LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 50

Search options

  1. Article: An automated and fast system to identify COVID-19 from X-ray radiograph of the chest using image processing and machine learning.

    Khan, Murtaza Ali

    International journal of imaging systems and technology

    2021  Volume 31, Issue 2, Page(s) 499–508

    Abstract: A type of coronavirus disease called COVID-19 is spreading all over the globe. Researchers and scientists are endeavoring to find new and effective methods to diagnose and treat this disease. This article presents an automated and fast system that ... ...

    Abstract A type of coronavirus disease called COVID-19 is spreading all over the globe. Researchers and scientists are endeavoring to find new and effective methods to diagnose and treat this disease. This article presents an automated and fast system that identifies COVID-19 from X-ray radiographs of the chest using image processing and machine learning algorithms. Initially, the system extracts the feature descriptors from the radiographs of both healthy and COVID-19 affected patients using the speeded up robust features algorithm. Then, visual vocabulary is built by reducing the number of feature descriptors via quantization of feature space using the K-means clustering algorithm. The visual vocabulary train the support vector machine (SVM) classifier. During testing, an X-ray radiograph's visual vocabulary is sent to the trained SVM classifier to detect the absence or presence of COVID-19. The study used the dataset of 340 X-ray radiographs, 170 images of each Healthy and Positive COVID-19 class. During simulations, the dataset split into training and testing parts at various ratios. After training, the system does not require any human intervention and can process thousands of images with high precision in a few minutes. The performance of the system is measured using standard parameters of accuracy and confusion matrix. We compared the performance of the proposed SVM-based classier with the deep-learning-based convolutional neural networks (CNN). The SVM yields better results than CNN and achieves a maximum accuracy of up to 94.12%.
    Language English
    Publishing date 2021-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2009087-0
    ISSN 1098-1098 ; 0899-9457
    ISSN (online) 1098-1098
    ISSN 0899-9457
    DOI 10.1002/ima.22564
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article: New Onset Seizures in Hospitalized COVID-19 Patients; A Systematic Review and Meta-Analysis.

    Shamim, Daniah / Ganatra, Fatima / Khan, Murtaza / Gronseth, Gary

    The Neurohospitalist

    2023  Volume 14, Issue 1, Page(s) 34–43

    Abstract: Objective: Seizures in COVID-19 patients continue to be a common reason for consulting the neurology service in the inpatient setting. This paper assesses the frequency of new onset seizures in adult hospitalized COVID-19 patients.: Method: PubMed ... ...

    Abstract Objective: Seizures in COVID-19 patients continue to be a common reason for consulting the neurology service in the inpatient setting. This paper assesses the frequency of new onset seizures in adult hospitalized COVID-19 patients.
    Method: PubMed and EMBASE were searched, with fifteen cohort studies identified to calculate the primary outcome, which was the frequency of new onset seizures in hospitalized COVID-19 patients. An inverse variance meta-analysis of single proportions with a random effects model was applied to these cohort studies to calculate the primary outcome. Risk of bias in individual studies was assessed using the 10-item risk of bias tool for prevalence studies.
    Results: The meta-analysis revealed a frequency of .71% (95% confidential interval: .32-1.25, I
    Conclusion: The frequency of seizures in COVID-19 was .71% (95% confidential interval: .32-1.25). Slightly less than half of COVID-19 patients had head imaging abnormalities as a complication of COVID-19 infection. Only a small percentage of patients with seizures and COVID-19 met the criteria for COVID-19 encephalitis.
    Language English
    Publishing date 2023-09-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2629083-2
    ISSN 1941-8752 ; 1941-8744
    ISSN (online) 1941-8752
    ISSN 1941-8744
    DOI 10.1177/19418744231202317
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Nitric Oxide Acts as a Key Signaling Molecule in Plant Development under Stressful Conditions.

    Khan, Murtaza / Ali, Sajid / Al Azzawi, Tiba Nazar Ibrahim / Yun, Byung-Wook

    International journal of molecular sciences

    2023  Volume 24, Issue 5

    Abstract: Nitric oxide (NO), a colorless gaseous molecule, is a lipophilic free radical that easily diffuses through the plasma membrane. These characteristics make NO an ideal autocrine (i.e., within a single cell) and paracrine (i.e., between adjacent cells) ... ...

