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  1. AU="Khan, Tazeen"
  2. AU="Adzhubei, Ivan A"
  3. AU="Alicia Reyes-Arellano"
  4. AU="L. Marcus Wilhelmsson"
  5. AU=Filocamo Giovanni
  6. AU="Andrea Terán-Valdez"
  7. AU=Cleverley Joanne AU=Cleverley Joanne
  8. AU="Feng, Shiguang"
  9. AU="De Falco, Antonio"
  10. AU="Plenter, R J"
  11. AU="Malarz, Janusz"

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  1. Artikel: Gut Brain axis: The gut microbiome in peri-operative medicine.

    Khan, Tazeen / Khanna, Puneet / Pangasa, Neha

    Indian journal of anaesthesia

    2023  Band 67, Heft 2, Seite(n) 235–236

    Sprache Englisch
    Erscheinungsdatum 2023-02-16
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/ija.ija_557_22
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Management of giant adrenal pseudocyst in pregnancy - A unique approach and review of literature.

    Khan, Tazeen / Sabu, Brinda / Ranganayaki, Vidyalekshmy / Rafeekha, P / Thomas, Renu

    Obstetric medicine

    2022  Band 16, Heft 1, Seite(n) 52–55

    Abstract: Pseudocysts of the adrenal gland are rare and in the majority of cases are non- functioning. They become symptomatic only when they are complicated by hormonal excess, rupture, haemorrhage or infection. Described here is a 26-year-old woman who developed ...

    Abstract Pseudocysts of the adrenal gland are rare and in the majority of cases are non- functioning. They become symptomatic only when they are complicated by hormonal excess, rupture, haemorrhage or infection. Described here is a 26-year-old woman who developed an acute abdomen at 28 weeks of gestation due to a left adrenal haemorrhagic pseudocyst. A conservative approach was adopted, which was followed by elective term caesarean delivery with surgical intervention at the same time. The described case is unique in terms of strategizing timing and mode of management and thus minimizing the risk of prematurity and maternal morbidity associated with interval surgery.
    Sprache Englisch
    Erscheinungsdatum 2022-04-07
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2612229-7
    ISSN 1753-4968 ; 1753-495X
    ISSN (online) 1753-4968
    ISSN 1753-495X
    DOI 10.1177/1753495X221089210
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Congenital Intracranial Teratoma—An Intractable Enigma: A Case Report and Review of Literature

    Sabu, Brinda / Khan, Tazeen / Vidyalekshmy, R / Jain, Naveen

    Journal of Fetal Medicine

    2021  Band 08, Heft 03, Seite(n) 231–235

    Abstract: Congenital intracranial tumors are rare, accounting for 0.5–1.9% of pediatric tumors. Though antenatal detection rates have improved with ultrasound (US) and MRI, histopathology gives a definite diagnosis. Prognosis is guarded as there is no effective ... ...

    Abstract Congenital intracranial tumors are rare, accounting for 0.5–1.9% of pediatric tumors. Though antenatal detection rates have improved with ultrasound (US) and MRI, histopathology gives a definite diagnosis. Prognosis is guarded as there is no effective postnatal treatment. We present a fetus incidentally diagnosed with intracranial teratoma by US and MRI at 36 weeks of gestation. Elective cesarean was performed for anticipated labor dystocia. A female baby with head circumference > 99th centile was delivered. Due to the invasive growth potential of the tumor, the baby succumbed at 4 months of palliative care. Further research is required for devising new treatment modalities to tackle this intractable condition.
    Schlagwörter Prenatal intracranial tumor ; Congenital intracranial teratoma ; Fetal MRI ; Mature teratoma ; Brain neoplasms
    Sprache Englisch
    Erscheinungsdatum 2021-09-01
    Verlag Thieme Medical and Scientific Publishers Pvt. Ltd.
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2806650-9
    ISSN 2348-8859 ; 2348-1153
    ISSN (online) 2348-8859
    ISSN 2348-1153
    DOI 10.1007/s40556-021-00314-6
    Datenquelle Thieme Verlag

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  4. Artikel: Author's reply.

    Khan, Zahid A / Singh, Chanpreet / Khan, Tazeen

    Journal of family & community medicine

    2019  Band 26, Heft 2, Seite(n) 144–145

    Sprache Englisch
    Erscheinungsdatum 2019-05-09
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2580509-5
    ISSN 2229-340X ; 1319-1683
    ISSN (online) 2229-340X
    ISSN 1319-1683
    DOI 10.4103/2230-8229.257312
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Association between baseline insulin resistance and hospital mortality in moderate-to-severe coronavirus disease 2019 patients without diabetes mellitus: An observational study.

