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  1. Article: [Biliary drainage for malignant perihilar biliary obstruction].

    Kawakami, Hiroshi

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology

    2022  Volume 119, Issue 4, Page(s) 310–320

    MeSH term(s) Bile Duct Neoplasms/complications ; Bile Duct Neoplasms/diagnostic imaging ; Bile Duct Neoplasms/surgery ; Cholestasis/diagnostic imaging ; Cholestasis/etiology ; Cholestasis/surgery ; Drainage ; Humans ; Stents ; Treatment Outcome
    Language Japanese
    Publishing date 2022-04-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 708695-7
    ISSN 1349-7693 ; 0446-6586
    ISSN (online) 1349-7693
    ISSN 0446-6586
    DOI 10.11405/nisshoshi.119.310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Duodenoscope insertion difficulty due to perigastric adhesions overcome using an overtube.

    Kawakami, Hiroshi / Uchiyama, Naomi / Ogawa, Souichiro

    Journal of hepato-biliary-pancreatic sciences

    2023  Volume 30, Issue 12, Page(s) e84–e85

    Abstract: Kawakami and colleagues report a case of duodenoscope insertion difficulty through the pyloric ring due to perigastric adhesions which was successfully overcome using an overtube. The overtube can be attached to both standard and therapeutic ... ...

    Abstract Kawakami and colleagues report a case of duodenoscope insertion difficulty through the pyloric ring due to perigastric adhesions which was successfully overcome using an overtube. The overtube can be attached to both standard and therapeutic duodenoscopes, allowing successful biliary or pancreatic intervention in patients in whom duodenoscopic insertion is challenging.
    MeSH term(s) Humans ; Cholangiopancreatography, Endoscopic Retrograde ; Duodenoscopes ; Pancreas
    Language English
    Publishing date 2023-10-04
    Publishing country Japan
    Document type Case Reports
    ZDB-ID 2536236-7
    ISSN 1868-6982 ; 1868-6974
    ISSN (online) 1868-6982
    ISSN 1868-6974
    DOI 10.1002/jhbp.1362
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  3. Article ; Online: Newly developed dedicated guide sheath system for selective pancreatobiliary biopsy.

    Kawakami, Hiroshi / Uchiyama, Naomi / Hatada, Hiroshi

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

    2023  Volume 35, Issue 5, Page(s) e100–e102

    MeSH term(s) Humans ; Biopsy/instrumentation ; Biliary Tract
    Language English
    Publishing date 2023-05-28
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1171589-3
    ISSN 1443-1661 ; 0915-5635
    ISSN (online) 1443-1661
    ISSN 0915-5635
    DOI 10.1111/den.14593
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    Zs.A 3854: Show issues Location:
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  4. Article ; Online: Current status and issues in genomic analysis using EUS-FNA/FNB specimens in hepatobiliary-pancreatic cancers.

    Ozono, Yoshinori / Kawakami, Hiroshi / Uchiyama, Naomi / Hatada, Hiroshi / Ogawa, Souichiro

    Journal of gastroenterology

    2023  Volume 58, Issue 11, Page(s) 1081–1093

    Abstract: Comprehensive genomic profiling based on next-generation sequencing has recently been used to provide precision medicine for various advanced cancers. Endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) and EUS-guided fine-needle biopsy ( ... ...

    Abstract Comprehensive genomic profiling based on next-generation sequencing has recently been used to provide precision medicine for various advanced cancers. Endoscopic ultrasound (EUS)-guided fine-needle aspiration (EUS-FNA) and EUS-guided fine-needle biopsy (EUS-FNB) play essential roles in the diagnosis of abdominal masses, mainly pancreatic cancers. In recent years, CGP analysis using EUS-FNA/FNB specimens for hepatobiliary-pancreatic cancers has increased; however, the success rate of CGP analysis is not clinically satisfactory, and many issues need to be resolved to improve the success rate of CGP analysis. In this article, we review the transition from EUS-FNA to FNB, compare each test, and discuss the current status and issues in genomic analysis of hepatobiliary-pancreatic cancers using EUS-FNA/FNB specimens.
    Language English
    Publishing date 2023-09-12
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 1186495-3
    ISSN 1435-5922 ; 0944-1174
    ISSN (online) 1435-5922
    ISSN 0944-1174
    DOI 10.1007/s00535-023-02037-z
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    Zs.A 620: Show issues Location:
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  5. Article: Atrial fibrillation arising from a silent superior vena cava.

