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  1. AU="Keane, Stephen"
  2. AU="Marsela, Enklajd"
  3. AU="Tate, Amanda W"
  4. AU="Solodov, E P"
  5. AU="Cheng-Fang Yen"

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  1. Artikel: A Case Report of Biventricular Arrhythmogenic Cardiomyopathy in a Middle-Aged Female.

    Mohamed, Sarra / Keane, Stephen / McNally, Clare / Hayes, James

    Cureus

    2022  Band 14, Heft 1, Seite(n) e20885

    Abstract: Arrhythmogenic cardiomyopathy is an inherited disease in which the normal myocardium is replaced by fibroadipose infiltrates. It is increasingly being recognized as a separate entity to arrhythmogenic right ventricular cardiomyopathy though is rarely ... ...

    Abstract Arrhythmogenic cardiomyopathy is an inherited disease in which the normal myocardium is replaced by fibroadipose infiltrates. It is increasingly being recognized as a separate entity to arrhythmogenic right ventricular cardiomyopathy though is rarely diagnosed. We report a 47-year-old female who presented to her local emergency department with a history of presyncope while driving. Electrocardiograph revealed inferolateral ST changes and right bundle branch block. A high burden of premature ventricular contractions and non-sustained ventricular tachycardia was seen on telemetry. Echocardiography showed reduced left ventricular systolic function and cardiac magnetic resonance imaging demonstrated extensive fibrosis involving the left ventricle and the septum of the right ventricle. An inherited cardiac disease genetic panel, including desmosomal gene mutations, was non-contributary. Extensive workup for other potential causes of cardiac fibrosis and reduced left ventricle function including cardiac positron emission tomography (PET) was negative. Based on the presentation and these findings, a diagnosis of biventricular arrhythmogenic cardiomyopathy was made. The patient's condition was complicated by third-degree heart block two weeks after initiation of pharmacological treatment that included amiodarone. An implantable cardiac defibrillator was implanted. She was referred to a tertiary centre specializing in inherited cardiac conditions for familial screening.
    Sprache Englisch
    Erscheinungsdatum 2022-01-03
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.20885
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Characterization of atrial histology in a patient with hypertrophic cardiomyopathy: Possible evidence of a primary atrial myopathy.

    Keane, Stephen / Fabre, Aurelie / Keane, David

    HeartRhythm case reports

    2021  Band 7, Heft 6, Seite(n) 413–417

    Sprache Englisch
    Erscheinungsdatum 2021-04-02
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2021.03.017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Cardiac MRI e-prime predicts myocardial late gadolinium enhancement and diastolic dysfunction in hypertrophic cardiomyopathy.

    O'Brien, Amy C / MacDermott, Roisin / Keane, Stephen / Ryan, David T / McVeigh, Niall / Durand, Rory / Ferre, Maria / Murphy, David J / Teekakirikul, Polakit / Keane, David / McDonald, Ken / Ledwidge, Mark / Dodd, Jonathan D

    European journal of radiology

    2022  Band 149, Seite(n) 110192

    Abstract: Background: Myocardial fibrosis leads to diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM).: Objectives: To evaluate a manual method of measuring mitral annular relaxation velocity (termed cardiac MRI e') as a measure of ... ...

    Abstract Background: Myocardial fibrosis leads to diastolic dysfunction in patients with hypertrophic cardiomyopathy (HCM).
    Objectives: To evaluate a manual method of measuring mitral annular relaxation velocity (termed cardiac MRI e') as a measure of diastolic dysfunction on routine cardiac MRI and its relationship with myocardial late-gadolinium enhancement (LGE) and feature tracking measures of diastolic dysfunction in patients with HCM.
    Methods: CMR e', feature tracking measures of diastolic function, left atrial, left ventricular (LV) parameters and LGE were retrospectively measured in 75 patients with HCM (mean age, 54.7 years ± 15.3, 54 men). Multivariate regression and partial Spearman correlations were performed.
    Results: Cardiac MRI e' measures correlated with LGE (r = 0.49, P < 0.001) and multiple feature tracking measures of diastolic function, adjusted for patient demographics, left atrial and left ventricular parameters. Cardiac MRI e' measures were independently predictive of LGE ≥ 10% (mean total cardiac MRI e': LGE < 10% vs LGE ≥ 10% was 3.5 cm/s vs. 1.7 cm/s, P < 0.001). Superior CMR e' had an AUC of 0.79 [95%CI 0.66-0.92, P < 0.0001]) in predicting patients with LGE ≥ 10% and a cutoff of 1.7 cm/s resulted in a sensitivity and specificity of 81.0% and 78.0% respectively.
    Conclusion: Cardiac MRI e' is a manual measure of LV diastolic dysfunction acquired on routine cardiac MRI without specialized software and is an independent predictor of LGE ≥ 10% and diastolic dysfunction in HCM.
    Mesh-Begriff(e) Cardiomyopathy, Hypertrophic/diagnostic imaging ; Contrast Media ; Fibrosis ; Gadolinium ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Retrospective Studies
    Chemische Substanzen Contrast Media ; Gadolinium (AU0V1LM3JT)
    Sprache Englisch
    Erscheinungsdatum 2022-02-03
    Erscheinungsland Ireland
    Dokumenttyp Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2022.110192
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: A Review of the Anatomical and Histological Attributes of the Left Atrial Appendage with Descriptive Pathological Examination of Morphology and Histology.

