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  1. Article ; Online: BPNSTs: In the eye of the beholder.

    Kaufmann, Timothy J / Erickson, Bradley J

    Neuro-oncology

    2022  Volume 24, Issue 4, Page(s) 610–611

    MeSH term(s) Humans ; Nerve Sheath Neoplasms
    Language English
    Publishing date 2022-01-13
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noab296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5307: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: A new study in contrasts: brain MRI for the depiction of tumor metabolism.

    Kaufmann, Timothy J

    Neuro-oncology

    2019  Volume 21, Issue 9, Page(s) 1095–1096

    MeSH term(s) Brain/diagnostic imaging ; Glioma ; Humans ; Hydrogen-Ion Concentration ; Magnetic Resonance Imaging ; Oxygen
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2019-07-03
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noz121
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  3. Article ; Online: Can my computer tell me if this tumor is IDH mutated?

    Kaufmann, Timothy J / Erickson, Bradley J

    Neuro-oncology

    2020  Volume 22, Issue 3, Page(s) 311–312

    MeSH term(s) Brain ; Glioma ; Humans ; Magnetic Resonance Imaging ; Mutation
    Language English
    Publishing date 2020-01-06
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2028601-6
    ISSN 1523-5866 ; 1522-8517
    ISSN (online) 1523-5866
    ISSN 1522-8517
    DOI 10.1093/neuonc/noaa002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Standardized brain tumor imaging protocols for clinical trials: current recommendations and tips for integration.

    Sanvito, Francesco / Kaufmann, Timothy J / Cloughesy, Timothy F / Wen, Patrick Y / Ellingson, Benjamin M

    Frontiers in radiology

    2023  Volume 3, Page(s) 1267615

    Abstract: Standardized MRI acquisition protocols are crucial for reducing the measurement and interpretation variability associated with response assessment in brain tumor clinical trials. The main challenge is that standardized protocols should ensure high image ... ...

    Abstract Standardized MRI acquisition protocols are crucial for reducing the measurement and interpretation variability associated with response assessment in brain tumor clinical trials. The main challenge is that standardized protocols should ensure high image quality while maximizing the number of institutions meeting the acquisition requirements. In recent years, extensive effort has been made by consensus groups to propose different "ideal" and "minimum requirements" brain tumor imaging protocols (BTIPs) for gliomas, brain metastases (BM), and primary central nervous system lymphomas (PCSNL). In clinical practice, BTIPs for clinical trials can be easily integrated with additional MRI sequences that may be desired for clinical patient management at individual sites. In this review, we summarize the general concepts behind the choice and timing of sequences included in the current recommended BTIPs, we provide a comparative overview, and discuss tips and caveats to integrate additional clinical or research sequences while preserving the recommended BTIPs. Finally, we also reflect on potential future directions for brain tumor imaging in clinical trials.
    Language English
    Publishing date 2023-12-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-8740
    ISSN (online) 2673-8740
    DOI 10.3389/fradi.2023.1267615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Advanced Imaging in the Diagnosis and Response Assessment of High-Grade Glioma:

    Hu, Leland S / Smits, Marion / Kaufmann, Timothy J / Knutsson, Linda / Rapalino, Otto / Galldiks, Norbert / Sundgrene, Pia C / Cha, Soonmee

    AJR. American journal of roentgenology

    2024  

    Abstract: ... ...

    Abstract This
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.23.30612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Elevated Electrode Impedances During Deep Brain Stimulation Surgery May Be Due to Peri-Electrode Air Collections.

    Klassen, Bryan T / Rotter, Juliana / Crane, Colleen / Kaufmann, Timothy J / Miller, Kai J

    Cureus

    2022  Volume 14, Issue 1, Page(s) e21518

    Abstract: Deep brain stimulation (DBS) is a commonly used treatment for medically refractory movement disorders and epilepsy. Intraoperative testing of electrode impedances is routinely done during DBS surgery to identify electrical conduction defects in the ... ...

    Abstract Deep brain stimulation (DBS) is a commonly used treatment for medically refractory movement disorders and epilepsy. Intraoperative testing of electrode impedances is routinely done during DBS surgery to identify electrical conduction defects in the system. We present two illustrative cases involving elevated intraoperative impedances. In the first case, the temporal evolution of impedance changes and a postoperative head CT were consistent with a small and slowly resolving air collection along the lead. In the second case, an abnormally high impedance reading was observed at a single electrode and then "transferred" to be observed at an adjacent electrode upon adjustments of the electrode position, likely due to small air collection at a fixed position in the brain tissue. In both cases, careful troubleshooting allowed identification of the issue and avoidance of unnecessary surgical revisions. A thorough understanding of the possible sources of, and troubleshooting for, abnormal impedance readings is needed for effective intraoperative DBS monitoring.
    Language English
    Publishing date 2022-01-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.21518
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  7. Article ; Online: A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part 2-Newly Described and Revised Tumor Types.

    Guerin, Julie B / Kaufmann, Timothy J / Eckel, Laurence J / Morris, Jonathan M / Vaubel, Rachael A / Giannini, Caterina / Johnson, Derek R

    Radiology

    2023  Volume 307, Issue 5, Page(s) e221885

    Abstract: The fifth edition of the World Health Organization classification of tumors of the central nervous system (CNS), published in 2021, introduces major shifts in the classification of brain and spine tumors. These changes were necessitated by rapidly ... ...

