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  1. Article ; Online: The frequency of asthma and its related factors: results of the enrolment phase of Tabari cohort study.

    Yousefi-Reykandeh, Seyed Sajjad / Moosazadeh, Mahmood / Kheradmand, Motahareh / Hosseini, Amirsaeed / Bagheri-Nesami, Masoumeh

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2024  , Page(s) 1–9

    Abstract: Introduction: A large portion of the world's population has asthma. This study aimed to ascertain asthma prevalence and related factors in the Tabari cohort study (TCS).: Methods: The TCS included 10,255 35-70-year-olds from urban and mountainous ... ...

    Abstract Introduction: A large portion of the world's population has asthma. This study aimed to ascertain asthma prevalence and related factors in the Tabari cohort study (TCS).
    Methods: The TCS included 10,255 35-70-year-olds from urban and mountainous Sari (northern Iran) between June 2015 and November 2017. Education, occupation, domicile, socioeconomic position, history of psychiatric disorders, smoking (including hookah smoking), opium usage, and daily physical activity level were determined.
    Results: The final analysis included 9939 individuals. The asthma rate was 7.4%. Multiple factors increased asthma risk, according to statistical analysis. These factors included being female (OR, 1.337; 95% CI, 1.142-1.565), retired (OR, 1.553; 95% CI, 1.205-2.002), living in the city (OR, 1.268; 95% CI, 1.083-1.484), using opioids (OR, 1.689; 95% CI, 1.299-2.197), having lower socioeconomic status (SES) (OR, 0.723; 95% CI, 0.579-0.903), history of psychiatric disorders (OR, 2.313; 95% CI, 1.826-2.930), and aged 60-70 (OR, 2.325; 95% CI, 1.765-3.064), and BMI above 30 kg/m
    Conclusion: This study has identified that the prevalence of asthma in the Tabari cohort group is high. In addition, it was demonstrated that various factors are related to asthma.
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.1080/02770903.2024.2337850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The association between early menarche and higher-risk cardiometabolic profile: a dose-response analysis of the Tabari cohort at enrollment phase.

    Kheradmand, Motahareh / Hamzehgardeshi, Zeinab / Shahhosseini, Zohreh / Mirjalili, Razie / Moosazadeh, Mahmood

    Frontiers in cardiovascular medicine

    2023  Volume 10, Page(s) 1241179

    Abstract: Objectives: The association between age at menarche and higher-risk cardiometabolic factors is controversial and more strands of evidence are required. Therefore, in this study, we aimed to investigate the effect of early menarche on cardiometabolic ... ...

    Abstract Objectives: The association between age at menarche and higher-risk cardiometabolic factors is controversial and more strands of evidence are required. Therefore, in this study, we aimed to investigate the effect of early menarche on cardiometabolic profile in a large-scale cohort population.
    Study design: Data collected in the enrollment phase of the Tabari cohort study were utilized for the present study. We analyzed data from 6,103 women aged 35-70 years. Logistic regression and dose-response (trend) analyses were used to investigate the effect of early menarche on prevalence of diabetes, dyslipidemia, obesity, high waist circumference (WC), high waist-to-hip ratio (WHR), and high waist-to-height ratio (WHtR).
    Results: The results of the adjusted logistic regression analysis showed that women who experienced early menarche had significantly higher odds of obesity (odds ratio: 1.64, 95% CI: 1.36-1.99,
    Conclusion: The present study showed that early menarche is a strong predictor for later development of obesity and diabetes, and for high WC, WHR, and WHtR. Among all factors examined, age at menarche had the greatest predictive power for WHtR. As an age-dependent anthropometric index for central obesity, WHtR is more suitable as an index for identification of individuals with increased cardiometabolic risk.
    Language English
    Publishing date 2023-09-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1241179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Association between perceived stress and cardio-metabolic risk factors: preliminary results of NURSE (Nursing Unacquainted Related Stress Etiologies) study.

    Kheradmand, Motahareh / Aalaa, Maryam / Salemi, Sedigheh / Moosazadeh, Mahmood / Sanjari, Mahnaz

    Journal of diabetes and metabolic disorders

    2023  Volume 22, Issue 2, Page(s) 1211–1215

    Abstract: Objective: Stress is known as a conventional risk factor of cardiovascular disease. Nurses work in stressful environment and could be one of the target populations to be assessed for cardio metabolic risk factor. This study aimed to identify the ... ...

