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Article: Advancing quantitative evaluation of social determinants of mental health and intervention effects: the need for community risk assessments.

Keyes, Katherine M

World psychiatry : official journal of the World Psychiatric Association (WPA)

2024 Volume 23, Issue 1, Page(s) 96–97

Language	English
Publishing date	2024-01-12
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2236130-3
ISSN	2051-5545 ; 1723-8617
ISSN (online)	2051-5545
ISSN	1723-8617
DOI	10.1002/wps.21165
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Age, Period, and Cohort Effects in Alcohol Use in the United States in the 20th and 21st Centuries: Implications for the Coming Decades.

Keyes, Katherine M

Alcohol research : current reviews

2022 Volume 42, Issue 1, Page(s) 2

Abstract: This article is part of a Festschrift commemorating the 50th anniversary of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Established in 1970, first as part of the National Institute of Mental Health and later as an independent ... ...

Abstract	This article is part of a Festschrift commemorating the 50th anniversary of the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Established in 1970, first as part of the National Institute of Mental Health and later as an independent institute of the National Institutes of Health, NIAAA today is the world's largest funding agency for alcohol research. In addition to its own intramural research program, NIAAA supports the entire spectrum of innovative basic, translational, and clinical research to advance the diagnosis, prevention, and treatment of alcohol use disorder and alcohol-related problems. To celebrate the anniversary, NIAAA hosted a 2-day symposium, "Alcohol Across the Lifespan: 50 Years of Evidence-Based Diagnosis, Prevention, and Treatment Research," devoted to key topics within the field of alcohol research. This article is based on Dr. Keyes' presentation at the event. NIAAA Director George F. Koob, Ph.D., serves as editor of the Festschrift.
MeSH term(s)	Alcohol Drinking/epidemiology ; Alcohol-Related Disorders ; Alcoholism/epidemiology ; Cohort Effect ; Humans ; National Institute on Alcohol Abuse and Alcoholism (U.S.) ; United States/epidemiology
Language	English
Publishing date	2022-01-13
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2677485-9
ISSN	2169-4796 ; 1930-0573 ; 2168-3492 ; 0090-838X
ISSN (online)	2169-4796 ; 1930-0573
ISSN	2168-3492 ; 0090-838X
DOI	10.35946/arcr.v42.1.02
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Zs.B 2180: Show issues

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Article ; Online: Alcohol use in the older adult US population: Trends, causes, and consequences.

Keyes, Katherine M

Alcohol (Fayetteville, N.Y.)

2022 Volume 107, Page(s) 28–31

Abstract: Alcohol use, binge drinking, and alcohol use disorders have been increasing among older adults in the US population, including adults over 50 as well as adults over 65. Increases in consumption are sharper among women, and among those who use additional ... ...

Abstract	Alcohol use, binge drinking, and alcohol use disorders have been increasing among older adults in the US population, including adults over 50 as well as adults over 65. Increases in consumption are sharper among women, and among those who use additional substances such as cannabis, and those who are relatively healthy in older adulthood (i.e. those without multimorbidites). This commentary describes these trends as well as provides hypotheses, and the data underlying them, for both supply-side (alcohol marketing and messaging) and demand-side (healthier aging, increased financial stress) potential drivers of these increases. The need for additional resources and focus on older adult drinking is increasingly urgent, as alcohol-attributable deaths escalate among older adults in the United States.
MeSH term(s)	Humans ; Female ; United States/epidemiology ; Aged ; Alcoholism/epidemiology ; Alcohol Drinking/epidemiology ; Ethanol ; Binge Drinking/epidemiology
Chemical Substances	Ethanol (3K9958V90M)
Language	English
Publishing date	2022-05-31
Publishing country	United States
Document type	Editorial ; Research Support, N.I.H., Extramural
ZDB-ID	605912-0
ISSN	1873-6823 ; 0741-8329
ISSN (online)	1873-6823
ISSN	0741-8329
DOI	10.1016/j.alcohol.2022.05.005
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Zs.A 2011: Show issues

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Article ; Online: Measuring progress in publishing scholarship in Drug and Alcohol Dependence on race, ethnicity, and health equity in substance use disorder incidence and outcomes.

