
ISSN 2168-8184
ISSN 2168-8184
DOI 10.7759/cureus.47631
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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