    Fujisawa, Tomoki / Nagai, Takayuki / Kawakami, Hiroshi / Yamaguchi, Osamu

    HeartRhythm case reports

    2022  Volume 9, Issue 3, Page(s) 156–159

    Language English
    Publishing date 2022-12-07
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2022.12.002
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  6. Article ; Online: The person has no left atrial appendage by nature: a rare anatomical cardiac condition.

    Kawakami, Hiroshi / Fujisawa, Tomoki / Nagai, Takayuki / Yamaguchi, Osamu

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2022  Volume 63, Issue 3, Page(s) 739–740

    MeSH term(s) Atrial Appendage/diagnostic imaging ; Atrial Appendage/surgery ; Atrial Fibrillation/diagnostic imaging ; Atrial Fibrillation/surgery ; Echocardiography, Transesophageal ; Heart Diseases ; Humans
    Language English
    Publishing date 2022-01-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-021-01107-7
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    Zs.A 5214: Show issues Location:
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  7. Article ; Online: Evaluation of health utility in trial-based cost-utility analyses for major cardiovascular disease: protocol for a systematic review.

    Nakao, Yasuhisa / Kawakami, Hiroshi / Miyazaki, Shigehiro / Saito, Makoto / Luo, Yan / Yamamoto, Kazumichi / Yamaguchi, Osamu

    BMJ open

    2023  Volume 13, Issue 5, Page(s) e067045

    Abstract: Introduction: The global incidence of cardiovascular disease (CVD) is high, and the medical costs associated with its management have been increasing. Cost-utility analyses (CUAs) are essential for understanding the value of healthcare interventions and ...

    Abstract Introduction: The global incidence of cardiovascular disease (CVD) is high, and the medical costs associated with its management have been increasing. Cost-utility analyses (CUAs) are essential for understanding the value of healthcare interventions and for decision-making. A majority of the CUAs for CVD are model based and have cited health utilities from previously published data; standard health utilities for the CUAs of CVD have not been established yet. Thus, we aim to identify the standard utilities according to the patients' condition and disease severity in patients with major CVDs.
    Methods and analysis: We will search Medline and Evidence-Based Medicine Reviews for trial-based CUA studies that have reported on quality-adjusted life-years using original health utilities for patients with three major forms of CVD (coronary artery disease, heart failure and atrial fibrillation). Papers on trial-based CUAs will be included, while those on model-based CUAs will be excluded. No restrictions will be made in terms of intervention type. The main outcome comprises the health utilities calculated on a scale of 0-1 (irrespective of the measurement methods) at baseline and after treatment. Two independent investigators will screen the eligibility of articles; they will extract data, including health utilities, from the eligible articles for further analysis. The quality of the included studies will be assessed using the Consolidated Health Economic Evaluation Reporting Standards checklist. We will describe the means and SDs of the health utilities from all the included studies. The mean utility weights for individual studies will be combined through meta-analyses using a random-effects model to obtain the representative health utility value for each disease. Subgroup analyses will be conducted according to the severity and duration of each disease.
    Ethics and dissemination: Ethical approval is not required. The review will be submitted to an appropriate peer-reviewed journal.
    Prospero registration number: CRD42022316278.
    MeSH term(s) Humans ; Cardiovascular Diseases/therapy ; Cost-Benefit Analysis ; Coronary Artery Disease ; Heart Failure ; Atrial Fibrillation
    Language English
    Publishing date 2023-05-09
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-067045
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  8. Article ; Online: The successful posterior sectionectomy accompanied with caudate lobectomy for hepatocellular carcinoma located in segment 1 after LEN-TACE: a case report.

    Nanashima, Atsushi / Hamada, Takeomi / Hiyoshi, Masahide / Imamura, Naoya / Tsuchimochi, Yuki / Shimizu, Ikko / Nagata, Kenji / Kawakami, Hiroshi

    Clinical journal of gastroenterology

    2024  

    Abstract: Nowadays, the novel molecular targeting chemotherapy provides possibility of safe hepatectomy for progressive hepatocellular carcinoma (HCC). Further, combination of the conventional transarterial chemoembolization (TACE) may add an effect of tumor ... ...

