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  1. Article: Zenker Diverticulum: Does Size Correlate with Preoperative Symptoms?

    Martinez-Paredes, Jhon F / Alfakir, Razan / Kasperbauer, Jan L / Rutt, Amy

    International archives of otorhinolaryngology

    2021  Volume 26, Issue 3, Page(s) e334–e338

    Abstract: ... ...

    Abstract Introduction
    Language English
    Publishing date 2021-10-26
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2578584-9
    ISSN 1809-4864 ; 1809-9777
    ISSN (online) 1809-4864
    ISSN 1809-9777
    DOI 10.1055/s-0041-1730457
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  2. Article ; Online: Asymptomatic right internal carotid artery pseudoaneurysm and Eagle's syndrome.

    Rocco, Raffaele / Bower, Thomas C / Macedo, Thanila A / Kasperbauer, Jan / Morris, Jonathan / Mendes, Bernardo C

    Journal of vascular surgery

    2022  Volume 75, Issue 2, Page(s) 695–696

    MeSH term(s) Aneurysm, False/diagnosis ; Aneurysm, False/etiology ; Aneurysm, False/surgery ; Asymptomatic Diseases ; Blood Vessel Prosthesis Implantation/methods ; Carotid Artery, Internal ; Computed Tomography Angiography/methods ; Femoral Artery/transplantation ; Follow-Up Studies ; Humans ; Imaging, Three-Dimensional ; Male ; Ossification, Heterotopic/complications ; Temporal Bone/abnormalities ; Young Adult
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605700-7
    ISSN 1097-6809 ; 0741-5214
    ISSN (online) 1097-6809
    ISSN 0741-5214
    DOI 10.1016/j.jvs.2021.02.016
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  3. Article: Mandibular Tori Limiting Treatment of Carcinoma of the Upper Aerodigestive Tract.

    Low, Christopher M / Price, Daniel L / Kasperbauer, Jan L

    Clinical medicine insights. Case reports

    2019  Volume 12, Page(s) 1179547619856599

    Abstract: Background: Mandibular tori are a rare cause of difficult direct visualization of the upper aerodigestive tract. In the setting of aerodigestive tract pathology necessitating direct visualization, removal of mandibular tori may be required to facilitate ...

    Abstract Background: Mandibular tori are a rare cause of difficult direct visualization of the upper aerodigestive tract. In the setting of aerodigestive tract pathology necessitating direct visualization, removal of mandibular tori may be required to facilitate treatment.
    Methods: In the first case, large bilateral symmetric mandibular tori were removed to facilitate access to the anterior commissure and removal of a T1 glottic squamous cell carcinoma (SCC). In the second case, large bilateral mandibular tori were removed to access a markedly exophytic SCC in the right vallecula. Subsequently, the tumor was removed with robotic assistance with excellent exposure.
    Results: Both patients were free of recurrence at last follow-up.
    Conclusion: Mandibular tori are an uncommon cause of difficult direct laryngoscopy. In situations that require direct visualization of the anterior commissure or base of tongue for diagnosis and management of lesions, surgical removal of the tori may be required as in the cases presented here.
    Language English
    Publishing date 2019-07-03
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2580498-4
    ISSN 1179-5476
    ISSN 1179-5476
    DOI 10.1177/1179547619856599
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  4. Article ; Online: Acute airway compromise after recombinant human TSH administration: A case report and review of the literature.

    Dowling, Eric / Kasperbauer, Jan / Morris, John / Bayan, Semirra

    The Laryngoscope

    2019  Volume 130, Issue 11, Page(s) 2725–2727

    Abstract: Radioiodine ablation is a commonly utilized treatment for differentiated thyroid carcinoma. Uptake of radioiodine can be enhanced by pretreatment with thyroid hormone withdrawal or administration of recombinant human thyroid-stimulating hormone (rhTSH). ... ...

