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  1. Article ; Online: Correction to: Faintly tired: a systematic review of fatigue in patients with orthostatic syncope.

    Wu, Ryan E Y / Khan, Farhaan M / Hockin, Brooke C D / Lobban, Trudie C A / Sanatani, Shubhayan / Claydon, Victoria E

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 6, Page(s) 533

    Language English
    Publishing date 2022-09-20
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00886-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Faintly tired: a systematic review of fatigue in patients with orthostatic syncope.

    Wu, Ryan E Y / Khan, Farhaan M / Hockin, Brooke C D / Lobban, Trudie C A / Sanatani, Shubhayan / Claydon, Victoria E

    Clinical autonomic research : official journal of the Clinical Autonomic Research Society

    2022  Volume 32, Issue 3, Page(s) 185–203

    Abstract: Background: Orthostatic syncope (transient loss of conscious when standing-fainting) is common and negatively impacts quality of life. Many patients with syncope report experiencing fatigue, sometimes with "brain fog", which may further impact their ... ...

    Abstract Background: Orthostatic syncope (transient loss of conscious when standing-fainting) is common and negatively impacts quality of life. Many patients with syncope report experiencing fatigue, sometimes with "brain fog", which may further impact their quality of life, but the incidence and severity of fatigue in patients with syncope remain unclear. In this systematic review, we report evidence on the associations between fatigue and conditions of orthostatic syncope.
    Methods: We performed a comprehensive literature search of four academic databases to identify articles that evaluated the association between orthostatic syncope [postural orthostatic tachycardia syndrome (POTS), vasovagal syncope (VVS), orthostatic hypotension (OH)] and fatigue. Studies were independently screened using a multi-stage approach by two researchers to maintain consistency and limit bias.
    Results: Our initial search identified 2797 articles, of which 13 met our inclusion criteria (POTS n = 10; VVS n = 1; OH n = 1; VVS and POTS n = 1). Fatigue scores were significantly higher in patients with orthostatic syncope than healthy controls, and were particularly severe in those with POTS. Fatigue associated with orthostatic syncope disorders spanned multiple domains, with each dimension contributing equally to increased fatigue. "Brain fog" was an important symptom of POTS, negatively affecting productivity and cognition. Finally, fatigue was negatively associated with mental health in patients with POTS.
    Conclusion: In conditions of orthostatic syncope, fatigue is prevalent and debilitating, especially in patients with POTS. The consideration of fatigue in patients with orthostatic disorders is essential to improve diagnosis and management of symptoms, thus improving quality of life for affected individuals.
    MeSH term(s) Fatigue/epidemiology ; Fatigue/etiology ; Humans ; Hypotension, Orthostatic/complications ; Hypotension, Orthostatic/diagnosis ; Hypotension, Orthostatic/epidemiology ; Postural Orthostatic Tachycardia Syndrome/complications ; Postural Orthostatic Tachycardia Syndrome/diagnosis ; Postural Orthostatic Tachycardia Syndrome/epidemiology ; Quality of Life ; Syncope/diagnosis ; Syncope/epidemiology ; Syncope/etiology ; Syncope, Vasovagal/diagnosis ; Tilt-Table Test
    Language English
    Publishing date 2022-06-10
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1080007-4
    ISSN 1619-1560 ; 0959-9851
    ISSN (online) 1619-1560
    ISSN 0959-9851
    DOI 10.1007/s10286-022-00868-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Kategorien

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