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Article ; Online: A case report of sodium azide-induced myopericarditis.

Tarabanis, Constantine / Banco, Darcy / Keller, Norma M / Bangalore, Sripal / Alviar, Carlos L

European heart journal. Case reports

2024 Volume 8, Issue 4, Page(s) ytae134

Abstract: Background: Sodium azide exposures are rare but can be lethal as the substance inhibits complex IV in the electron transport chain, blocking adenosine-triphosphate (ATP) synthesis. Sodium azide is mostly used as a propellant in vehicular airbags but is ... ...

Abstract	Background: Sodium azide exposures are rare but can be lethal as the substance inhibits complex IV in the electron transport chain, blocking adenosine-triphosphate (ATP) synthesis. Sodium azide is mostly used as a propellant in vehicular airbags but is also used in laboratory, pharmacy, and industrial settings. No known antidote exists and its cardiotoxic effects are poorly described in the literature. Case summary: We describe the case of a 31-year-old patient with major depressive disorder presenting with altered mental status after ingestion of an unknown amount of sodium azide. Although initially chest pain free, she developed pleuritic chest pain 48 h after ingestion. This was accompanied by new diffuse ST elevations on the electrocardiogram and serum troponin elevations concerning for myopericarditis. Treatment was pursued with a 14-day course of colchicine resulting in complete symptom resolution within 4 days of treatment initiation. The patient's transthoracic echocardiogram was only notable for a preserved left ventricular ejection fraction (LVEF). Discussion: Cardiac toxicity after sodium azide ingestion usually occurs days after ingestion and has been previously described in the forms of heart failure with reduced ejection fraction complicated by cardiogenic shock. We describe the first case of sodium azide-induced myopericarditis with a preserved LVEF treated with colchicine. Colchicine is an established treatment for pericarditis, but its inhibition of endocytosis, an ATP-dependent cellular function, could be mechanistically relevant to this case.
Language	English
Publishing date	2024-03-20
Publishing country	England
Document type	Case Reports
ISSN	2514-2119
ISSN (online)	2514-2119
DOI	10.1093/ehjcr/ytae134
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Article ; Online: Intracardiac Versus Transesophageal Echocardiography Guided Percutaneous Debulking of Tricuspid Endocarditis.

Zhang, Robert S / Bailey, Eric / Maqsood, Muhammad H / Harari, Rafael / Bernard, Samuel / Xia, Yuhe / Keller, Norma / Alviar, Carlos L / Bangalore, Sripal

The American journal of cardiology

2024 Volume 217, Page(s) 141–143

MeSH term(s)	Humans ; Echocardiography, Transesophageal ; Cytoreduction Surgical Procedures ; Endocarditis/diagnosis ; Endocarditis/surgery ; Heart ; Endocarditis, Bacterial/diagnosis ; Endocarditis, Bacterial/surgery
Language	English
Publishing date	2024-02-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2024.01.036
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Article ; Online: Protected Rotational Atherectomy and DK NanoCrush POT rePOT Technique With Dual Guiding Catheters for Unprotected Distal Left Main.

Bangalore, Sripal / Koshy, Linda / Keller, Norma / Thompson, Craig

JACC. Cardiovascular interventions

2020 Volume 13, Issue 21, Page(s) e191–e193

MeSH term(s)	Angioplasty, Balloon, Coronary ; Atherectomy, Coronary ; Catheterization ; Coronary Angiography ; Coronary Artery Disease/surgery ; Humans ; Treatment Outcome
Keywords	covid19
Language	English
Publishing date	2020-10-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2020.08.019
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Article ; Online: Dual-Guide Triple-Kiss Technique for Left Main Trifurcation.

