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Article ; Online: Intrathoracic Needle Migration from the Mediastinum into the Thoracic Cavity.

Sato, Tomo / Kato, Yasufumi / Kataba, Hiroaki / Yoshida, Koichi / Hayashi, Hiroki / Kakihana, Masatoshi / Ikeda, Norihiko

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia

2024 Volume 30, Issue 1

Abstract: Intrathoracic needles are rarely used in clinical practice. They can migrate within the body, injure large blood vessels and other organs, and cause severe complications. We report an interesting case of intrathoracic needle removal using video-assisted ... ...

Abstract	Intrathoracic needles are rarely used in clinical practice. They can migrate within the body, injure large blood vessels and other organs, and cause severe complications. We report an interesting case of intrathoracic needle removal using video-assisted thoracoscopic surgery. The needle was inserted under the left clavicle, penetrated the mediastinum, and migrated into the right thoracic cavity. Although pneumothorax developed during the disease course, no severe complications were observed. This rare case illustrates the course of needle migration from the mediastinum into the thoracic cavity. Prompt imaging and surgical removal of foreign bodies are necessary in cases of intrathoracic foreign bodies.
MeSH term(s)	Humans ; Mediastinum ; Treatment Outcome ; Thoracic Cavity/surgery ; Foreign Bodies/surgery ; Thoracic Surgery, Video-Assisted/methods ; Foreign-Body Migration/surgery
Language	English
Publishing date	2024-04-16
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2019756-1
ISSN	2186-1005 ; 1341-1098
ISSN (online)	2186-1005
ISSN	1341-1098
DOI	10.5761/atcs.cr.24-00039
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Article ; Online: Correction to: Successful adjustment for self-expanding metallic stent migration using a flexible bronchoscope with two biopsy forceps technique.

Yoneyama, Remi / Saji, Hisashi / Makino, Yojiro / Kato, Yasufumi / Kajiwara, Naohiro / Ohira, Tatsuo / Ikeda, Norihiko

General thoracic and cardiovascular surgery

2019 Volume 67, Issue 9, Page(s) 821

Abstract: In the original publication of the article, the corresponding author email address was published wrongly. ...

Abstract	In the original publication of the article, the corresponding author email address was published wrongly.
Language	English
Publishing date	2019-06-18
Publishing country	Japan
Document type	Journal Article ; Published Erratum
ZDB-ID	2376888-5
ISSN	1863-6713 ; 1863-6705
ISSN (online)	1863-6713
ISSN	1863-6705
DOI	10.1007/s11748-019-01167-7
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Article: OAT10/SLC22A13 Acts as a Renal Urate Re-Absorber: Clinico-Genetic and Functional Analyses With Pharmacological Impacts.

Toyoda, Yu / Kawamura, Yusuke / Nakayama, Akiyoshi / Morimoto, Keito / Shimizu, Seiko / Tanahashi, Yuki / Tamura, Takashi / Kondo, Takaaki / Kato, Yasufumi / Ichida, Kimiyoshi / Suzuki, Hiroshi / Shinomiya, Nariyoshi / Kobayashi, Yasushi / Takada, Tappei / Matsuo, Hirotaka

Frontiers in pharmacology

2022 Volume 13, Page(s) 842717

Abstract: Dysfunctional missense variant ... ...

Abstract	Dysfunctional missense variant of
Language	English
Publishing date	2022-04-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2022.842717
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Article ; Online: Cost-Benefit Performance Simulation of Robot-Assisted Thoracic Surgery As Required for Financial Viability under the 2016 Revised Reimbursement Paradigm of the Japanese National Health Insurance System.

Kajiwara, Naohiro / Kato, Yasufumi / Hagiwara, Masaru / Kakihana, Masatoshi / Ohira, Tatsuo / Kawate, Norihiko / Ikeda, Norihiko

Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia

2018 Volume 24, Issue 2, Page(s) 73–80

Abstract: Purpose: To discuss the cost-benefit performance (CBP) and establish a medical fee system for robotic-assisted thoracic surgery (RATS) under the Japanese National Health Insurance System (JNHIS), which is a system not yet firmly established.: Methods!# ...

