LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 5 of total 5

Search options

  1. Article ; Online: The association between ulcerative colitis and COVID-19 severity: a systematic review and meta-analysis systematic review.

    Yang, Jingjing / Ke, Jianlin / Jiang, Xueliang / Wang, Lei

    International journal of colorectal disease

    2023  Volume 39, Issue 1, Page(s) 5

    Abstract: Purpose: After the COVID-19 pandemic, many challenges arose regarding the impact of this disease on people with ulcerative colitis. The aims of this study were to estimate the prevalence, severity, and death consequences of COVID-19 in patients with ... ...

    Abstract Purpose: After the COVID-19 pandemic, many challenges arose regarding the impact of this disease on people with ulcerative colitis. The aims of this study were to estimate the prevalence, severity, and death consequences of COVID-19 in patients with ulcerative colitis using a systematic review and meta-analysis.
    Methods: This study was conducted using a systematic review and meta-analysis method in the field of prevalence, severity, and clinical consequences of COVID-19 in people with ulcerative colitis worldwide. The search was conducted in international scientific databases, such as Web of Science, PubMed, Scopus, Cochrane Library, and Google Scholar, from the beginning of 2020 to October 2023. The quality of the eligible studies was assessed using the Strobe and Newcastle Ottawa checklists. The data were analyzed using a fixed-effects model in the meta-analysis. Subgroup analysis and meta-regression were performed using STATA version 17.
    Results: Nineteen studies with a sample size of 224,520 patients were included in this meta-analysis. The results showed that, in COVID-19 patients with ulcerative colitis, the prevalence of hospitalization, death, COVID-19 severity, and mortality rate in severe patients was 54% (95% CI, 27-80%), 10% (95% CI, 4-16%), 20% (95% CI, 8-34%), 63% (95% CI, 46-80%), respectively. In comparison with the general population, the odds ratio (OR) of hospitalization in patients due to COVID-19 was OR = 1.28 (95% CI, 1.19-1.38, P < 0.001), and the chance of severe COVID-19 was OR = 1.30 (95% CI, 1.22-1.53, P < 0.001).
    Conclusion: The probability of contracting the severe type of COVID-19 and hospitalization in patients with ulcerative colitis was higher than in the general population.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/epidemiology ; Pandemics ; Databases, Factual ; Hospitalization
    Language English
    Publishing date 2023-12-18
    Publishing country Germany
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 84975-3
    ISSN 1432-1262 ; 0179-1958
    ISSN (online) 1432-1262
    ISSN 0179-1958
    DOI 10.1007/s00384-023-04568-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: Anti-Arrhythmic Effects of Linalool

    Ke, Jianlin / Zhu, Canzhan / Zhang, Yuanyuan / Zhang, Wenlong

    Frontiers in pharmacology

    2020  Volume 11, Page(s) 926

    Abstract: Background: Lavender is a traditional therapy for different heart symptoms including palpitation, which comprises an important symptom of cardiac arrhythmias. This experiment was designed to evaluate the antiarrhythmic effects of linalool using an ... ...

    Abstract Background: Lavender is a traditional therapy for different heart symptoms including palpitation, which comprises an important symptom of cardiac arrhythmias. This experiment was designed to evaluate the antiarrhythmic effects of linalool using an experimental model of arrhythmia following myocardial infarction in rats. The underlying electrophysiological mechanism through cardiac connexin 43 (Cx43) expression was also investigated.
    Methods: Fifty male Sprague-Dawley rats were divided into five equal groups. The first group was considered as the normal control group; MI was induced by ligation of the left anterior descending artery (LAD) in the second group. The other three groups received metoprolol (100 mg/kg/day) or linalool (50 or 100 mg/kg/day) for seven days before LAD ligation. The arrhythmia score, isolated myocyte resting potential, histological changes, and cardiac Cx43 expression levels were evaluated.
    Results: In the MI group, there was a significant increase in the arrhythmia score but a marked decrease in resting membrane potential relative to the control; these changes were prevented by the administration of metoprolol or linalool. The histological changes were also minimized in the groups treated with these substances compared to the untreated MI group. The western blot and real-time PCR results showed that the protein expression of Cx43 in the infarct zone of the rat hearts was significantly higher in the MI groups receiving metoprolol or linalool compared with the untreated MI group.
    Conclusion: Linalool was shown to be able to dose-dependently decrease the incidence of arrhythmias in a rat model of myocardial infarction. We propose that the key mechanism behind this antiarrhythmic effect is probably the prevention of decreased Cx43 expression following MI.
    Language English
    Publishing date 2020-06-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2020.00926
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Study on Risk Factors for Death from Cardiomyopathy and Effectiveness of Health Information Management.

    Wang, Lei / Zhang, Shuping / Wang, Yan / Xuan, Jin / Han, Yanli / Ke, Jianlin

    Journal of healthcare engineering

    2021  Volume 2021, Page(s) 3922611

    Abstract: Objective: To explore risk factors for death from cardiomyopathy and the effectiveness of health information management (HIM).: Methods: A total of 80 patients with cardiomyopathy admitted in ICU of our hospital (January 2016-January 2020) were ... ...

    Abstract Objective: To explore risk factors for death from cardiomyopathy and the effectiveness of health information management (HIM).
    Methods: A total of 80 patients with cardiomyopathy admitted in ICU of our hospital (January 2016-January 2020) were selected as study subjects, and the clinical data of the patients were retrospectively analyzed. The patients were divided into the survival group (
    Results: No significant difference was found in baseline body mass, myocardial enzymes, troponin, infection factors, history of heart disease, and gender between the survival group and the death group (
    Conclusion: Older age, lower LVEF, and higher scores of APACHE II and SOFA are all risk factors for death from cardiomyopathy. Lower LVEF is an independent risk factor, and LVEF below 24.69% is an important indicator of increased risk of death. Moreover, HIM can effectively improve short-term treatment efficacy but has little effect on the long-term survival rate.
    MeSH term(s) Aged ; Cardiomyopathies ; Health Information Management ; Humans ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2021-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2545054-2
    ISSN 2040-2309 ; 2040-2295
    ISSN (online) 2040-2309
    ISSN 2040-2295
    DOI 10.1155/2021/3922611
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Identification and Verification of Potential Hub Genes in Amphetamine-Type Stimulant (ATS) and Opioid Dependence by Bioinformatic Analysis.

    Zhang, Wei / Deng, Xiaodong / Liu, Huan / Ke, Jianlin / Xiang, Mingliang / Ma, Ying / Zhang, Lixia / Yang, Ming / Liu, Yun / Huang, Feijun

    Frontiers in genetics

    2022  Volume 13, Page(s) 837123

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2022-03-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.837123
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: ERCC1

    Deng, Xiao-Dong / Ke, Jian-Lin / Chen, Tai-Yu / Gao, Qin / Zhao, Zhuo-Lin / Zhang, Wei / Liu, Huan / Xiang, Ming-Liang / Wang, Li-Zhen / Ma, Ying / Liu, Yun

    Frontiers in neurology

    2023  Volume 13, Page(s) 998428

    Abstract: Background: Excision repair cross-complementing group 1 (: Methods: A total of 513 patients with ischemic stroke and 550 control subjects were recruited. The expression levels of : Results: The : Conclusion: It was suggested that ... ...

    Abstract Background: Excision repair cross-complementing group 1 (
    Methods: A total of 513 patients with ischemic stroke and 550 control subjects were recruited. The expression levels of
    Results: The
    Conclusion: It was suggested that the
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2022.998428
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top