Keyes, Katherine M / Mauro, Pia M

Drug and alcohol dependence

2024 Volume 256, Page(s) 111111

MeSH term(s)	Humans ; Alcoholism/epidemiology ; Ethnicity ; Health Equity ; Fellowships and Scholarships ; Incidence
Language	English
Publishing date	2024-02-01
Publishing country	Ireland
Document type	Editorial
ZDB-ID	519918-9
ISSN	1879-0046 ; 0376-8716
ISSN (online)	1879-0046
ISSN	0376-8716
DOI	10.1016/j.drugalcdep.2024.111111
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Zs.A 1310: Show issues

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Book: Epidemiology matters

Keyes, Katherine M. / Galea, Sandro

a new introduction to methodological foundations

2014

Author's details	Katherine M. Keyes ; Sandro Galea
Keywords	Epidemiologic Methods ; Epidemiology ; Epidemiologic Research Design
Language	English
Size	239 S. : Ill., graph. Darst.
Publisher	Oxford Univ. Press
Publishing place	Oxford u.a.
Publishing country	Great Britain
Document type	Book
Note	Includes bibliographical references ; What is a population and what is population health? -- What is an exposure, what is a disease, and how do we measure them? -- What is a sample? -- Watching a sample, counting cases -- Are exposures associated with health indicators? -- What is a cause? -- Is the association causal, or are there alternative explanations? -- How do non-causal associations arise? -- How can we mitigate against non-causal associations in design and analysis? -- When do causes work together? -- Do the results matter beyond the study sample? -- How do we identify disease early to minimize its consequences? -- Conclusion : epidemiology and what matters most
HBZ-ID	HT018407158
ISBN	978-0-19-933124-6 ; 0-19-933124-3
Database	Catalogue ZB MED Medicine, Health

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2014 A 3745	available for loan (reading room)	Lesesaal EG

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Article ; Online: Major depression with co-occurring suicidal thoughts, plans, and attempts: An increasing mental health crisis in US adolescents, 2011-2020.

Lu, Wenhua / Keyes, Katherine M

Psychiatry research

2023 Volume 327, Page(s) 115352

Abstract: This study aimed to examine national trends and disparities in the prevalence and treatment of adolescent 12-month major depressive episode (MDE) with co-occurring suicidal thoughts, plans, and attempts. Publicly available data for adolescents aged 12-17 ...

Abstract	This study aimed to examine national trends and disparities in the prevalence and treatment of adolescent 12-month major depressive episode (MDE) with co-occurring suicidal thoughts, plans, and attempts. Publicly available data for adolescents aged 12-17 in the 2011-2020 National Survey on Drug Use and Health were analyzed. Bivariate and multivariable logistic regression analyses were conducted. In 2011, 4.6%, 2.1%, and 1.7% of adolescents had 12-month MDE with co-occurring suicidal thoughts, plans, and attempts, and the prevalence increased steadily to 9.8%, 5.3%, and 3.5% in 2019, respectively. In 2011, 45% of adolescents with MDE and suicidal thoughts received any mental health treatment, and the prevalence increased slightly to 46.6% in 2019. Meanwhile, the prevalence of treatment use among adolescents with MDE and suicidal plans remained stable at below 54%. Lastly, the prevalence of treatment use increased significantly from 53.6% in 2011 to 60.8% in 2019 among those with MDE and suicidal attempts. Continued high prevalence and low treatment use were observed in 2020. Disparities in treatment use were found in older adolescents, adolescents without insurance, Hispanics, and Asians. Concerted efforts are needed to prioritize evidence-based interventions, enhance outreach to high-risk groups, and expand service provisions to underserved adolescents.
MeSH term(s)	Humans ; Adolescent ; Suicidal Ideation ; Depressive Disorder, Major/epidemiology ; Depressive Disorder, Major/therapy ; Depressive Disorder, Major/psychology ; Suicide, Attempted/psychology ; Mental Health ; Depression/psychology ; Prevalence
Language	English
Publishing date	2023-07-17
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2023.115352
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Zs.A 1541: Show issues

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Article ; Online: Hallucinogen use among young adults ages 19-30 in the United States: Changes from 2018 to 2021.