    Hensey, Mark / O'Neill, Louisa / Mahon, Ciara / Keane, Stephen / Fabre, Aurelie / Keane, David

    Journal of atrial fibrillation

    2018  Band 10, Heft 6, Seite(n) 1650

    Abstract: The left atrial appendage (LAA) has a key role in the embolic complications of atrial fibrillation (AF). It has been studied extensively, from recent interest in the thrombotic implications of various LAA morphologies to LAA occlusion and ablation. We ... ...

    Abstract The left atrial appendage (LAA) has a key role in the embolic complications of atrial fibrillation (AF). It has been studied extensively, from recent interest in the thrombotic implications of various LAA morphologies to LAA occlusion and ablation. We collected eleven post-mortem LAA samples for visual analysis, two were not included due to poor sample quality. On examination of the nine remaining samples, several common patterns of pectinate muscle orientation were noted. The LAA samples were noted to have a smooth circumferential neck of muscular tissue giving rise to a dominant singular smooth trunk of papillary muscle in 6 cases and two trunks in 3 cases. These trunks were either shallow (5 samples) or more muscular and raised (4 samples). Shallow trunks tended to be wider than the raised trunks and may even be circumferential (2 samples). The main trunk arborized to give off papillary muscle branches down to third or fourth order branches. The samples were visually assessed for the percentage of smooth papillary muscle versus non-papillary recesses and were found to have ≤50% smooth muscle in 3 samples, 50-75% in 3 samples and >75% in 3 samples. We performed histological analysis of further LAA samples collected during cardiac surgery in a parallel study. We identified a distinct pattern of myocyte orientation from the neck, mid-section and apical section of the LAA demonstrating arborization of myocyte fibers with minimal communication in distal segments of the LAA. We feel that this information may help understanding of the issues surrounding LAA ablation strategies.
    Sprache Englisch
    Erscheinungsdatum 2018-04-30
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2451936-4
    ISSN 1941-6911
    ISSN 1941-6911
    DOI 10.4022/jafib.1650
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch: Disaster movies

    Keane, Stephen

    the cinema of catastrophe

    (A Wallflower paperback ; Short cuts ; 6)

    2001  

    Verfasserangabe Stephen Keane
    Serientitel A Wallflower paperback
    Short cuts ; 6
    Sprache Englisch
    Umfang 133 p, ill, 21 cm
    Verlag Wallflower Press
    Erscheinungsort London u.a.
    Dokumenttyp Buch
    ISBN 1903364051 ; 9781903364055
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  6. Buch: Disaster movies

    Keane, Stephen

    the cinema of catastrophe

    (A Wallflower paperback ; Short cuts ; 6)

    2001  

    Verfasserangabe Stephen Keane
    Serientitel A Wallflower paperback
    Short cuts ; 6
    Sprache Englisch
    Umfang 133 p, ill, 21 cm
    Verlag Wallflower Press
    Erscheinungsort London u.a.
    Dokumenttyp Buch
    ISBN 1903364051 ; 9781903364055
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  7. Artikel ; Online: Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial.

