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  1. Article ; Online: Vaccine development against tuberculosis before and after Covid-19.

    Kaufmann, Stefan H E

    Frontiers in immunology

    2023  Volume 14, Page(s) 1273938

    Abstract: Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious diseases on global health. It has also provided instructive lessons for better prevention strategies against new and current infectious diseases of major importance. ...

    Abstract Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious diseases on global health. It has also provided instructive lessons for better prevention strategies against new and current infectious diseases of major importance. Tuberculosis (TB) is a major current health threat caused by
    MeSH term(s) Humans ; COVID-19 Vaccines ; COVID-19/prevention & control ; Tuberculosis/prevention & control ; Tuberculosis Vaccines ; Communicable Diseases ; Vaccine Development
    Chemical Substances COVID-19 Vaccines ; Tuberculosis Vaccines
    Language English
    Publishing date 2023-11-15
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1273938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Lydia Rabinowitsch-Kempner, a TB researcher and role model.

    Kaufmann, Stefan H E

    Nature reviews. Immunology

    2022  Volume 22, Issue 8, Page(s) 464

    Language English
    Publishing date 2022-06-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2062776-2
    ISSN 1474-1741 ; 1474-1733
    ISSN (online) 1474-1741
    ISSN 1474-1733
    DOI 10.1038/s41577-022-00754-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5565: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 34: Show issues

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  3. Book ; Online ; E-Book: Impfen

    Kaufmann, Stefan H. E.

    Grundlagen, Wirkung, Risiken

    (C.H. Beck Wissen ; 2925)

    2021  

    Abstract: Krankheitserreger sind unberechenbare Gegner. Die größte Hoffnung, sie einzuhegen, ruht auf den Impfungen. Von der Veröffentlichung des Erbguts des neuen Corona-Virus bis zur Bereitstellung einsatzbereiter Impfstoffe hat es kaum ein Jahr gebraucht - ... ...

    Author's details Stefan H. E. Kaufmann
    Series title C.H. Beck Wissen ; 2925
    Abstract Krankheitserreger sind unberechenbare Gegner. Die größte Hoffnung, sie einzuhegen, ruht auf den Impfungen. Von der Veröffentlichung des Erbguts des neuen Corona-Virus bis zur Bereitstellung einsatzbereiter Impfstoffe hat es kaum ein Jahr gebraucht - schon jetzt eine der größten Erfolgsgeschichten der Medizin. Der international renommierte Immunologe Stefan Kaufmann, selbst Entwickler eines Impfstoffs gegen Tuberkulose, schlägt den Bogen von der Geburtsstunde der Impfung vor mehr als 200 Jahren über die Ausrottung der Pocken bis zu neuesten Ansätzen für Impfstoffe gegen Krebs und setzt sich auch mit Impfrisiken und Impfgegnern auseinander.
    Language German
    Size 1 Online-Ressource (144 Seiten), Illustrationen
    Edition Originalausgabe
    Publisher C.H. Beck
    Publishing place München
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020997498
    ISBN 978-3-406-77165-1 ; 978-3-406-77164-4 ; 9783406771446 ; 3-406-77165-3 ; 3-406-77164-5 ; 3406771440
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: COVID-19 und die Bedrohungen durch Pandemien

    Kaufmann, Stefan H. E.

    wie sie entstehen und was wir dagegen tun müssen

    (Schriftenreihe Nachhaltigkeit ; 8)

    2021  

    Author's details Stefan H.E. Kaufmann
    Series title Schriftenreihe Nachhaltigkeit ; 8
    Collection
    Keywords Impfung ; Pandemien ; COVID-19
    Language German
    Size 84 Seiten, Illustrationen, 21 cm, 140 g
    Publisher Hessische Landeszentrale für politische Bildung
    Publishing place Wiesbaden
    Publishing country Germany
    Document type Book
    HBZ-ID HT020960179
    ISBN 978-3-943192-56-8 ; 3-943192-56-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 A 442 available for loan (reading room) Lesesaal EG

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  5. Article: Vaccine Development Against Tuberculosis Over the Last 140 Years: Failure as Part of Success.

    Kaufmann, Stefan H E

    Frontiers in microbiology

    2021  Volume 12, Page(s) 750124

    Abstract: The year 2020 was shaped by the COVID-19 pandemic which killed more people than any other infectious disease in this particular year. At the same time, the development of highly efficacious COVID-19 vaccines within less than a year raises hope that this ... ...

