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  1. Article ; Online: Antimicrobial Activity of Combined Cinnamon Nanoemulsions-Antibiotics against Acinetobacter baumannii

    Dana Khdr Sabir / Karzan R. Sidiq

    Passer Journal, Vol 1, Iss 2, Pp 8-

    2019  Volume 11

    Abstract: Threats of Acinetobacter baumannii, a Gram-negative and multi-drug resistant bacterium,to the public health have recently received great attention worldwide. This is because the high incidence rate of the bacterial infections and the ability of the A. ... ...

    Abstract Threats of Acinetobacter baumannii, a Gram-negative and multi-drug resistant bacterium,to the public health have recently received great attention worldwide. This is because the high incidence rate of the bacterial infections and the ability of the A. baumannii to resist a wide range of antibiotics. This study is designed to investigate the antimicrobial activity of the cinnamon oil in water as Nano emulsions (NEs) alone and in combination with different antibiotics against clinical isolate of A. baumannii. At the beginning, the minimum inhibitory concentration (MIC) of different antibiotics and also cinnamon Nano emulsions (CNEs) are determined. Later, the synergistic effect of the CNEs with each of the studied antibiotics is also examined. Results showed that the bacterium has the highest resistant towards ampicillin (MIC = 700 µg/ml), followed by kanamycin, and gentamycin with MIC of each of the antibiotics was 200µg/ml and 150 µg/ml, respectively. Cinnamon Nano emulsions (CNEs) were also showed a profound inhibitory effect on A. baummanii. Interestingly, combinations of cinnamon Nano emulsions (CNEs) with either kanamycin or gentamycin, but not ampicillin, show a significant increase in the antimicrobial activity of each of the antibiotics compared to when they were used alone. The results of this study strongly suggest the potential application of CNEs in combination with antibiotics to overcome A. baummanii infections.
    Keywords cinnamon nanoemulsions ; multidrug resistance bacteria ; acinetobacter baumannii ; minimum inhibitory concentration ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 540
    Language English
    Publishing date 2019-09-01T00:00:00Z
    Publisher University of Garmian
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Current Speculations on the Low Incidence Rate of the COVID-19 among Children

    Dana Khdr Sabir / Karzan R Sidiq / Shakhawan M Ali

    International Journal of School Health, Vol 7, Iss 2, Pp 61-

    2020  Volume 62

    Abstract: ...

    Abstract .
    Keywords covid-19 ; sars-cov-2 ; children ; immunity ; immunization ; vaccination ; Public aspects of medicine ; RA1-1270 ; covid19
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Shiraz University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Does Early Childhood Vaccination Protect Against COVID-19?

    Karzan R. Sidiq / Dana Khdr Sabir / Shakhawan M. Ali / Rimantas Kodzius

    Frontiers in Molecular Biosciences, Vol

    2020  Volume 7

    Abstract: The coronavirus disease 2019 (COVID-19) is an on-going pandemic caused by the SARS-coronavirus-2 (SARS-CoV-2) which targets the respiratory system of humans. The published data show that children, unlike adults, are less susceptible to contracting the ... ...

    Abstract The coronavirus disease 2019 (COVID-19) is an on-going pandemic caused by the SARS-coronavirus-2 (SARS-CoV-2) which targets the respiratory system of humans. The published data show that children, unlike adults, are less susceptible to contracting the disease. This article aims at understanding why children constitute a minor group among hospitalized COVID-19 patients. Here, we hypothesize that the measles, mumps, and rubella (MMR) vaccine could provide a broad neutralizing antibody against numbers of diseases, including COVID-19. Our hypothesis is based on the 30 amino acid sequence homology between the SARS-CoV-2 Spike (S) glycoprotein (PDB: 6VSB) of both the measles virus fusion (F1) glycoprotein (PDB: 5YXW_B) and the rubella virus envelope (E1) glycoprotein (PDB: 4ADG_A). Computational analysis of the homologous region detected the sequence as antigenic epitopes in both measles and rubella. Therefore, we believe that humoral immunity, created through the MMR vaccination, provides children with advantageous protection against COVID-19 as well, however, an experimental analysis is required.
    Keywords children ; virus ; COVID-19 ; measles ; rubella ; immunity ; Biology (General) ; QH301-705.5 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Factors Contributing to the Containment of the COVID-19 in Kurdistan Region of Iraq

    Dana Khdr Sabir / Karzan R Sidiq / Hadi M Abdullah / Shakhawan M Ali / Nabaz R Khwarahm

    Advanced Journal of Emergency Medicine, Vol 4, Iss 2s (2020)

    2020  

    Abstract: A highly contagious coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which was first identified in Wuhan, China in December 2019. The virus primarily affects the respiratory system of human ... ...

    Abstract A highly contagious coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which was first identified in Wuhan, China in December 2019. The virus primarily affects the respiratory system of human beings and results in the symptoms of headache, fever, dry cough, sore throat, shortness of breath and fatigue with abnormal chest computed tomography (CT) scan. In some cases, nasal sputum discharge and diarrhea have been also reported. Up to the 26th of April 2020, more than three million laboratory confirmed cases of COVID-19 have been recorded worldwide with more than 220,000 confirmed deaths. In the Kurdistan region of Iraq, the first case of laboratory confirmed COVID-19 was recorded in March 1st, 2020 in Sulaymaniyah province.
    Keywords Medicine ; R ; covid19
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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