    Khan, Tazeen / Naagar, Shilpa / Nair, Parvathy R / Haritha, Damarla / Yadav, Preeti / Datta, Sudip Kumar / Bhattacharjee, Sulagna / Gupta, Yashdeep / Baidya, Dalim Kumar / Anand, Rahul Kumar / Ray, Bikash Ranjan / Ansari, Shiba / Subramaniam, Rajeshwari / Maitra, Souvik

    International journal of critical illness and injury science

    2024  Band 14, Heft 1, Seite(n) 26–31

    Abstract: Background: Insulin resistance is often implicated as a risk factor of cell-mediated immune dysfunction in sepsis patients and results in poor clinical outcome. However, it is unclear whether early insulin resistance is contributory to T-cell ... ...

    Abstract Background: Insulin resistance is often implicated as a risk factor of cell-mediated immune dysfunction in sepsis patients and results in poor clinical outcome. However, it is unclear whether early insulin resistance is contributory to T-cell dysfunction and poor clinical outcome in coronavirus disease 2019 (COVID-19) patients.
    Methods: Adult patients with moderate-to-severe or critically ill COVID-19 infection were included in this study. Serum samples were collected at the time of diagnosis for fasting plasma glucose, serum insulin, serum cortisol, and serum glucagon measurements, and the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) score was calculated.
    Results: One hundred and twenty-six subjects with a mean (standard deviation) age of 49.6 (16.3) years were recruited in this study, and 62.4% (78 of 125 patients) were male. HOMA-IR was a predictor of inhospital mortality with the area under the receiver operating characteristics curve (AUROC) (95% confidence interval [CI] of 0.61 [0.49-0.73]). With a cutoff value of 1.91, sensitivity was 75.5% and specificity was 45.2%. Higher serum insulin was associated with higher survival with AUROC (95% CI) of 0.65 (0.53-0.76), and the best cutoff was 7.15, with a sensitivity and specificity of 62.1% and 64.5%. Serum cortisol was also a predictor of inhospital mortality with an AUROC (95% CI) of 0.67 (0.56-0.77).
    Conclusion: An independent association between baseline serum cortisol and poor outcome in moderate-to-severe COVID-19 patients was observed. Hyperglycemia and HOMA-IR can also predict poor outcome in these patients with some accuracy.
    Sprache Englisch
    Erscheinungsdatum 2024-03-27
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2638865-0
    ISSN 2231-5004 ; 2229-5151
    ISSN (online) 2231-5004
    ISSN 2229-5151
    DOI 10.4103/ijciis.ijciis_41_23
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Subphenotypes of SARS-CoV-2-Associated ARDS Overlap Each Other: A Retrospective Analysis.

    Nair, Parvathy R / Girish, Kavitha / Mini, Gouri / Khan, Tazeen / Haritha, Damarla / Sanyal, Koninica / Bhattacharjee, Sulagna / Baidya, Dalim K / Ray, Bikash R / Anand, Rahul K / Datta, Sudip K / Soneja, Manish / Subramaniam, Rajeshwari / Maitra, Souvik

    Journal of laboratory physicians

    2023  Band 15, Heft 4, Seite(n) 558–561

    Abstract: ... ...

    Abstract Background
    Sprache Englisch
    Erscheinungsdatum 2023-07-03
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727
    ISSN (online) 0974-7826
    ISSN 0974-2727
    DOI 10.1055/s-0043-1768952
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  7. Artikel: Correlates of physical disability in the elderly population of Rural North India (Haryana).

    Khan, Zahid A / Singh, Chanpreet / Khan, Tazeen

    Journal of family & community medicine

    2016  Band 25, Heft 3, Seite(n) 199–204

    Abstract: Background: With the increase in life expectancy, the number of older persons is constantly rising. Disability rates for elderly people are also on the rise with an increase in the burden of chronic diseases depriving them of independence and the ... ...

    Abstract Background: With the increase in life expectancy, the number of older persons is constantly rising. Disability rates for elderly people are also on the rise with an increase in the burden of chronic diseases depriving them of independence and the performance of activities of daily living. The study aimed to estimate the prevalence of physical disability and determine its correlates among elderly population of rural Haryana.
    Materials and methods: A community-based cross-sectional study was conducted among 322 elderly participants aged 60 years and above in the rural area of Haryana, India. Data pertaining to sociodemographic profile, self-reported chronic diseases/ailments, and disability assessment by means of Barthel and Katz index of activities of daily living was collected and analyzed.
    Results: Overall, 21.4% and 18% elderly people had some form of disability according to the Barthel index and Katz index, respectively. With aging, disability increased and 52.5% of the elderly aged 75 years and above were found to have disability according to the Barthel's index. Females (
    Conclusion: Disability is associated with increasing age and an increase in the burden of chronic health ailments in the elderly. Consequently, there is the need to prioritize preventive, promotive, curative, and rehabilitative services for the geriatric population.
    Sprache Englisch
    Erscheinungsdatum 2016-05-25
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2580509-5
    ISSN 2229-340X ; 1319-1683
    ISSN (online) 2229-340X
    ISSN 1319-1683
    DOI 10.4103/jfcm.JFCM_160_17
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Development of an institutional protocol for percutaneous dilatational tracheostomy in critically ill COVID-19 patients: Initial experience.

