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  1. Article ; Online: Quadricuspid aortic valve.

    Jain, Akash / Kharge, Jayashree / Manjunath, Cholanahalli Nanjappa / Shrimanth, Yamasandi Siddegowda

    The Journal of invasive cardiology

    2023  Volume 35, Issue 9

    Abstract: A 56-year-old man presented with typical angina for 1 day and a prior history of exertional dyspnea of 6 months duration. Clinically, he was diagnosed with severe aortic regurgitation (AR). Electrocardiogram showed left ventricular hypertrophy with ... ...

    Abstract A 56-year-old man presented with typical angina for 1 day and a prior history of exertional dyspnea of 6 months duration. Clinically, he was diagnosed with severe aortic regurgitation (AR). Electrocardiogram showed left ventricular hypertrophy with volume overload.
    MeSH term(s) Male ; Humans ; Middle Aged ; Quadricuspid Aortic Valve ; Angina Pectoris ; Aortic Valve Insufficiency/diagnosis ; Aortic Valve Insufficiency/etiology ; Aortic Valve Insufficiency/surgery ; Dyspnea ; Electrocardiography
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
    DOI 10.25270/jic/22.00325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Percutaneous Closure of Bilateral Pulmonary Artery Aneurysms in Behcet's Disease.

    Kharge, Jayashree L / M, Usha K / M L, Jayranganath / Newaskar, Aditi A / Shetty, Ananya U / Sridhar, Sastry L

    JACC. Case reports

    2024  Volume 29, Issue 11, Page(s) 102341

    Abstract: Behcet's disease is a multisystemic vasculitis. It can affect the pulmonary artery in 2% to 5% cases. We discuss a case of a young male diagnosed with Behcet's disease on immunosuppressive therapy who presented with bilateral pulmonary artery aneurysms ... ...

    Abstract Behcet's disease is a multisystemic vasculitis. It can affect the pulmonary artery in 2% to 5% cases. We discuss a case of a young male diagnosed with Behcet's disease on immunosuppressive therapy who presented with bilateral pulmonary artery aneurysms which were closed with covered stent and other devices.
    Language English
    Publishing date 2024-04-18
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2024.102341
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  3. Article ; Online: Indicators and predictors of in-hospital mortality and survival in patients with ventricular septal rupture.

    Kharge, Jayashree / Parikh, Chirag Jagdish / Suranagi, Manohar Jayadevappa / Lakshmanasastry, Sridhar / Srinivasa, Kikkeri Hemanasetty / Manjunath, Cholanahalli Nanjappa

    American heart journal plus : cardiology research and practice

    2022  Volume 13, Page(s) 100095

    Abstract: Background: Ventricular septal rupture (VSR), a mechanical complication of myocardial infarction (MI), usually presents with rapid clinical deterioration with acute heart failure or cardiogenic shock. VSR may occur within 24 h to several days after MI ... ...

    Abstract Background: Ventricular septal rupture (VSR), a mechanical complication of myocardial infarction (MI), usually presents with rapid clinical deterioration with acute heart failure or cardiogenic shock. VSR may occur within 24 h to several days after MI and can occur in both anterior and inferior wall MI. Although guidelines recommend emergent surgery, this is associated with a high mortality rate of up to 40%. Intra-aortic balloon pump (IABP) and extracorporeal membrane oxygenation (ECMO) stabilize patients in preparation for angiography and surgery. Delayed surgery allows better septal repair in scarring tissue but also carries the risk of rupture extension and death while waiting. Percutaneous closure of the defect with appropriately designed devices results in better survival in the subacute phase.
    Aims: To study the indicators and predictors of VSR in the current era of primary percutaneous coronary interventions and mechanical circulatory support.
    Methods: Of total of 34,681 patients presenting with MI, the incidence of VSR was 0.45%. We sought to evaluate the predictors of survival and death in VSR. Coronary angiography (CAG) was performed, hemodynamic support provided to unstable patients, and consenting patients were referred to definitive therapy, either surgery or percutaneous device closure. The previously postulated hypotheses of triple vessel disease (TVD), diabetes mellitus (DM), and concentric left ventricular hypertrophy (LVH) due to Hypertension (HTN) being protective against VSR were explored.
    Results: Of the 169 patients with VSR, we found that the group that survived was mostly men and the mean age was 61.5 years; this was in contrast to the non-survivors, who were mainly women, and the mean age was 65.2 years (
    Conclusion: Prevention of myocardial infarction is more important than managing a VSR, which carries a high mortality despite advanced mechanical support and definitive interventional therapy such as emergent surgery and percutaneous device closure.
    Language English
    Publishing date 2022-02-07
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6022
    ISSN (online) 2666-6022
    DOI 10.1016/j.ahjo.2022.100095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Dual-artery stenting of a type III single coronary artery from right aortic sinus.

