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  1. Book ; Online: Engaging with small and medium agrifood enterprises to guide policy making

    Kelly, Siobhan / Ilie, Elena Teodora

    a qualitative research methodological guide

    (Sustainable markets, agribusinesses and rural transformations, SMART)

    2021  

    Institution FAO
    Author's details by Siobhan Kelly Elena Teodora Ilie ; Food and Agriculture Organization of the United Nations
    Series title Sustainable markets, agribusinesses and rural transformations, SMART
    Language English
    Size 1 Online-Ressource (vii, 67 Seiten)
    Publisher Food and Agriculture Organization of the United Nations
    Publishing place Rome
    Publishing country Italy
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020950918
    ISBN 978-92-5-134240-4 ; 92-5-134240-7
    DOI 10.4060/cb4179en
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Logistics, risks, and benefits of automated red blood cell exchange for patients with sickle cell disease.

    Kelly, Shannon

    Hematology. American Society of Hematology. Education Program

    2024  Volume 2023, Issue 1, Page(s) 646–652

    Abstract: Red blood cell (RBC) transfusions treat and prevent severe complications of sickle cell disease (SCD) and can be delivered as a simple or exchange transfusion. During an exchange, some of the patient's abnormal hemoglobin (Hb) S (HbS) RBCs are removed. ... ...

    Abstract Red blood cell (RBC) transfusions treat and prevent severe complications of sickle cell disease (SCD) and can be delivered as a simple or exchange transfusion. During an exchange, some of the patient's abnormal hemoglobin (Hb) S (HbS) RBCs are removed. An apheresis device can accomplish an automated RBC exchange, simultaneously removing patient's RBCs while returning other blood components along with normal RBCs. Automated RBC exchange is therefore an isovolemic transfusion that can efficiently decrease HbS RBCs while limiting iron loading and hyperviscosity. However, specialized equipment, trained personnel, appropriate vascular access, and increased RBC exposure are required compared to simple or manual RBC exchange. Therefore, risks and benefits must be balanced to make individualized decisions for patients with SCD who require transfusion.
    MeSH term(s) Humans ; Anemia, Sickle Cell/complications ; Erythrocytes ; Hemoglobin, Sickle ; Blood Transfusion ; Blood Component Removal
    Chemical Substances Hemoglobin, Sickle
    Language English
    Publishing date 2024-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2084287-9
    ISSN 1520-4383 ; 1520-4391
    ISSN (online) 1520-4383
    ISSN 1520-4391
    DOI 10.1182/hematology.2023000498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Burnout in Doctors Practising in Ireland Post Covid-19.

    Carr, P / Kelly, S

    Irish medical journal

    2023  Volume 116, Issue 4, Page(s) 761

    MeSH term(s) Humans ; Ireland/epidemiology ; COVID-19 ; Burnout, Psychological ; Burnout, Professional/epidemiology ; Physicians ; Surveys and Questionnaires
    Language English
    Publishing date 2023-04-20
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 193134-9
    ISSN 0332-3102 ; 0021-129X
    ISSN 0332-3102 ; 0021-129X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ten years (and counting) of Biology Open.

    Kelly, Steven

    Biology open

    2022  Volume 11, Issue 5

    MeSH term(s) Biology
    Language English
    Publishing date 2022-06-06
    Publishing country England
    Document type Editorial
    ZDB-ID 2632264-X
    ISSN 2046-6390 ; 2046-6390
    ISSN (online) 2046-6390
    ISSN 2046-6390
    DOI 10.1242/bio.059370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The quest for more food.

    Kelly, Steven

    Science (New York, N.Y.)

    2022  Volume 377, Issue 6604, Page(s) 370–371

    Abstract: Rice yield is increased by boosting nitrogen uptake and photosynthesis. ...

    Abstract Rice yield is increased by boosting nitrogen uptake and photosynthesis.
    MeSH term(s) Crop Production/methods ; Nitrogen/metabolism ; Oryza/growth & development ; Oryza/metabolism ; Photosynthesis
    Chemical Substances Nitrogen (N762921K75)
    Language English
    Publishing date 2022-07-21
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.add3882
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 27: Show issues Location:
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  6. Article ; Online: Reproductive justice must be considered in the scientific community.

    Ramirez, Kelly S

    Nature microbiology

    2022  Volume 7, Issue 3, Page(s) 352–353

    MeSH term(s) Reproduction ; Social Justice
    Language English
    Publishing date 2022-03-04
    Publishing country England
    Document type Journal Article
    ISSN 2058-5276
    ISSN (online) 2058-5276
    DOI 10.1038/s41564-022-01077-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Repeated boat noise exposure damages inner ear sensory hair cells and decreases hearing sensitivity in Atlantic croaker (Micropogonias undulatus).

    Badlowski, Gina A / Boyle, Kelly S

    The Journal of experimental biology

    2024  Volume 227, Issue 2

    Abstract: Anthropogenic noise is becoming a major underwater pollutant because of rapidly increasing boat traffic worldwide. But its impact on aquatic organisms remains largely unknown. Previous studies have focused mainly on high-frequency and impulsive noises (i. ...