    Abstract Radioiodine ablation is a commonly utilized treatment for differentiated thyroid carcinoma. Uptake of radioiodine can be enhanced by pretreatment with thyroid hormone withdrawal or administration of recombinant human thyroid-stimulating hormone (rhTSH). rhTSH is generally well-tolerated with minimal adverse effects. However, in patients with extensive tumor burden in confined anatomic spaces, rapid enlargement of normal or neoplastic thyroid tissue secondary to rhTSH administration can result in significant compressive effects. In this report, we describe a case of rapid airway deterioration requiring intubation in a patient with involvement of the thyroid cartilage by papillary thyroid carcinoma. Laryngoscope, 122:0000-0000, 2019 Laryngoscope, 130:2725-2727, 2020.
    MeSH term(s) Acute Disease ; Aged, 80 and over ; Airway Obstruction/chemically induced ; Carcinoma/therapy ; Humans ; Iodine Radioisotopes ; Male ; Medical Illustration ; Radiofrequency Ablation/adverse effects ; Recombinant Proteins/adverse effects ; Thyroid Gland/drug effects ; Thyroid Neoplasms/therapy ; Thyrotropin/adverse effects
    Chemical Substances Iodine Radioisotopes ; Recombinant Proteins ; Thyrotropin (9002-71-5)
    Language English
    Publishing date 2019-12-10
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.28439
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  5. Article ; Online: Endoscopic Wedge Excisions with CO2 Laser for Subglottic Stenosis.

    Ekbom, Dale C / Bayan, Semirra L / Goates, Andrew J / Kasperbauer, Jan L

    The Laryngoscope

    2020  Volume 131, Issue 4, Page(s) E1062–E1066

    MeSH term(s) Female ; Humans ; Laryngoscopy ; Laryngostenosis/surgery ; Laser Therapy/methods ; Lasers, Gas ; Male ; Patient Positioning
    Language English
    Publishing date 2020-08-21
    Publishing country United States
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.29013
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  6. Article ; Online: Cricopharyngeal Myotomy in Inclusion Body Myositis: Comparison of Endoscopic and Transcervical Approaches.

    McMillan, Ryan A / Bowen, Andrew J / Bayan, Semirra L / Kasperbauer, Jan L / Ekbom, Dale C

    The Laryngoscope

    2021  Volume 131, Issue 8, Page(s) E2426–E2431

    Abstract: Objective: Inclusion body myositis (IBM) is a progressive inflammatory myopathy with dysphagia as a debilitating sequalae. Otolaryngologists are consulted for surgical candidacy when there are findings of cricopharyngeal dysfunction. We aim to compare ... ...

    Abstract Objective: Inclusion body myositis (IBM) is a progressive inflammatory myopathy with dysphagia as a debilitating sequalae. Otolaryngologists are consulted for surgical candidacy when there are findings of cricopharyngeal dysfunction. We aim to compare transcervical cricopharyngeal myotomy (TCPM) versus endoscopic cricopharyngeal myotomy (ECPM) in the IBM population with particular focus on objective swallow study outcomes, complications, and recurrence rates.
    Methods: A retrospective cohort study was performed on IBM patients who underwent TCPM or ECPM (1981-2020) in the Department of Otolaryngology at a tertiary academic center with a high volume IBM referral base. Videofluoroscopic swallow studies, Eating Assessment Tool (EAT-10), Reflux Symptom Index (RSI), and Functional Outcome Swallowing Scale (FOSS) were collected at preoperative and follow-up visits. Baseline patient characteristics, intraoperative data, and postoperative course were recorded.
    Results: Forty-one patients were identified (18 TCPM; 23 ECPM). There was no significant difference in the recurrence rates, complications, hospitalization length, operative time, or return to preoperative diet between approaches. For the 12 patients (11 ECPM; 1 TCPM) that had subjective swallow data, there was a statistically significant difference in the pre and postoperative scores for EAT-10, RSI, and FOSS (P < .05). There was a statistically significant improvement in the degree of narrowing between pre and postoperative imaging for both approaches (P < .05).
    Conclusion: Both TCPM and ECPM are safe approaches for the management of dysphagia in patients with IBM with objective evidence of cricopharyngeal dysfunction. Cricopharyngeal myotomy is a durable technique that has demonstrated improved subjective and objective outcomes in this patient population.
    Level of evidence: 3 Laryngoscope, 131:E2426-E2431, 2021.
    MeSH term(s) Aged ; Aged, 80 and over ; Deglutition/physiology ; Deglutition Disorders/etiology ; Deglutition Disorders/surgery ; Endoscopy/methods ; Endoscopy/statistics & numerical data ; Esophageal Sphincter, Upper/physiopathology ; Esophageal Sphincter, Upper/surgery ; Female ; Follow-Up Studies ; Hospitalization/statistics & numerical data ; Humans ; Male ; Middle Aged ; Myositis, Inclusion Body/complications ; Myositis, Inclusion Body/diagnosis ; Myositis, Inclusion Body/pathology ; Myotomy/adverse effects ; Myotomy/methods ; Myotomy/statistics & numerical data ; Neck/surgery ; Operative Time ; Postoperative Complications/epidemiology ; Recurrence ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-02-12
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.29444
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  7. Article: Zenker Diverticulum: Does Size Correlate with Preoperative Symptoms?