Bangalore, Sripal / Alkhalil, Ahmad / Feit, Frederick / Keller, Norma / Thompson, Craig

JACC. Cardiovascular interventions

2021 Volume 14, Issue 12, Page(s) e139–e141

MeSH term(s)	Angioplasty, Balloon, Coronary ; Coronary Angiography ; Humans ; Treatment Outcome
Language	English
Publishing date	2021-05-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2021.03.067
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Article ; Online: Tricuspid valve vegetation debulking using the AngioVac system.

Bangalore, Sripal / Alviar, Carlos L / Vlahakis, Susan / Keller, Norma

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

2021 Volume 98, Issue 3, Page(s) E475–E477

Abstract: Tricuspid valve endocarditis with recurrent septic pulmonary emboli is an indication for surgery. We present the case of a 36-year old man with tricuspid valve endocarditis and septic pulmonary emboli with percutaneous extraction of the vegetation. We ... ...

Abstract	Tricuspid valve endocarditis with recurrent septic pulmonary emboli is an indication for surgery. We present the case of a 36-year old man with tricuspid valve endocarditis and septic pulmonary emboli with percutaneous extraction of the vegetation. We discuss the nuances of such an approach and the need for more evidence in the management of these complex patients.
MeSH term(s)	Adult ; Cytoreduction Surgical Procedures ; Endocarditis/diagnostic imaging ; Endocarditis/surgery ; Endocarditis, Bacterial/diagnostic imaging ; Endocarditis, Bacterial/surgery ; Humans ; Male ; Treatment Outcome ; Tricuspid Valve/diagnostic imaging ; Tricuspid Valve/surgery
Language	English
Publishing date	2021-02-10
Publishing country	United States
Document type	Case Reports
ZDB-ID	1459995-8
ISSN	1522-726X ; 1522-1946
ISSN (online)	1522-726X
ISSN	1522-1946
DOI	10.1002/ccd.29519
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Article ; Online: ST-Segment Elevation Myocardial Infarction in the Morbidly Obese: Use of the "Offloading" Technique.

Bangalore, Sripal / Koshy, Linda / Alviar, Carlos / Thompson, Craig / Keller, Norma

JACC. Cardiovascular interventions

2021 Volume 14, Issue 7, Page(s) 807–808

MeSH term(s)	Humans ; Myocardial Infarction/etiology ; Obesity, Morbid/complications ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/etiology ; ST Elevation Myocardial Infarction/therapy ; Treatment Outcome
Language	English
Publishing date	2021-03-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2452157-7
ISSN	1876-7605 ; 1936-8798
ISSN (online)	1876-7605
ISSN	1936-8798
DOI	10.1016/j.jcin.2020.12.017
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Article ; Online: Treatment of Purulent Pericarditis With Intrapericardial Alteplase.

Zhang, Robert S / Singh, Arushi / Alam, Usman / Grossman, Kelsey / Keller, Norma / Alviar, Carlos L / Bangalore, Sripal

Circulation. Cardiovascular imaging

2023 Volume 16, Issue 9, Page(s) e015412

MeSH term(s)	Humans ; Tissue Plasminogen Activator/therapeutic use ; Pericarditis/diagnostic imaging ; Pericarditis/drug therapy ; Pericardium/diagnostic imaging
Chemical Substances	Tissue Plasminogen Activator (EC 3.4.21.68)
Language	English
Publishing date	2023-07-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2435045-X
ISSN	1942-0080 ; 1941-9651
ISSN (online)	1942-0080
ISSN	1941-9651
DOI	10.1161/CIRCIMAGING.123.015412
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Zs.A 6743: Show issues

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Article ; Online: In-hospital Outcomes of Patients With and Without Previous Coronary Artery Bypass Graft Surgery Who Present With a Non-ST-Segment Elevation Myocardial Infarction.

Dhaduk, Nehal / Xia, Yuhe / Feit, Frederick / Mamas, Mamas / Alviar, Carlos / Keller, Norma / Rao, Sunil V / Bangalore, Sripal

The American journal of cardiology

2023 Volume 194, Page(s) 78–85

Abstract: The clinical course of patients with a previous coronary artery bypass graft surgery (CABG) presenting with non-ST-elevation myocardial infarction (NSTEMI) is not well defined. We aimed to compare the management and outcomes of patients with and without ... ...

