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  1. Article: Visibility of the bleeding point in acute rectal hemorrhagic ulcer using red dichromatic imaging: A case report.

    Hirai, Yuichiro / Kayashima, Atsuto / Nakazato, Yoshihiro / Fujimoto, Ai

    World journal of gastrointestinal endoscopy

    2021  Volume 13, Issue 7, Page(s) 233–237

    Abstract: Background: Red dichromatic imaging (RDI) is a novel image-enhanced endoscopy expected to improve the visibility of the bleeding point. However, it has not been thoroughly investigated.: Case summary: A 91-year-old man developed a sudden massive ... ...

    Abstract Background: Red dichromatic imaging (RDI) is a novel image-enhanced endoscopy expected to improve the visibility of the bleeding point. However, it has not been thoroughly investigated.
    Case summary: A 91-year-old man developed a sudden massive hematochezia and underwent emergent colonoscopy. An ulcer with pulsatile bleeding was found on the lower rectum. Due to massive bleeding, the exact location of the bleeding point was not easy to detect with white light imaging (WLI). Upon switching to RDI, the bleeding point appeared in deeper yellow compared to the surrounding blood. Thus, RDI enabled us for easier recognition of the bleeding point, and hemostasis was achieved successfully. Furthermore, we reviewed endoscopic images and evaluated the color difference between the bleeding point and surrounding blood for WLI and RDI. In our case, the color difference of RDI was greater than that of WLI (9. 75
    Conclusion: RDI may improve visualization of the bleeding point by providing better contrast in color difference relative to surrounding blood.
    Language English
    Publishing date 2021-07-15
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2573698-X
    ISSN 1948-5190
    ISSN 1948-5190
    DOI 10.4253/wjge.v13.i7.233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Successful transpapillary removal of a migrated percutaneous transhepatic biliary drainage tube with a digital peroral cholangioscope.

    Kayashima, Atsuto / Iwasaki, Eisuke / Kanai, Takanori

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

    2021  Volume 34, Issue 1, Page(s) e3–e4

    MeSH term(s) Biliary Tract Surgical Procedures ; Catheterization ; Drainage ; Humans ; Laparoscopy
    Language English
    Publishing date 2021-09-29
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1171589-3
    ISSN 1443-1661 ; 0915-5635
    ISSN (online) 1443-1661
    ISSN 0915-5635
    DOI 10.1111/den.14135
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3854: Show issues Location:
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  3. Article ; Online: Efficacy of a novel ultra-tapered endoscopic nasobiliary drainage tube in gallbladder drainage.

    Hayakawa, Takaoki / Iwasaki, Eisuke / Okada, Haruka / Nakajima, Yuki / Kayashima, Atsuto / Kawasaki, Shintaro / Horibe, Masayasu / Kanai, Takanori

    VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

    2024  Volume 9, Issue 4, Page(s) 208–210

    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4481
    ISSN (online) 2468-4481
    DOI 10.1016/j.vgie.2024.01.003
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  4. Article ; Online: Successful radiotherapy for recurrent obstructive pancreatitis secondary to pancreatic metastasis from cervical squamous-cell carcinoma.

    Nakajima, Yuki / Iwasaki, Eisuke / Kayashima, Atsuto / Machida, Yujiro / Kawasaki, Shintaro / Horibe, Masayasu / Kawaida, Miho / Masugi, Yohei / Iwata, Takashi / Kanai, Takanori

    Clinical journal of gastroenterology

    2023  Volume 16, Issue 5, Page(s) 755–760

    Abstract: Metastatic pancreatic cancer is a rare condition and cases of pancreatic metastasis from cervical cancer are infrequently reported. Furthermore, the incidence rates of pancreatic tumors as the cause of pancreatitis and of pancreatitis in patients with ... ...

