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  1. Book ; Online ; E-Book: Materials for Medical Applications

    Khan, Firdos Alam

    Principles and Practices

    2024  

    Abstract: This book discusses advanced knowledge about the synthesis and application of materials in the medical field for diagnostic and therapeutic conditions. These materials have been extensively used in various biological and medical applications especially ... ...

    Author's details edited by Firdos Alam Khan
    Abstract This book discusses advanced knowledge about the synthesis and application of materials in the medical field for diagnostic and therapeutic conditions. These materials have been extensively used in various biological and medical applications especially in drug delivery, tumor screening, bioimaging, diagnosis, and also in therapies.
    Keywords Biomedical materials
    Subject code 610.28
    Language English
    Size 1 online resource (354 pages)
    Edition First edition.
    Publisher CRC Press
    Publishing place Boca Raton, FL
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-000-92470-X ; 9781032330075 ; 978-1-000-92470-1 ; 1032330074
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Stem cell production

    Khan, Firdos Alam

    processes, practices and regulations

    (Gale eBooks)

    2022  

    Abstract: This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various ... ...

    Author's details Firdos Alam Khan, editor
    Series title Gale eBooks
    Abstract This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases.
    Keywords Stem cells
    Subject code 616.02774
    Language English
    Dates of publication 2022-2022
    Size 1 online resource (xi, 272 pages) :, color illustrations
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-7588-0 ; 981-16-7589-9 ; 978-981-16-7588-1 ; 978-981-16-7589-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Advances in application of stem cells

    Khan, Firdos Alam

    from bench to clinics

    (Stem Cell Biology and Regenerative Medicine ; Volume 69)

    2021  

    Author's details edited by Firdos Alam Khan
    Series title Stem Cell Biology and Regenerative Medicine ; Volume 69
    Keywords Medicine ; Tissue engineering ; Stem cells
    Subject code 610
    Language English
    Size 1 online resource (320 pages)
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-78101-1 ; 3-030-78100-3 ; 978-3-030-78101-9 ; 978-3-030-78100-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book: Stem Cell Production

    Khan, Firdos Alam

    Processes, Practices and Regulations

    2022  

    Abstract: This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various ... ...

    Author's details Firdos Alam Khan is a Professor and Chairman at the Department of Stem Cell Biology, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia. He has obtained his Ph.D. in Zoology with a specialization in Neuroscience from Nagpur University, India. Over the past 24 years, Professor Khan is involved in teaching various courses such as Cell Biology, Pharmacology, Business of Biotechnology, Biomedicine, Cell & Tissue Engineering, and Bioethics & IPR to undergraduate and postgraduate students. He was previously associated with the Manipal Academy of Higher Education, Dubai Campus, United Arab Emirates. He was a Professor and Chairperson, School of Life Sciences and served as Chairman of Research & Development Program. He has published more than 75 research articles in several peer-reviewed journals
    Abstract This book examines the technologies and processes for the development and commercial production of stem cells according to cGMP guidelines. The initial chapter of the book discusses the therapeutic potentials of stem cells for the treatment of various diseases, including degenerative disorders and genetic diseases. The book then reviews the recent developments in the cultivation of stem cells in bioreactors, including critical cultural parameters, possible bioreactor configuration and integra...
    Keywords Stemcellproduction ; Stemcellsterility ; Stemcellclinicaltrials ; Stemcellbioreactor ; cGMPinspection ; Stem cell production ; Stem cell sterility ; Stem cell clinical trials ; Stem cell bioreactor ; cGMP inspection
    Language English
    Size 284 p.
    Edition 1
    Publisher Springer Nature Singapore
    Document type Book
    Note PDA Manuell_14
    Format 160 x 241 x 21
    ISBN 9789811675881 ; 9811675880
    Database PDA

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  5. Article ; Online: Synthesis, Characterization, and Biological Screening of Nanomaterials and Biomaterials.

    Khan, Firdos Alam

    Combinatorial chemistry & high throughput screening

    2021  Volume 24, Issue 10, Page(s) 1527

    MeSH term(s) Biocompatible Materials/chemical synthesis ; Biocompatible Materials/chemistry ; Nanostructures/chemistry
    Chemical Substances Biocompatible Materials
    Language English
    Publishing date 2021-09-16
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 2064785-2
    ISSN 1875-5402 ; 1386-2073
    ISSN (online) 1875-5402
    ISSN 1386-2073
    DOI 10.2174/138620732410210726091947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5577: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Electrospun Cu-Co ferrite nanofibers: synthesis, structure, optical and magnetic properties, and anti-cancer activity.

    Alahmari, Fatimah / Khan, Firdos Alam / Sozeri, H / Sertkol, M / Jaremko, Mariusz

    RSC advances

    2024  Volume 14, Issue 11, Page(s) 7540–7550

    Abstract: In this study, we investigated Cu-Co ferrite nanofibers (NFs) that were synthesized for the first time employing the electrospinning technique. The structure, phase purity and crystallite size of all the prepared NFs were revealed by powder X-ray ... ...

    Abstract In this study, we investigated Cu-Co ferrite nanofibers (NFs) that were synthesized for the first time employing the electrospinning technique. The structure, phase purity and crystallite size of all the prepared NFs were revealed by powder X-ray diffraction (PXRD) analysis. The NFs crystallized in the
    Language English
    Publishing date 2024-03-04
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra08087k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Progress and Perspectives in Colon Cancer Pathology, Diagnosis, and Treatments.

    Alrushaid, Noor / Khan, Firdos Alam / Al-Suhaimi, Ebtesam / Elaissari, Abdelhamid

    Diseases (Basel, Switzerland)

    2023  Volume 11, Issue 4

    Abstract: Worldwide, colon cancer is the third most frequent malignancy and the second most common cause of death. Although it can strike anybody at any age, colon cancer mostly affects the elderly. Small, non-cancerous cell clusters inside the colon, commonly ... ...