    Abstract Objective: Stress is known as a conventional risk factor of cardiovascular disease. Nurses work in stressful environment and could be one of the target populations to be assessed for cardio metabolic risk factor. This study aimed to identify the association between perceived stress and cardio-metabolic risk factors in nurses who are prone for various metabolic diseases.
    Method: In this cross-sectional study, nurses from five different educational hospitals of Tehran University of Medical Science attended the study. A self-administered questionnaire as well as Perceived Stress scale were completed. All anthropometric indices and blood pressure were measured. After 10-12 hours of fasting, venous blood samples were taken and level of total cholesterol, triglyceride, high-density and low-density lipoprotein cholesterol, fasting blood sugar and insulin level were determined. Data were analyzed using SPSS version 16 and a p value less than 0.05 was considered statistically significant.
    Results: In total 273 nurses were recruited in this study. The mean age of participants was 35.01 ± 0.399 years old. The mean of perceived stress was 15.55 ± 5.04 with the minimum of 3 and maximum of 30. There was no significant association between perceived stress and cardio-metabolic risk factors. Results showed that there was a negative association between perceived stress and insulin level only in nurses who worked rotationally (β = - 0.195,
    Conclusion: Finding of the current study showed that negative association between perceived stress and insulin level and there is no significant association between stress and cardio-metabolic risk factors in nurses.
    Language English
    Publishing date 2023-06-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2680289-2
    ISSN 2251-6581
    ISSN 2251-6581
    DOI 10.1007/s40200-023-01236-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comparing Vitamin D Level Between Patients with Psoriasis and Healthy Individuals: A Systematic Review and Meta-Analysis.

    Moosazadeh, Mahmood / Damiani, Giovanni / Khademloo, Mohammad / Kheradmand, Motahareh / Nabinezhad-Male, Fatemeh / Hessami, Amirhossein

    Journal of evidence-based integrative medicine

    2023  Volume 28, Page(s) 2515690X231211663

    Abstract: Background: Psoriasis is nowadays regarded as a systemic inflammatory disorder. Among the topicals, vitamin D derivates are often applied on the skin for their anti-inflammatory and immune-modulatory properties. Vitamin D serum levels in psoriasis (PsO) ...

    Abstract Background: Psoriasis is nowadays regarded as a systemic inflammatory disorder. Among the topicals, vitamin D derivates are often applied on the skin for their anti-inflammatory and immune-modulatory properties. Vitamin D serum levels in psoriasis (PsO) patients are still debated and an eventual depletion may offer the rational to integrate anti-psoriatic therapies with oral vitamin D. Then, we aimed to perform a systematic review and meta-analysis on the current evidence towards serum vitamin D level in PsO.
    Methods: We searched in PubMed, Scopus, Web of Sciences, ScienceDirect and Science Information Database (SID) using the terms "Vitamin D" and "Psoriasis" including manuscripts in English, Italian and Persian. Duplications were excluded using EndNote software and records were screened by title, abstract and full-text. Quality assessment of studies was assessed using Newcastle Ottawa Checklist (NOS). Psoriasis odds ratio (OR) and mean serum vitamin D levels were calculated and displayed in Forest-plots. Heterogeneity indexes were evaluated using
    Results: From 3006 records extracted, after removing duplicates and analyzing full texts we finally included 19 manuscripts involving a total of 1387 PsO cases and 6939 controls. PsO patients exhibited a substantial odds ratio (3.07, 95% CI: 1.56-6.04) for lower serum vitamin D levels compared to the control group. Standardized Mean Difference (SMD) of vitamin D in PsO versus controls was -0.92 (-1.33 to -0.51).
    Conclusion: Psoriatic patients displayed higher risk to have a vitamin D deficiency. Interventional studies to verify the preventive value are mandatory.
    MeSH term(s) Humans ; Vitamin D/adverse effects ; Vitamins ; Psoriasis/chemically induced ; Vitamin D Deficiency/chemically induced
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ISSN 2515-690X
    ISSN (online) 2515-690X
    DOI 10.1177/2515690X231211663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Association between gravidity and risk of metabolic syndrome: Results of Tabari cohort study.

    Moosazadeh, Mahmood / Takezaki, Toshiro / Saeedi, Majid / Kheradmand, Motahareh

    Diabetes & metabolic syndrome

    2020  Volume 14, Issue 5, Page(s) 843–847

    Abstract: Background and aims: The purpose of the present study was to investigate the association of gravidity and age at first pregnancy with metabolic syndrome in a large-scale, population-based cohort study in Iran.: Methods: The present secondary analysis ...

