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  1. Article ; Online: Funding Life-Extension Research.

    Khan, Mehmood

    Cold Spring Harbor perspectives in medicine

    2023  

    Abstract: While the worldwide trend in life expectancy continues to increase slightly overall, the trend for the last few decades in developed countries is that more people are spending more years in poor health with multiple chronic comorbidities. These chronic ... ...

    Abstract While the worldwide trend in life expectancy continues to increase slightly overall, the trend for the last few decades in developed countries is that more people are spending more years in poor health with multiple chronic comorbidities. These chronic conditions in aging populations consume high proportions of national healthcare budgets. The relatively young field of longevity research, after accumulating insights into the mechanisms of aging and producing dramatic laboratory demonstrations of life extension in some organisms, is entering the translational phase. This phase, through clinical trials, will confirm or refute the "geroscience hypothesis" that drugs can change the trajectory of the processes of aging within cells, and ultimately in living humans. At the same time, traditional funding patterns do not favor such visionary "moonshot" research, which, despite the potential for ultimately providing benefits for everyone, offers little prospect for rapid return on investment and high probabilities for early phase failure. New radical funding strategies incentivizing innovation will have to be called into play.
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ISSN 2157-1422
    ISSN (online) 2157-1422
    DOI 10.1101/cshperspect.a041208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Short-term wind power forecasting through stacked and bi directional LSTM techniques.

    Ali Khan, Mehmood / Khan, Iftikhar Ahmed / Shah, Sajid / El-Affendi, Mohammed / Jadoon, Waqas

    PeerJ. Computer science

    2024  Volume 10, Page(s) e1949

    Abstract: Background: Computational intelligence (CI) based prediction models increase the efficient and effective utilization of resources for wind prediction. However, the traditional recurrent neural networks (RNN) are difficult to train on data having long- ... ...

    Abstract Background: Computational intelligence (CI) based prediction models increase the efficient and effective utilization of resources for wind prediction. However, the traditional recurrent neural networks (RNN) are difficult to train on data having long-term temporal dependencies, thus susceptible to an inherent problem of vanishing gradient. This work proposed a method based on an advanced version of RNN known as long short-term memory (LSTM) architecture, which updates recurrent weights to overcome the vanishing gradient problem. This, in turn, improves training performance.
    Methods: The RNN model is developed based on stack LSTM and bidirectional LSTM. The parameters like mean absolute error (MAE), standard deviation error (SDE), and root mean squared error (RMSE) are utilized as performance measures for comparison with recent state-of-the-art techniques.
    Results: Results showed that the proposed technique outperformed the existing techniques in terms of RMSE and MAE against all the used wind farm datasets. Whereas, a reduction in SDE is observed for larger wind farm datasets. The proposed RNN approach performed better than the existing models despite fewer parameters. In addition, the approach requires minimum processing power to achieve compatible results.
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.1949
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Global Healthspan Summit 2023: closing the gap between healthspan and lifespan.

    Khan, Mehmood / Al Saud, Haya / Sierra, Felipe / Perez, Viviana / Greene, William / Al Asiry, Salman / Pathai, Sophia / Torres, Michael

    Nature aging

    2024  Volume 4, Issue 4, Page(s) 445–448

    MeSH term(s) Animals ; Longevity ; Aging ; Caenorhabditis elegans
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article
    ISSN 2662-8465
    ISSN (online) 2662-8465
    DOI 10.1038/s43587-024-00593-4
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  4. Article: Public-sector green procurement in the United Arab Emirates: Innovation capability and commitment to change

    AlNuaimi, Bader K / Khan, Mehmood

    Journal of cleaner production. 2019 Oct. 01, v. 233

    2019  

    Abstract: This paper examines various internal factors that influence green-procurement implementation in the public sector of the United Arab Emirates (UAE) by investigating the relationships between the innovation capability of organizations and green- ... ...

