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  1. Article ; Online: Nonconvulsive Status Epilepticus - A Rare Presentation of Cortical-brainstem Encephalitis Phenotype of SARS-COV-2-triggered MOGAD.

    Patel, Pratik / Arora, Anka / Tiwari, Sarbesh / Khan, Md Atik / Panda, Samhita

    Neurology India

    2023  Volume 71, Issue 3, Page(s) 594–595

    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19/complications ; Status Epilepticus/etiology ; Electroencephalography ; Encephalitis/complications ; Brain Stem
    Language English
    Publishing date 2023-06-16
    Publishing country India
    Document type Case Reports ; Letter
    ZDB-ID 415522-1
    ISSN 1998-4022 ; 0028-3886
    ISSN (online) 1998-4022
    ISSN 0028-3886
    DOI 10.4103/0028-3886.378689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 698: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Redefining the role of therapeutic plasma exchange in complications of

    Bava, Davood / Kumar, P H Akhilesh / Gupta, Anubhav / Mandal, Saptarshi / Bajpayee, Archana / Gopalakrishnan, Maya / Khan, Md Atik

    Asian journal of transfusion science

    2022  Volume 17, Issue 2, Page(s) 295–300

    Abstract: Introduction: Saw-scaled viper (: Aim and objectives: To report the safety and efficacy of therapeutic plasma exchange procedures in the setting of ASV refractory : Materials and methods: Four patients admitted to our institute in 2021 September ... ...

    Abstract Introduction: Saw-scaled viper (
    Aim and objectives: To report the safety and efficacy of therapeutic plasma exchange procedures in the setting of ASV refractory
    Materials and methods: Four patients admitted to our institute in 2021 September with an alleged history of snake bites and who underwent at least one cycle of therapeutic plasma exchange were assessed for clinical outcome, laboratory parameters, and blood product consumption.
    Results: Three adult patients and one pediatric patient are included in this case series, all of them males. Indication for TPE in one case was suspected diffuse alveolar hemorrhage (DAH), while in all the other cases was thrombotic microangiopathy (TMA). All received a variable number of sessions from 2 to 5 and 1.3-1.5 plasma volume was removed on an average per cycle. The endpoint of TPE was the resolution of DAH in one while a reduction in lactate dehydrogenase and an increase in platelet count was in TMA cases. Consumption of blood products was drastically reduced in all four patients after starting the procedure. All the adult patients fared well on follow-up while the child had developed acute cortical necrosis and was dialysis-dependent. It has been noted in the previous studies too that a subset of snakebite-induced TMA cases was getting converted to chronic kidney disease and becoming dialysis dependent in the long run.
    Conclusions: In regions where ASV treatment failure is very common, therapeutic plasma exchange is a safe and effective complementary treatment modality along with supportive care.
    Language English
    Publishing date 2022-12-12
    Publishing country India
    Document type Case Reports
    ZDB-ID 2267310-6
    ISSN 1998-3565 ; 0973-6247
    ISSN (online) 1998-3565
    ISSN 0973-6247
    DOI 10.4103/ajts.ajts_49_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparing novel versus conventional technique of platelet-rich plasma therapy in periorbital hyperpigmentation: A randomized prospective split-face study.

    Budania, Anil / Mandal, Saptarshi / Pathania, Yashdeep Singh / Lahoria, Utkrist / Khan, Md Atik / Puri, Inder / Mishra, Richa

    Journal of cosmetic dermatology

    2021  Volume 20, Issue 10, Page(s) 3245–3252

    Abstract: Background: Platelet-rich plasma (PRP) has been found to be effective in treating periorbital hyperpigmentation (POH). PRP prepared by double-spin (DS) method and activated by calcium has been used conventionally. PRP can be prepared by single spin (SS) ...