    Patil, Shivanad / Kharge, Jayashree / Ramlingam, Rangaraj / Kasamsetty, Subramanyam

    Indian heart journal

    2015  Volume 67 Suppl 3, Page(s) S39–40

    Abstract: A single coronary artery presenting with stenosis in two of the three vessels arising from a common ostium is a rare anomaly Lipton et al. proposed a classification, which was modified by Yamanaka and Hobbs. In our case, a single coronary artery was ... ...

    Abstract A single coronary artery presenting with stenosis in two of the three vessels arising from a common ostium is a rare anomaly Lipton et al. proposed a classification, which was modified by Yamanaka and Hobbs. In our case, a single coronary artery was giving rise to the LAD, left circumflex (LCx), and the right coronary artery (RCA). There was 80% stenosis in the ostium of the LCx. The RCA in the mid and distal segment had stenosis of 80% and 70%, respectively. We were able to successfully stent the three stenotic segments.
    MeSH term(s) Coronary Angiography ; Coronary Stenosis/diagnostic imaging ; Coronary Stenosis/surgery ; Coronary Vessel Anomalies/complications ; Coronary Vessel Anomalies/diagnostic imaging ; Humans ; Male ; Middle Aged ; Stents ; Tomography, X-Ray Computed
    Language English
    Publishing date 2015-12
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 604366-5
    ISSN 0019-4832
    ISSN 0019-4832
    DOI 10.1016/j.ihj.2015.11.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cricket ball in the heart? Ball-like thrombus or a thrombus-like mass in the left atrium.

    Kharge, Jayashree / Setty, Natraj / Ravindranath, Nishanth / Ramegowda, Raghu Thagachagere

    European heart journal

    2016  Volume 37, Issue 29, Page(s) 2384

    Language English
    Publishing date 2016-08-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehw176
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    Zs.MO 640: Show issues

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  6. Article: Gender Differences in South Indians with Premature Coronary Artery Disease (< 40 Years)—Insights from the PCAD Registry

    Shetty, Laxmi H. / Patil, Rahul S. / Kharge, Jayashree / Vijay Kumar, J. R. / Ghosh, Santu / Manjunath, C. N.

    Indian Journal of Cardiovascular Disease in Women - WINCARS

    2021  Volume 06, Issue 03, Page(s) 176–183

    Abstract: Introduction: Coronary artery disease (CAD) follows a different pattern in women and men, more so in the young (< 40 years). The gender differences in the risk factors, clinical presentation and diagnosis need to be understood, so that appropriate and ... ...

    Abstract Introduction: Coronary artery disease (CAD) follows a different pattern in women and men, more so in the young (< 40 years). The gender differences in the risk factors, clinical presentation and diagnosis need to be understood, so that appropriate and timely treatment can be given.
    Objective: The study contemplates to analyze the gender differences in the presence of major coronary risk factors, clinical presentation, diagnosis and immediate outcomes in patients who present with premature CAD (PCAD).
    Patients and Methods: We evaluated 1,062 consecutive registry patients who presented with diagnosis of PCAD between 2018 to 2019 at our institution after satisfying the inclusion criteria.
    Results: The study analyses 82 females and 980 males. The mean age of females was 35.4 ± 4.68 years and males was 34.2 ± 4.25 years. Males smoked more often (55.1%, p  < 0.001). Females more often had abnormal BMI (84.1%, p  < 0.001), increased waist-hip ratios (97.6%, p  < 0.001), diabetes (35.4%, p  < 0.001), dyslipidemia (17.1% vs. 11%) and hypertension (15.9% vs. 11.5%). STEMI was the most common presentation among males (80.4% vs. 71.9%). Majority of females (74.6%) presented 6 hours after index pain. NSTEMI was more common among females (20.7% vs. 16%). Single-vessel involvement was common in both sexes (84.1% in males and 85.2% in females). Obstructive CAD was less common in both groups.
    Conclusions: Conventional risk factors play a major role for CAD in Indians. Smoking was common in males and metabolic syndrome in females. Also, females had a higher threshold for seeking treatment and referral. Measures have to be taken for early diagnosis and referral of females. Recanalized and thrombotic coronaries were common, indicating predominant thrombus burden in the young
    Keywords conventional risk factors ; recanalized coronaries ; thrombus ; gender differences ; premature CAD
    Language English
    Publishing date 2021-07-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2455-7854
    ISSN (online) 2455-7854
    DOI 10.1055/s-0041-1736249
    Database Thieme publisher's database

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  7. Article: Coronary stent concertina in proximal left anterior descending artery: An unusual case.

    Patil, Shivanand / Setty, Natraj / Ramalingam, Rangaraj / Kharge, Jayashree / Manjunath, Cholenahally Nanjappa

    Interventional medicine & applied science

    2017  Volume 9, Issue 2, Page(s) 112–115

    Abstract: Since the emergence of stents, there has been persistent improvement in flexibility and deliverability of stents with modifications in its design and number of connectors. This has unfortunately created negative effect on longitudinal strength of stent ... ...

