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  1. Article ; Online: Evolution of body mass index in children with type 1 diabetes mellitus.

    De Keukelaere, Marijke / Fieuws, Steffen / Reynaert, Nele / Vandoorne, Eva / Kerckhove, Kristel Vande / Asscherickx, Willeke / Casteels, Kristina

    European journal of pediatrics

    2018  Volume 177, Issue 11, Page(s) 1661–1666

    Abstract: The prevalence of childhood overweight and obesity has risen during the last 30 years, not only in children with type 2 diabetes, but also those with type 1 (T1D) and this is linked with an increased cardiovascular risk. A better understanding of weight ... ...

    Abstract The prevalence of childhood overweight and obesity has risen during the last 30 years, not only in children with type 2 diabetes, but also those with type 1 (T1D) and this is linked with an increased cardiovascular risk. A better understanding of weight patterns in the years after diagnosis of T1D is important to identify those children with a risk for excess weight gain and strategies to decrease this. We retrospectively analyzed data of all children with T1D followed at the department of Pediatric Endocrinology Leuven and diagnosed between 1991 and 2015. Data as age, sex, BMI, and Tanner score were extracted in 390 subjects. Standardized BMI (BMI SDS) in this study group using all data was 0.26. An increase in BMI SDS was seen as a function of time since diagnosis and age, both being independent predictors. Data comparison showed a significant stronger relation between BMI SDS and both time since diagnosis and age in girls. Children diagnosed after puberty showed a higher increase in BMI SDS.Conclusion: These longitudinal data suggest an important increase in BMI in children with T1D, both as a function of time since diagnosis and age, especially in girls. What is Known: • The prevalence of childhood overweight and obesity is risen during the last 30 years, in children with type 2 diabetes, but also those with type 1 diabetes. What is New: • Our study demonstrates with longitudinal data an increase in BMI in children with type 1 diabetes, especially girls. The increase in BMI SDS is seen as a function of time since diagnosis and age, both being independent predictors. Given the increased risk of metabolic syndrome and other complications in overweight children, special attention is needed to prevent this evolution.
    MeSH term(s) Adolescent ; Body Mass Index ; Body Weight ; Child ; Child, Preschool ; Diabetes Mellitus, Type 1/complications ; Female ; Humans ; Infant ; Longitudinal Studies ; Male ; Pediatric Obesity/epidemiology ; Pediatric Obesity/etiology ; Prevalence ; Retrospective Studies ; Time Factors
    Language English
    Publishing date 2018-08-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-018-3224-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Acute nutrition management in the prevention of metabolic illness: a practical approach with glucose polymers.

    Van Hove, Johan L K / Myers, Sommer / Kerckhove, Kristel Vande / Freehauf, Cynthia / Bernstein, Laurie

    Molecular genetics and metabolism

    2009  Volume 97, Issue 1, Page(s) 1–3

    MeSH term(s) Acyl-CoA Dehydrogenase/deficiency ; Adolescent ; Child ; Child, Preschool ; Glucose/therapeutic use ; Humans ; Infant ; Infant, Newborn ; Metabolic Diseases/drug therapy ; Metabolic Diseases/enzymology ; Metabolic Diseases/prevention & control ; Nutrition Therapy ; Polymers/therapeutic use
    Chemical Substances Polymers ; Acyl-CoA Dehydrogenase (EC 1.3.8.7) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2009-04-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1418518-0
    ISSN 1096-7206 ; 1096-7192
    ISSN (online) 1096-7206
    ISSN 1096-7192
    DOI 10.1016/j.ymgme.2009.03.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Consensus on the guidelines for the dietary management of classical galactosemia

    Kerckhove, Kristel Vande / Diels, Marianne / Vanhaesebrouck, Sigrid / Luyten, Karin / Pyck, Nancy / De Meyer, An / Van Driessche, Marleen / Robert, Martine / Corthouts, Karen / Caris, Ariane / Duchateau, Emilie / Dassy, Martine / Bihet, Genevieve

    European Society for Clinical Nutrition and Metabolism Clinical nutrition ESPEN. 2015 Feb., v. 10, no. 1

    2015  

    Abstract: Worldwide there is scientific discussion about the dietary management of galactosemia. The dietary management is very different in several countries among Europe, the US and Canada. The main points of discussion are related to the fact that i) despite a ... ...