Abstract	Purpose: To discuss the cost-benefit performance (CBP) and establish a medical fee system for robotic-assisted thoracic surgery (RATS) under the Japanese National Health Insurance System (JNHIS), which is a system not yet firmly established. Methods: All management steps for RATS are identical, such as preoperative and postoperative management. This study examines the CBP based on medical fees of RATS under the JNHIS introduced in 2016. Results: Robotic-assisted laparoscopic prostatectomy (RALP) and robotic-assisted partial nephrectomy (RAPN) now receive insurance reimbursement under the category of use of support devices for endoscopic surgery ($5420 and $3485, respectively). If the same standard amount were to be applied to RATS, institutions would need to perform at least 150 or 300 procedures thoracic operation per year to show a positive CBP ($317 per procedure as same of RALP and $130 per procedure as same of RAPN, respectively). Conclusion: Robotic surgery in some areas receives insurance reimbursement for its "supportive" use for endoscopic surgery as for RALP and RAPN. However, at present, it is necessary to perform da Vinci Surgical System Si (dVSi) surgery at least 150-300 times in a year in a given institution to prevent a deficit in income.
MeSH term(s)	Computer Simulation ; Cost-Benefit Analysis ; Health Care Costs ; Humans ; Insurance, Health, Reimbursement/economics ; Japan ; Models, Economic ; National Health Programs/economics ; Process Assessment (Health Care)/economics ; Robotic Surgical Procedures/economics ; Robotic Surgical Procedures/methods ; Thoracic Surgical Procedures/economics ; Thoracic Surgical Procedures/methods
Language	English
Publishing date	2018-01-17
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2019756-1
ISSN	2186-1005 ; 1341-1098
ISSN (online)	2186-1005
ISSN	1341-1098
DOI	10.5761/atcs.oa.17-00094
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Article ; Online: Association between consumption of small fish and all-cause mortality among Japanese: the Japan Multi-Institutional Collaborative Cohort Study.

Kasahara, Chinatsu / Tamura, Takashi / Wakai, Kenji / Tamada, Yudai / Kato, Yasufumi / Kubo, Yoko / Okada, Rieko / Nagayoshi, Mako / Hishida, Asahi / Imaeda, Nahomi / Goto, Chiho / Otonari, Jun / Ikezaki, Hiroaki / Nishida, Yuichiro / Shimanoe, Chisato / Oze, Isao / Koyanagi, Yuriko N / Nakamura, Yohko / Kusakabe, Miho /

Nishimoto, Daisaku / Shimoshikiryo, Ippei / Suzuki, Sadao / Watanabe, Miki / Ozaki, Etsuko / Omichi, Chie / Kuriki, Kiyonori / Takashima, Naoyuki / Miyagawa, Naoko / Arisawa, Kokichi / Katsuura-Kamano, Sakurako / Takeuchi, Kenji / Matsuo, Keitaro

Public health nutrition

2024 , Page(s) 1–40

Abstract: Objective: Although small fish are an important source of micronutrients, the relationship between their intake and mortality remains unclear. This study aimed to clarify the association between intake of small fish and all-cause and cause-specific ... ...

Abstract	Objective: Although small fish are an important source of micronutrients, the relationship between their intake and mortality remains unclear. This study aimed to clarify the association between intake of small fish and all-cause and cause-specific mortality. Design: We used the data from a cohort study in Japan. The frequency of the intake of small fish was assessed using a validated food frequency questionnaire. The hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause and cause-specific mortality according to the frequency of the intake of small fish by sex were estimated using a Cox proportional hazard model with adjustments for covariates. Setting: The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study. Participants: A total of 80,802 participants (34,555 males and 46,247 females), aged 35-69 years. Results: During a mean follow-up of 9.0 years, we identified 2,482 deaths including 1,495 cancer-related deaths. The intake of small fish was statistically significantly and inversely associated with the risk of all-cause and cancer mortality in females. The multivariable-adjusted HRs (95% CIs) in females for all-cause mortality according to the intake were 0.68 (0.55-0.85) for intakes 1-3 times/month, 0.72 (0.57-0.90) for 1-2 times/week, and 0.69 (0.54-0.88) for ≥3 times/week, compared with the rare intake. The corresponding HRs (95% CIs) in females for cancer mortality were 0.72 (0.54-0.96), 0.71 (0.53-0.96), and 0.64 (0.46-0.89), respectively. No statistically significant association was observed in males. Conclusions: Intake of small fish may reduce the risk of all-cause and cancer mortality in Japanese females.
Language	English
Publishing date	2024-05-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1436024-x
ISSN	1475-2727 ; 1368-9800
ISSN (online)	1475-2727
ISSN	1368-9800
DOI	10.1017/S1368980024000831
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Article ; Online: Successful adjustment for self-expanding metallic stent migration using a flexible bronchoscope with two biopsy forceps technique.