    Abstract Since the emergence of stents, there has been persistent improvement in flexibility and deliverability of stents with modifications in its design and number of connectors. This has unfortunately created negative effect on longitudinal strength of stent resulting into a recently recognized and unaccustomed complication, longitudinal stent deformation (LSD). It is an abrupt shortening of the stent along its longitudinal axis, usually after deployment, due to various reasons. We present a case of LSD in Promus Element stent implanted at proximal left anterior descending artery. The stent shortening was about 25%-30% of its actual length. As this led to exposure of a part of lesion, it was successfully managed by overlapping another stent.
    Language English
    Publishing date 2017-08-30
    Publishing country Hungary
    Document type Case Reports
    ZDB-ID 2573851-3
    ISSN 2061-5094 ; 2061-1617
    ISSN (online) 2061-5094
    ISSN 2061-1617
    DOI 10.1556/1646.9.2017.2.19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Incidental Detection of Arteria Lusoria During Transradial Coronary Intervention.

    Moorthy, Nagaraja / Setty, Natraj / Kharge, Jayashree / Raghu, Thagachagere R / Nanjappa, Manjunath C

    The Journal of invasive cardiology

    2017  Volume 29, Issue 8, Page(s) E90–E91

    Abstract: Transradial access has become popular and preferred approach in coronary interventions due to high success rate, low risk of complications and patients' comfort. However various anatomical variations and anomalies may pose technical challenge. Arteria ... ...

    Abstract Transradial access has become popular and preferred approach in coronary interventions due to high success rate, low risk of complications and patients' comfort. However various anatomical variations and anomalies may pose technical challenge. Arteria lusoria is an uncommon condition which is technically challenging and may warrant cross-over to alternate access. We report a middle aged male presenting with acute coronary syndrome in which arteria lusoria was incidentally detected during right transradial coronary intervention.
    Language English
    Publishing date 2017-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
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  9. Article: Tendon xanthomas as indicators of atherosclerotic burden on coronary arteries.

    Patil, Shivanand / Kharge, Jayashree / Bagi, Vittal / Ramalingam, Rangaraj

    Indian heart journal

    2013  Volume 65, Issue 4, Page(s) 491–492

    Abstract: The presence of tendon xanthomas is an almost certain indicator of familial hypercholesterolemia (FH). They also reflect coronary atherosclerotic burden and therefore must be treated aggressively. Tendon xanthomas also occur in two rare conditions, ... ...

    Abstract The presence of tendon xanthomas is an almost certain indicator of familial hypercholesterolemia (FH). They also reflect coronary atherosclerotic burden and therefore must be treated aggressively. Tendon xanthomas also occur in two rare conditions, cerebrotendinous xanthomatosis and sitosterolemia, which are not easily confused with FH, can be easily differentiated with clinical history and biochemical tests.
    MeSH term(s) Coronary Angiography ; Coronary Disease/diagnosis ; Diagnosis, Differential ; Exercise Test ; Humans ; Hyperlipoproteinemia Type II/diagnosis ; Hyperlipoproteinemia Type II/drug therapy ; Male ; Tendons ; Xanthomatosis/diagnosis ; Young Adult
    Language English
    Publishing date 2013-07-06
    Publishing country India
    Document type Case Reports ; Journal Article
    ZDB-ID 604366-5
    ISSN 0019-4832
    ISSN 0019-4832
    DOI 10.1016/j.ihj.2013.06.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Intracoronary dehiscence of radiopaque ring of a guiding catheter and its retrieval.

    Kharge, Jayashree / Bharatha, Ashalatha / Ramegowda, Raghu Thagachagere

    The Journal of invasive cardiology

    2012  Volume 24, Issue 9, Page(s) E182–4

    Abstract: Intracoronary dehiscence of the radiopaque ring of a guiding catheter is a rare complication, which could lead to myocardial infarction, emergency surgery, or even death. We describe the percutaneous retrieval of the catheter material from the right ... ...

    Abstract Intracoronary dehiscence of the radiopaque ring of a guiding catheter is a rare complication, which could lead to myocardial infarction, emergency surgery, or even death. We describe the percutaneous retrieval of the catheter material from the right coronary artery, thus avoiding surgery and related complications.
    MeSH term(s) Angioplasty, Balloon, Coronary/adverse effects ; Angioplasty, Balloon, Coronary/methods ; Catheterization/adverse effects ; Catheterization/instrumentation ; Coronary Angiography ; Coronary Vessels/pathology ; Coronary Vessels/surgery ; Female ; Humans ; Middle Aged ; Myocardial Infarction/surgery ; Surgical Wound Dehiscence/diagnosis
    Language English
    Publishing date 2012-09
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
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