    Abstract Background: Platelet-rich plasma (PRP) has been found to be effective in treating periorbital hyperpigmentation (POH). PRP prepared by double-spin (DS) method and activated by calcium has been used conventionally. PRP can be prepared by single spin (SS) and activated at low temperature (novel method), but the evidence is limited.
    Objective: To compare the novel and conventional PRP in the treatment of periorbital hyperpigmentation.
    Methods: We selected 21 patients of POH and randomly divided the face into two halves. One-half of the face (group A) was treated with novel PRP (SS and low-temperature activation). The other half (group B) was treated with conventional PRP (DS and calcium activation). A total of 3 PRP injections were given at 4 weekly intervals. Patients were observed and assessed on 12
    Results: Mean platelet count in novel and conventional PRP was 7.41 ± 1.76 lacs and 8.17 ± 2.23 lacs (p = 0.348). Mean photographic and dermoscopic assessment at the end of the study in group A and group B was 52.33 ± 6.468 and 53.14 ± 6.99 (p = 0.151). Change in VAS in groups A and B was 3.85 ± 1.27 and 3.90 ± 1.04 (p = 0.895). Levels of various growth factors assessed by ELISA did not differ significantly. There was significant decline in DLQI.
    Conclusion: The novel method is not inferior to conventional method of PRP in the treatment of periorbital hyperpigmentation.
    MeSH term(s) Humans ; Hyperpigmentation/therapy ; Intercellular Signaling Peptides and Proteins ; Platelet-Rich Plasma ; Prospective Studies ; Treatment Outcome
    Chemical Substances Intercellular Signaling Peptides and Proteins
    Language English
    Publishing date 2021-04-28
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.14121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6539: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Clinical Post-operative Bleeding During Minor Oral Surgical Procedure and In Vitro Platelet Aggregation in Patients on Aspirin Therapy: Are they Coherent?

    Singh, Surjit / Mandal, Saptarshi / Chugh, Ankita / Deora, Surender / Jain, Gaurav / Khan, Md Atik / Chugh, Vinay Kumar

    Journal of maxillofacial and oral surgery

    2020  Volume 20, Issue 1, Page(s) 132–137

    Abstract: Aim: The risk of excessive bleeding prompts physicians to discontinue aspirin in patients on low-dose, long-term therapy which in turn puts them at the risk from adverse cardiovascular and thrombotic events. Effect of low-dose aspirin therapy on ... ...

    Abstract Aim: The risk of excessive bleeding prompts physicians to discontinue aspirin in patients on low-dose, long-term therapy which in turn puts them at the risk from adverse cardiovascular and thrombotic events. Effect of low-dose aspirin therapy on platelet function was assessed using platelet aggregation method. The aim was to correlate the laboratory platelet function with cutaneous and clinical oral bleeding time (BT).
    Materials and methods: One hundred one patients were enrolled in this prospective trial and were allocated into two groups. Interventional or test group consisted of patients who were on aspirin therapy (75 mg/100 mg) for primary or secondary prevention of angina, myocardial infarction and stroke. Minor oral surgical procedure was performed in this group without discontinuing aspirin therapy. Control group consisted of healthy patients (under no medication) undergoing minor oral surgical procedure. Cutaneous and clinical oral BT were recorded in both the groups. Venous blood sample was drawn, and percentage platelet aggregation function was analysed using adenosine diphosphate (ADP) and arachidonic acid (AA) reagents. The percentage of platelet aggregation was then correlated with cutaneous and clinical oral BT.
    Results: A significant decrease in percentage platelet aggregation using ADP (aspirin-74.7 21.39; control-89.2 13.70) and AA (aspirin-47.6 23.11; control-82.3 20.17) was observed. However, there were no significant difference in mean cutaneous BT (aspirin-1.5 0.65 min; control-1.6 0.71 min) and clinical oral BT (aspirin-5.0 2.48 min; control-4.8 2.60 min) in aspirin and control groups.
    Conclusion: Majority of the minor oral surgical procedures can be carried out safely without discontinuing aspirin in patients on low-dose long-term therapy. This is possible because despite significant platelet aggregation evident in laboratory evaluation there is lack of its clinical corroboration owing to aspirin resistance.
    Clinical trial registration: CTRI/2018/02/012055.
    Language English
    Publishing date 2020-08-20
    Publishing country India
    Document type Journal Article
    ZDB-ID 2502352-4
    ISSN 0974-942X ; 0972-8279
    ISSN (online) 0974-942X
    ISSN 0972-8279
    DOI 10.1007/s12663-020-01438-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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