    Abstract Nitric oxide (NO), a colorless gaseous molecule, is a lipophilic free radical that easily diffuses through the plasma membrane. These characteristics make NO an ideal autocrine (i.e., within a single cell) and paracrine (i.e., between adjacent cells) signalling molecule. As a chemical messenger, NO plays a crucial role in plant growth, development, and responses to biotic and abiotic stresses. Furthermore, NO interacts with reactive oxygen species, antioxidants, melatonin, and hydrogen sulfide. It regulates gene expression, modulates phytohormones, and contributes to plant growth and defense mechanisms. In plants, NO is mainly produced via redox pathways. However, nitric oxide synthase, a key enzyme in NO production, has been poorly understood recently in both model and crop plants. In this review, we discuss the pivotal role of NO in signalling and chemical interactions as well as its involvement in the mitigation of biotic and abiotic stress conditions. In the current review, we have discussed various aspects of NO including its biosynthesis, interaction with reactive oxygen species (ROS), melatonin (MEL), hydrogen sulfide, enzymes, phytohormones, and its role in normal and stressful conditions.
    MeSH term(s) Nitric Oxide/metabolism ; Melatonin/metabolism ; Hydrogen Sulfide/metabolism ; Reactive Oxygen Species/metabolism ; Plant Growth Regulators/metabolism ; Plants/metabolism ; Plant Development ; Stress, Physiological
    Chemical Substances Nitric Oxide (31C4KY9ESH) ; Melatonin (JL5DK93RCL) ; Hydrogen Sulfide (YY9FVM7NSN) ; Reactive Oxygen Species ; Plant Growth Regulators
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24054782
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Nitric Oxide, a Key Modulator in the Alleviation of Environmental Stress-Mediated Damage in Crop Plants: A Meta-Analysis.

    Khan, Murtaza / Al Azzawi, Tiba Nazar Ibrahim / Ali, Sajid / Yun, Byung-Wook / Mun, Bong-Gyu

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 11

    Abstract: Nitric oxide (NO) is a small, diatomic, gaseous, free radicle, lipophilic, diffusible, and highly reactive molecule with unique properties that make it a crucial signaling molecule with important physiological, biochemical, and molecular implications for ...

    Abstract Nitric oxide (NO) is a small, diatomic, gaseous, free radicle, lipophilic, diffusible, and highly reactive molecule with unique properties that make it a crucial signaling molecule with important physiological, biochemical, and molecular implications for plants under normal and stressful conditions. NO regulates plant growth and developmental processes, such as seed germination, root growth, shoot development, and flowering. It is also a signaling molecule in various plant growth processes, such as cell elongation, differentiation, and proliferation. NO also regulates the expression of genes encoding hormones and signaling molecules associated with plant development. Abiotic stresses induce NO production in plants, which can regulate various biological processes, such as stomatal closure, antioxidant defense, ion homeostasis, and the induction of stress-responsive genes. Moreover, NO can activate plant defense response mechanisms, such as the production of pathogenesis-related proteins, phytohormones, and metabolites against biotic and oxidative stressors. NO can also directly inhibit pathogen growth by damaging their DNA and proteins. Overall, NO exhibits diverse regulatory roles in plant growth, development, and defense responses through complex molecular mechanisms that still require further studies. Understanding NO's role in plant biology is essential for developing strategies for improved plant growth and stress tolerance in agriculture and environmental management.
    Language English
    Publishing date 2023-05-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12112121
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Physiological and Ultrastructural Changes in Dendranthema morifolium Cultivars Exposed to Different Cadmium Stress Conditions

    Luqmān, Muḥammad / Ṣalāḥ al-Dīn / Khan, Asif / Zhou, Yunwei / He, Miao / Alrefaei, Abdulwahed Fahad / Khan, Murtaza / ʻAlī, Sājid

    Agriculture. 2023 Jan. 28, v. 13, no. 2

    2023  

    Abstract: Ornamental plant species may vary substantially in their tolerance response to heavy metals. The aim of this research was to check chrysanthemum cultivars, namely Donglin Ruixue (C), Yellow (F), Red pocket (G), and New 9714 (I), which are commonly used ... ...