    Abstract Background and aims: The purpose of the present study was to investigate the association of gravidity and age at first pregnancy with metabolic syndrome in a large-scale, population-based cohort study in Iran.
    Methods: The present secondary analysis was conducted on a subset of the population (5739 women with at least one pregnancy) enrolled in the Tabari cohort study. Reproductive history was collected using a structured questionnaire. The relationship of gravidity and age at first pregnancy with metabolic syndrome and its components was analyzed using the logistic regression model.
    Results: The results showed that after adjustment for confounding variables, the odds of having metabolic syndrome was not significantly associated with age at first pregnancy (P = 0.269) and gravidity (P = 0.504). However, there was an association between hypertension and age at first pregnancy (OR = 0.32, 95% CI = 0.12-0.82; P = 0.03). Additionally, waist circumference was also associated with gravidity (OR = 2.17, 95% CI = 1.37-3.35).
    Conclusion: As the findings indicated, age at first pregnancy and gravidity were not associated with the odds of having metabolic syndrome. However, a relationship was found between first pregnancy at the age of >35 years and the decreased risk of hypertension. Gravidity was also found to be a dose-dependent risk factor for increased waist circumference.
    Language English
    Publishing date 2020-04-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2020.04.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Sleep profile status based on substance use, lipids and demographic variables in Tabari cohort study.

    Enderami, Athena / Afshari, Mahdi / Kheradmand, Motahareh / Alizadeh-Navaei, Reza / Hosseini, Seyed Hamzeh / Moosazadeh, Mahmood

    Sleep medicine: X

    2022  Volume 4, Page(s) 100048

    Abstract: Background: This study aims to investigate the situation of sleep profile and its related factors in the Tabari Cohort Tabari (TCS) population.: Methods: The information of 10255 of the Tabari cohort population in the enrolment phase was used in this ...

    Abstract Background: This study aims to investigate the situation of sleep profile and its related factors in the Tabari Cohort Tabari (TCS) population.
    Methods: The information of 10255 of the Tabari cohort population in the enrolment phase was used in this study. The sleep profile data was collected and recorded by trained questioners. The sleep duration in day & night, the time interval between going bed and falling asleep, continuous use of sedatives, involuntary nap, limb hypermobility during sleep and shift working were determined for each person. Data analysis was performed by independent T test and Pearson correlation coefficient.
    Results: Mean, standard deviation, median, minimum and maximum of sleep duration in this population were 7.6, 1.6, 7.5, 0.5 and 17 h. Frequency of sleeping less than 6 h, 6-10 h and more than 10 h were 1168(11.4%), 8463(82.5%) and 624(6.1%) respectively. Prevalence of sleeping more than 10 h among men and women were 5% and 6.8% respectively (P < 0.001). Prevalence of sedative routine use among men and women were 4.7% and 9.6% respectively (P < 0.001). There were significant relationships between sleep duration and area residence, age group (P < 0.001), education level (P < 0.001), socioeconomic level (P < 0.001), triglyceride (P = 0.002), HDL-cholesterol (P = 0.013) and Cholesterol total (P = 0.021). There was a negative correlation between age and sleep duration (r = -0.062, P < 0.001).
    Conclusion: The results showed the association of the quality and quantity of sleep with personal, social, environmental and biological factors such as gender, age, economic status, educational status, and lipid profile. Therefore without proper intervention, the incidence of outcomes associated with these risk factors can be predicted in TCS In later years.
    Language English
    Publishing date 2022-05-04
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2590-1427
    ISSN (online) 2590-1427
    DOI 10.1016/j.sleepx.2022.100048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Prevalence of self-reported coronary heart disease and its associated risk factors in Tabari cohort population.

    Ghaemian, Ali / Nabati, Maryam / Saeedi, Majid / Kheradmand, Motahareh / Moosazadeh, Mahmood

    BMC cardiovascular disorders

    2020  Volume 20, Issue 1, Page(s) 238

    Abstract: Background: Prevalence of coronary heart disease (CHD) risk factors are increasing in developing countries. The present study aimed to assess the prevalence of self-reported CHD and evaluate the role of various risk factors on its prevalence in the ... ...