    Abstract Worldwide there is scientific discussion about the dietary management of galactosemia. The dietary management is very different in several countries among Europe, the US and Canada. The main points of discussion are related to the fact that i) despite a strict diet some patients still have poor outcomes; ii) there is lack of scientific knowledge about the role of endogenous production of galactose on disease evolution, with or without diet. The aim of the current work was the creation of a Belgian consensus on dietary guidelines for the management of galactosemia.A step-wise approach was used to achieve a consensus, including: a workshop, a Delphi round, discussion groups and a round table of different Belgian experts.The consensus is an agreement between strict guidelines (strict limitation of fruits, vegetables and soybean products/French guidelines) and the more liberal guidelines (comparable with a diet free of lactose/guidelines of UK and the Netherlands). The consensus document consists of different modules, including the medical context, the theoretical background of dietary guidelines and the age-specific practical dietary guidelines.A Belgian consensus on the guidelines for the dietary management of classical galactosemia was developed despite the uncertainties of the efficacy and practical application of these guidelines. The final consensus is based on scientific knowledge and practical agreement among experts. In the future, regular revision of the guidelines is recommended and a uniform European guideline is desirable.
    Keywords Dietary Guidelines ; diet ; experts ; fruits ; galactose ; galactosemia ; guidelines ; lactose ; patients ; soybean products ; uncertainty ; vegetables ; Canada ; Netherlands ; United Kingdom ; United States
    Language English
    Dates of publication 2015-02
    Size p. e1-e4.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 2405-4577
    DOI 10.1016/j.clnme.2014.10.001
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Consensus on the guidelines for the dietary management of classical galactosemia.

    Kerckhove, Kristel Vande / Diels, Marianne / Vanhaesebrouck, Sigrid / Luyten, Karin / Pyck, Nancy / De Meyer, An / Van Driessche, Marleen / Robert, Martine / Corthouts, Karen / Caris, Ariane / Duchateau, Emilie / Dassy, Martine / Bihet, Genevieve

    Clinical nutrition ESPEN

    2015  Volume 10, Issue 1, Page(s) e1–e4

    Abstract: Background and aim: Worldwide there is scientific discussion about the dietary management of galactosemia. The dietary management is very different in several countries among Europe, the US and Canada. The main points of discussion are related to the ... ...

    Abstract Background and aim: Worldwide there is scientific discussion about the dietary management of galactosemia. The dietary management is very different in several countries among Europe, the US and Canada. The main points of discussion are related to the fact that i) despite a strict diet some patients still have poor outcomes; ii) there is lack of scientific knowledge about the role of endogenous production of galactose on disease evolution, with or without diet. The aim of the current work was the creation of a Belgian consensus on dietary guidelines for the management of galactosemia.
    Methods: A step-wise approach was used to achieve a consensus, including: a workshop, a Delphi round, discussion groups and a round table of different Belgian experts.
    Results: The consensus is an agreement between strict guidelines (strict limitation of fruits, vegetables and soybean products/French guidelines) and the more liberal guidelines (comparable with a diet free of lactose/guidelines of UK and the Netherlands). The consensus document consists of different modules, including the medical context, the theoretical background of dietary guidelines and the age-specific practical dietary guidelines.
    Conclusion: A Belgian consensus on the guidelines for the dietary management of classical galactosemia was developed despite the uncertainties of the efficacy and practical application of these guidelines. The final consensus is based on scientific knowledge and practical agreement among experts. In the future, regular revision of the guidelines is recommended and a uniform European guideline is desirable.
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Journal Article
    ISSN 2405-4577
    ISSN (online) 2405-4577
    DOI 10.1016/j.clnme.2014.10.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dietary practices in methylmalonic acidaemia: a European survey.

