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  1. Book: Dermatopathologie

    Kempf, Werner Bernhard

    2015  

    Author's details Werner Kempf
    Keywords Skin Diseases / pathology ; Diagnosis, Differential ; Histopathologie bei Hautveränderungen ; Dermatologische Pathologie ; Histopathologie der Haut ; Dermatohistopathologie ; Dermatologische Histologie ; Hautkrankheit ; Histopathologie
    Subject Gewebepathologie ; Histologische Diagnose ; Histologische Pathologie ; Pathohistologie ; Pathologische Histologie ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten
    Language German
    Size XI, 328 S. : zahlr. Ill.
    Edition 3. Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT018669023
    ISBN 978-3-662-46407-6 ; 3-662-46407-1 ; 9783662464083 ; 366246408X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 2210 on loan 0 Vormerkungen

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  2. Book: Dermatopathologie

    Kempf, Werner

    2011  

    Author's details Werner Kempf
    Keywords Skin Diseases / pathology ; Diagnosis, Differential ; Hautkrankheit ; Histopathologie
    Subject Gewebepathologie ; Histologische Diagnose ; Histologische Pathologie ; Pathohistologie ; Pathologische Histologie ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten
    Language German
    Size XI, 304 S. : zahlr. Ill.
    Edition 2., erg. Aufl.
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note 1. Aufl. erschienen im Steinkopff-Verl., Darmstadt
    HBZ-ID HT016454173
    ISBN 978-3-642-12895-0 ; 3-642-12895-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2011 A 212 order for loan Magazin

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  3. Book ; Online ; E-Book: Atlas of clinical dermatopathology

    Burg, Günter / Kutzner, Heinz / Kempf, Werner / Feit, Josef / Sangueza, Omar

    infectious and parasitic dermatoses

    2021  

    Author's details editor-in-chief Günter Burg ; associate editors Heinz Kutzner, Werner Kempf, Josef Feit, Omar Sangueza
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xiii, 194 Seiten), Illustrationen, Diagramme
    Publisher Wiley Blackwell
    Publishing place Hoboken, NJ
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020931288
    ISBN 978-1-119-64708-9 ; 978-1-119-64705-8 ; 9781119647065 ; 1-119-64708-8 ; 1-119-64705-3 ; 1119647061
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Follicular T helper cells and cutaneous T-cell lymphomas.

    Kempf, Werner

    The British journal of dermatology

    2022  Volume 187, Issue 6, Page(s) 841–842

    MeSH term(s) Humans ; Lymphoma, T-Cell, Cutaneous/pathology ; T-Lymphocytes, Helper-Inducer/pathology ; Skin Neoplasms/pathology ; Lymphoma, Follicular/pathology
    Language English
    Publishing date 2022-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.21839
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui VI Zs.23: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Book: Dermatopathologie

    Kempf, Werner

    2007  

    Author's details W. Kempf
    Keywords Hautkrankheit ; Histopathologie
    Subject Gewebepathologie ; Histologische Diagnose ; Histologische Pathologie ; Pathohistologie ; Pathologische Histologie ; Dermatose ; Haut ; Hauterkrankung ; Hautkrankheiten
    Language German
    Size XII, 294 S. : zahlr. Ill.
    Publisher Steinkopff
    Publishing place Darmstadt
    Publishing country Germany
    Document type Book
    Note 2. Aufl. erschienen im Springer-Verl., Berlin
    HBZ-ID HT014899423
    ISBN 978-3-7985-1647-2 ; 3-7985-1647-2
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 A 3735 order for loan Magazin

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  6. Book ; Online ; E-Book: Dermatopathologie

    Kempf, Werner / Hantschke, Markus / Kutzner, Heinz

    2020  

    Author's details Werner Kempf, Markus Hantschke, Heinz Kutzner
    Keywords Dermatology ; Pathology ; Oncology
    Subject code 616.5
    Language German
    Size 1 Online-Ressource (XI, 349 Seiten)
    Edition 4. Auflage
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020394580
    ISBN 978-3-662-59240-3 ; 9783662592397 ; 3-662-59240-1 ; 3662592398
    DOI 10.1007/978-3-662-59240-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Article: A new era for cutaneous CD30-positive T-cell lymphoproliferative disorders.

    Kempf, Werner

    Seminars in diagnostic pathology

    2017  Volume 34, Issue 1, Page(s) 22–35

    Abstract: Cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ T-LPD) represent a spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL) and borderline lesions. They share the expression of CD30 as a ... ...

