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  1. AU="Khalilzad, Mohammad"
  2. AU="Safrida Safrida"
  3. AU="Sheridan, Krystal"
  4. AU="Spencer, Sandra"
  5. AU="Ikhapoh, Izuagie"
  6. AU="Jabeen, Nyla"
  7. AU="Elaine Mary Cowan"
  8. AU="Marcos Federico Pascuali"
  9. AU="Shi, Zhuqing"
  10. AU="Bernard Rosner"
  11. AU="van de Schoor, F."
  12. AU="Strzelecki, Antoine"
  13. AU=Cheung P Y
  14. AU="Arima, Tetsuhiko"
  15. AU="José Del Castillo Diego, Julio"
  16. AU="Han, Shujie"
  17. AU="Hernandez-Garcia, Elena"
  18. AU="Mansfield, Sara A"
  19. AU="Igarashi, Miyako"
  20. AU="Eloisa Romano"

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  1. Artikel ; Online: Roles of Mesenchymal Stem Cells in Breast Cancer Therapy: Engineered Stem Cells and Exosomal Cell-Free Based Therapy.

    Fath, Mohsen Karami / Zadian, Seyed Sajjad / Torbati, Samaneh Mohammad Bagherzadeh / Saqagandomabadi, Vahid / Afshar, Omid Yousefi / Khalilzad, Mohammad / Abedi, Sara / Moliani, Afshin / Barati, Ghasem

    Current molecular medicine

    2024  

    Abstract: Breast cancer has a high prevalence among women, with a high mortality rate. The number of people who suffer from breast cancer disease is increasing, whereas metastatic cancers are mostly incurable, and existing therapies have unfavorable side effects. ... ...

    Abstract Breast cancer has a high prevalence among women, with a high mortality rate. The number of people who suffer from breast cancer disease is increasing, whereas metastatic cancers are mostly incurable, and existing therapies have unfavorable side effects. For an extended duration, scientists have dedicated their efforts to exploring the potential of mesenchymal stem cells (MSCs) for the treatment of metastatic cancers, including breast cancer. MSCs could be genetically engineered to boost their anticancer potency. Furthermore, MSCs can transport oncolytic viruses, suicide genes, and anticancer medicines to tumors. Extracellular vesicles (EVs) are MSC products that have attracted scientist's attention as a cell-free treatment. This study narratively reviews the current state of knowledge on engineered MSCs and their EVs as promising treatments for breast cancer.
    Sprache Englisch
    Erscheinungsdatum 2024-01-24
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2064873-X
    ISSN 1875-5666 ; 1566-5240
    ISSN (online) 1875-5666
    ISSN 1566-5240
    DOI 10.2174/0115665240274818231207054037
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: The therapeutic effect of MSCs and their extracellular vesicles on neuroblastoma.

    Karami Fath, Mohsen / Bagherzadeh Torbati, Samaneh Mohammad / Saqagandomabadi, Vahid / Yousefi Afshar, Omid / Khalilzad, Mohammad / Abedi, Sara / Moliani, Afshin / Daneshdoust, Danyal / Barati, Ghasem

    Progress in biophysics and molecular biology

    2024  Band 187, Seite(n) 51–60

    Abstract: Neuroblastoma is a common inflammatory-related cancer during infancy. Standard treatment modalities including surgical interventions, high-dose chemotherapy, radiotherapy, and immunotherapy are not able to increase survival rate and reduce tumor relapse ... ...

    Abstract Neuroblastoma is a common inflammatory-related cancer during infancy. Standard treatment modalities including surgical interventions, high-dose chemotherapy, radiotherapy, and immunotherapy are not able to increase survival rate and reduce tumor relapse in high-risk patients. Mesenchymal stem cells (MSCs) are known for their tumor-targeting and immunomodulating properties. MSCs could be engineered to express anticancer agents (i.e., growth factors, cytokines, pro-apoptotic agents) or deliver oncolytic viruses in the tumor microenvironment. As many functions of MSCs are mediated through their secretome, researchers have tried to use extracellular vesicles (EVs) from MSCs for targeted therapy of neuroblastoma. Here, we reviewed the studies to figure out whether the use of MSCs could be worthwhile in neuroblastoma therapy or not. Native MSCs have shown a promoting or inhibiting role in cancers including neuroblastoma. Therefore, MSCs are proposed as a vehicle to deliver anticancer agents such as oncolytic viruses to the neuroblastoma tumor microenvironment. Although modified MSCs or their EVs have been shown to suppress the tumorigenesis of neuroblastoma, further pre-clinical and clinical studies are required to come to a conclusion.
    Mesh-Begriff(e) Humans ; Oncolytic Viruses ; Neuroblastoma/therapy ; Neuroblastoma/metabolism ; Neuroblastoma/pathology ; Mesenchymal Stem Cells/metabolism ; Antineoplastic Agents ; Extracellular Vesicles/metabolism ; Extracellular Vesicles/pathology ; Tumor Microenvironment
    Chemische Substanzen Antineoplastic Agents
    Sprache Englisch
    Erscheinungsdatum 2024-02-17
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 209302-9
    ISSN 1873-1732 ; 0079-6107
    ISSN (online) 1873-1732
    ISSN 0079-6107
    DOI 10.1016/j.pbiomolbio.2024.02.004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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    Verfügbar in ZB MED Köln/Königswinter