    Abstract Worldwide, colon cancer is the third most frequent malignancy and the second most common cause of death. Although it can strike anybody at any age, colon cancer mostly affects the elderly. Small, non-cancerous cell clusters inside the colon, commonly known as polyps, are typically where colon cancer growth starts. But over time, if left untreated, these benign polyps may develop into malignant tissues and develop into colon cancer. For the diagnosis of colon cancer, with routine inspection of the colon region for polyps, several techniques, including colonoscopy and cancer scanning, are used. In the case identifying the polyps in the colon area, efforts are being taken to surgically remove the polyps as quickly as possible before they become malignant. If the polyps become malignant, then colon cancer treatment strategies, such as surgery, chemotherapy, targeted therapy, and immunotherapy, are applied to the patients. Despite the recent improvements in diagnosis and prognosis, the treatment of colorectal cancer (CRC) remains a challenging task. The objective of this review was to discuss how CRC is initiated, and its various developmental stages, pathophysiology, and risk factors, and also to explore the current state of colorectal cancer diagnosis and treatment, as well as recent advancements in the field, such as new screening methods and targeted therapies. We examined the limitations of current methods and discussed the ongoing need for research and development in this area. While this topic may be serious and complex, we hope to engage and inform our audience on this important issue.
    Language English
    Publishing date 2023-10-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720869-2
    ISSN 2079-9721
    ISSN 2079-9721
    DOI 10.3390/diseases11040148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Nanotechnology in Cancer Diagnosis and Treatment.

    Alrushaid, Noor / Khan, Firdos Alam / Al-Suhaimi, Ebtesam Abdullah / Elaissari, Abdelhamid

    Pharmaceutics

    2023  Volume 15, Issue 3

    Abstract: Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs), which have made the process easier and faster. NPs possess exceptional properties such as a larger surface area, higher volume proportion, and better targeting ... ...

    Abstract Traditional cancer diagnosis has been aided by the application of nanoparticles (NPs), which have made the process easier and faster. NPs possess exceptional properties such as a larger surface area, higher volume proportion, and better targeting capabilities. Additionally, their low toxic effect on healthy cells enhances their bioavailability and
    Language English
    Publishing date 2023-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics15031025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Emerging trends in the application of gold nanoformulations in colon cancer diagnosis and treatment.

    Aldahhan, Razan / Almohazey, Dana / Khan, Firdos Alam

    Seminars in cancer biology

    2021  Volume 86, Issue Pt 2, Page(s) 1056–1065

    Abstract: Colorectal cancer is one of the most aggressive types of cancer with about two million new cases and one million deaths in 2020. The side effects of the available chemotherapies and the possibility of developing resistance against treatment highlight the ...

    Abstract Colorectal cancer is one of the most aggressive types of cancer with about two million new cases and one million deaths in 2020. The side effects of the available chemotherapies and the possibility of developing resistance against treatment highlight the importance of developing new therapeutic options. The development in the field of nanotechnology have introduced the application of nanoparticles (NPs) as a promising approach in the diagnosis and treatments of colorectal cancer and other types of cancer. Gold nanoparticles (AuNPs) are currently one of the most studied materials as they possess unique tunable properties allowing them to play a role in colorectal cancer bioimaging, diagnosis, and therapy. The high surface-to-volume ratio of AuNPs mediates their utilization in drug delivery as well as functionalization to provide specific targeting. Moreover, depending on their physical properties (size, shape), AuNPs can be modified to fit the intended application. However, there are contradictory results around the pharmacokinetics of AuNPs including their biodistribution, clearance, and toxicity. This variation of opinions is most likely due to the development of different AuNPs that vary in shape, size, and surface chemistry, in addition to the conditions under which each research was carried out. The conflicting data represent a challenge in the clinical use of AuNPs suggesting the need to understand the toxicity, fate, and long-term exposure of AuNPs in vivo. Thus, there is an unmet need for the establishment of a publicly available data base for extensive analysis. In this review, we discuss the recent advances in AuNP applications in the treatment and diagnosis of colorectal cancer, mechanisms of action, and clinical challenges.
    MeSH term(s) Humans ; Gold/chemistry ; Gold/pharmacokinetics ; Gold/toxicity ; Metal Nanoparticles/therapeutic use ; Metal Nanoparticles/chemistry ; Metal Nanoparticles/toxicity ; Tissue Distribution ; Drug Delivery Systems ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/drug therapy
    Chemical Substances Gold (7440-57-5)
    Language English
    Publishing date 2021-11-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1033980-2
    ISSN 1096-3650 ; 1044-579X
    ISSN (online) 1096-3650
    ISSN 1044-579X
    DOI 10.1016/j.semcancer.2021.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2922: Show issues Location:
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  10. Article ; Online: Impact of gold nanoparticles on colon cancer treatment and diagnosis.

    Khan, Firdos Alam / Aldahhan, Razan / Almohazey, Dana

    Nanomedicine (London, England)

    2021  Volume 16, Issue 10, Page(s) 779–782

    MeSH term(s) Colonic Neoplasms/diagnosis ; Colonic Neoplasms/drug therapy ; Gold ; Humans ; Metal Nanoparticles
    Chemical Substances Gold (7440-57-5)
    Language English
    Publishing date 2021-03-19
    Publishing country England
    Document type Editorial
    ZDB-ID 2277839-1
    ISSN 1748-6963 ; 1743-5889
    ISSN (online) 1748-6963
    ISSN 1743-5889
    DOI 10.2217/nnm-2021-0043
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6617: Show issues Location:
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