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  1. Article ; Online: A Case of Neuroretinitis following Inactivated Virion COVID-19 Vaccination.

    Nair, Gayathry S / Khan, Iraj Alam / Rizvi, Syed Wajahat Ali / Shahid, Saima

    Ocular immunology and inflammation

    2023  Volume 31, Issue 6, Page(s) 1279–1282

    Abstract: Purpose: We report a rare presentation of neuroretinitis following vaccination with inactivated virion vaccine (COVAXIN).: Methods: Interventional Case Report.: Observation: A 14-year-old female presented with sudden unilateral vision loss 3 days ... ...

    Abstract Purpose: We report a rare presentation of neuroretinitis following vaccination with inactivated virion vaccine (COVAXIN).
    Methods: Interventional Case Report.
    Observation: A 14-year-old female presented with sudden unilateral vision loss 3 days following COVID-19 vaccination. The clinical and radiological evaluation was consistent with classical neuroretinitis; the serological and immunological workup was negative. The patient responded well to the pulse steroid therapy and regained complete vision.
    Conclusion: The COVID-19 vaccine related adverse ocular events are beginning to emerge slowly and thus warrants close monitoring of all such cases. Also, ophthalmologists should be encouraged to seek vaccination status of patients presenting with inflammatory ocular conditions.
    MeSH term(s) Adolescent ; Female ; Humans ; Chorioretinitis/complications ; COVID-19/complications ; COVID-19 Vaccines/adverse effects ; Retinitis/drug therapy ; Vaccination/adverse effects
    Chemical Substances BBV152 COVID-19 vaccine (76JZE5DSN6) ; COVID-19 Vaccines
    Language English
    Publishing date 2023-02-13
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2023.2173244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Safety of Vasopressor Medications through Peripheral Line in Pediatric Patients in PICU in a Resource-Limited Setting.

    Abrar, Saira / Abbas, Qalab / Inam, Maha / Khan, Iraj / Khalid, Farah / Raza, Syed

    Critical care research and practice

    2022  Volume 2022, Page(s) 6160563

    Abstract: Objective: Central venous catheter (CVC) placement in children in resource-limited settings (RLSs) can be a difficult task. Timely administration of vasopressor medications (VMs) through peripheral intravenous line (PIV) can help overcome this ... ...

    Abstract Objective: Central venous catheter (CVC) placement in children in resource-limited settings (RLSs) can be a difficult task. Timely administration of vasopressor medications (VMs) through peripheral intravenous line (PIV) can help overcome this limitation. We aim to determine the safety of administration of vasopressor medications through PIVs in children admitted to pediatric intensive care unit (PICU) in a RLS.
    Design: Prospective observational study.
    Conclusion: Vasopressor medication through PIV line is a safe option in patients admitted to the PICU.
    Language English
    Publishing date 2022-03-31
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2573849-5
    ISSN 2090-1313 ; 2090-1305
    ISSN (online) 2090-1313
    ISSN 2090-1305
    DOI 10.1155/2022/6160563
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Multisystem Inflammatory Syndrome (MIS-C) As Cardiac Tamponade: Is It the Cause of Activation of Latent Tuberculosis?

    Nain, Zulquar / Abqari, Shaad / Afzal, Kamran / Khan, Iraj Alam / Izhar, Fazil M / Pk, Muhammed Saleeq

    Indian journal of pediatrics

    2022  Volume 89, Issue 4, Page(s) 419

    MeSH term(s) COVID-19 ; Cardiac Tamponade/diagnosis ; Cardiac Tamponade/etiology ; Humans ; Latent Tuberculosis ; SARS-CoV-2 ; Systemic Inflammatory Response Syndrome/diagnosis
    Language English
    Publishing date 2022-01-27
    Publishing country India
    Document type Letter
    ZDB-ID 218231-2
    ISSN 0973-7693 ; 0019-5456
    ISSN (online) 0973-7693
    ISSN 0019-5456
    DOI 10.1007/s12098-021-04026-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Role of Whole-Spine Screening Magnetic Resonance Imaging Using Short Tau Inversion Recovery or Fat-Suppressed T2 Fast Spin Echo Sequences for Detecting Noncontiguous Multiple-Level Spinal Tuberculosis.