    Abstract Anthropogenic noise is becoming a major underwater pollutant because of rapidly increasing boat traffic worldwide. But its impact on aquatic organisms remains largely unknown. Previous studies have focused mainly on high-frequency and impulsive noises (i.e. sonar); however, boat noise is more pervasive, continuous, and its highest intensity and component frequencies overlap the auditory bandwidth of most fishes. We assessed the impacts of boat noise on saccular sensory hair cell density and hearing thresholds of a soniferous species, Atlantic croaker (Micropogonias undulatus). In two laboratory experiments, individuals were subjected to simulated boat noise: a single 15-min exposure and 3 days of intermittent noise (simulating passing vessels). Immediately after both experiments, fish were either (1) tested for hearing sensitivity with auditory evoked potential (AEP) tests or (2) euthanized for fluorescent phalloidin and TUNEL labeling for hair cell density counts. Relative to controls, no differences were observed in auditory thresholds nor hair cell density between individuals subjected to a single 15-min noise exposure. However, fish from the 3-day experiment showed decreased sensory hair cell density, increased apoptotic cells, and higher hearing thresholds than control fish at 300, 800 and 1000 Hz. Our results demonstrate that impacts from boat noise depend upon the duration and frequency of exposure. For a species reliant on vocalization for communication, these impacts may hinder spawning success, increase predation risks and significantly alter the ecosystem.
    MeSH term(s) Animals ; Ships ; Ecosystem ; Hearing ; Perciformes/physiology ; Hair Cells, Auditory/physiology ; Fishes/physiology ; Auditory Threshold/physiology
    Language English
    Publishing date 2024-01-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 218085-6
    ISSN 1477-9145 ; 0022-0949
    ISSN (online) 1477-9145
    ISSN 0022-0949
    DOI 10.1242/jeb.245093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2629: Show issues Location:
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  8. Article ; Online: Early-career researchers: answering the most important scientific questions of our time.

    Kelly, Steven

    Biology open

    2021  Volume 10, Issue 11

    MeSH term(s) Biological Science Disciplines/trends ; Humans ; Intersectoral Collaboration ; Research Personnel/trends
    Language English
    Publishing date 2021-11-12
    Publishing country England
    Document type Editorial
    ZDB-ID 2632264-X
    ISSN 2046-6390 ; 2046-6390
    ISSN (online) 2046-6390
    ISSN 2046-6390
    DOI 10.1242/bio.059061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The economics of organellar gene loss and endosymbiotic gene transfer.

    Kelly, Steven

    Genome biology

    2021  Volume 22, Issue 1, Page(s) 345

    Abstract: Background: The endosymbiosis of the bacterial progenitors of the mitochondrion and the chloroplast are landmark events in the evolution of life on Earth. While both organelles have retained substantial proteomic and biochemical complexity, this ... ...

    Abstract Background: The endosymbiosis of the bacterial progenitors of the mitochondrion and the chloroplast are landmark events in the evolution of life on Earth. While both organelles have retained substantial proteomic and biochemical complexity, this complexity is not reflected in the content of their genomes. Instead, the organellar genomes encode fewer than 5% of the genes found in living relatives of their ancestors. While many of the 95% of missing organellar genes have been discarded, others have been transferred to the host nuclear genome through a process known as endosymbiotic gene transfer.
    Results: Here, we demonstrate that the difference in the per-cell copy number of the organellar and nuclear genomes presents an energetic incentive to the cell to either delete organellar genes or transfer them to the nuclear genome. We show that, for the majority of transferred organellar genes, the energy saved by nuclear transfer exceeds the costs incurred from importing the encoded protein into the organelle where it can provide its function. Finally, we show that the net energy saved by endosymbiotic gene transfer can constitute an appreciable proportion of total cellular energy budgets and is therefore sufficient to impart a selectable advantage to the cell.
    Conclusion: Thus, reduced cellular cost and improved energy efficiency likely played a role in the reductive evolution of mitochondrial and chloroplast genomes and the transfer of organellar genes to the nuclear genome.
    MeSH term(s) Arabidopsis/genetics ; Bacteria/genetics ; Cell Nucleus ; Chloroplasts ; Gene Transfer, Horizontal ; Genome, Chloroplast ; Genome, Mitochondrial ; Genome, Plant ; Host Microbial Interactions/genetics ; Mitochondria/genetics ; Proteomics ; Symbiosis/genetics
    Language English
    Publishing date 2021-12-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2040529-7
    ISSN 1474-760X ; 1474-760X
    ISSN (online) 1474-760X
    ISSN 1474-760X
    DOI 10.1186/s13059-021-02567-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Individual socioeconomic status is important but hard to measure.

    Kelly, Shona

    BMJ (Clinical research ed.)

    2021  Volume 372, Page(s) n174

    MeSH term(s) Humans ; Social Class ; Social Determinants of Health ; Social Factors ; Socioeconomic Factors
    Language English
    Publishing date 2021-01-22
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.n174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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