    Martinez-Paredes, Jhon F. / Alfakir, Razan / Kasperbauer, Jan L. / Rutt, Amy

    International Archives of Otorhinolaryngology

    2021  Volume 26, Issue 03, Page(s) e334–e338

    Abstract: Introduction: Zenker diverticulum (ZD) usually affects adults after the 7 th decade of life. Treatment for ZD is indicated for all symptomatic patients, but some patients prefer to defer surgical treatment until symptoms get worse and decrease their ... ...

    Abstract Introduction: Zenker diverticulum (ZD) usually affects adults after the 7 th decade of life. Treatment for ZD is indicated for all symptomatic patients, but some patients prefer to defer surgical treatment until symptoms get worse and decrease their quality of life.
    Objective: To evaluate the association of the preoperative symptoms in ZD patients with the size of the ZD.
    Methods: A retrospective study design. Electronic medical records were used to identify patients diagnosed with ZD and treated over 11 years. Data collection included the chief complaints and symptoms, medical history, and findings on radiologic swallow evaluations of the patients. The diverticulum size was stratified into 3 groups: small (< 1 cm), moderate (1–3 cm), and large (> 3 cm).
    Results: A total of 165 patients were enrolled and stratified by diverticulum size (48 small, 67 medium, and 50 large). Dysphagia, cough, and regurgitation were the most prevalent symptoms. Dysphonia was more frequent among patients with a small pouch. Logistic regression analysis showed that dysphagia and choking were associated with large and medium diverticulum size ( p <  0.05. Additionally, dysphonia was significantly associated with the presence of a small-sized ZD ( p <  0.04).
    Conclusion: Upper gastrointestinal symptoms such as dysphagia and choking may be associated with a ZD > 1 cm and should always be evaluated. Additionally, the presence of dysphonia was found to be correlated with a ZD < 1 cm, suggesting that a prompt and appropriate fluoroscopic evaluation must be considered in those patients in whom no other clear cause of dysphonia is evident.
    Keywords zenker diverticulum ; pharyngeal pouch ; esophageal diverticulum ; dysphagia ; dysphonia
    Language English
    Publishing date 2021-10-26
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2578584-9
    ISSN 1809-4864 ; 1809-9777 ; 1809-4864
    ISSN (online) 1809-4864
    ISSN 1809-9777 ; 1809-4864
    DOI 10.1055/s-0041-1730457
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  8. Article ; Online: Safety outcomes and patient convenience in outpatient parotidectomy.

    Karp, Emily E / Yin, Linda X / Xie, Katherine Z / O'Byrne, Thomas J / Wallerius, Katherine P / Tasche, Kendall K / Van Abel, Kathryn M / Kasperbauer, Jan L / Moore, Eric J / Price, Daniel L

    American journal of otolaryngology

    2023  Volume 44, Issue 2, Page(s) 103806

    Abstract: Background: Parotidectomies have historically been performed on an inpatient basis despite being well-tolerated surgeries with minimal postoperative wound care and low rates of complications at high-volume institutions. Past studies have supported the ... ...