    Pinto, Alex / Evans, Sharon / Daly, Anne / Almeida, Manuela Ferreira / Assoun, Murielle / Belanger-Quintana, Amaya / Bernabei, Silvia Maria / Bollhalder, Sandra / Cassiman, David / Champion, Helena / Chan, Heidi / Corthouts, Karen / Dalmau, Jaime / Boer, Foekje de / Laet, Corinne De / Meyer, An de / Desloovere, An / Dianin, Alice / Dixon, Marjorie /
    Dokoupil, Katharina / Dubois, Sandrine / Eyskens, Francois / Faria, Ana / Fasan, Ilaria / Favre, Elisabeth / Feillet, François / Fekete, Anna / Gallo, Giorgia / Gingell, Cerys / Gribben, Joanna / Hansen, Kit Kaalund / Horst, Nienke Ter / Jankowski, Camille / Janssen-Regelink, Renske / Jones, Ilana / Jouault, Catherine / Kahrs, Gudrun Elise / Kok, Irene / Kowalik, Agnieszka / Laguerre, Catherine / Verge, Sandrine Le / Liguori, Alessandra / Lilje, Rina / Maddalon, Cornelia / Mayr, Doris / Meyer, Uta / Micciche, Avril / Och, Ulrike / Robert, Martine / Rocha, Júlio César / Rogozinski, Hazel / Rohde, Carmen / Ross, Kathleen / Saruggia, Isabelle / Schlune, Andrea / Singleton, Kath / Sjoqvist, Elisabeth / Skeath, Rachel / Stolen, Linn Helene / Terry, Allyson / Timmer, Corrie / Tomlinson, Lyndsey / Tooke, Alison / Kerckhove, Kristel Vande / van Dam, Esther / Hurk, Dorine van den / Ploeg, Liesbeth van der / van Driessche, Marleen / van Rijn, Margreet / Wegberg, Annemiek van / Vasconcelos, Carla / Vestergaard, Helle / Vitoria, Isidro / Webster, Diana / White, Fiona / White, Lucy / Zweers, Heidi / MacDonald, Anita

    Journal of pediatric endocrinology & metabolism : JPEM

    2019  Volume 33, Issue 1, Page(s) 147–155

    Abstract: Background The dietary management of methylmalonic acidaemia (MMA) is a low-protein diet providing sufficient energy to avoid catabolism and to limit production of methylmalonic acid. The goal is to achieve normal growth, good nutritional status and the ... ...

    Abstract Background The dietary management of methylmalonic acidaemia (MMA) is a low-protein diet providing sufficient energy to avoid catabolism and to limit production of methylmalonic acid. The goal is to achieve normal growth, good nutritional status and the maintenance of metabolic stability. Aim To describe the dietary management of patients with MMA across Europe. Methods A cross-sectional questionnaire was sent to European colleagues managing inherited metabolic disorders (IMDs) (n=53) with 27 questions about the nutritional management of organic acidaemias. Data were analysed by different age ranges (0-6 months; 7-12 months; 1-10 years; 11-16 years; >16 years). Results Questionnaires were returned from 53 centres. Twenty-five centres cared for 80 patients with MMA vitamin B12 responsive (MMAB12r) and 43 centres managed 215 patients with MMA vitamin B12 non-responsive (MMAB12nr). For MMAB12r patients, 44% of centres (n=11/25) prescribed natural protein below the World Health Organization/Food and Agriculture Organization/United Nations University (WHO/FAO/UNU) 2007 safe levels of protein intake in at least one age range. Precursor-free amino acids (PFAA) were prescribed by 40% of centres (10/25) caring for 36% (29/80) of all the patients. For MMAB12nr patients, 72% of centres (n=31/43) prescribed natural protein below the safe levels of protein intake (WHO/FAO/UNU 2007) in at least one age range. PFAA were prescribed by 77% of centres (n=33/43) managing 81% (n=174/215) of patients. In MMAB12nr patients, 90 (42%) required tube feeding: 25 via a nasogastric tube and 65 via a gastrostomy. Conclusions A high percentage of centres used PFAA in MMA patients together with a protein prescription that provided less than the safe levels of natural protein intake. However, there was inconsistent practices across Europe. Long-term efficacy studies are needed to study patient outcome when using PFAA with different severities of natural protein restrictions in patients with MMA to guide future practice.
    MeSH term(s) Adolescent ; Amino Acid Metabolism, Inborn Errors/diet therapy ; Amino Acid Metabolism, Inborn Errors/epidemiology ; Child ; Child, Preschool ; Cross-Sectional Studies ; Dietary Proteins/administration & dosage ; Europe/epidemiology ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Nutritional Support ; Surveys and Questionnaires/standards
    Chemical Substances Dietary Proteins
    Language English
    Publishing date 2019-12-16
    Publishing country Germany
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1231070-0
    ISSN 2191-0251 ; 0334-018X
    ISSN (online) 2191-0251
    ISSN 0334-018X
    DOI 10.1515/jpem-2019-0277
    Database MEDical Literature Analysis and Retrieval System OnLINE

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