    Abstract The year 2020 was shaped by the COVID-19 pandemic which killed more people than any other infectious disease in this particular year. At the same time, the development of highly efficacious COVID-19 vaccines within less than a year raises hope that this threat can be tamed in the near future. For the last 200 years, the agent of tuberculosis (TB) has been the worst killer amongst all pathogens. Although a vaccine has been available for 100 years, TB remains a substantial threat. The TB vaccine, Bacille Calmette-Guérin (BCG), has saved tens of millions of lives since its deployment. It was the best and only choice available amongst many attempts to develop efficacious vaccines and all competitors, be they subunit vaccines, viable vaccines or killed whole cell vaccines have failed. Yet, BCG is insufficient. The last decades have witnessed a reawakening of novel vaccine approaches based on deeper insights into immunity underlying TB and BCG immunization. In addition, technical advances in molecular genetics and the design of viral vectors and adjuvants have facilitated TB vaccine development. This treatise discusses firstly early TB vaccine developments leading to BCG as the sole preventive measure which stood the test of time, but failed to significantly contribute to TB control and secondly more recent attempts to develop novel vaccines are described that focus on the genetically modified BCG-based vaccine VPM1002, which has become the frontrunner amongst viable TB vaccine candidates. It is hoped that highly efficacious vaccines against TB will become available even though it remains unclear whether and when this ambition can be accomplished. None the less it is clear that the goal of reducing TB morbidity and mortality by 90% or 95%, respectively, by 2030 as proposed by the World Health Organization depends significantly on better vaccines.
    Language English
    Publishing date 2021-10-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2021.750124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology.

    Kaufmann, Stefan H E

    Frontiers in immunology

    2020  Volume 11, Page(s) 316

    Abstract: Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines are urgently needed. This treatise describes first the basic ... ...

    Abstract Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines are urgently needed. This treatise describes first the basic immunology and pathology of TB with an emphasis on the role of T lymphocytes. Better understanding of the immune response to
    MeSH term(s) Allergy and Immunology ; BCG Vaccine/immunology ; Clinical Trials as Topic ; Humans ; Molecular Biology ; Tuberculosis/immunology ; Tuberculosis Vaccines/immunology ; Vaccination ; Vaccines, Subunit/immunology ; Vaccines, Synthetic/immunology
    Chemical Substances BCG Vaccine ; Tuberculosis Vaccines ; Vaccines, Subunit ; Vaccines, Synthetic
    Language English
    Publishing date 2020-02-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2020.00316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Novel vaccination strategies

    Kaufmann, Stefan H. E.

    2004  

    Author's details ed. by Stefan H. E. Kaufmann
    Keywords Impfstoff ; Forschung
    Subject Wissenschaftliche Forschung ; Forschungen ; Vaccine ; Vakzine ; Antikörperhaltiges Arzneimittel
    Language English
    Size XLII, 628 S. : Ill., graph. Darst.
    Publisher Wiley-VCH
    Publishing place Weinheim
    Publishing country Germany
    Document type Book
    HBZ-ID HT013766248
    ISBN 3-527-30523-8 ; 978-3-527-30523-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 725 order for loan Magazin

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  8. Book: The innate immune response to infection

    Kaufmann, Stefan H. E.

    2004  

    Author's details ed. by Stefan H. E. Kaufmann
    Keywords Immunity, Natural / physiology ; Bacterial Infections / immunology ; Immunity, Cellular / physiology ; Antibody Formation / physiology
    Language English
    Size XV, 465, VII S. : Ill.
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT013969717
    ISBN 1-55581-291-0 ; 978-1-55581-291-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 3199 order for loan Magazin

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  9. Book ; Online: Mycobacteria and TB

    Kaufmann, Stefan H. E.

    a valuable update for researchers and clinicians

    2003  

    Author's details vol. ed.: Stefan H. E. Kaufmann
    Language English
    Size X + 156 S.
    Publisher Karger
    Publishing place Basel
    Publishing country Switzerland
    Document type Book ; Online
    HBZ-ID TT050388256
    ISBN 978-3-318-00878-4 ; 3-318-00878-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  10. Book: Mycobacteria and TB

    Kaufmann, Stefan H. E.

    11 tables

    (Issues in infectious diseases ; 2)

    2003  

    Author's details ed. Stefan H. E. Kaufmann
    Series title Issues in infectious diseases ; 2
    Collection
    Keywords Tuberculosis / drug therapy ; Bacterial Vaccines ; Mycobacterium Tuberculosis ; Tuberculosis / microbiology ; Tuberculosis, Multidrug-resistant ; Tuberkulose ; Tuberkelbakterium
    Subject Tuberkulose ; Mycobacterium tuberculosis ; Tuberkelbacillus ; Kochsches Bakterium ; Tbc ; Tuberculosis
    Language English
    Size X, 155 S. : Ill., graph. Darst., 25 cm
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT013477992
    ISBN 3-8055-7459-2 ; 978-3-8055-7459-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2002 A 4575 order for loan Magazin

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