    Abstract Cutaneous CD30+ T-cell lymphoproliferative disorders (CD30+ T-LPD) represent a spectrum encompassing lymphomatoid papulosis (LyP), primary cutaneous anaplastic large-cell lymphoma (pcALCL) and borderline lesions. They share the expression of CD30 as a common phenotypic marker. They differ however in their clinical presentation, the histological features and clinical course. Moreover, LyP and PcALCL show numerous clinical, histological and phenotypic variants. Overlapping features of LyP and pcALCL with themselves and with other cutaneous and systemic lymphomas emphasize the importance of careful clinicopathologic correlation and staging in the diagnosis of CD30+ T-LPD. Furthermore, an increasing number of inflammatory and infectious skin disorders harboring medium-sized to large CD30+ cells have to be considered in the differential diagnosis. Whereas the expression of CD30 in cutaneous CD30+ T-LPD stands for a favourable prognosis, its expression in other cutaneous and systemic lymphomas has a divergent impact. The assessment of CD30 expression does not only provide prognostic information, but is of potential therapeutic relevance as CD30 can serve as a therapeutic target. This review focuses on the clinicopathological and phenotypic spectrum of CD30+ T-LPD, its differential diagnoses and the role of CD30 as a diagnostic, prognostic and therapeutic marker.
    MeSH term(s) Humans ; Ki-1 Antigen/metabolism ; Lymphoma, T-Cell/diagnosis ; Lymphoma, T-Cell/pathology ; Lymphoma, T-Cell/therapy ; Lymphomatoid Papulosis/diagnosis ; Lymphomatoid Papulosis/pathology ; Lymphomatoid Papulosis/therapy ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology ; Skin Neoplasms/therapy
    Chemical Substances Ki-1 Antigen
    Language English
    Publishing date 2017-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605834-6
    ISSN 1930-1111 ; 0740-2570
    ISSN (online) 1930-1111
    ISSN 0740-2570
    DOI 10.1053/j.semdp.2016.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1988: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Cutaneous T-cell lymphomas-An update 2021.

    Kempf, Werner / Mitteldorf, Christina

    Hematological oncology

    2021  Volume 39 Suppl 1, Page(s) 46–51

    Abstract: Cutaneous T-cell lymphomas (CTCL) represent the majority of primary cutaneous lymphomas (CL). Mycosis fungoides (MF) and cutaneous CD30+ lymphoproliferative disorders account for 80% of all CTCL. CTCL show overlapping histological features. Thus clinical- ...

    Abstract Cutaneous T-cell lymphomas (CTCL) represent the majority of primary cutaneous lymphomas (CL). Mycosis fungoides (MF) and cutaneous CD30+ lymphoproliferative disorders account for 80% of all CTCL. CTCL show overlapping histological features. Thus clinical-pathological correlation is of importance to achieve final diagnosis. MF shows a characteristic evolution with patches, plaques, and in a subset of patients (10%-20%) with tumors. Therapy is stage-adapted with skin-directed therapies such as UV-light therapies and corticosteroids in early disease stage (i.e., patch and limited plaque stage) and systemic therapies (retinoids, interferon, mono chemotherapy, targeted therapy) and/or radiation therapy (local or total skin beam electron) in advanced stages. Novel therapies include targeted therapy such as mogamulizumab (anti-CCR4) or brentuximab vedotin (anti-CD30) and histone deacetylase inhibitors. Considering the impact of targeted therapies, biomarkers such as CD30 are not only crucial for the diagnosis and correct classification of an individual lymphoma case, but also for therapy as they may represent therapeutic targets. In the recently revised WHO classification 2017 and the updated WHO-EORTC classification for CL 2018, primary cutaneous CD8+ acral T-cell lymphoma has been introduced as a new still provisional entity. It displays characteristic clinical, histological, and phenotypic features and exhibits an excellent prognosis. Rare, but aggressive CTCL include cutaneous primary cutaneous aggressive epidermotropic CD8-positive T-cell lymphoma and cutaneous gamma/delta T-cell lymphoma, which present with rapid onset of necrotic or ulcerated plaques and tumors. As they have a poor prognosis, treatment includes multiagent chemotherapy and hematopoietic stem cell transplantation.
    MeSH term(s) Humans ; Mycosis Fungoides/diagnosis ; Mycosis Fungoides/immunology ; Mycosis Fungoides/pathology ; Mycosis Fungoides/therapy ; Skin Neoplasms/diagnosis ; Skin Neoplasms/immunology ; Skin Neoplasms/pathology ; Skin Neoplasms/therapy
    Language English
    Publishing date 2021-06-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604884-5
    ISSN 1099-1069 ; 0278-0232
    ISSN (online) 1099-1069
    ISSN 0278-0232
    DOI 10.1002/hon.2850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1816: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Cutaneous Reactions after COVID-19 Vaccines: Analysis of the Clinical and Histopathological Spectrum-Case Series and Review of the Literature.