Yoneyama, Remi / Saji, Hisashi / Makino, Yojiro / Kato, Yasufumi / Kajiwara, Naohiro / Ohira, Tatsuo / Ikeda, Norihiko

General thoracic and cardiovascular surgery

2017 Volume 65, Issue 12, Page(s) 720–723

Abstract: Although tracheobronchial stents are widely used for tracheal obstruction due to malignant or benign stenosis, stent migration has been reported as a major postoperative complication. A self-expandable metallic stent (SEMS) is more easily introduced ... ...

Abstract	Although tracheobronchial stents are widely used for tracheal obstruction due to malignant or benign stenosis, stent migration has been reported as a major postoperative complication. A self-expandable metallic stent (SEMS) is more easily introduced compared with silicone stents. However, it is also difficult to remove or replace without complications. We report a new technique for successful SEMS adjustment using a flexible bronchoscope with two biopsy forceps.
MeSH term(s)	Aged ; Airway Obstruction/diagnosis ; Airway Obstruction/etiology ; Airway Obstruction/surgery ; Biopsy/instrumentation ; Bronchoscopes ; Carcinoma, Squamous Cell/diagnosis ; Carcinoma, Squamous Cell/surgery ; Female ; Foreign-Body Migration/complications ; Foreign-Body Migration/diagnosis ; Foreign-Body Migration/surgery ; Humans ; Mediastinal Neoplasms/diagnosis ; Mediastinal Neoplasms/surgery ; Prosthesis Failure ; Self Expandable Metallic Stents/adverse effects ; Surgical Instruments ; Trachea/injuries
Language	English
Publishing date	2017-03-02
Publishing country	Japan
Document type	Case Reports ; Journal Article
ZDB-ID	2376888-5
ISSN	1863-6713 ; 1863-6705
ISSN (online)	1863-6713
ISSN	1863-6705
DOI	10.1007/s11748-017-0762-4
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Article ; Online: Association between awareness of limiting food intake and all-cause mortality: A cohort study in Japan.

Nishimoto, Daisaku / Ibusuki, Rie / Shimoshikiryo, Ippei / Shibuya, Kenichi / Tanoue, Shiroh / Koriyama, Chihaya / Takezaki, Toshiro / Oze, Isao / Ito, Hidemi / Hishida, Asahi / Tamura, Takashi / Kato, Yasufumi / Tamada, Yudai / Nishida, Yuichiro / Shimanoe, Chisato / Suzuki, Sadao / Nishiyama, Takeshi / Ozaki, Etsuko / Tomida, Satomi /

Kuriki, Kiyonori / Miyagawa, Naoko / Kondo, Keiko / Arisawa, Kokichi / Watanabe, Takeshi / Ikezaki, Hiroaki / Otonari, Jun / Wakai, Kenji / Matsuo, Keitaro

Journal of epidemiology

2023

Abstract: Background: Improving diets requires an awareness of the need to limit foods for which excessive consumption is a health problem. Since there are limited reports on the link between this awareness and mortality risk, we examined the association between ... ...