    Abstract Nowadays, the novel molecular targeting chemotherapy provides possibility of safe hepatectomy for progressive hepatocellular carcinoma (HCC). Further, combination of the conventional transarterial chemoembolization (TACE) may add an effect of tumor shrink. We present a successful radical hepatectomy for a large HCC located in segment 1 accompanied with the preoperative Lenvatinib (LEN)-TACE sequential treatment. We present a woman patient without any complaints who had a 7 cm-in-size of solitary HCC compressing vena cava and right portal pedicle. To achieve radical hepatectomy by tumor shrinking, LEN-TACE for 2 months. After confirming downsizing or devascularization of the HCC, we scheduled radical posterior sectionectomy combined with caudate lobectomy according to tumor location and expected future remnant liver volume from three-dimensional computed tomography simulation before surgery. Under the thoraco-abdominal incision laparotomy, we safely achieved scheduled radical hepatectomy without any vascular injuries. The postoperative course was uneventful and no tumor recurrence were observed for 1 year. Histological findings showed the Japan TNM stage III HCC with 70% necrosis. The multi-modal strategy of LEN-TACE followed by radical hepatectomy by confirming downsizing or devascularization in tumor is supposed to be useful and would be a preoperative chemotherapy option, and promising for curative treatment in HCC patients with progressive or large HCC, which may lead to safety by prevention surrounding major vascular injury.
    Language English
    Publishing date 2024-02-14
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2429411-1
    ISSN 1865-7265 ; 1865-7257
    ISSN (online) 1865-7265
    ISSN 1865-7257
    DOI 10.1007/s12328-024-01929-8
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  9. Article ; Online: Reactivation of hepatitis C virus caused by steroid monotherapy for sudden deafness.

    Kaneko, Hiroki / Ozono, Yoshinori / Iwakiri, Hisayoshi / Hatada, Hiroshi / Uchiyama, Naomi / Komaki, Yuri / Nakamura, Kenichi / Hasuike, Satoru / Nagata, Kenji / Kawakami, Hiroshi

    Clinical journal of gastroenterology

    2024  

    Abstract: Hepatitis C virus (HCV) reactivation has been reported to be caused due to several anticancer drugs and immunosuppressive agents; however, HCV reactivation after steroid monotherapy has rarely been reported. Here, we report the case of a 65-year-old ... ...

    Abstract Hepatitis C virus (HCV) reactivation has been reported to be caused due to several anticancer drugs and immunosuppressive agents; however, HCV reactivation after steroid monotherapy has rarely been reported. Here, we report the case of a 65-year-old Japanese man with HCV infection who developed HCV reactivation after the administration of prednisolone (PSL) for 6 days for sudden deafness. In the patient history, the positivity for anti-HCV antibody was observed, but serum level of HCV RNA was not measured. Two months after PSL administration, the patient experienced an alanine aminotransferase (ALT) flare and the serum level of HCV RNA was observed to be 6.2 log IU/mL; then, the patient was admitted to our hospital for hepatitis treatment. Based on the clinical course and laboratory findings, the patient was diagnosed with HCV reactivation. Although the ALT levels decreased spontaneously during follow-up, they did not drop to normal range; subsequently, sofosbuvir and ledipasvir treatments were started. A sustained virological response 24 weeks after the end of treatment was achieved. This case study suggests that HCV reactivation with hepatitis flare can occur even after a steroid monotherapy, and doctors should pay attention to HCV reactivation when administering PSL for patients with HCV infection.
    Language English
    Publishing date 2024-04-08
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2429411-1
    ISSN 1865-7265 ; 1865-7257
    ISSN (online) 1865-7265
    ISSN 1865-7257
    DOI 10.1007/s12328-024-01944-9
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  10. Article ; Online: A novel integrated inside biliary stent and nasobiliary drainage catheter system for biliary drainage (with video).

    Kawakami, Hiroshi / Itoi, Takao

    Journal of hepato-biliary-pancreatic sciences

    2019  Volume 27, Issue 3, Page(s) 149–150

    Abstract: Highlight Kawakami and UMIDAS Inc. developed a novel biliary drainage system consisting of a 7- or 8.5-Fr inside biliary stent, a 4-Fr nasobiliary drainage catheter and a 7.5-Fr pushing catheter. It is the least invasive approach available for the ... ...

    Abstract Highlight Kawakami and UMIDAS Inc. developed a novel biliary drainage system consisting of a 7- or 8.5-Fr inside biliary stent, a 4-Fr nasobiliary drainage catheter and a 7.5-Fr pushing catheter. It is the least invasive approach available for the management of acute cholangitis and biliary drainage in patients with benign and malignant perihilar biliary obstruction.
    MeSH term(s) Catheters ; Cholangitis/surgery ; Drainage/instrumentation ; Endoscopy ; Equipment Design ; Female ; Humans ; Liver Transplantation ; Middle Aged ; Postoperative Complications/surgery ; Stents
    Language English
    Publishing date 2019-11-28
    Publishing country Japan
    Document type Journal Article ; Video-Audio Media
    ZDB-ID 2536236-7
    ISSN 1868-6982 ; 1868-6974
    ISSN (online) 1868-6982
    ISSN 1868-6974
    DOI 10.1002/jhbp.693
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