    Abstract This paper examines various internal factors that influence green-procurement implementation in the public sector of the United Arab Emirates (UAE) by investigating the relationships between the innovation capability of organizations and green-procurement implementation with the mediating impact of employees’ commitment to change.A structural model is proposed using scales from literature. Primary research data was collected using a cross-sectional survey involving 50 respondents from public-sector organizations in Abu Dhabi. Results revealed that the innovation capability of the organization has a positive influence on green-procurement implementation. In addition, employees’ commitment to change influences green-procurement implementation.This paper contributes to the literature by studying green-procurement implementation in the UAE's public sector, in which new constructs to existing concepts are introduced and tested. This paper also complements contemporary knowledge on green procurement, organizational innovation, and environmental practices. The paper emphasizes that top management and government officials must reevaluate their own personal values and commitment to certain issues as they formulate green-procurement policies, regulations, and training programs designed for procurement officials within the UAE's government organizations.This paper is expected to have multiple theoretical and practical implications to the study of green procurement in the UAE public sector and beyond and could set the stage to conduct more studies this field in the UAE in order to support the changes to come.
    Keywords cross-sectional studies ; education programs ; environmentally preferable purchasing ; human resources ; issues and policy ; models ; public sector ; United Arab Emirates
    Language English
    Dates of publication 2019-1001
    Size p. 482-489.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2019.06.090
    Database NAL-Catalogue (AGRICOLA)

    Full text online

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  5. Book ; Online: Green supply chain management for sustainable business practice

    Ajmal, Mian M / Hussain, Matloub / Khan, Mehmood

    (Advances in logistics, operations, and management science (ALOMS) book series ; Premier reference source)

    2017  

    Abstract: This book examines the challenges and benefits of implementing sustainability into the core functions of contemporary enterprises, focusing on how green approaches improve operations in an ecological way by highlighting key concepts, emerging ... ...

    Author's details Mehmood Khan (Abu Dhabi University, UAE), Matloub Hussain (Abu Dhabi University, UAE), Mian M. Ajmal (Abu Dhabi University, UAE)
    Series title Advances in logistics, operations, and management science (ALOMS) book series
    Premier reference source
    Abstract "This book examines the challenges and benefits of implementing sustainability into the core functions of contemporary enterprises, focusing on how green approaches improve operations in an ecological way by highlighting key concepts, emerging innovations, and future directions"--Provided by publisher

    Sustainable supply chains / Amulya Gurtu, Cory Searcy, Mohamad Y. Jaber -- An introduction to sustainable supply chain management and business implications / Gowri Vijayan, Nitty Hirawaty Kamarulzaman -- The development and analysis of environmentally responsible supply chain models / Ehab Bazan, Mohamad Y. Jaber -- Assessing the green supply chain management for the United Arab Emirates construction industry / Sreejith Balasubramanian, Balan Sundarakani -- A waste elimination process: an approach for lean and sustainable manufacturing systems / Sherif Mostafa, Jantanee Dumrak -- Green supply chain management model for sustainable manufacturing practices / Surajit Bag, Neeraj Anand, Krishan Kumar Pandey -- Recent developments in green supply chain management: sourcing and logistics / Jay R. Brown [and 3 others] -- Integrated sustainable supply chain management: current practices and future direction / Geevaneswary Saththasivam, Yudi Fernando -- Advocating sustainable supply chain management and sustainability in global supply chain / Kijpokin Kasemsap
    Keywords Business logistics/Environmental aspects ; Industrial ecology ; Materials management/Environmental aspects ; Nachhaltigkeit ; Supply Chain Management
    Language English
    Size 1 Online-Ressource (xvii, 330 Seiten), Illustrationen
    Publisher Business Science Reference
    Publishing place Hershey, PA, USA
    Document type Book ; Online
    Note Includes bibliographical references and index ; Restricted to subscribers or individual electronic text purchasers
    ISBN 9781522506355 ; 9781522506362 ; 1522506357 ; 1522506365
    Database ECONomics Information System

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  6. Book: Green supply chain management for sustainable business practice

    Ajmal, Mian M / Hussain, Matloub / Khan, Mehmood

    (Advances in logistics, operations, and management science (ALOMS) book series ; Premier reference source)

    2017  

    Abstract: This book examines the challenges and benefits of implementing sustainability into the core functions of contemporary enterprises, focusing on how green approaches improve operations in an ecological way by highlighting key concepts, emerging innovations, ...

    Author's details Mehmood Khan (Abu Dhabi University, UAE), Matloub Hussain (Abu Dhabi University, UAE), Mian M. Ajmal (Abu Dhabi University, UAE)
    Series title Advances in logistics, operations, and management science (ALOMS) book series
    Premier reference source
    Abstract This book examines the challenges and benefits of implementing sustainability into the core functions of contemporary enterprises, focusing on how green approaches improve operations in an ecological way by highlighting key concepts, emerging innovations, and future directions.
    Keywords Business logistics/Environmental aspects ; Industrial ecology ; Materials management/Environmental aspects ; Lieferkette ; Nachhaltigkeit
    Language English
    Size xvii, 330 Seiten, Illustrationen
    Document type Book
    Note Enthält 9 Beiträge ; Literaturangaben
    ISBN 9781522506355 ; 9781522506362 ; 1522506357 ; 1522506365
    Database ECONomics Information System

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  7. Article ; Online: Neural network-based adaptive global sliding mode MPPT controller design for stand-alone photovoltaic systems.