    Sykes, Robert / Collison, Damien / Merkely, Bela / Kofoed, Klaus F / Donnelly, Patrick / Rodríguez-Palomares, José / Erglis, Andrejs / Veselka, Josef / Šakalytė, Gintarė / Ađić, Nada Čemerlić / Gutberlet, Matthias / Dodd, Jonathan D / Diez, Ignacio / Davis, Gershan / Zimmermann, Elke / Kępka, Cezary / Vidakovic, Radosav / Francone, Marco / Ilnicka-Suckiel, Małgorzata /
    Plank, Fabian / Knuuti, Juhani / Faria, Rita / Schröder, Stephen / Berry, Colin / Saba, Luca / Ruzsics, Balazs / Rieckmann, Nina / Kubiak, Christine / Hansen, Kristian Schultz / Müller-Nordhorn, Jacqueline / Maurovich-Horvat, Pál / Knudsen, Andreas D / Benedek, Imre / Orr, Clare / Valente, Filipa Xavier / Zvaigzne, Ligita / Horváth, Martin / Jankauskas, Antanas / Ađić, Filip / Woinke, Michael / Keane, Stephen / Lecumberri, Iñigo / Thwaite, Erica / Laule, Michael / Kruk, Mariusz / Zivanic, Aleksandra / Mancone, Massimo / Kuśmierz, Donata / Feuchtner, Gudrun / Pietilä, Mikko / Ribeiro, Vasco Gama / Drosch, Tanja / Delles, Christian / Porcu, Michele / Fisher, Michael / Bárány, Tamás / Sørum, Charlotte / Aurelian, Rosca / Kelly, Stephanie / Garcia Del Blanco, Bruno / Rubio, Ainhoa / Szilveszter, Bálint / Abdulla, Jawdat / Rodean, Ioana / Regan, Susan / Cuéllar Calabria, Hug / Vecsey-Nagy, Milán / Jurlander, Birgit / Hodas, Roxana / Feger, Sarah / Mohamed, Mahmoud / Serna-Higuita, Lina M / Neumann, Konrad / Dreger, Henryk / Rief, Matthias / Wieske, Viktoria / Ferencik, Maros / Estrella, Melanie / Bosserdt, Maria / Martus, Peter / Benedek, Theodora / Dewey, Marc

    Radiology

    2024  Band 310, Heft 2, Seite(n) e230591

    Abstract: Background Recent trials support the role of cardiac CT in the evaluation of symptomatic patients suspected of having coronary artery disease (CAD); however, body mass index (BMI) has been reported to negatively impact CT image quality. Purpose To ... ...

    Abstract Background Recent trials support the role of cardiac CT in the evaluation of symptomatic patients suspected of having coronary artery disease (CAD); however, body mass index (BMI) has been reported to negatively impact CT image quality. Purpose To compare initial use of CT versus invasive coronary angiography (ICA) on clinical outcomes in patients with stable chest pain stratified by BMI category. Materials and Methods This prospective study represents a prespecified BMI subgroup analysis of the multicenter Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial conducted between October 2015 and April 2019. Adult patients with stable chest pain and a CAD pretest probability of 10%-60% were randomly assigned to undergo initial CT or ICA. The primary end point was major adverse cardiovascular events (MACE), including cardiovascular death, nonfatal myocardial infarction, or stroke. The secondary end point was an expanded MACE composite, including transient ischemic attack, and major procedure-related complications. Competing risk analyses were performed using the Fine and Gray subdistribution Cox proportional hazard model to assess the impact of the relationship between BMI and initial management with CT or ICA on the study outcomes, whereas noncardiovascular death and unknown causes of death were considered competing risk events. Results Among the 3457 participants included, 831 (24.0%), 1358 (39.3%), and 1268 (36.7%) had a BMI of less than 25, between 25 and 30, and greater than 30 kg/m
    Mesh-Begriff(e) Adult ; Humans ; Coronary Artery Disease/diagnostic imaging ; Body Mass Index ; Coronary Angiography ; Patient Discharge ; Prospective Studies ; Chest Pain/diagnostic imaging
    Sprache Englisch
    Erscheinungsdatum 2024-02-13
    Erscheinungsland United States
    Dokumenttyp Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.230591
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Impact of smoking in patients with suspected coronary artery disease in the randomised DISCHARGE trial.