    Uc I Zs.281: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Artikel: The implementation of the nursing process in lower-income countries: An integrative review.

    Lotfi, Mojgan / Zamanzadeh, Vahid / Valizadeh, Leila / Khajehgoodari, Mohammad / Ebrahimpour Rezaei, Mehdi / Khalilzad, Mohammad Amin

    Nursing open

    2019  Band 7, Heft 1, Seite(n) 42–57

    Abstract: Aims: This review study aimed to investigate the strategies for implementing the nursing process in the clinical practice and the assessment of the implementation rate of this process in clinical settings of lower-income countries.: Design: An ... ...

    Abstract Aims: This review study aimed to investigate the strategies for implementing the nursing process in the clinical practice and the assessment of the implementation rate of this process in clinical settings of lower-income countries.
    Design: An integrative review.
    Method: The search was conducted of EMBASE, MEDLINE, CINAHL, Scopus and ISI databases from 1975-July 2018. Following the formation of the research team, two researchers independently selected the eligible studies; finally, 39 articles were approved by the research team for this study.
    Results: The researchers identified three themes: Effects of implementing the NP in clinical settings, Development and application of electronic software in the NP and Factors affecting the implementation of the NP. This review revealed that nurses and nursing managers in hospitals are interested in implementing the nursing process in the form of widely and continuously. But the necessary infrastructure, such as manpower, electronically or manually tools, has not yet been provided, and the implementation of the nursing process is done either imperfectly or not done.
    Mesh-Begriff(e) Humans ; Nurse Administrators ; Nursing Process
    Sprache Englisch
    Erscheinungsdatum 2019-11-01
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2809556-X
    ISSN 2054-1058
    ISSN 2054-1058
    DOI 10.1002/nop2.410
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Development of nursing care guideline for burned hands.

    Lotfi, Mojgan / Mirza Aghazadeh, Ahmad / Davami, Babak / Khajehgoodari, Mohammad / Aziz Karkan, Hanieh / Khalilzad, Mohammad Amin

    Nursing open

    2020  Band 7, Heft 4, Seite(n) 907–927

    Abstract: Aim: To develop an evidence-based guideline to care for hand-burned patients.: Design: An integrative review.: Method: The search was conducted of EMBASE, PubMed, Web of Science, SCOPUS, Clinical Key, Iranmedex, Magiran, Scientific Information ... ...

    Abstract Aim: To develop an evidence-based guideline to care for hand-burned patients.
    Design: An integrative review.
    Method: The search was conducted of EMBASE, PubMed, Web of Science, SCOPUS, Clinical Key, Iranmedex, Magiran, Scientific Information Database (SID), Cochran, CINAHL and Google Scholar databases from January 2000-August 2019. Following the formation of the research team, two researchers independently selected the eligible studies. The initial search resulted in 2,230 records; ultimately, 40 articles were identified to be the review after screening the records based on the study's inclusion and exclusion criteria. Quality of selected studies was evaluated with the MMAT method.
    Results: Data syntheses of selected studies, coded by highlighting the relevant parts of the text, and assigning code words to these areas were done. Following this, a constant comparison was used to develop categories by combining codes. Finally, hand burns nursing care guideline was developed by categorizing descriptive themes in two main phases.
    Conclusion: This review results have shown that evidence-based guidelines present high-quality recommendations for the healthcare team, which improves the quality of clinical care. Due to a lack of established guidelines in our context, it seems to be helpful to use evidence-based guidelines in managing burned hands.
    Mesh-Begriff(e) Burns/therapy ; Databases, Factual ; Hand Injuries/therapy ; Humans ; Nursing Care ; Patient Care Team
    Sprache Englisch
    Erscheinungsdatum 2020-03-20
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2809556-X
    ISSN 2054-1058
    ISSN 2054-1058
    DOI 10.1002/nop2.475
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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