    Abstract Metastatic pancreatic cancer is a rare condition and cases of pancreatic metastasis from cervical cancer are infrequently reported. Furthermore, the incidence rates of pancreatic tumors as the cause of pancreatitis and of pancreatitis in patients with pancreatic tumors are similarly low. Pancreatitis may occur when a tumor obstructs the pancreatic duct. This condition may be difficult to manage and significantly reduces the quality of life because of severe abdominal pain. Here, we present a rare case of obstructive pancreatitis caused by pancreatic metastasis from cervical squamous-cell carcinoma, pathologically confirmed using endoscopic ultrasonography-guided fine-needle biopsy and treated with palliative irradiation to achieve rapid therapeutic relief. It is important to obtain appropriate tissue samples, confirm the pathological diagnosis, and compare the pathological findings with those of the primary tumor to select the appropriate treatment for obstructive pancreatitis caused by a metastatic pancreatic tumor.
    MeSH term(s) Female ; Humans ; Uterine Cervical Neoplasms/radiotherapy ; Uterine Cervical Neoplasms/pathology ; Quality of Life ; Pancreas/pathology ; Pancreatic Neoplasms/pathology ; Pancreatitis, Chronic ; Carcinoma, Squamous Cell/radiotherapy ; Carcinoma, Squamous Cell/pathology
    Language English
    Publishing date 2023-06-03
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2429411-1
    ISSN 1865-7265 ; 1865-7257
    ISSN (online) 1865-7265
    ISSN 1865-7257
    DOI 10.1007/s12328-023-01817-7
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  5. Article ; Online: Non-interventional Management of Asymptomatic Diminutive Choledocholithiasis Versus Endoscopic Extraction in Consecutive Patients.

    Kayashima, Atsuto / Horibe, Masayasu / Iwasaki, Eisuke / Bazerbachi, Fateh / Okada, Haruka / Nakajima, Yuki / Mizukami, Yosuke / Machida, Yujiro / Kawasaki, Shintaro / Kitago, Minoru / Kanai, Takanori

    Digestive diseases and sciences

    2023  Volume 68, Issue 12, Page(s) 4456–4465

    Abstract: Background: Current guidelines recommend treating choledocholithiasis, regardless of symptoms or stone size, with endoscopic retrograde cholangiopancreatography (ERCP). However, asymptomatic choledocholithiasis, discovered incidentally on imaging, may ... ...

    Abstract Background: Current guidelines recommend treating choledocholithiasis, regardless of symptoms or stone size, with endoscopic retrograde cholangiopancreatography (ERCP). However, asymptomatic choledocholithiasis, discovered incidentally on imaging, may carry a higher risk of ERCP-related adverse events, and some asymptomatic and diminutive stones may not cause biliary adverse events during extended follow-up. Therefore, we aimed to clarify the best treatment strategies for asymptomatic choledocholithiasis based on stone size.
    Methods: We retrospectively identified patients with incidental imaging-found asymptomatic diminutive (≤ 4 mm) or non-diminutive (> 4 mm) choledocholithiasis and divided them into two groups: those who did not undergo ERCP and were treated when complications arose (on-demand group) and those who underwent ERCP before being symptomatic (intervention group). Adverse events were defined as any biliary or pancreatic complication related to ERCP or arising during observation or after intervention. The primary outcome was the adjusted overall adverse event-free survival using the propensity score-based matching weights method comparing the two groups of stone size.
    Results: Among 148 patients identified (median follow-up period, 969 days), 68 had diminutive stones and 80 had non-diminutive stones. Of the 68 patients with diminutive stones, 51 were in the on-demand group and 17 in the intervention group. The overall adjusted adverse event-free survival was significantly higher in the on-demand group for diminutive stones (97.4% and 70.1%, respectively, at 3 years; p = 0.01).
    Discussion: Patients with incidental imaging-detected asymptomatic diminutive choledocholithiasis may benefit from clinical observation, pursuing ERCP when symptoms develop.
    MeSH term(s) Humans ; Choledocholithiasis/diagnostic imaging ; Choledocholithiasis/surgery ; Retrospective Studies ; Cholangiopancreatography, Endoscopic Retrograde/adverse effects ; Sphincterotomy, Endoscopic/methods ; Biliary Tract
    Language English
    Publishing date 2023-10-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-023-08137-3
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    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.35: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Propensity score matching analysis for adverse events of EUS-guided biliary drainage in advanced elderly patients (PEACE study).

    Ogura, Takeshi / Ishiwatari, Hirotoshi / Fujimori, Nao / Iwasaki, Eisuke / Ishikawa, Kazuma / Satoh, Tatsunori / Kaneko, Junichi / Sato, Junya / Oono, Takamasa / Matsumoto, Kazuhide / Fukuhara, Seiichiro / Kayashima, Atsuto / Hakoda, Akitoshi / Higuchi, Kazuhide

    Therapeutic advances in gastroenterology

    2022  Volume 15, Page(s) 17562848221092612

    Abstract: Background: Several studies have suggested that elderly patients, as well as younger patients, can be safely treated using endoscopic retrograde cholangiopancreatography (ERCP). However, endoscopic ultrasound-guided biliary drainage (EUS-BD) has not ... ...

