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  1. Article: Music of metagenomics—a review of its applications, analysis pipeline, and associated tools [Erratum: February 2022, v.22(1); p.137]

    Wajid, Bilal / Anwar, Faria / Wajid, Imran / Nisar, Haseeb / Meraj, Sharoze / Zafar, Ali / Al-Shawaqfeh, Mustafa Kamal / Ekti, Ali Riza / Khatoon, Asia / Suchodolski, Jan S.

    Functional & integrative genomics. 2022 Feb., v. 22, no. 1

    2022  

    Abstract: This humble effort highlights the intricate details of metagenomics in a simple, poetic, and rhythmic way. The paper enforces the significance of the research area, provides details about major analytical methods, examines the taxonomy and assembly of ... ...

    Abstract This humble effort highlights the intricate details of metagenomics in a simple, poetic, and rhythmic way. The paper enforces the significance of the research area, provides details about major analytical methods, examines the taxonomy and assembly of genomes, emphasizes some tools, and concludes by celebrating the richness of the ecosystem populated by the “metagenome.”
    Keywords ecosystems ; genome ; metagenomics ; music ; taxonomy
    Language English
    Dates of publication 2022-02
    Size p. 3-26.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 2014670-X
    ISSN 1438-7948 ; 1438-793X
    ISSN (online) 1438-7948
    ISSN 1438-793X
    DOI 10.1007/s10142-021-00810-y
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5230: Show issues Location:
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  2. Article ; Online: Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases.

    Nisar, Haseeb / Wajid, Bilal / Shahid, Samiah / Anwar, Faria / Wajid, Imran / Khatoon, Asia / Sattar, Mian Usman / Sadaf, Saima

    Experimental biology and medicine (Maywood, N.J.)

    2021  Volume 246, Issue 24, Page(s) 2610–2617

    Abstract: Rare diseases affect nearly 300 million people globally with most patients aged five or less. Traditional diagnostic approaches have provided much of the diagnosis; however, there are limitations. For instance, simply inadequate and untimely diagnosis ... ...

    Abstract Rare diseases affect nearly 300 million people globally with most patients aged five or less. Traditional diagnostic approaches have provided much of the diagnosis; however, there are limitations. For instance, simply inadequate and untimely diagnosis adversely affects both the patient and their families. This review advocates the use of whole genome sequencing in clinical settings for diagnosis of rare genetic diseases by showcasing five case studies. These examples specifically describe the utilization of whole genome sequencing, which helped in providing relief to patients via correct diagnosis followed by use of precision medicine.
    MeSH term(s) Humans ; Rare Diseases/diagnosis ; Rare Diseases/genetics ; Whole Genome Sequencing/methods
    Language English
    Publishing date 2021-09-15
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.1177/15353702211040046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Correction to: Music of metagenomics-a review of its applications, analysis pipeline, and associated tools.

    Wajid, Bilal / Anwar, Faria / Wajid, Imran / Nisar, Haseeb / Meraj, Sharoze / Zafar, Ali / Al-Shawaqfeh, Mustafa Kamal / Ekti, Ali Riza / Khatoon, Asia / Suchodolski, Jan S

    Functional & integrative genomics

    2021  Volume 22, Issue 1, Page(s) 137

    Language English
    Publishing date 2021-11-01
    Publishing country Germany
    Document type Published Erratum
    ZDB-ID 2014670-X
    ISSN 1438-7948 ; 1438-793X
    ISSN (online) 1438-7948
    ISSN 1438-793X
    DOI 10.1007/s10142-021-00820-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Music of metagenomics-a review of its applications, analysis pipeline, and associated tools.

    Wajid, Bilal / Anwar, Faria / Wajid, Imran / Nisar, Haseeb / Meraj, Sharoze / Zafar, Ali / Al-Shawaqfeh, Mustafa Kamal / Ekti, Ali Riza / Khatoon, Asia / Suchodolski, Jan S

    Functional & integrative genomics

    2021  Volume 22, Issue 1, Page(s) 3–26

    Abstract: This humble effort highlights the intricate details of metagenomics in a simple, poetic, and rhythmic way. The paper enforces the significance of the research area, provides details about major analytical methods, examines the taxonomy and assembly of ... ...

    Abstract This humble effort highlights the intricate details of metagenomics in a simple, poetic, and rhythmic way. The paper enforces the significance of the research area, provides details about major analytical methods, examines the taxonomy and assembly of genomes, emphasizes some tools, and concludes by celebrating the richness of the ecosystem populated by the "metagenome."
    MeSH term(s) High-Throughput Nucleotide Sequencing ; Metagenome ; Metagenomics/methods ; Software
    Language English
    Publishing date 2021-10-18
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2014670-X
    ISSN 1438-7948 ; 1438-793X
    ISSN (online) 1438-7948
    ISSN 1438-793X
    DOI 10.1007/s10142-021-00810-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Identification and characterization of plasma membrane aquaporins isolated from fiber cells of Calotropis procera.

    Aslam, Usman / Khatoon, Asia / Cheema, Hafiza Masooma Naseer / Bashir, Aftab

    Journal of Zhejiang University. Science. B

    2013  Volume 14, Issue 7, Page(s) 586–595

    Abstract: Calotropis procera, commonly known as "milkweed", possesses long seed trichomes for seed dispersal and has the ability to survive under harsh conditions such as drought and salinity. Aquaporins are water channel proteins expressed in all land plants, ... ...