    Abstract Background: Prevalence of coronary heart disease (CHD) risk factors are increasing in developing countries. The present study aimed to assess the prevalence of self-reported CHD and evaluate the role of various risk factors on its prevalence in the Tabari cohort study (TCS) population.
    Methods: The enrollment phase of TCS was performed between June 2015 and November 2017. In the current study, data were derived from information collecting from the enrollment phase of TCS. In the enrollment phase, 10,255 individuals aged 35-70 living in urban and mountainous areas of Sari (northern part of Iran) were entered into the study. Educational level, socioeconomic and marital status, history of smoking, opium and alcohol abuse/addiction, level of daily physical activity, indices of obesity, and traditional risk factors of the participants were determined.
    Results: The prevalence of CHD was measured at 9.2%. Older individuals (P<0.001), people with a body mass index≥30kg/m2 (P<0.001), diabetics (P<0.001), and hypertensive (P<0.001) have been shown to have an increased risk for CHD compared with participants of without CHD. Furthermore, the CHD was more prevalent in individuals with higher waist circumference (P<0.001), higher low-density lipoprotein cholesterol (P<0.001), lower high-density lipoprotein cholesterol (P<0.001), and a higher waist to hip ratio (P<0.001). In addition, individuals with low socioeconomic status, illiterate people, and opium users had a higher prevalence of CHD (P<0.001). The results of the multivariable logistic regression analysis showed that the probability of CHD among individuals who had 8-10 risk factors was estimated at 8.41 (95% confidence interval: 5.75-12.31) times higher than those with less than 3 risk factors.
    Conclusion: According to the results of the present study, it seems that the prevalence of CHD in the Iranian population is relatively high.
    MeSH term(s) Adult ; Aged ; Comorbidity ; Coronary Disease/diagnosis ; Coronary Disease/epidemiology ; Female ; Humans ; Iran/epidemiology ; Life Style ; Male ; Middle Aged ; Prevalence ; Risk Factors ; Self Report ; Social Determinants of Health ; Socioeconomic Factors
    Language English
    Publishing date 2020-05-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-020-01526-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Association between White Blood Cells Count and Diabetes Mellitus in Tabari Cohort Study: A Case-Control Study.

    Kheradmand, Motahareh / Ranjbaran, Hossein / Alizadeh-Navaei, Reza / Yakhkeshi, Reza / Moosazadeh, Mahmood

    International journal of preventive medicine

    2021  Volume 12, Page(s) 121

    Abstract: Background: White Blood Cells (WBC) can be a useful marker to predict diabetes. In this study, we aimed to investigate the association between WBC count with type 2 diabetes in a large-scaled population-based cohort study.: Methods: In the present ... ...

    Abstract Background: White Blood Cells (WBC) can be a useful marker to predict diabetes. In this study, we aimed to investigate the association between WBC count with type 2 diabetes in a large-scaled population-based cohort study.
    Methods: In the present study we used a subset of data collected in enrolment phase of Tabari cohort study. Participants with fasting blood glucose ≥126 or those who report as having diabetes or taking glucose-lowering medications were selected as case group (1765 participants) and control group included participants who did not report as having diabetes (1765 participants) and they randomly selected from the baseline population. Hematology indices were measured for all participants using Celltac Alpha MEK-6510 K. Chi-squared and independent t-test were used to compare categorical and continuous variables, respectively.
    Results: The mean of WBC in diabetic patients and control group was 6.89 ± 1.67 and 6.37 ± 1.49 respectively (
    Conclusions: Results of the present study showed a significant association between WBC count and diabetes. This association remained significant after adjustment for all possible confounders.
    Language English
    Publishing date 2021-09-29
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2574680-7
    ISSN 2008-8213 ; 2008-7802
    ISSN (online) 2008-8213
    ISSN 2008-7802
    DOI 10.4103/ijpvm.IJPVM_336_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Comparing mental health status and COVID-19 event impact between survivors and the general population during the second wave of the pandemic in Iran.

    Hasannezhad Reskati, Maryam / Kheradmand, Motahareh / Moosazadeh, Mahmood / Assadi, Touraj / Shafizad, Misagh / Hedayatizadeh-Omran, Akbar / Hosseini, Seyed Hamzeh / Elyasi, Forouzan

    Nursing open

    2022  Volume 10, Issue 2, Page(s) 738–753

    Abstract: Background and aim: The coronavirus disease 2019 (COVID-19) pandemic has to date overwhelmed the survivors and the general population. The present study aimed to compare the mental health status and the COVID-19 event impact between the survivors and ... ...