    Siddiqui, Mohammed Azfar / Sartaj, Sara / Rizvi, Syed Wajahat A / Khan, Mohammad Jesan / Khan, Iraj Alam

    Asian spine journal

    2018  Volume 12, Issue 4, Page(s) 686–690

    Abstract: Study design: Retrospective review.: Purpose: The purpose of the present study was to evaluate the role of whole-spine screening using short tau inversion recovery (STIR) or fat-suppressed T2W fast spin echo (FSE) sequences in patients with spinal ... ...

    Abstract Study design: Retrospective review.
    Purpose: The purpose of the present study was to evaluate the role of whole-spine screening using short tau inversion recovery (STIR) or fat-suppressed T2W fast spin echo (FSE) sequences in patients with spinal tuberculosis (TB).
    Overview of literature: The identification of noncontiguous multiple-level spinal tuberculosis (NMLST), symptomatic or not, is important because of its management implications. Most centers do not perform routine whole-spine magnetic resonance imaging (MRI), and the reported incidence of NMLST varies from 1.1% to 74.1%.
    Methods: We completed a retrospective review of clinical and radiographic data of 365 patients with spinal TB who presented at Jawaharlal Nehru Medical College, Aligarh over 5 years. The final analysis included 187 patients who full filled the inclusion criteria, consisting of availability of whole-spine MRI and confirmation of vertebral TB. Diagnosis of NMLST was considered when other vertebral lesions were identified in addition to the primary vertebral disease, with the lesions separated by at least one normal spinal segment. The primary site was defined as the site for which the patient had been referred for MRI.
    Results: NMLST was identified in 47 of 187 patients investigated using whole-spine MRI. The incidence was 25.1%, which was higher than that in earlier reports where whole-spine MRI was not routinely performed. The lumbar spine was involved in 37 patients, thoracic spine in 25, cervical spine in 16, and sacrum in five patients. Combined lumbar spine and thoracic spine involvement was observed in 19 patients. Thirteen patients had lumbar and cervical spine involvement, nine had thoracic and cervical spine involvement, four had combined lumbar and sacral spine involvement, and the remaining two had thoracic and sacral spine involvement.
    Conclusions: Tubercular spondylitis may affect the spine at multiple noncontiguous sites with the majority of additional affected sites remaining asymptomatic. Routine whole-spine MRI using all recommended sequences is not cost-effective and hence not feasible. Therefore, we recommend whole-spine screening using STIR or fat-suppressed T2W FSE sequences in all patients with suspected spinal TB. This screening is cost-effective compared with full-protocol MRI and detects additional cases of NMLST over conventional practice.
    Language English
    Publishing date 2018-07-27
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2559763-2
    ISSN 1976-7846 ; 1976-1902
    ISSN (online) 1976-7846
    ISSN 1976-1902
    DOI 10.31616/asj.2018.12.4.686
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Newborn with meroanencephaly: Surviving all odds.

    Khan, Iraj Alam / Firdaus, Uzma / Ali, Syed Manazir / Asghar, Imran

    Journal of pediatric neurosciences

    2016  Volume 11, Issue 3, Page(s) 228–229

    Abstract: Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms - ... ...

    Abstract Neural tube defects are a group of congenital anomalies of brain development that carry a significant risk of morbidity and mortality. Anencephaly is a serious form of this defect with a very poor prognosis. It can present in three forms - meroanencephaly, holoanencephaly, and craniorachischisis. Meroanencephaly is considered to be the classic form of anencephaly. It manifests as a lack of cranial vault bones and exposed dorsal neural tissue resulting from defective neural tube closure in the very early period of gestation. Antenatally, the diagnosis may be suggested by ultrasound examination and by elevated maternal alpha-fetoprotein level. Here, we describe a case of meroanencephaly who was discharged from the hospital in fair condition despite the life-threatening anomaly.
    Language English
    Publishing date 2016-09-26
    Publishing country India
    Document type Case Reports
    ISSN 1817-1745
    ISSN 1817-1745
    DOI 10.4103/1817-1745.193360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Ovarian Torsion as an Unusual Presentation of Primary Bilateral Ovarian Lymphoma

    Siddiqui, Mohammed Azfar / Sartaj, Sara / Ali Rizvi, Syed Wajahat / Khan, Iraj Alam

    Indian Journal of Medical and Paediatric Oncology

    2018  Volume 39, Issue 01, Page(s) 88–90

    Abstract: Primary ovarian involvement by Burkitt's lymphoma is rare and accounts for 0.5% of nonHodgkin lymphoma and 1.5% of ovarian tumors. We herein describe a very rare case of primary bilateral ovarian lymphoma in a 14-year-old presenting as ovarian torsion. ...

