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Article: Marijuana as a Cause of Diffuse Coronary Vasospasm Leading to Cardiac Arrest.

Khan, Muhammad Atif / Khan, Faiza Humayun / Khan, Hina Benish / Brabham, David

2023 Volume 15, Issue 4, Page(s) e38026

Abstract: Marijuana is considered as the most popular illicit drug around the world. It has numerous cardiovascular effects with myocardial infarction (MI) being a lethal one. The negative physiological effects of marijuana are well-studied, including tachycardia, ...

Abstract	Marijuana is considered as the most popular illicit drug around the world. It has numerous cardiovascular effects with myocardial infarction (MI) being a lethal one. The negative physiological effects of marijuana are well-studied, including tachycardia, nausea, memory impairment, anxiety, panic, and arrhythmia. We present a case of cardiac arrest following marijuana use in a patient who had a normal electrocardiogram (EKG) on presentation but diffuse coronary vasospasm on left heart catheterization (LHC) with no obstructive lesion. The patient had a transient episode of ST elevation on EKG following the procedure which resolved with an increased dose of nitroglycerine drip. Synthetic cannabinoids are more potent and not detected on a regular urine drug screen (UDS). In patients with low risk for cardiovascular events, particularly young adults, presenting with symptoms of MI/cardiac arrest, marijuana-induced MI should be suspected due to the severe adverse effects of its synthetic component.
Language	English
Publishing date	2023-04-23
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.38026
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Article ; Online: Gastrointestinal bleeding in recipients of left ventricular assist devices-a systematic review.

Naveed, Ali / Naveed, Bazigh / Khan, Muhammad Atif / Asif, Talal

Heart failure reviews

2023 Volume 28, Issue 5, Page(s) 1163–1175

Abstract: The twenty-first century has revolutionized the management of congestive heart failure with the widespread use of left ventricular assist devices and other treatment modalities that improve morbidity and mortality after the failure of medical management. ...

Abstract	The twenty-first century has revolutionized the management of congestive heart failure with the widespread use of left ventricular assist devices and other treatment modalities that improve morbidity and mortality after the failure of medical management. These novel devices come with significant side effects. One of the most common side effects of left ventricular assist devices is the increased frequency of lower gastrointestinal bleeding compared to heart failure patients without left ventricular assist devices. Multiple etiologies of recurrent gastrointestinal bleeding in such patients have been studied. The decreased amount of von Willebrand factor polymers is now recognized as one of the most common causes of increased incidence of gastrointestinal bleeding in patients with left ventricular assist devices alongside increased arteriovenous malformations. Multiple treatment modalities have been identified to prevent and treat gastrointestinal bleeding in these patients. Since the use of left ventricular assist devices is becoming more prevalent in patients with advanced heart failure, we decided to conduct this systematic review. The article summarizes the incidence, pathophysiology, and management of lower gastrointestinal bleeding in patients with left ventricular assist devices.
MeSH term(s)	Humans ; Heart-Assist Devices/adverse effects ; Gastrointestinal Hemorrhage/epidemiology ; Gastrointestinal Hemorrhage/etiology ; Gastrointestinal Hemorrhage/therapy ; Heart Failure/complications ; Heart Failure/therapy ; Incidence
Language	English
Publishing date	2023-05-05
Publishing country	United States
Document type	Systematic Review ; Journal Article
ZDB-ID	1336499-6
ISSN	1573-7322 ; 1382-4147
ISSN (online)	1573-7322
ISSN	1382-4147
DOI	10.1007/s10741-023-10313-6
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Article: Emerging Two-Dimensional Materials-Based Electrochemical Sensors for Human Health and Environment Applications.

Khan, Muhammad Atif / Ramzan, Faizan / Ali, Muhammad / Zubair, Muhammad / Mehmood, Muhammad Qasim / Massoud, Yehia

Nanomaterials (Basel, Switzerland)

2023 Volume 13, Issue 4

Abstract: Two-dimensional materials (2DMs) have been vastly studied for various electrochemical sensors. Among these, the sensors that are directly related to human life and health are extremely important. Owing to their exclusive properties, 2DMs are vastly ... ...