    Haq, Izhar Ul / Khan, Qudrat / Ullah, Safeer / Khan, Shahid Ahmed / Akmeliawati, Rini / Khan, Mehmood Ashraf / Iqbal, Jamshed

    PloS one

    2022  Volume 17, Issue 1, Page(s) e0260480

    Abstract: The increasing energy demand and the target to reduce environmental pollution make it essential to use efficient and environment-friendly renewable energy systems. One of these systems is the Photovoltaic (PV) system which generates energy subject to ... ...

    Abstract The increasing energy demand and the target to reduce environmental pollution make it essential to use efficient and environment-friendly renewable energy systems. One of these systems is the Photovoltaic (PV) system which generates energy subject to variation in environmental conditions such as temperature and solar radiations. In the presence of these variations, it is necessary to extract the maximum power via the maximum power point tracking (MPPT) controller. This paper presents a nonlinear generalized global sliding mode controller (GGSMC) to harvest maximum power from a PV array using a DC-DC buck-boost converter. A feed-forward neural network (FFNN) is used to provide a reference voltage. A GGSMC is designed to track the FFNN generated reference subject to varying temperature and sunlight. The proposed control strategy, along with a modified sliding mode control, eliminates the reaching phase so that the sliding mode exists throughout the time. The system response observes no chattering and harmonic distortions. Finally, the simulation results using MATLAB/Simulink environment demonstrate the effectiveness, accuracy, and rapid tracking of the proposed control strategy. The results are compared with standard results of the nonlinear backstepping controller under abrupt changes in environmental conditions for further validation.
    MeSH term(s) Neural Networks, Computer
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0260480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A note on

    Khan, Mehmood / Ahmad, Syed Zamberi / Jabeen, Fauzia

    International journal of integrated supply management : IJISM Vol. 10, No. 1 , p. 89-99

    an economic order quantity model for items with imperfect quality and inspection errors

    2016  Volume 10, Issue 1, Page(s) 89–99

    Author's details Mehmood Khan, Fauzia Jabeen and Syed Zamberi Ahmad
    Keywords batch sizing ; lot sizing ; EOQ/EPQ ; imperfect quality ; holding costs ; learning
    Language English
    Publisher Inderscience Enterprises
    Publishing place Olney, Bucks
    Document type Article
    ZDB-ID 2164920-0
    Database ECONomics Information System

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  9. Article: Analysis of capacity constraints on the backlog bullwhip effect in the two-tier supply chain

    Hussain, Matloub / Khan, Mehmood / Sabir, Hussein

    International journal of logistics : research and applications Vol. 19, No. 1 , p. 41-61

    a Taguchi approach

    2016  Volume 19, Issue 1, Page(s) 41–61

    Author's details Matloub Hussain, Mehmood Khan and Hussein Sabir (College of Business Administration, COBA, Abu Dhabi University, Abu Dhabi, UAE)
    Keywords supply chain dynamics ; Taguchi methods ; capacity constraints ; simulation ; APIOBPCS
    Language English
    Publisher Taylor & Francis
    Publishing place Abingdon
    Document type Article
    ZDB-ID 1401605-9 ; 2020197-7
    ISSN 1469-848X ; 1367-5567
    ISSN (online) 1469-848X
    ISSN 1367-5567
    Database ECONomics Information System

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  10. Article: A review of inventory lot sizing review papers

    Bushuev, Maxim / Guiffrida, Alfred / Jaber, M. Y / Khan, Mehmood

    Management research review Vol. 38, No. 3 , p. 283-298

    2015  Volume 38, Issue 3, Page(s) 283–298

    Author's details Maxim Bushuev and Alfred Guiffrida; M. Y. Jaber; Mehmood Khan
    Keywords Inventory lot sizing ; Inventory review ; Mathematical inventory models
    Language English
    Publisher Emerald
    Publishing place Bingley
    Document type Article
    ZDB-ID 2535152-7 ; 2538372-3
    ISSN 2040-8269 ; 2040-8277
    ISSN (online) 2040-8269
    ISSN 2040-8277
    Database ECONomics Information System

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