    Schmid, Ursina / Galambos, Jörg / Pfaltz, Katrin / Hegyi, Ivan / Courvoisier, Salomé / Kempf, Werner

    Dermatopathology (Basel, Switzerland)

    2024  Volume 11, Issue 1, Page(s) 130–141

    Abstract: 1) Background: Various cutaneous adverse drug reactions (ADRs) are observed with the implementation of mRNA COVID-19 vaccines. To gain insight into the clinicopathologic features, we analyzed the correlation of histological and clinical data in 48 ... ...

    Abstract (1) Background: Various cutaneous adverse drug reactions (ADRs) are observed with the implementation of mRNA COVID-19 vaccines. To gain insight into the clinicopathologic features, we analyzed the correlation of histological and clinical data in 48 patients with these ADRs. (2) Methods: Single-center retrospective study in patients with ADRs after mRNA COVID-19 vaccination (mRNA-1273 and BNT162b2 vaccines). (3) Results: Distant generalized ADRs prevailed (91%), often appearing clinically as spongiotic dermatitis or maculopapular exanthema. Histopathological analysis revealed spongiotic changes (46%) and dermal superficial perivascular predominantly lymphocytic infiltrates (17%). Eosinophils were found in 66% of biopsies, neutrophils in 29%, and plasma cells only in 8% of biopsies. Most ADRs occurred after the second vaccine dose (44%). Histologically spongiotic changes were associated with clinical features of spongiotic dermatitis in only 50% of patients and maculopapular exanthema in the remaining patients. ADRs represented an aggravation of preexisting skin disease in 23% of patients. ADRs regressed within 28 days or less in 53% of patients and persisted beyond a month in the remaining patients. (4) Conclusions: Our study demonstrates a diverse spectrum of generalized ADRs, revealing correlations between histology and clinical features but also instances of divergence. Interestingly, in about half of our patients, ADRs were self-limited, whereas ADRs extended beyond a month in the other half.
    Language English
    Publishing date 2024-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777118-0
    ISSN 2296-3529
    ISSN 2296-3529
    DOI 10.3390/dermatopathology11010013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Granulomatous pigmented purpuric dermatosis: Clinical and histopathologic findings in a series of nine cases.

    Matter, Alexandra Valeska / Kolm, Isabel / Kempf, Werner

    Journal of cutaneous pathology

    2022  Volume 49, Issue 7, Page(s) 597–603

    Abstract: We report the largest case series to date of granulomatous pigmented purpuric dermatosis (GPPD), a rare variant of pigmented purpuric dermatoses (PPD). GPPD can cause diagnostic difficulties as it can be mistaken clinically and histopathologically with ... ...

    Abstract We report the largest case series to date of granulomatous pigmented purpuric dermatosis (GPPD), a rare variant of pigmented purpuric dermatoses (PPD). GPPD can cause diagnostic difficulties as it can be mistaken clinically and histopathologically with numerous inflammatory and infectious dermatoses or even cutaneous T-cell lymphoma. We compared the histopathological findings of nine cases of GPPD with a control group consisting of 10 randomly selected PPD of other subtypes. GPPD seems to predominantly affect the lower extremities of adult male patients; a clear association with hyperlipidemia or other systemic conditions could not be confirmed. Histopathologically, GPPD is characterized by a dermal histiocyte-rich interstitial infiltrate with or without granuloma formation, thickened capillaries, extravasated erythrocytes, and/or hemosiderin deposits. In contrast to other forms of PPD, the inflammatory infiltrate of GPPD can extend to the mid or deep dermis and the admixed lymphocytic infiltrate is mainly composed of CD8+ T-cells.
    MeSH term(s) Adult ; Eczema ; Humans ; Keratosis ; Male ; Pigmentation Disorders/diagnosis ; Pigmentation Disorders/pathology ; Purpura/pathology
    Language English
    Publishing date 2022-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187078-6
    ISSN 1600-0560 ; 0303-6987
    ISSN (online) 1600-0560
    ISSN 0303-6987
    DOI 10.1111/cup.14224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1043: Show issues Location:
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