Abstract	The clinical course of patients with a previous coronary artery bypass graft surgery (CABG) presenting with non-ST-elevation myocardial infarction (NSTEMI) is not well defined. We aimed to compare the management and outcomes of patients with and without previous CABG who present with an NSTEMI. Patients hospitalized with an NSTEMI between 2002 and 2018 were identified from the National Inpatient Sample. The baseline characteristics and outcomes of patients with and without a previous CABG were compared. The outcomes included the rates of invasive procedures (defined as coronary angiography, percutaneous coronary intervention [PCI], or CABG), and its individual components, and in-hospital mortality. A total of 1,445,545 cases of NSTEMI were found, of which 133,691 (9.3%) had a previous CABG. Patients with a previous CABG were older (72.4 vs 68.6 years, p <0.001), more likely men (68.8% vs 56.9%, p <0.001), and of White race (79.7% vs 74.8%, p <0.001). The previous CABG cohort had lower rates of invasive procedures (50.4% vs 65.6%, p <0.001), PCI (23.7% vs 32.0%, p <0.001), or CABG (1.2% vs 10.6%; p <0.001) in the unmatched analysis. The results were consistent in the propensity score-matched analysis with the previous CABG group less likely to receive any invasive procedures (odds ratio [OR] 0.48, 95% confidence interval [CI] 0.47 to 0.49), including coronary angiography (OR 0.54, 95% CI 0.53 to 0.55), PCI (OR 0.66, 95% CI 0.64 to 0.67), or repeat CABG (OR 0.11, 95% CI 0.10 to 0.12). Moreover, the risk of in-hospital mortality was higher in the previous CABG group (OR 1.15, 95% CI 1.10 to 1.21). In the subset of patients who were revascularized in both groups, this excess mortality was no longer observed (OR 0.82, 95% CI 0.66 to 1.03). In conclusion, a previous CABG in patients who present with NSTEMI is associated with lower rates of invasive procedures and revascularization and higher in-hospital mortality than patients without a previous CABG.
MeSH term(s)	Male ; Humans ; Non-ST Elevated Myocardial Infarction ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome ; Retrospective Studies ; Coronary Artery Bypass/methods
Language	English
Publishing date	2023-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	80014-4
ISSN	1879-1913 ; 0002-9149
ISSN (online)	1879-1913
ISSN	0002-9149
DOI	10.1016/j.amjcard.2023.02.013
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Article ; Online: Adult congenital heart disease care in a municipal public health system.

Tinsay, Maria Andrea Francesca M / Halpern, Dan G / Feinberg, Jodi L / Vorsanger, Matthew / Keller, Norma / Small, Adam J

Cardiology in the young

2023 Volume 34, Issue 4, Page(s) 859–864

Abstract: Specialty care is associated with improved outcomes for adults with adult CHD and must be extended to the underserved. A retrospective cohort study was performed to describe the provision of care to adult CHD patients in America's largest municipal ... ...