    Abstract Background: Parotidectomies have historically been performed on an inpatient basis despite being well-tolerated surgeries with minimal postoperative wound care and low rates of complications at high-volume institutions. Past studies have supported the safety of outpatient surgery for parotidectomy but have been limited to superficial parotidectomy and have not addressed the patient experience surrounding the surgical intervention such as pre-operative and post-operative care and communication.
    Purpose: This study assesses the impact of outpatient superficial, deep, and partial parotid surgery on various parameters including surgical safety, distance traveled for care, utilization of telehealth, and patient-initiated communication.
    Materials and methods: Retrospective study from January 2020 to October 2021. Patients undergoing superficial lobe, deep lobe, and partial parotidectomies for benign and malignant pathologies were divided into inpatient and outpatient cohorts. A multivariable model examined the relationship between admission status and surgical complications, adjusted for age, sex, and tumor size.
    Results: 159 patients total, 94 outpatient and 65 inpatients. No statistical difference in rates of surgical complications with the exception of salivary leak. There was an increased rate of salivary leak reported in the inpatient group (OR 5.4, 95 % CI 1.6 to 18.0, p = 0.01). Mean patient travel distance of 354 miles one-way. Post-operatively, 76 % were evaluated via video visit. Following discharge, >55 % of patients initiated communication with the surgical team, which was not statistically different between the groups.
    Conclusions: Outpatient parotidectomy is safe and can be more convenient, but telehealth communication must be balanced with rigorous attention to patient education.
    MeSH term(s) Humans ; Parotid Neoplasms/surgery ; Parotid Neoplasms/pathology ; Outpatients ; Retrospective Studies ; Postoperative Complications/epidemiology ; Postoperative Complications/pathology ; Salivary Glands/pathology ; Parotid Gland/surgery ; Parotid Gland/pathology
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.103806
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  9. Article ; Online: Diagnosis and Management of Anaplastic Thyroid Cancer.

    Chintakuntlawar, Ashish V / Foote, Robert L / Kasperbauer, Jan L / Bible, Keith C

    Endocrinology and metabolism clinics of North America

    2018  Volume 48, Issue 1, Page(s) 269–284

    Abstract: Anaplastic thyroid cancer (ATC) is a devastating and usually incurable diagnosis. Clinical and pathologic diagnosis is best assessed at a tertiary center with concentrated ATC expertise. Expeditious multidisciplinary management is recommended for optimal ...

    Abstract Anaplastic thyroid cancer (ATC) is a devastating and usually incurable diagnosis. Clinical and pathologic diagnosis is best assessed at a tertiary center with concentrated ATC expertise. Expeditious multidisciplinary management is recommended for optimal patient outcomes. Based on multiinstitutional and population-based studies, multimodal therapy that includes chemoradiotherapy with surgery (when feasible) is the preferred initial treatment because it is associated with incrementally improved overall survival. In ATC that carries a BRAF V600E somatic mutation, combination therapy with BRAF and MEK inhibitors has shown promise but needs further study. Immunotherapeutic agents in neoadjuvant and metastatic settings are being investigated.
    MeSH term(s) Humans ; Thyroid Carcinoma, Anaplastic/diagnosis ; Thyroid Carcinoma, Anaplastic/therapy ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/therapy
    Language English
    Publishing date 2018-12-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 92116-6
    ISSN 1558-4410 ; 0889-8529
    ISSN (online) 1558-4410
    ISSN 0889-8529
    DOI 10.1016/j.ecl.2018.10.010
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  10. Article ; Online: In Response to Regarding Cricopharyngeal Myotomy in IBM: Comparison of Endoscopic and Transcervical Approaches.

    McMillan, Ryan A / Bowen, Andrew J / Crum, Brian A / Bayan, Semirra L / Kasperbauer, Jan L / Ekbom, Dale C

    The Laryngoscope

    2021  Volume 131, Issue 6, Page(s) E1999

    MeSH term(s) Cricoid Cartilage/surgery ; Endoscopy ; Humans ; Myositis, Inclusion Body ; Myotomy ; Pharyngeal Muscles/surgery
    Language English
    Publishing date 2021-04-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.29544
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