Abstract	Two-dimensional materials (2DMs) have been vastly studied for various electrochemical sensors. Among these, the sensors that are directly related to human life and health are extremely important. Owing to their exclusive properties, 2DMs are vastly studied for electrochemical sensing. Here we have provided a selective overview of 2DMs-based electrochemical sensors that directly affect human life and health. We have explored graphene and its derivatives, transition metal dichalcogenide and MXenes-based electrochemical sensors for applications such as glucose detection in human blood, detection of nitrates and nitrites, and sensing of pesticides. We believe that the areas discussed here are extremely important and we have summarized the prominent reports on these significant areas together. We believe that our work will be able to provide guidelines for the evolution of electrochemical sensors in the future.
Language	English
Publishing date	2023-02-20
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662255-5
ISSN	2079-4991
ISSN	2079-4991
DOI	10.3390/nano13040780
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Article: Paper-based facile capacitive touch arrays for wireless mouse cursor control pad.

Arif, Myda / Zulfiqar, Muhammad Hamza / Khan, Muhammad Atif / Zubair, Muhammad / Mehmood, Muhammad Qasim / Massoud, Yehia

Heliyon

2023 Volume 9, Issue 9, Page(s) e19447

Abstract: Wireless devices have become extremely inexpensive and popular in recent years. The two most significant advantages of wireless devices over wired ones are convenience and flexibility. Considering this, a wireless mouse pad prototype for access has been ... ...

Abstract	Wireless devices have become extremely inexpensive and popular in recent years. The two most significant advantages of wireless devices over wired ones are convenience and flexibility. Considering this, a wireless mouse pad prototype for access has been developed in this study. A capacitive sensors-based mouse pad with basic operations and conventional features has been developed using sensing arrays on paper. A facile, do-it-yourself fabrication process was utilized to develop a cost-effective, thin, wearable, and cleanroom-free wireless mouse cursor control (MCC) pad. The ablation process was used to cut the traces of conductive tape and paste them onto the paper to develop the MCC pad. The pad was connected with Espressif Systems (ESP)32 to wirelessly control the cursor of mobile and laptop. The capacitive touch sensor array-based pad is easy to reproduce and recycle. This pad can contribute to future advancements in thin human-machine interfaces, soft robotics, and medical and healthcare applications.
Language	English
Publishing date	2023-08-26
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e19447
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Article: Invisible touch sensors-based smart and disposable door locking system for security applications.

Mehmood, Muhammad Qasim / Malik, Muhammad Shumail / Zulfiqar, Muhammad Hamza / Khan, Muhammad Atif / Zubair, Muhammad / Massoud, Yehia

Heliyon

2023 Volume 9, Issue 2, Page(s) e13586

Abstract: Nowadays, security is one of the living essentials, and there is a dire need for reliable, secure, and smarter locking systems. The stand-alone smart security systems are of great interest as they do not involve keys, cards, or unsecured communication in ...

Abstract	Nowadays, security is one of the living essentials, and there is a dire need for reliable, secure, and smarter locking systems. The stand-alone smart security systems are of great interest as they do not involve keys, cards, or unsecured communication in order to prevent carrying, loss, duplication, and hacking. Here, we report an invisible touch sensors-based smart door locking system (DLS). The passive transducer-based touch sensors are fabricated through a facile do-it-yourself (DIY) based fabrication process by pasting the hybrid geometry copper electrodes on cellulose paper. The employment of biodegradable, and non-toxic materials like paper and copper tape makes this configuration a good candidate for green electronics. For additional security, the keypad in the DLS is made invisible by covering it with paper and spray paint. One can only open the door by knowing the password as well as the location of each key on the sensor keypad. The system can efficiently recognize the exact pattern of passwords without any false values. Invisible touch sensors-based locking systems can easily contribute to the security applications in homes, banks, automobiles, apartments, lockers, and cabinets.
Language	English
Publishing date	2023-02-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e13586
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Article ; Online: Fast Response Facile Fabricated IDE-Based Ultra-sensitive Humidity Sensor for Medical Applications.

Ullah, Asad / Zulfiqar, Muhammad Hamza / Khan, Muhammad Atif / Zubair, Muhammad / Mehmood, Muhammad Qasim / Massoud, Yehia

ACS omega

2023 Volume 8, Issue 19, Page(s) 16842–16850

Abstract: An eco-friendly, biodegradable, flexible, and facile fabricated interdigital electrode-based capacitive humidity sensor with applications in health and medicine has been reported here. Several sensors use copper tape as electrodes on the polyethylene ... ...