Abstract	Background: Improving diets requires an awareness of the need to limit foods for which excessive consumption is a health problem. Since there are limited reports on the link between this awareness and mortality risk, we examined the association between awareness of limiting food intake (energy, fat, and sweets) and all-cause mortality in a Japanese cohort study. Methods: Participants comprised 58,772 residents (27,294 men; 31,478 women) aged 35-69 years who completed baseline surveys of the Japan Multi-Institutional Collaborative Cohort Study from 2004 to 2014. Hazard ratios (HRs) for all-cause mortality and 95% confidence intervals (CIs) were estimated by sex using a Cox proportional hazard model, with adjustment for related factors. Mediation analysis with fat intake as a mediator was also conducted. Results: The mean follow-up period was 11 years and 2,516 people died. Estimated energy and fat intakes according to the Food Frequency Questionnaire were lower in those with awareness of limiting food intake than in those without this awareness. Women with awareness of limiting fat intake showed a significant decrease in mortality risk (HR=0.73; 95% CI, 0.55 to 0.94). Mediation analysis revealed that this association was due to the direct effect of the awareness of limiting fat intake and that the total effect was not mediated by actual fat intake. Awareness of limiting energy or sweets intake was not related to mortality risk reduction. Conclusion: Awareness of limiting food intake had a limited effect on reducing all-cause mortality risk.
Language	English
Publishing date	2023-11-04
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1442118-5
ISSN	1349-9092 ; 0917-5040
ISSN (online)	1349-9092
ISSN	0917-5040
DOI	10.2188/jea.JE20220354
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Article ; Online: Coffee and metabolic phenotypes: A cross-sectional analysis of the Japan multi-institutional collaborative cohort (J-MICC) study.

Nutrition, metabolism, and cardiovascular diseases : NMCD

2022 Volume 33, Issue 3, Page(s) 620–630

Abstract: Background and aims: To date, the relationship between coffee consumption and metabolic phenotypes has hardly been investigated and remains controversial. Therefore, the aim of this cross-sectional study is to examine the associations between coffee ... ...

Abstract	Background and aims: To date, the relationship between coffee consumption and metabolic phenotypes has hardly been investigated and remains controversial. Therefore, the aim of this cross-sectional study is to examine the associations between coffee consumption and metabolic phenotypes in a Japanese population. Methods and results: We analyzed the data of 26,363 subjects (aged 35-69 years) in the baseline survey of the Japan Multi-Institutional Collaborative Cohort Study. Coffee consumption was assessed using a questionnaire. Metabolic Syndrome (MetS) was defined according to the Joint Interim Statement Criteria of 2009, using body mass index (BMI) instead of waist circumference. Subjects stratified by the presence or absence of obesity (normal weight: BMI <25 kg/m Conclusion: The present results suggest that high coffee consumption, particularly filtered/instant coffee, is inversely associated with the prevalence of metabolically unhealthy phenotypes in both normal weight and obese Japanese adults.
MeSH term(s)	Humans ; Cross-Sectional Studies ; Coffee/adverse effects ; Cohort Studies ; Japan/epidemiology ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/epidemiology ; Metabolic Syndrome/prevention & control ; Obesity/diagnosis ; Obesity/epidemiology ; Obesity/metabolism ; Body Mass Index ; Phenotype ; Risk Factors
Chemical Substances	Coffee
Language	English
Publishing date	2022-12-29
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1067704-5
ISSN	1590-3729 ; 0939-4753
ISSN (online)	1590-3729
ISSN	0939-4753
DOI	10.1016/j.numecd.2022.12.019
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Article ; Online: A proteogenomic profile of early lung adenocarcinomas by protein co-expression network and genomic alteration analysis.

Nishimura, Toshihide / Nakamura, Haruhiko / Tan, Kien Thiam / Zhuo, De-Wei / Fujii, Kiyonaga / Koizumi, Hirotaka / Naruki, Saeko / Takagi, Masayuki / Furuya, Naoki / Kato, Yasufumi / Chen, Shu-Jen / Kato, Harubumi / Saji, Hisashi

Scientific reports

2020 Volume 10, Issue 1, Page(s) 13604

Abstract: The tumourigenesis of early lung adenocarcinomas, including adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and lepidic predominant invasive adenocarcinoma (LPA), remains unclear. This study aimed to capture disease-related ... ...