    Abstract Ornamental plant species may vary substantially in their tolerance response to heavy metals. The aim of this research was to check chrysanthemum cultivars, namely Donglin Ruixue (C), Yellow (F), Red pocket (G), and New 9714 (I), which are commonly used as landscape plants to determine their levels of cadmium (Cd) tolerance at different cadmium concentrations through hydroponic cultures. Chrysanthemum cultivars were treated with five different Cd concentrations (0, 10, 20, 50, and 100 mg L⁻¹) and different physiological, enzymatic, and ultra-structure traits were taken under consideration in vitro. The results showed that cadmium concentration significantly inhibited the total chlorophyll content, chlorophyll a, chlorophyll b, and carotenoid content. Chlorophyll contents were significantly reduced at higher Cd concentrations in all cultivars, but the reduction rates were higher in cultivar F (59.49%), G (40.41%), I (44.97%), and C (33.86%). Similarly, the chlorophyll b reduction was higher than that of chlorophyll a in I (73.33%), followed by G (58.06%), F (61.66%), and C (32.43%), under Cd stress conditions. Additionally, the relative conductivity was recorded in cultivars C (146.48%), F (223.66%), G (165.96%), and I (154.92%), respectively, at 100 mg L⁻¹ Cd concentrations. Likewise, MDA was significantly increased with high Cd stress, at 155.56, 325.27, 173.91, and 322.18%, in C, F, G, and I cultivars at 100 mg L⁻¹, but it was promoted with a greater increase in F and I cultivars. Similarly, SOD and CAT activities were increased with the increase in Cd stress, but reduced in F and I cultivars at higher stress levels of 100 mg L⁻¹. In the same way, POD activity was significantly higher in the C and G cultivars. Additionally, ultrastructure changes also occurred with the increase in the Cd stress, i.e., 20 mg L⁻¹ to 100 mg L⁻¹, and these changes caused alterations in cell organelles, including in the chloroplast, grana, lamella, thylakoid, and stroma. They also caused noticeable damage to mitochondria at higher Cd concentrations. It was concluded that the higher levels of antioxidative defense of the C and G cultivars of chrysanthemum indicated their ability to tolerate high Cd stress conditions. These could, therefore, be used for their phytoremediation potential in Cd-contaminated areas.
    Keywords Chrysanthemum morifolium ; agriculture ; cadmium ; carotenoids ; chlorophyll ; cultivars ; grana ; hydroponics ; landscapes ; mitochondria ; ornamental plants ; phytoremediation ; thylakoids ; ultrastructure
    Language English
    Dates of publication 2023-0128
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2651678-0
    ISSN 2077-0472
    ISSN 2077-0472
    DOI 10.3390/agriculture13020317
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  6. Article ; Online: The Key Roles of ROS and RNS as a Signaling Molecule in Plant–Microbe Interactions

    Khan, Murtaza / ʻAlī, Sājid / Al Azzawi, Tiba Nazar Ibrahim / Saqib, Saddam / Ullah, Fazal / Ayaz, Asma / Zaman, Wajid

    Antioxidants. 2023 Jan. 25, v. 12, no. 2

    2023  

    Abstract: Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a pivotal role in the dynamic cell signaling systems in plants, even under biotic and abiotic stress conditions. Over the past two decades, various studies have endorsed the notion ... ...

    Abstract Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play a pivotal role in the dynamic cell signaling systems in plants, even under biotic and abiotic stress conditions. Over the past two decades, various studies have endorsed the notion that these molecules can act as intracellular and intercellular signaling molecules at a very low concentration to control plant growth and development, symbiotic association, and defense mechanisms in response to biotic and abiotic stress conditions. However, the upsurge of ROS and RNS under stressful conditions can lead to cell damage, retarded growth, and delayed development of plants. As signaling molecules, ROS and RNS have gained great attention from plant scientists and have been studied under different developmental stages of plants. However, the role of RNS and RNS signaling in plant–microbe interactions is still unknown. Different organelles of plant cells contain the enzymes necessary for the formation of ROS and RNS as well as their scavengers, and the spatial and temporal positions of these enzymes determine the signaling pathways. In the present review, we aimed to report the production of ROS and RNS, their role as signaling molecules during plant–microbe interactions, and the antioxidant system as a balancing system in the synthesis and elimination of these species.
    Keywords abiotic stress ; growth and development ; organelles ; plant growth ; reactive nitrogen species ; reactive oxygen species
    Language English
    Dates of publication 2023-0125
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12020268
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Article: Bioactivity and Therapeutic Potential of Kaempferol and Quercetin: New Insights for Plant and Human Health.