    Damarla, Haritha / Pangasa, Neha / Hirolli, Divya / Jha, Parthadeep / Garg, Heena / Khan, Tazeen / Soni, Lipika / Maitra, Souvik / Anand, Rahul K / Ray, Bikash R / Baidya, Dalim K

    Journal of anaesthesiology, clinical pharmacology

    2022  Band 38, Heft Suppl 1, Seite(n) S102–S106

    Abstract: Background and aims: Percutaneous dilatational tracheostomy (PDT) may improve the outcome in critically ill COVID-19 patients on mechanical ventilation. However, the timing of performing tracheostomy may be controversial, and it is an aerosol-generating ...

    Abstract Background and aims: Percutaneous dilatational tracheostomy (PDT) may improve the outcome in critically ill COVID-19 patients on mechanical ventilation. However, the timing of performing tracheostomy may be controversial, and it is an aerosol-generating procedure with a potential risk of viral exposure to healthcare workers.
    Material and methods: An operational protocol for performing PDT was made and subsequently followed in a designated COVID-19 ICU. Critically ill adult patients on mechanical ventilators who underwent PDT were included in this retrospective cohort study. Case files were retrospectively reviewed and patient characteristics, clinical outcome, and procedure-related details were noted.
    Results: Forty-one patients were included in the analysis. The median age was 49 (39-67) years, and 41.5% of patients were females. The median duration of mechanical ventilation before tracheostomy was 10 (8-16) days, and the median (IQR) PaO
    Conclusion: This descriptive study demonstrates the feasibility, implementation, and apparent safety of the PDT protocol developed at our institution.
    Sprache Englisch
    Erscheinungsdatum 2022-06-15
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 1401760-x
    ISSN 0970-9185
    ISSN 0970-9185
    DOI 10.4103/joacp.joacp_495_21
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

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  9. Artikel: Subphenotypes of SARS-CoV-2-Associated ARDS Overlap Each Other: A Retrospective Analysis

    Nair, Parvathy R. / Girish, Kavitha / Mini, Gouri / Khan, Tazeen / Haritha, Damarla / Sanyal, Koninica / Bhattacharjee, Sulagna / Baidya, Dalim K. / Ray, Bikash R. / Anand, Rahul K. / Datta, Sudip K. / Soneja, Manish / Subramaniam, Rajeshwari / Maitra, Souvik

    Journal of Laboratory Physicians

    2023  Band 15, Heft 04, Seite(n) 558–561

    Abstract: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-associated pneumonia and acute respiratory distress syndrome (ARDS) were often associated with hyperinflammation and elevation of several serum inflammatory markers but ... ...

    Abstract Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-associated pneumonia and acute respiratory distress syndrome (ARDS) were often associated with hyperinflammation and elevation of several serum inflammatory markers but usually less than what is observed in non-coronavirus disease (COVID) ARDS. Elevated inflammatory markers such as C-reactive protein, interleukin (IL)-6, etc., are associated with severe infection. This study identified subphenotypes of COVID-19 ARDS patients by latent profile analysis in a cohort of Indian patients.
    Methods: Data of n  = 233 adult Indian patients with laboratory-confirmed SARS-CoV-2 infection admitted to a tertiary care teaching hospital were analyzed in this retrospective study. Only patients with acute respiratory failure (defined by partial pressure of oxygen/fraction of inspired oxygen ratio < 200 mm Hg) and chest X-ray showing bilateral infiltrates were included.
    Results: The patients' mean (standard deviation) age was 53.3 (14.9) years, and 62% were male. A two subphenotypic model was formulated based on the lowest Bayesian information criterion. Neutrophil-to-lymphocyte ratio and serum IL-6 were latent variables in that model (entropy 0.91). The second phenotype (hyperinflammatory) had lower platelet count ( p  = 0.02), higher serum creatinine ( p  = 0.004), higher C-reactive protein ( p  = 0.001), higher ferritin ( p  < 0.001), and serum lactate dehydrogenase ( p  = 0.009). Age-adjusted hospital mortality ( p  = 0.007), duration of hospital stay ( p  < 0.001), and duration of intensive care unit stay ( p  < 0.001) were significantly higher in the second subphenotype.
    Conclusion: Two distinct but overlapping subphenotypes were identified in SARS-CoV-2-associated respiratory failure. Hyperinflammatory subphenotype was associated with significantly poor short-term outcomes.
    Schlagwörter ARDS ; COVID-19 ; SARS-CoV-2 ; latent class
    Sprache Englisch
    Erscheinungsdatum 2023-07-03
    Verlag Thieme Medical and Scientific Publishers Pvt. Ltd.
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2461120-7
    ISSN 0974-7826 ; 0974-2727 ; 0974-7826
    ISSN (online) 0974-7826
    ISSN 0974-2727 ; 0974-7826
    DOI 10.1055/s-0043-1768952
    Datenquelle Thieme Verlag

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