Keyes, Katherine M / Patrick, Megan E

Addiction (Abingdon, England)

2023 Volume 118, Issue 12, Page(s) 2449–2454

Abstract: Background and aims: Given the shifting landscape of hallucinogen use, particularly with increased therapeutic use, understanding current changes in use is a necessary part of examining the potential risk hallucinogens pose to vulnerable populations, ... ...

Abstract	Background and aims: Given the shifting landscape of hallucinogen use, particularly with increased therapeutic use, understanding current changes in use is a necessary part of examining the potential risk hallucinogens pose to vulnerable populations, such as young adults. This study aimed to measure hallucinogen use among young adults aged 19-30 years from 2018 to 2021. Design, setting and participants: This was a longitudinal cohort study among young adults aged 19-30 years from the US general population, interviewed between 2018 and 2021. Participants comprised 11 304 unique respondents, with an average number of follow-ups of 1.46 (standard deviation = 0.50). Of the observed data points, 51.9% were among females. Measurements: We examined past 12-month self-reported use of lysergic acid diethylamide (LSD), as well as hallucinogens besides LSD (e.g. psilocybin), monitoring any use as well as frequency, overall and by sex. Findings: From 2018 to 2021, past 12-month use of LSD among young adults in the US remained relatively unchanged, from 3.7% [95% confidence interval (CI) = 3.1-4.3] in 2018 to 4.2% in 2021 (95% CI = 3.4-5.0). Non-LSD hallucinogen [e.g. 'shrooms', psilocybin or PCP (phenylcyclohexyl piperidine)] use, however, increased in prevalence from 3.4% (95% CI = 2.8-4.1) to 6.6% from 2018 to 2021 (95% CI = 5.5-7.6). Across years, the odds of non-LSD use were higher for males [odds ratio (OR) = 1.86, 95% CI = 1.52-2.26] and lower for black than white participants (OR = 0.29, 95% CI = 0.19-0.47) and those without a college-educated parent (OR = 0.80, 95% CI = 0.64-0.99). Demographic disparities were similar for LSD use. Conclusion: Prevalence of past-year use non-lysergic acid diethylamide (LSD) hallucinogen was twice as high in 2021 as in 2018 among US young adults. Correlates of non-LSD hallucinogen use included being male, white and from higher socio-economic status backgrounds.
MeSH term(s)	Female ; Humans ; Male ; Young Adult ; United States/epidemiology ; Hallucinogens ; Lysergic Acid Diethylamide ; Psilocybin ; Longitudinal Studies ; Prevalence
Chemical Substances	Hallucinogens ; Lysergic Acid Diethylamide (8NA5SWF92O) ; Psilocybin (2RV7212BP0)
Language	English
Publishing date	2023-06-07
Publishing country	England
Document type	Journal Article
ZDB-ID	1141051-6
ISSN	1360-0443 ; 0965-2140
ISSN (online)	1360-0443
ISSN	0965-2140
DOI	10.1111/add.16259
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Zs.B 551: Show issues

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Article ; Online: Annual Research Review: Sex, gender, and internalizing conditions among adolescents in the 21st century - trends, causes, consequences.

Keyes, Katherine M / Platt, Jonathan M

Journal of child psychology and psychiatry, and allied disciplines

2023 Volume 65, Issue 4, Page(s) 384–407

Abstract: Internalizing conditions of psychopathology include depressive and anxiety disorders; they most often onset in adolescence, are relatively common, and contribute to significant population morbidity and mortality. In this research review, we present the ... ...