    Mancone, Massimo / Mézquita, Aldo J Vázquez / Birtolo, Lucia Ilaria / Maurovich-Horvat, Pal / Kofoed, Klaus F / Benedek, Theodora / Donnelly, Patrick / Rodriguez-Palomares, Jose / Erglis, Andrejs / Štěchovský, Cyril / Šakalytė, Gintare / Ađić, Nada Čemerlić / Gutberlet, Matthias / Diez, Ignacio / Davis, Gershan / Zimmermann, Elke / Kępka, Cezary / Vidakovic, Radosav / Francone, Marco /
    Ilnicka-Suckiel, Małgorzata / Plank, Fabian / Knuuti, Juhanni / Faria, Rita / Schröder, Stephen / Berry, Colin / Saba, Luca / Ruzsics, Balazs / Rieckmann, Nina / Kubiak, Christine / Hansen, Kristian Schultz / Müller-Nordhorn, Jaqueline / Merkely, Bela / Sigvardsen, Per E / Benedek, Imre / Orr, Clare / Valente, Filipa Xavier / Zvaigzne, Ligita / Suchánek, Vojtěch / Jankauskas, Antanas / Ađić, Filip / Woinke, Michael / Keane, Stephen / Lecumberri, Ignacio / Thwaite, Erica / Kruk, Mariusz / Jovanovic, Vladimir / Kuśmierz, Donata / Feuchtner, Gudren / Pietilä, Mikko / Ribeiro, Vasco Gama / Drosch, Tanja / Delles, Christian / Palmisano, Vitanio / Fisher, Michael / Drobni, Zsófia D / Kragelund, Charlotte / Aurelian, Rosca / Kelly, Stephanie / Del Blanco, Bruno Garcia / Rubio, Ainhoa / Boussoussou, Melinda / Hove, Jens D / Rodean, Ioana / Regan, Susan / Calabria, Hug Cuéllar / Becker, Dávid / Larsen, Linnea / Hodas, Roxana / Napp, Adriane E / Haase, Robert / Feger, Sarah / Mohamed, Mahmoud / Neumann, Konrad / Dreger, Henryk / Rief, Matthias / Wieske, Viktoria / Douglas, Pamela S / Estrella, Melanie / Bosserdt, Maria / Martus, Peter / Serna-Higuita, Lina M / Dodd, Jonathan D / Dewey, Marc

    European radiology

    2023  

    Abstract: Objectives: To investigate if the effect of cardiac computed tomography (CT) vs. invasive coronary angiography (ICA) on cardiovascular events differs based on smoking status.: Materials and methods: This pre-specified subgroup analysis of the ... ...

    Abstract Objectives: To investigate if the effect of cardiac computed tomography (CT) vs. invasive coronary angiography (ICA) on cardiovascular events differs based on smoking status.
    Materials and methods: This pre-specified subgroup analysis of the pragmatic, prospective, multicentre, randomised DISCHARGE trial (NCT02400229) involved 3561 patients with suspected coronary artery disease (CAD). The primary endpoint was major adverse cardiovascular events (MACE: cardiovascular death, non-fatal myocardial infarction, or stroke). Secondary endpoints included an expanded MACE composite (MACE, transient ischaemic attack, or major procedure-related complications).
    Results: Of 3445 randomised patients with smoking data (mean age 59.1 years + / - 9.7, 1151 men), at 3.5-year follow-up, the effect of CT vs. ICA on MACE was consistent across smoking groups (p for interaction = 0.98). The percutaneous coronary intervention rate was significantly lower with a CT-first strategy in smokers and former smokers (p = 0.01 for both). A CT-first strategy reduced the hazard of major procedure-related complications (HR: 0.21, 95% CI: 0.03, 0.81; p = 0.045) across smoking groups. In current smokers, the expanded MACE composite was lower in the CT- compared to the ICA-first strategy (2.3% (8) vs 6.0% (18), HR: 0.38; 95% CI: 0.17, 0.88). The rate of non-obstructive CAD was significantly higher in all three smoking groups in the CT-first strategy.
    Conclusion: For patients with stable chest pain referred for ICA, the clinical outcomes of CT were consistent across smoking status. The CT-first approach led to a higher detection rate of non-obstructive CAD and fewer major procedure-related complications in smokers.
    Clinical relevance statement: This pre-specified sub-analysis of the DISCHARGE trial confirms that a CT-first strategy in patients with stable chest pain referred for invasive coronary angiography with an intermediate pre-test probability of coronary artery disease is as effective as and safer than invasive coronary angiography, irrespective of smoking status.
    Trial registration: ClinicalTrials.gov NCT02400229.
    Key points: • No randomised studies have assessed smoking status on CT effectiveness in symptomatic patients referred for invasive coronary angiography. • A CT-first strategy results in comparable adverse events, fewer complications, and increased coronary artery disease detection, irrespective of smoking status. • A CT-first strategy is safe and effective for stable chest pain patients with intermediate pre-test probability for CAD, including never smokers.
    Sprache Englisch
    Erscheinungsdatum 2023-11-22
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-023-10355-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Comparative effectiveness of initial computed tomography and invasive coronary angiography in women and men with stable chest pain and suspected coronary artery disease: multicentre randomised trial.