Abstract	An eco-friendly, biodegradable, flexible, and facile fabricated interdigital electrode-based capacitive humidity sensor with applications in health and medicine has been reported here. Several sensors use copper tape as electrodes on the polyethylene terephthalate (PET) substrate, with non-woven paper as the sensing layer. Two different configurations of sensors were tested, i.e., with and without pores in the PET substrate. The sensing performance of both sensors has been tested for relative humidity ranging from 35 to 100% at temperatures ranging from 20 to 50 °C. The capacitance of the sensor varies linearly in response to the change in humidity. The sensor with pores shows a response from 28 to 630 pF as the humidity varied from 35 to 100%, whereas the sensor without pores responded from 22 to 430 pF. The response and recovery times of the fabricated sensor are observed as ∼2.4, and ∼1.8 s, respectively, and the sensitivity is 9.67 pF/% RH. The sensors are tested multiple times, and repeatable results are achieved each time with an accuracy of ±0.22%. Further, the sensor's response is also stable for different ranges of temperatures. Finally, to demonstrate an application of the proposed sensor, it has been utilized to monitor respiration through nose and mouth breathing. The low-cost, stable, repeatable, and highly sensitive response makes our fabricated sensor a promising candidate for practical field applications.
Language	English
Publishing date	2023-05-06
Publishing country	United States
Document type	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.3c00448
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Article: Role of Anifrolumab in Refractory Cutaneous Manifestations of Lupus Erythematosus: A Case Series and Literature Review.

Khan, Muhammad Atif / Khan, Faiza Humayun / Khan, Hina Benish / Saadeh, Constantine / Davey, Nichole

Cureus

2023 Volume 15, Issue 5, Page(s) e39553

Abstract: Lupus erythematosus (LE) is an autoimmune disease that presents either as a systemic (SLE) or an isolated skin disease (CLE). Currently, there is no FDA-approved medication specifically for CLE, and is treated with the same approach as SLE. We present ... ...

Abstract	Lupus erythematosus (LE) is an autoimmune disease that presents either as a systemic (SLE) or an isolated skin disease (CLE). Currently, there is no FDA-approved medication specifically for CLE, and is treated with the same approach as SLE. We present two refractory cases of SLE with severe cutaneous manifestations unresponsive to the first-line therapy treated with anifrolumab. First, a 39-year-old Caucasian female with a known history of SLE with severe subacute CLE presented to the clinic for her refractory cutaneous symptoms. Her current regimen was hydroxychloroquine (HCQ), mycophenolate mofetil (MMF), and s/c belimumab with no improvement. Belimumab was discontinued, and she was started on anifrolumab with significant improvement. Another, a 28-year-old female with no known medical history was referred to a rheumatology clinic for elevated anti-nuclear antibody (ANA) and ribonucleoprotein (RNP) titers. She was diagnosed with SLE, and was treated with HCQ, belimumab, and MMF but failed to produce a reasonably good outcome. Hence belimumab was discontinued and anifrolumab was added instead with significant cutaneous improvement. The treatment spectrum for SLE is wide, which includes antimalarial (HCQ), oral corticosteroids (OCS), and immunosuppressants (Methotrexate-MTX, MMF, azathioprine-AZT). Anifrolumab, a type 1 IFNα receptor subunit 1 (IFNAR1) inhibitor, has been recently approved by the FDA for moderate to severe SLE while on standard therapy in August 2021. Early use of anifrolumab in moderate to severe cutaneous manifestations of SLE or CLE may result in significant improvement in patients.
Language	English
Publishing date	2023-05-27
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.39553
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Article ; Online: Democracy's limited impact on innovation: Panel data evidence from developing countries.

Ahmed, Masood / Khan, Muhammad Atif / Attique, Anam / Khan, Muhammad Asif / Haddad, Hossam / Al-Ramahi, Nidal Mahmoud

PloS one

2024 Volume 19, Issue 3, Page(s) e0297915

Abstract: This study investigates the relationship between democracy and innovation across 61 developing countries from 2013 to 2020, utilizing data from Global Innovation Index. Employing the Freedom House Index and Polity2 indicators as proxies for democracy, ... ...