Abstract	Specialty care is associated with improved outcomes for adults with adult CHD and must be extended to the underserved. A retrospective cohort study was performed to describe the provision of care to adult CHD patients in America's largest municipal public health system including patient demographics, diagnostic and therapeutic procedures, and adherence to guideline-recommended surveillance. We identified 229 adult CHD patients aged >18 years through electronic medical records. The most common diagnoses were atrial septal defect, ventricular septal defect, patent ductus arteriosus, and valvular pulmonary stenosis. In total, 65% had moderate or greater anatomic complexity. A large number of patients were uninsured (45%), non-white (96%), and non-English speaking (44%). One hundred forty-six patients (64%) presented with unrepaired primary defects. Fifty eight patients underwent primary repair during the study period; 48 of those repairs were surgical and 10 were transcatheter. Collaboration with an affiliated Comprehensive Care Center was utilised for 28% of patients. A high proportion of patients received adult CHD speciality visits (78%), echocardiograms (66%), and electrocardiograms (56%) at the guideline-recommended frequency throughout the study period. There was no significant difference in the rate of adherence to guideline-recommended surveillance based on insurance status, race/ethnicity, or primary language status. The proportion of patients who had guideline-recommended adult CHD visits, echocardiograms, and electrocardiograms was significantly lower for those with more advanced physiological stages. These results can inform the provision of adult CHD care in other public health system settings.
MeSH term(s)	Humans ; Adult ; Heart Defects, Congenital/epidemiology ; Heart Defects, Congenital/therapy ; Heart Defects, Congenital/complications ; Retrospective Studies ; Public Health ; Heart Septal Defects, Atrial/complications ; Heart Septal Defects, Ventricular/surgery
Language	English
Publishing date	2023-11-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1078466-4
ISSN	1467-1107 ; 1047-9511
ISSN (online)	1467-1107
ISSN	1047-9511
DOI	10.1017/S1047951123003682
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Article ; Online: Relationship Between the Mixed Venous-to-Arterial Carbon Dioxide Gradient and Cardiac Index in Acute Pulmonary Embolism.

Yuriditsky, Eugene / Zhang, Robert S / Bakker, Jan / Horowitz, James M / Zhang, Peter / Bernard, Samuel / Greco, Allison A / Postelnicu, Radu / Mukherjee, Vikramjit / Hena, Kerry / Elbaum, Lindsay / Alviar, Carlos L / Keller, Norma M / Bangalore, Sripal

European heart journal. Acute cardiovascular care

2024

Abstract: Background: Among patients with acute pulmonary embolism (PE) undergoing mechanical thrombectomy, the cardiac index (CI) is frequently reduced even among those without clinically apparent shock. The purpose of this study was to describe the mixed venous- ...

Abstract	Background: Among patients with acute pulmonary embolism (PE) undergoing mechanical thrombectomy, the cardiac index (CI) is frequently reduced even among those without clinically apparent shock. The purpose of this study was to describe the mixed venous-to-arterial carbon dioxide gradient (CO2 gap), a surrogate of perfusion adequacy, among patients with acute PE undergoing mechanical thrombectomy. Methods: This was a single-center retrospective study of consecutive patients with PE undergoing mechanical thrombectomy and simultaneous pulmonary artery catheterization over a 3-year period. Results: Of 107 patients, 97 had simultaneous mixed venous and arterial blood gas measurements available. The CO2 gap was elevated (>6 mmHg) in 51% of the cohort and in 49% of patients with intermediate-risk PE. A reduced CI (≤2.2 L/min/m2) was associated with an increased odds (OR = 7.9; 95% CI 3.49-18.1, p < 0.001) for an elevated CO2 gap. There was an inverse relationship between CI and CO2 gap. For every 1 L/min/m2 decrease in the CI, the CO2 gap increased by 1.3 mmHg (p = 0.001). Among patients with an elevated baseline CO2 gap >6 mmHg, thrombectomy improved CO2 gap, CI, and mixed venous oxygen saturation. When the CO2 gap was dichotomized above and below 6, there was no difference in in-hospital mortality (9% vs. 0%; p = 0.10, HR: 1.24; 95% CI: 0.97-1.60; P = 0.085). Conclusions: Among patients with acute PE undergoing mechanical thrombectomy, the CO2 gap is abnormal in nearly 50% of patients and inversely related to CI. Further studies should examine the relationship between markers of perfusion and outcomes in this population to refine risk stratification.
Language	English
Publishing date	2024-03-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2663340-1
ISSN	2048-8734 ; 2048-8726
ISSN (online)	2048-8734
ISSN	2048-8726
DOI	10.1093/ehjacc/zuae031
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