Abstract	Internalizing conditions of psychopathology include depressive and anxiety disorders; they most often onset in adolescence, are relatively common, and contribute to significant population morbidity and mortality. In this research review, we present the evidence that internalizing conditions, including depression and anxiety, as well as psychological distress, suicidal thoughts and self-harm, and fatal suicide, are considerably increasing in adolescent populations across many countries. Evidence indicates that increases are currently greatest in female adolescents. We present an epidemiological framework for evaluating the causes of these increases, and synthesize research on whether several established risk factors (e.g., age of pubertal transition and stressful life events) and novel risk factors (e.g., digital technology and social media) meet conditions necessary to be plausible causes of increases in adolescent internalizing conditions. We conclude that there are a multitude of potential causes of increases in adolescent internalizing conditions, outline evidence gaps including the lack of research on nonbinary and gender nonconforming populations, and recommend necessary prevention and intervention foci from a clinical and public health perspective.
MeSH term(s)	Humans ; Female ; Adolescent ; Anxiety/psychology ; Anxiety Disorders/epidemiology ; Anxiety Disorders/etiology ; Anxiety Disorders/psychology ; Gender Identity ; Risk Factors ; Psychopathology ; Depression/epidemiology
Language	English
Publishing date	2023-07-17
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	218136-8
ISSN	1469-7610 ; 0021-9630 ; 0373-8086
ISSN (online)	1469-7610
ISSN	0021-9630 ; 0373-8086
DOI	10.1111/jcpp.13864
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Article ; Online: Racial inequities in homicide rates and homicide methods among Black and White women aged 25-44 years in the USA, 1999-2020: a cross-sectional time series study.

Waller, Bernadine Y / Joseph, Victoria A / Keyes, Katherine M

Lancet (London, England)

2024 Volume 403, Issue 10430, Page(s) 935–945

Abstract: Background: In the USA, Black women aged 25-44 years are disproportionately murdered compared with their White counterparts. Despite ongoing efforts to reduce racial and structural inequities, the result of these efforts remains unclear, particularly in ...

Abstract	Background: In the USA, Black women aged 25-44 years are disproportionately murdered compared with their White counterparts. Despite ongoing efforts to reduce racial and structural inequities, the result of these efforts remains unclear, particularly in light of the COVID-19 pandemic. Methods: This study examined a cross-sectional time series of homicide death rates, by race, from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research system. We included data for women aged 25-44 years between 1999 and 2020 among 30 states in the USA. Homicide death was classified using underlying cause and multiple cause of death codes; mortality rates were calculated per 100 000 based on US Census Bureau population sizes. Homicide methods were classified as firearm, cutting or piercing, and other. Firearm homicides were compared with other homicides with logistic regression including covariates of race, time, and their interaction. We report odds ratios and 95% CIs. Findings: In 2020, the homicide rate among Black women was 11·6 per 100 000, compared with 3 per 100 000 among White women. This inequity has persisted over time and is virtually unchanged since 1999. Homicide inequities vary across US states; in 11 states, racial inequities have increased since 1999. The racial inequity was greatest in Wisconsin, where in 2019-20, Black women aged 25-44 years were 20 times more likely to die by homicide than White women. Homicide by firearm is increasing in frequency; women in the USA had 2·44 (95% CI 2·14-2·78) times the odds of homicide involving firearms in 2019-20 compared with 1999-2003. Firearm homicide deaths are disproportionately concentrated among Black women in every region in the USA. Interpretation: Our findings suggest that there is an urgent need to address homicide inequities among Black and White women in the USA. Enacting federal legislation that reduces gun access is a crucial step. Policy makers must address long-standing structural factors that underpin elevated gun violence by implementing sustainable wealth-building opportunities; developing desegregated, mixed income and affordable housing; and increasing green spaces in communities where Black women largely reside. Funding: National Institute of Mental Health of the National Institutes of Health.
MeSH term(s)	United States/epidemiology ; Humans ; Female ; Homicide ; Suicide ; Time Factors ; Cross-Sectional Studies ; Pandemics ; White ; Firearms
Language	English
Publishing date	2024-02-08
Publishing country	England
Document type	Journal Article
ZDB-ID	3306-6
ISSN	1474-547X ; 0023-7507 ; 0140-6736
ISSN (online)	1474-547X
ISSN	0023-7507 ; 0140-6736
DOI	10.1016/S0140-6736(23)02279-1
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Zs.MG 94: Show issues

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Article ; Online: Prevalence of addiction in chronic pain: reanalysis of Vowles et al., 2015.

Keyes, Katherine M / Rutherford, Caroline

Pain

2022 Volume 163, Issue 5, Page(s) e693–e695

MeSH term(s)	Behavior, Addictive ; Chronic Pain/epidemiology ; Humans ; Prevalence
Language	English
Publishing date	2022-04-15
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	193153-2
ISSN	1872-6623 ; 0304-3959
ISSN (online)	1872-6623
ISSN	0304-3959
DOI	10.1097/j.pain.0000000000002573
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