    Kofoed, Klaus F / Bosserdt, Maria / Maurovich-Horvat, Pál / Rieckmann, Nina / Benedek, Theodora / Donnelly, Patrick / Rodriguez-Palomares, José / Erglis, Andrejs / Štěchovský, Cyril / Šakalytė, Gintarė / Ađić, Filip / Gutberlet, Matthias / Dodd, Jonathan D / Diez, Ignacio / Davis, Gershan / Zimmermann, Elke / Kępka, Cezary / Vidakovic, Radosav / Francone, Marco /
    Ilnicka-Suckiel, Małgorzata / Plank, Fabian / Knuuti, Juhani / Faria, Rita / Schröder, Stephen / Berry, Colin / Saba, Luca / Ruzsics, Balazs / Kubiak, Christine / Hansen, Kristian Schultz / Müller-Nordhorn, Jacqueline / Merkely, Bela / Jørgensen, Tem S / Benedek, Imre / Orr, Clare / Valente, Filipa Xavier / Zvaigzne, Ligita / Suchánek, Vojtěch / Zajančkauskienė, Laura / Čanković, Milenko / Woinke, Michael / Keane, Stephen / Lecumberri, Iñigo / Thwaite, Erica / Laule, Michael / Kruk, Mariusz / Neskovic, Aleksandar N / Mancone, Massimo / Kuśmierz, Donata / Feuchtner, Gudrun / Pietilä, Mikko / Ribeiro, Vasco Gama / Drosch, Tanja / Delles, Christian / Loi, Bruno / Fisher, Michael / Szilveszter, Bálint / Sigvardsen, Per E / Ratiu, Mihaela / Kelly, Stephanie / Garcia Del Blanco, Bruno / Rubio, Ainhoa / Drobni, Zsófia D / Kragelund, Charlotte / Rodean, Ioana / Regan, Susan / Calabria, Hug Cuéllar / Boussoussou, Melinda / Engstrøm, Thomas / Hodas, Roxana / Napp, Adriane E / Haase, Robert / Feger, Sarah / Mohamed, Mahmoud M A / Serna-Higuita, Lina M / Neumann, Konrad / Dreger, Henryk / Rief, Matthias / Wieske, Viktoria / Estrella, Melanie / Martus, Peter / Dewey, Marc

    BMJ (Clinical research ed.)

    2022  Band 379, Seite(n) e071133

    Abstract: Objective: To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women and men with stable chest pain suspected to be caused by coronary artery disease.: Design: Prospective, multicentre, randomised ... ...

    Abstract Objective: To assess the comparative effectiveness of computed tomography and invasive coronary angiography in women and men with stable chest pain suspected to be caused by coronary artery disease.
    Design: Prospective, multicentre, randomised pragmatic trial.
    Setting: Hospitals at 26 sites in 16 European countries.
    Participants: 2002 (56.2%) women and 1559 (43.8%) men (total of 3561 patients) with suspected coronary artery disease referred for invasive coronary angiography on the basis of stable chest pain and a pre-test probability of obstructive coronary artery disease of 10-60%.
    Intervention: Both women and men were randomised 1:1 (with stratification by gender and centre) to a strategy of either computed tomography or invasive coronary angiography as the initial diagnostic test (1019 and 983 women, and 789 and 770 men, respectively), and an intention-to-treat analysis was performed. Randomised allocation could not be blinded, but outcomes were assessed by investigators blinded to randomisation group.
    Main outcome measures: The primary endpoint was major adverse cardiovascular events (MACE; cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke). Key secondary endpoints were an expanded MACE composite (cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, transient ischaemic attack, or major procedure related complication) and major procedure related complications.
    Results: Follow-up at a median of 3.5 years was available in 98.9% (1979/2002) of women and in 99.0% (1544/1559) of men. No statistically significant gender interaction was found for MACE (P=0.29), the expanded MACE composite (P=0.45), or major procedure related complications (P=0.11). In both genders, the rate of MACE did not differ between the computed tomography and invasive coronary angiography groups. In men, the expanded MACE composite endpoint occurred less frequently in the computed tomography group than in the invasive coronary angiography group (22 (2.8%)
    Conclusion: This study found no evidence for a difference between women and men in the benefit of using computed tomography rather than invasive coronary angiography as the initial diagnostic test for the management of stable chest pain in patients with an intermediate pre-test probability of coronary artery disease. An initial computed tomography scan was associated with fewer major procedure related complications in women and a lower frequency of the expanded MACE composite in men.
    Trial registration: NCT02400229ClinicalTrials.gov NCT02400229.
    Mesh-Begriff(e) Female ; Humans ; Male ; Coronary Angiography/methods ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnostic imaging ; Prospective Studies ; Chest Pain/diagnostic imaging ; Chest Pain/etiology ; Tomography, X-Ray Computed ; Myocardial Infarction/diagnostic imaging ; Myocardial Infarction/epidemiology ; Stroke ; Computed Tomography Angiography ; Predictive Value of Tests
    Sprache Englisch
    Erscheinungsdatum 2022-10-19
    Erscheinungsland England
    Dokumenttyp Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj-2022-071133
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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