    Abstract Calotropis procera, commonly known as "milkweed", possesses long seed trichomes for seed dispersal and has the ability to survive under harsh conditions such as drought and salinity. Aquaporins are water channel proteins expressed in all land plants, divided into five subfamilies plasma membrane intrinsic proteins (PIPs), tonoplast intrinsic proteins (TIPs), NOD26-like proteins (NIPs), small basic intrinsic proteins (SIPs), and the unfamiliar X intrinsic proteins (XIPs). PIPs constitute the largest group of water channel proteins that are involved in different developmental and regulatory mechanisms including water permeability, cell elongation, and stomata opening. Aquaporins are also involved in abiotic stress tolerance and cell expansion mechanisms, but their role in seed trichomes (fiber cells) has never been investigated. A large number of clones isolated from C. procera fiber cDNA library showed sequence homology to PIPs. Both expressed sequence tags (ESTs) and real-time polymerase chain reaction (PCR) studies revealed that the transcript abundance of this gene family in fiber cells of C. procera is greater than that of cotton. Full-length cDNAs of CpPIP1 and CpPIP2 were isolated from C. procera fiber cDNA library and used for constructing plant expression vectors under constitutive (2×35S) and trichome-specific (GhLTP3) promoters. Transgenic tobacco plants were developed via Agrobacterium-mediated transformation. The phenotypic characteristics of the plants were observed after confirming the integration of transgene in plants. It was observed that CpPIP2 expression cassette under 2×35S and GhLTP3 promoter enhanced the numbers of stem and leave trichomes. However, 2×35S::CpPIP2 has a more amplified effect on trichome density and length than GhLTP3::CpPIP2 and other PIP constructs. These findings imply the role of C. procera PIP aquaporins in fiber cell elongation. The PIPs-derived cell expansion mechanism may be exploited through transgenic approaches for improvement of fiber staple length in cotton and boosting of defense against sucking insects by enhancing plant pubescence.
    MeSH term(s) Agrobacterium/genetics ; Aquaporins/genetics ; Aquaporins/metabolism ; Calotropis/genetics ; Calotropis/metabolism ; Cell Membrane/metabolism ; Cloning, Molecular ; DNA, Complementary/metabolism ; Expressed Sequence Tags ; Gene Expression Regulation, Plant ; Gene Library ; Permeability ; Phenotype ; Phylogeny ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Plant Roots/genetics ; Plant Stems/physiology ; Plants, Genetically Modified/genetics ; Promoter Regions, Genetic ; Real-Time Polymerase Chain Reaction ; Nicotiana/genetics ; Nicotiana/metabolism ; Trichomes/physiology ; Water/chemistry
    Chemical Substances Aquaporins ; DNA, Complementary ; Plant Proteins ; Water (059QF0KO0R)
    Language English
    Publishing date 2013-07-03
    Publishing country China
    Document type Journal Article
    ZDB-ID 2247290-3
    ISSN 1862-1783 ; 1673-1581
    ISSN (online) 1862-1783
    ISSN 1673-1581
    DOI 10.1631/jzus.B1200233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Development of a Triple Gene

    Naqvi, Rubab Z / Asif, Muhammad / Saeed, Muhammad / Asad, Shaheen / Khatoon, Asia / Amin, Imran / Mukhtar, Zahid / Bashir, Aftab / Mansoor, Shahid

    Frontiers in plant science

    2017  Volume 8, Page(s) 55

    Abstract: Insect pest complex, cotton leaf curl disease and weeds pose major threat to crop production worldwide, including Pakistan. To address these problems, in the present study a triple gene construct ... ...

    Abstract Insect pest complex, cotton leaf curl disease and weeds pose major threat to crop production worldwide, including Pakistan. To address these problems, in the present study a triple gene construct harboring
    Language English
    Publishing date 2017-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711035-7
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2017.00055
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Transgenic expression of phytase in wheat endosperm increases bioavailability of iron and zinc in grains.

    Abid, Nabeela / Khatoon, Asia / Maqbool, Asma / Irfan, Muhammad / Bashir, Aftab / Asif, Irsa / Shahid, Muhammad / Saeed, Asma / Brinch-Pedersen, Henrik / Malik, Kauser A

    Transgenic research

    2017  Volume 26, Issue 1, Page(s) 109–122

    Abstract: Phytate is a major constituent of wheat seeds and chelates metal ions, thus reducing their bioavailability and so the nutritional value of grains. Transgenic plants expressing heterologous phytase are expected to enhance degradation of phytic acid stored ...

    Abstract Phytate is a major constituent of wheat seeds and chelates metal ions, thus reducing their bioavailability and so the nutritional value of grains. Transgenic plants expressing heterologous phytase are expected to enhance degradation of phytic acid stored in seeds and are proposed to increase the in vitro bioavailability of mineral nutrients. Wheat transgenic plants expressing Aspergillus japonicus phytase gene (phyA) in wheat endosperm were developed till T
    Language English
    Publishing date 2017-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 31620-9
    ISSN 1573-9368 ; 0962-8819
    ISSN (online) 1573-9368
    ISSN 0962-8819
    DOI 10.1007/s11248-016-9983-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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