Abstract	This study investigates the relationship between democracy and innovation across 61 developing countries from 2013 to 2020, utilizing data from Global Innovation Index. Employing the Freedom House Index and Polity2 indicators as proxies for democracy, research employs Ordinary Least Squares (OLS), Fixed Effects and SystemGMM techniques to analyze their impact on innovation. The findings of the study reveal no statistically significant relationships between democracy and innovation in developing nations within specified timeframe. Through empirical analysis, including various econometric approaches, it is observed that the level of democracy as measured by these indicators, does not appear to exert a discernable impact on the innovation landscape of these countries. These results carry important implications for public policy. While the promotion of democracy remains a crucial goal, especially for societal development and political stability, this study suggests that solely focusing on enhancing democratic institutions might not necessarily yield immediate direct improvements in the innovation capacities of developing nations. Policymakers and stakeholders involved in fostering innovation ecosystems in these regions may need to consider a more nuanced approach, encompassing factors beyond the scope of democratic governance to effectively spur innovation. Understanding the nuanced relationship between democracy and innovation in developing countries has significant implications for designing targeted policies aimed at enhancing innovation capacities, economic growth and overall societal development in these regions.
MeSH term(s)	Democracy ; Developing Countries ; Ecosystem ; Economic Development ; Freedom
Language	English
Publishing date	2024-03-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0297915
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Article ; Online: The dynamic linkage between globalization, financial development, energy utilization, and environmental sustainability in GCC countries.

Yang, Bo / Jahanger, Atif / Usman, Muhammad / Khan, Muhammad Atif

Environmental science and pollution research international

2021 Volume 28, Issue 13, Page(s) 16568–16588

Abstract: This study investigates the impact of globalization, financial development, and energy utilization on environmental sustainability in the Gulf Cooperation Council (GCC) countries. GCC countries are currently experiencing higher demand and utilization of ... ...

Abstract	This study investigates the impact of globalization, financial development, and energy utilization on environmental sustainability in the Gulf Cooperation Council (GCC) countries. GCC countries are currently experiencing higher demand and utilization of energy resources, high global integration, and improvements in the financial sector that poses serious environmental sustainability challenges. We have employed a relatively comprehensive proxy, i.e., ecological footprint for environmental sustainability and more advanced and robust econometric strategies (second-generation) to examine the impact of globalization, financial development, and energy utilization on environmental sustainability in the GCC countries, which have a significant departure from the extant literature. The results of this study show that globalization, financial development, and energy utilization are significantly deteriorating the environmental quality in the GCC countries. Additionally, in order to account for the national heterogeneity, we have performed country-specific analysis and interestingly, results reveal that globalization, financial development, and energy utilization negatively influence the environmental sustainability in each sample country that is consistent with the findings of overall panel. Furthermore, the findings are robust to various robustness checks that we have performed for checking the reliability of our main findings. This study also offers some useful policy implications to the stakeholder in general and specifically concerning the GCC countries for promoting their environmental sustainability.
MeSH term(s)	Carbon Dioxide ; Economic Development ; Internationality ; Policy ; Reproducibility of Results
Chemical Substances	Carbon Dioxide (142M471B3J)
Language	English
Publishing date	2021-01-02
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-020-11576-4
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Article ; Online: Facile Pressure-Sensitive Capacitive Touch Keypad for a Green Intelligent Human-Machine Interface.

Malik, Muhammad Shumail / Zulfiqar, Muhammad Hamza / Khan, Muhammad Atif / Mehmood, Muhammad Qasim / Massoud, Yehia

Sensors (Basel, Switzerland)

2022 Volume 22, Issue 21

Abstract: There is a great demand for human-machine interfaces (HMIs) in emerging electronics applications. However, commercially available plastic-based HMIs are primarily rigid, application-specific, and hard to recycle and dispose of due to their non- ... ...

Abstract	There is a great demand for human-machine interfaces (HMIs) in emerging electronics applications. However, commercially available plastic-based HMIs are primarily rigid, application-specific, and hard to recycle and dispose of due to their non-biodegradability. This results in electronic and plastic waste, potentially damaging the environment by ending up in landfills and water resources. This work presents a green, capacitive pressure-sensitive (CPS), touch sensor-based keypad as a disposable, wireless, and intelligent HMI to mitigate these problems. The CPS touch keypads were fabricated through a facile green fabrication process by direct writing of graphite-on-paper, using readily available materials such as paper and pencils, etc. The interdigitated capacitive (IDC) touch sensors were optimized by analyzing the number of electrode fingers, dimensions, and spacing between the electrode fingers. The CPS touch keypad was customized to wirelessly control a robotic arm's movements based on the touch input. A low-pressure touch allows slow-speed robotic arm movement for precision movements, and a high-pressure touch allows high-speed robotic arm movement to cover the large movements quickly. The green CPS touch keypad, as a disposable wireless HMI, has the potential to enforce a circular economy by mitigating electronic and plastic waste, which supports the vision of a sustainable and green world.
MeSH term(s)	Humans ; Touch ; Electrodes ; Electronics ; Graphite ; Plastics
Chemical Substances	Graphite (7782-42-5) ; Plastics
Language	English
Publishing date	2022-10-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s22218113
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