    Abstract Background: Several studies have suggested that elderly patients, as well as younger patients, can be safely treated using endoscopic retrograde cholangiopancreatography (ERCP). However, endoscopic ultrasound-guided biliary drainage (EUS-BD) has not been clinically evaluated for very elderly patients. The present multicenter, retrospective study aimed to determine the safety of EUS-BD for advanced elderly patients.
    Method: Patients who underwent EUS-BD during this period were retrospectively enrolled, and they were divided into two groups based on age: group A (age  < 75 years) and group B (age ⩾ 75). In this study, capnographic monitoring was used only for elderly patients (age ⩾ 75 years).
    Results: A total of 271 patients who underwent EUS-BD were enrolled in this study (group A = 177, group B = 94). The types of adverse events that were associated with EUS-BD was observed in 38 patients, and they did not differ significantly between two groups (
    Conclusion: In conclusion, EUS-BD could be safety performed in advanced elderly patients, the same as in younger patients. Also, capnographic monitoring might be helpful in case of sedation by a gastroenterologist in a non-intubated patient. Further prospective, randomized studies are needed to confirm these conclusions.
    Language English
    Publishing date 2022-05-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2440710-0
    ISSN 1756-2848 ; 1756-283X
    ISSN (online) 1756-2848
    ISSN 1756-283X
    DOI 10.1177/17562848221092612
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  7. Article ; Online: Ulcerative colitis exacerbation after the onset of immune checkpoint inhibitor related colitis.

    Kayashima, Atsuto / Shimozaki, Keitaro / Hirata, Kenro / Mutaguchi, Makoto / Takabayashi, Kaoru / Hayashi, Yuichiro / Hosoe, Naoki / Ogata, Haruhiko / Sujino, Tomohisa / Kanai, Takanori

    Clinical journal of gastroenterology

    2020  Volume 14, Issue 1, Page(s) 152–158

    Abstract: Immune checkpoint inhibitors (ICPI) have been reported to be effective in various carcinomas. They excessively activate the immune system, resulting in frequent immune-related adverse events (irAEs). Colitis induced by ICPI is one of the most common and ... ...

    Abstract Immune checkpoint inhibitors (ICPI) have been reported to be effective in various carcinomas. They excessively activate the immune system, resulting in frequent immune-related adverse events (irAEs). Colitis induced by ICPI is one of the most common and is known as immune-mediated colitis (IMC). Although IMC and inflammatory bowel disease (IBD) are similar in many respects, there are very few reports of IMC in patients with preexisting IBD such as ulcerative colitis (UC) and Crohn's disease (CD). Whether preexisting IBD is concerned with the development of the colitis is not well known. Here, we reported the case who developed severe ulcerative colitis which started from IMC. It is an important case to follow the time course of the colitis developed. Our conclusion indicated that frequent colonoscopy was important for the management of IMC in a patient who has suffered chronic inflammatory disease, such as UC.
    MeSH term(s) Colitis/chemically induced ; Colitis, Ulcerative/drug therapy ; Crohn Disease/drug therapy ; Humans ; Immune Checkpoint Inhibitors ; Inflammatory Bowel Diseases
    Chemical Substances Immune Checkpoint Inhibitors
    Language English
    Publishing date 2020-10-14
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2429411-1
    ISSN 1865-7265 ; 1865-7257
    ISSN (online) 1865-7265
    ISSN 1865-7257
    DOI 10.1007/s12328-020-01261-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Endoscopic Diagnosis of Biliary Stricture Combined with Digital Cholangioscope: A Case Series.

    Fukuhara, Seiichiro / Iwasaki, Eisuke / Kayashima, Atsuto / Machida, Yujiro / Tamagawa, Hiroki / Kawasaki, Shintaro / Horibe, Masayasu / Hori, Shutaro / Abe, Yuta / Kitago, Minoru / Ogata, Haruhiko / Kanai, Takanori

    Healthcare (Basel, Switzerland)

    2021  Volume 10, Issue 1

    Abstract: The endoscopic diagnosis of biliary tract lesions is applied as a non-invasive method; however, its diagnostic accuracy is not yet high. Moreover, digital cholangioscopy is used for directly visualizing the inside of the bile duct, resulting in a more ... ...