Abstract	The tumourigenesis of early lung adenocarcinomas, including adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and lepidic predominant invasive adenocarcinoma (LPA), remains unclear. This study aimed to capture disease-related molecular networks characterising each subtype and tumorigenesis by assessing 14 lung adenocarcinomas (AIS, five; MIA, five; LPA, four). Protein-protein interaction networks significant to the three subtypes were elucidated by weighted gene co-expression network analysis and pairwise G-statistics based analysis. Pathway enrichment analysis for AIS involved extracellular matrix proteoglycans and neutrophil degranulation pathway relating to tumour growth and angiogenesis. Whereas no direct networks were found for MIA, proteins significant to MIA were involved in oncogenic transformation, epithelial-mesenchymal transition, and detoxification in the lung. LPA was associated with pathways of HSF1-mediated heat shock response regulation, DNA damage repair, cell cycle regulation, and mitosis. Genomic alteration analysis suggested that LPA had both somatic mutations with loss of function and copy number gains more frequent than MIA. Oncogenic drivers were detected in both MIA and LPA, and also LPA had a higher degree of copy number loss than MIA. Our findings may help identifying potential therapeutic targets and developing therapeutic strategies to improve patient outcomes.
MeSH term(s)	Adenocarcinoma in Situ/genetics ; Adenocarcinoma in Situ/metabolism ; Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/metabolism ; Epithelial-Mesenchymal Transition ; Female ; Gene Dosage ; Gene Regulatory Networks ; Humans ; Loss of Function Mutation ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Male ; Middle Aged ; Neoplasm Invasiveness ; Protein Interaction Maps ; Proteogenomics/methods
Language	English
Publishing date	2020-08-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-70578-x
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Article ; Online: GWAS of Folate Metabolism With Gene-environment Interaction Analysis Revealed the Possible Role of Lifestyles in the Control of Blood Folate Metabolites in Japanese: The J-MICC Study.

Tsukamoto, Mineko / Hishida, Asahi / Tamura, Takashi / Nagayoshi, Mako / Okada, Rieko / Kubo, Yoko / Kato, Yasufumi / Hamajima, Nobuyuki / Nishida, Yuichiro / Shimanoe, Chisato / Ibusuki, Rie / Shibuya, Kenichi / Takashima, Naoyuki / Nakamura, Yasuyuki / Kusakabe, Miho / Nakamura, Yohko / Koyanagi, Yuriko N / Oze, Isao / Nishiyama, Takeshi /

Suzuki, Sadao / Watanabe, Isao / Matsui, Daisuke / Otonari, Jun / Ikezaki, Hiroaki / Katsuura-Kamano, Sakurako / Arisawa, Kokichi / Kuriki, Kiyonori / Nakatochi, Masahiro / Momozawa, Yukihide / Takeuchi, Kenji / Wakai, Kenji / Matsuo, Keitaro

Journal of epidemiology

2023 Volume 34, Issue 5, Page(s) 228–237

Abstract: Background: The present genome-wide association study (GWAS) aimed to reveal the genetic loci associated with folate metabolites, as well as to detect related gene-environment interactions in Japanese.: Methods: We conducted the GWAS of plasma ... ...

Abstract	Background: The present genome-wide association study (GWAS) aimed to reveal the genetic loci associated with folate metabolites, as well as to detect related gene-environment interactions in Japanese. Methods: We conducted the GWAS of plasma homocysteine (Hcy), folic acid (FA), and vitamin B Results: For Hcy, MTHFR locus on chr 1, NOX4 on chr 11, CHMP1A on chr 16, and DPEP1 on chr 16 reached genome-wide significance (P < 5 × 10 Conclusion: The present GWAS revealed the folate metabolism-associated genetic loci and gene-environment interactions with drinking and physical activity in Japanese, suggesting the possibility of future personalized cardiovascular disease prevention.
MeSH term(s)	Humans ; Folic Acid/blood ; Japan ; Genome-Wide Association Study ; Gene-Environment Interaction ; Male ; Female ; Middle Aged ; Homocysteine/blood ; Life Style ; Adult ; Aged ; Methylenetetrahydrofolate Reductase (NADPH2)/genetics ; Vitamin B 12/blood ; Cohort Studies ; Polymorphism, Single Nucleotide ; East Asian People
Chemical Substances	Folic Acid (935E97BOY8) ; Homocysteine (0LVT1QZ0BA) ; Methylenetetrahydrofolate Reductase (NADPH2) (EC 1.5.1.20) ; Vitamin B 12 (P6YC3EG204) ; MTHFR protein, human (EC 1.5.1.20)
Language	English
Publishing date	2023-12-28
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1442118-5
ISSN	1349-9092 ; 0917-5040
ISSN (online)	1349-9092
ISSN	0917-5040
DOI	10.2188/jea.JE20220341
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