    Jan, Rahmatullah / Khan, Murtaza / Asaf, Sajjad / Lubna / Asif, Saleem / Kim, Kyung-Min

    Plants (Basel, Switzerland)

    2022  Volume 11, Issue 19

    Abstract: Plant secondary metabolites, especially flavonoids, are major metabolites widely found in plants that play several key roles in plant defence and signalling in response to stress conditions. The most studied among these flavonoids are kaempferol and ... ...

    Abstract Plant secondary metabolites, especially flavonoids, are major metabolites widely found in plants that play several key roles in plant defence and signalling in response to stress conditions. The most studied among these flavonoids are kaempferol and quercetin due to their anti-oxidative potential and their key roles in the defence system, making them more critical for plant adaptation in stress environments. Kaempferol and quercetin in plants have great therapeutic potential for human health. Despite being well-studied, some of their functional aspects regarding plants and human health need further evaluation. This review summarizes the emerging potential of kaempferol and quercetin in terms of antimicrobial activity, bioavailability and bioactivity in the human body as well as in the regulation of plant defence in response to stresses and as a signalling molecule in terms of hormonal modulation under stress conditions. We also evaluated the safe use of both metabolites in the pharmaceutical industry.
    Language English
    Publishing date 2022-10-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants11192623
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article: Parthenium hysterophorus

    Khan, Asif / Ali, Sajid / Khan, Murtaza / Hamayun, Muhammad / Moon, Yong-Sun

    Microorganisms

    2022  Volume 10, Issue 11

    Abstract: Parthenium ... ...

    Abstract Parthenium hysterophorus
    Language English
    Publishing date 2022-11-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms10112217
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Melatonin Function and Crosstalk with Other Phytohormones under Normal and Stressful Conditions.

    Khan, Murtaza / Ali, Sajid / Manghwar, Hakim / Saqib, Saddam / Ullah, Fazal / Ayaz, Asma / Zaman, Wajid

    Genes

    2022  Volume 13, Issue 10

    Abstract: Melatonin was discovered in plants in the late nineties, but its role, signaling, and crosstalk with other phytohormones remain unknown. Research on melatonin in plants has risen dramatically in recent years and the role of this putative plant hormone ... ...

    Abstract Melatonin was discovered in plants in the late nineties, but its role, signaling, and crosstalk with other phytohormones remain unknown. Research on melatonin in plants has risen dramatically in recent years and the role of this putative plant hormone under biotic and abiotic stress conditions has been reported. In the present review, we discuss the main functions of melatonin in the growth and development of plants, its role under abiotic stresses, such as water stress (waterlogging and drought), extreme temperature (low and high), salinity, heavy metal, and light-induced stress. Similarly, we also discuss the role of melatonin under biotic stresses (antiviral, antibacterial, and antifungal effects). Moreover, the present review meticulously discusses the crosstalk of melatonin with other phytohormones such as auxins, gibberellic acids, cytokinins, ethylene, and salicylic acid under normal and stressful conditions and reports melatonin receptors and signaling in plants. All these aspects of melatonin suggest that phytomelatonin is a key player in crop improvement and biotic and abiotic stress regulation.
    MeSH term(s) Plant Growth Regulators/pharmacology ; Melatonin ; Receptors, Melatonin ; Antifungal Agents/pharmacology ; Plants ; Cytokinins ; Ethylenes/pharmacology ; Indoleacetic Acids ; Anti-Bacterial Agents/pharmacology ; Antiviral Agents/pharmacology ; Salicylates/pharmacology
    Chemical Substances Plant Growth Regulators ; Melatonin (JL5DK93RCL) ; Receptors, Melatonin ; Antifungal Agents ; Cytokinins ; Ethylenes ; Indoleacetic Acids ; Anti-Bacterial Agents ; Antiviral Agents ; Salicylates
    Language English
    Publishing date 2022-09-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes13101699
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: An unusual pigmented lesion.

    Khan, Murtaza / Ahmed, Abir E / Ahmad Z, Zahoor / El Bahtimi, Reem

    International journal of dermatology

    2022  Volume 62, Issue 6, Page(s) 749–751

    MeSH term(s) Humans ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology
    Language English
    Publishing date 2022-10-22
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16470
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top