    Abstract Background and aim: The coronavirus disease 2019 (COVID-19) pandemic has to date overwhelmed the survivors and the general population. The present study aimed to compare the mental health status and the COVID-19 event impact between the survivors and the general population in Mazandaran Province, Northern Iran.
    Design: A web-based cross-sectional survey was used.
    Methods: This study was performed using convenience sampling.
    Results: In total, 1,766 participants were included in this study. The findings revealed that the posttraumatic stress disorder (PTSD) severity in both outpatient and hospitalized groups was significantly higher than that in the general population. Besides, the levels of anxiety and depression in the group receiving inpatient care and treatment had significantly elevated than those in the general population.
    Conclusion: Given the high prevalence rate of mental disorders, healthcare professionals are recommended to plan for various interventions and support services to boost community mental health status.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; SARS-CoV-2 ; Iran/epidemiology ; Cross-Sectional Studies ; Mental Health ; Health Status ; Survivors
    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2809556-X
    ISSN 2054-1058 ; 2054-1058
    ISSN (online) 2054-1058
    ISSN 2054-1058
    DOI 10.1002/nop2.1341
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  10. Article ; Online: Comparison of EMLA and Diclofenac on Reduction of Pain and Phlebitis Caused by Peripheral IV Catheter: A Randomized-Controlled Trial Study.

    Babaieasl, Faezeh / Yarandi, Hossein N / Saeidzadeh, Seyedehtanaz / Kheradmand, Motahareh

    Home healthcare now

    2019  Volume 37, Issue 1, Page(s) 17–22

    Abstract: Peripheral venous catheters (PVC) are often used to provide hydration, medications, and blood products when the length of therapy is expected to be less than 1 week. Pain and phlebitis are frequent complications of PVC. Diclofenac and EMLA have been used ...

    Abstract Peripheral venous catheters (PVC) are often used to provide hydration, medications, and blood products when the length of therapy is expected to be less than 1 week. Pain and phlebitis are frequent complications of PVC. Diclofenac and EMLA have been used to minimize these adverse effects; however, conflicting results have been reported regarding which has better outcomes. This double-blind, randomized controlled trial was conducted to compare the efficacy of EMLA and Diclofenac (TDP) in attenuating PVC pain and phlebitis. The inpatient setting was chosen because of the higher frequency of PVC insertions, allowing for a sufficient sample size. One hundred fifty-four subjects were randomly assigned to three groups: EMLA patch (n = 61), a TDP patch (n = 50), or a patch with lubricant gel (n = 46) as a placebo. The pain was measured by Visual Analogue Scale (VAS). Phlebitis was examined based on Boxter criteria in intervals of 6, 12, 18, 24, and 48 hours after PVC insertion. The mean score of VAS was 41.86 ± 22.49 for the control, 39.40 ± 21.60 for TDP, and 38.77 ± 23.28 for the EMLA group, with no significant differences in pain severity between the three groups. The rate of phlebitis in the group with EMLA was significantly higher than the other two groups at 6, 12, and 18 hours (p = 0.02, p = 0.003 and p = 0.04, respectively). In all interval times, the rate of phlebitis in the TDP group was significantly lower than the other groups. Compared with men, women experienced higher rate of phlebitis and intensity of PVC pain. EMLA and TDP had similar analgesic effects, but phlebitis was less frequently observed with TDP, suggesting TDP as a potential medication for reducing pain and phlebitis before PVC insertion.
    MeSH term(s) Adult ; Anesthetics, Combined/therapeutic use ; Anesthetics, Local/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Catheterization, Peripheral/adverse effects ; Diclofenac/therapeutic use ; Double-Blind Method ; Female ; Humans ; Lidocaine, Prilocaine Drug Combination/therapeutic use ; Male ; Pain/drug therapy ; Pain/etiology ; Pain Measurement/methods
    Chemical Substances Anesthetics, Combined ; Anesthetics, Local ; Anti-Inflammatory Agents, Non-Steroidal ; Lidocaine, Prilocaine Drug Combination ; Diclofenac (144O8QL0L1)
    Language English
    Publishing date 2019-01-04
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2814267-6
    ISSN 2374-4537 ; 2374-4529
    ISSN (online) 2374-4537
    ISSN 2374-4529
    DOI 10.1097/NHH.0000000000000704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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