    Abstract The endoscopic diagnosis of biliary tract lesions is applied as a non-invasive method; however, its diagnostic accuracy is not yet high. Moreover, digital cholangioscopy is used for directly visualizing the inside of the bile duct, resulting in a more precise biopsy. We present the case series of the outcomes of diagnosis using digital cholangioscopy in patients who underwent cholangioscopy for the evaluation of biliary stenosis in our department between January 2014 and March 2021. The controls were those who underwent a biopsy for biliary stenosis with conventional endoscopic retrograde cholangiopancreatography (ERCP). Background data for each case were collected, and the clinical outcomes by biopsy were evaluated, focusing on the accuracy of the diagnosis. Cholangioscopy was performed in 15 cases, while a conventional biopsy by ERCP was performed in 172 cases. Nine of 15 cases (60.0%) were diagnosed with cholangiocarcinoma. The number of specimens obtained through conventional ERCP and cholangioscopy was 2.5 ± 1.3 and 3.3 ± 1.5, respectively (
    Language English
    Publishing date 2021-12-22
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare10010012
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  9. Article: Endoscopic Ultrasound-Guided Sampling for Personalized Pancreatic Cancer Treatment.

    Iwasaki, Eisuke / Fukuhara, Seiichiro / Horibe, Masayasu / Kawasaki, Shintaro / Seino, Takashi / Takimoto, Yoichi / Tamagawa, Hiroki / Machida, Yujiro / Kayashima, Atsuto / Noda, Marin / Hayashi, Hideyuki / Kanai, Takanori

    Diagnostics (Basel, Switzerland)

    2021  Volume 11, Issue 3

    Abstract: Pancreatic cancer is the most lethal solid malignancy, and the number of patients with pancreatic cancer is increasing. Systemic chemotherapies are often ineffective for such patients, and there is an urgent need for personalized medicine. Unlike other ... ...

    Abstract Pancreatic cancer is the most lethal solid malignancy, and the number of patients with pancreatic cancer is increasing. Systemic chemotherapies are often ineffective for such patients, and there is an urgent need for personalized medicine. Unlike other types of cancer, personalized treatments for pancreatic cancer are still in development. Consequently, pancreatic cancer is less sensitive to anticancer drugs and is often refractory to common treatments. Therefore, advances in personalized medicine for pancreatic cancer are necessary. This review examined advances in personalized medicine for pancreatic cancer, including the use of endoscopic ultrasound (EUS)-guided sampling. EUS-guided sampling is widely used for diagnosing pancreatic tumors and is expected to be applied to sampled tissues. Additionally, there has been an increase in clinical research using EUS-guided sampling. The combination of precision medicine using genomic testing and pharmacological profiles based on high-throughput drug sensitivity testing using patient-derived organoids is expected to revolutionize pancreatic cancer treatment.
    Language English
    Publishing date 2021-03-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics11030469
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  10. Article: An Esophageal Ulcer Associated with a Thoracoabdominal Aortic Aneurysm.

    Kayashima, Atsuto / Mori, Hideki / Okuzawa, Anna / Kubosawa, Yoko / Hirai, Yuichiro / Kinoshita, Satoshi / Nakazato, Yoshihiro / Fujimoto, Ai / Kikuchi, Masahiro

    Case reports in gastroenterology

    2019  Volume 13, Issue 1, Page(s) 214–218

    Abstract: An aortoesophageal fistula, an abnormal anatomical communication between the aorta and the esophagus, is a rare cause of upper gastrointestinal bleeding. The mortality rate of patients with this condition is very high. A 77-year-old man, who had ... ...

    Abstract An aortoesophageal fistula, an abnormal anatomical communication between the aorta and the esophagus, is a rare cause of upper gastrointestinal bleeding. The mortality rate of patients with this condition is very high. A 77-year-old man, who had undergone endovascular aortic repair for a ruptured abdominal aortic aneurysm, developed melena. An upper gastrointestinal endoscopy was performed. This detected an esophageal ulcer, which had the potential to develop into an aortoesophageal fistula. Therefore, thoracic endovascular aortic repair was performed on the following day. Thereafter, the course was uneventful. We encountered a rare case of an esophageal ulcer associated with a thoracoabdominal aortic aneurysm before it developed into an aortoesophageal fistula.
    Language English
    Publishing date 2019-04-23
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000500067
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