    Abstract Primary ovarian involvement by Burkitt's lymphoma is rare and accounts for 0.5% of nonHodgkin lymphoma and 1.5% of ovarian tumors. We herein describe a very rare case of primary bilateral ovarian lymphoma in a 14-year-old presenting as ovarian torsion.
    Keywords Burkitt ; non-Hodgkin lymphoma ; ovarian lymphoma ; torsion
    Language English
    Publishing date 2018-01-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2181724-8
    ISSN 0975-2129 ; 0971-5851 ; 0975-2129
    ISSN (online) 0975-2129
    ISSN 0971-5851 ; 0975-2129
    DOI 10.4103/ijmpo.ijmpo_68_17
    Database Thieme publisher's database

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  7. Article: The quality of patient care in oncology departments in Karachi, Pakistan: patients' perceptions.

    Fayyaz, Risha / Ahmed, Fasih Ali / Abid, Adeel / Akhtar, Afshan / Jarwar, Rabail / Jasmine, Anila / Khan, Sameer Ahmad / Shahid, Shahira / Khan, Iraj / Yousuf, Aneeq Muhammad / Jehan, Imtiaz

    International journal of health care quality assurance

    2020  Volume ahead-of-print, Issue ahead-of-print

    Abstract: Purpose: This study aims to assess the quality of care among adult oncology patients in tertiary care hospitals in Karachi by using an international standard of quality of care and to identify domains where improvement is needed.: Design/methodology/ ... ...

    Abstract Purpose: This study aims to assess the quality of care among adult oncology patients in tertiary care hospitals in Karachi by using an international standard of quality of care and to identify domains where improvement is needed.
    Design/methodology/approach: This is a cross-sectional study carried out at two tertiary care hospitals of Karachi, Pakistan, belonging to private and public sector, respectively, between February and April 2018. Face-to-face interviews were conducted using a modified questionnaire having five-point Likert scale questions regarding satisfaction of patients with doctors, nursing staff, information provided and the hospital standards. SPSS 20 was used for statistical analysis, and the results were expressed using mean, frequencies, percentages and
    Findings: The authors approached 415 patients, out of which 389 patients agreed to participate in the study. For both hospitals, the lowest mean scores were for sections pertaining to satisfaction with psychosocial support and information provided. The mean satisfaction score of patients from the private hospital were found to be significantly higher as compared to patients from the public hospital for all domains of patient care (
    Research limitations/implications: A comparative study should be conducted with the aim of pinpointing the differences in areas in which there is a significant difference in positive satisfaction levels between private and public sectors. Similar research could also be expanded adding other variables that affect quality of care such as doctor's approach to their patients, time given during each consultation and patient's understanding of doctor's knowledge. Further studies can be done to bridge the gaps between what a doctor views as standard care and what the patient knows will help them receive a more holistic approach to care.
    Practical implications: Assessing the quality of care helps determine gaps in care and allocating health resources accordingly. In clinical practice, emphasis needs to be given on increased duration and improved quality of patient counselling to improve the low satisfaction levels of patients regarding the psychosocial support. Addressing patients' concerns should be made part of clinical teaching from an undergraduate level. As far as patient access to doctors of the specific speciality is concerned, hospital managements should adopt systems to ensure continuum of care and come up with mechanisms to bridge the discrepancy between a patient's needs and doctor availability.
    Social implications: After being identified as a major deficiency, training doctors in the sensitivities of the population and demographics, especially with respect to socio-economic statuses, can aid in enhancing patient satisfaction to the treatment. Implementation of patient-centred care leads to greater satisfaction with care, which, in turn, increases a patient's self efficacy in managing important aspects of their care and improves health care-related quality of life.
    Originality/value: Cancer patients have long-term exposure to the hospital environment. A patient's satisfaction with the quality of care is an important determinant in patient compliance to the treatment protocol and required hospital visits. There is a dearth of research on the outpatient quality of care in the oncology departments in Karachi. This study provides an overview of the quality of care available to cancer patients in Karachi both in public and private sectors. The results of our study identify the gaps in the quality of care being provided to the patients in a developing country like Pakistan, which can be used to improve the quality of care, leading to better patient outcomes.
    Language English
    Publishing date 2020-12-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 645125-1
    ISSN 0952-6862 ; 1366-0756
    ISSN 0952-6862 ; 1366-0756
    DOI 10.1108/IJHCQA-12-2019-0201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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