    Abstract The fifth edition of the World Health Organization classification of tumors of the central nervous system (CNS), published in 2021, introduces major shifts in the classification of brain and spine tumors. These changes were necessitated by rapidly increasing knowledge of CNS tumor biology and therapies, much of which is based on molecular methods in tumor diagnosis. The growing complexity of CNS tumor genetics has required reorganization of tumor groups and acknowledgment of new tumor entities. For radiologists interpreting neuroimaging studies, proficiency with these updates is critical in providing excellent patient care. This review will focus on new or revised CNS tumor types and subtypes, beyond infiltrating glioma (described in part 1 of this series), with an emphasis on imaging features.
    MeSH term(s) Humans ; Central Nervous System Neoplasms/diagnostic imaging ; Glioma/diagnostic imaging ; Brain/pathology ; World Health Organization ; Radiologists ; Brain Neoplasms
    Language English
    Publishing date 2023-05-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.221885
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ue I Zs.106: Show issues Location:
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  8. Article ; Online: A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part I-Key Concepts and the Spectrum of Diffuse Gliomas.

    Johnson, Derek R / Giannini, Caterina / Vaubel, Rachael A / Morris, Jonathan M / Eckel, Laurence J / Kaufmann, Timothy J / Guerin, Julie B

    Radiology

    2023  Volume 306, Issue 2, Page(s) e229036

    Language English
    Publishing date 2023-01-23
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.229036
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    Ue I Zs.106: Show issues Location:
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  9. Article ; Online: The utility of diffusion tractography for speech preservation in laser ablation of the dominant insula: illustrative case.

    Kaufmann, Timothy J / Lehman, Vance T / Wong-Kisiel, Lily C / Kerezoudis, Panagiotis / Miller, Kai J

    Journal of neurosurgery. Case lessons

    2021  Volume 1, Issue 19, Page(s) CASE21113

    Abstract: Background: Open surgical treatment of insular epilepsy holds particular risk of injury to middle cerebral artery branches, the operculum (through retraction), and adjacent language-related white matter tracts in the language-dominant hemisphere. ... ...

    Abstract Background: Open surgical treatment of insular epilepsy holds particular risk of injury to middle cerebral artery branches, the operculum (through retraction), and adjacent language-related white matter tracts in the language-dominant hemisphere. Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (LITT) is a surgical alternative that allows precise lesioning with potentially less operative risk. The authors presented the case of a 13-year-old girl with intractable, MRI-negative, left (dominant hemisphere) insular epilepsy that was treated with LITT. Diffusion tensor imaging (DTI) tractography was used to aid full posterior insular lesioning in the region of stereo electroencephalography-determined seizure onset while avoiding thermal injury to the language-related superior longitudinal fasciculus (SLF)/arcuate fasciculus (AF) and inferior fronto-occipital fasciculus (IFOF).
    Observations: DTI tractography was used successfully in planning insular LITT and facilitated a robust insular ablation with sharp margins at the interfaces with the SLF/AF and IFOF. These tracts were spared, and no neurological deficits were induced through LITT.
    Lessons: Although it is technically demanding and has important limitations that must be understood, clinically available DTI tractography adds precision and confidence to insular laser ablation when used to protect important language-related white matter tracts.
    Language English
    Publishing date 2021-05-10
    Publishing country United States
    Document type Case Reports
    ISSN 2694-1902
    ISSN (online) 2694-1902
    DOI 10.3171/CASE21113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A Radiologist's Guide to the 2021 WHO Central Nervous System Tumor Classification: Part I-Key Concepts and the Spectrum of Diffuse Gliomas.

    Johnson, Derek R / Giannini, Caterina / Vaubel, Rachael A / Morris, Jonathan M / Eckel, Laurence J / Kaufmann, Timothy J / Guerin, Julie B

    Radiology

    2022  Volume 304, Issue 3, Page(s) 494–508

    Abstract: The fifth edition of the World Health Organization (WHO) classification of tumors of the central nervous system, published in 2021, contains substantial updates in the classification of tumor types. Many of these changes are relevant to radiologists, ... ...

    Abstract The fifth edition of the World Health Organization (WHO) classification of tumors of the central nervous system, published in 2021, contains substantial updates in the classification of tumor types. Many of these changes are relevant to radiologists, including "big picture" changes to tumor diagnosis methods, nomenclature, and grading, which apply broadly to many or all central nervous system tumor types, as well as the addition, elimination, and renaming of multiple specific tumor types. Radiologists are integral in interpreting brain tumor imaging studies and have a considerable impact on patient care. Thus, radiologists must be aware of pertinent changes in the field. Staying updated with the most current guidelines allows radiologists to be informed and effective at multidisciplinary tumor boards and in interactions with colleagues in neuro-oncology, neurosurgery, radiation oncology, and neuropathology. This review represents the first of a two-installment review series on the most recent changes to the WHO brain tumor classification system. This first installment focuses on the changes to the classification of adult and pediatric gliomas of greatest relevance for radiologists.
    MeSH term(s) Adult ; Brain Neoplasms/pathology ; Central Nervous System Neoplasms/diagnostic imaging ; Child ; Glioma/diagnostic imaging ; Glioma/pathology ; Humans ; Radiologists ; World Health Organization
    Language English
    Publishing date 2022-07-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.213063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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