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Article ; Online: Development of an Artificial Intelligence-Based Breast Cancer Detection Model by Combining Mammograms and Medical Health Records

Nguyen Thi Hoang Trang / Khuong Quynh Long / Pham Le An / Tran Ngoc Dang

Diagnostics, Vol 13, Iss 346, p

2023 Volume 346

Abstract: Background: Artificial intelligence (AI)-based computational models that analyze breast cancer have been developed for decades. The present study was implemented to investigate the accuracy and efficiency of combined mammography images and clinical ... ...

Abstract	Background: Artificial intelligence (AI)-based computational models that analyze breast cancer have been developed for decades. The present study was implemented to investigate the accuracy and efficiency of combined mammography images and clinical records for breast cancer detection using machine learning and deep learning classifiers. Methods: This study was verified using 731 images from 357 women who underwent at least one mammogram and had clinical records for at least six months before mammography. The model was trained on mammograms and clinical variables to discriminate benign and malignant lesions. Multiple pre-trained deep CNN models to detect cancer in mammograms, including X-ception, VGG16, ResNet-v2, ResNet50, and CNN3 were employed. Machine learning models were constructed using k-nearest neighbor (KNN), support vector machine (SVM), random forest (RF), Artificial Neural Network (ANN), and gradient boosting machine (GBM) in the clinical dataset. Results: The detection performance obtained an accuracy of 84.5% with a specificity of 78.1% at a sensitivity of 89.7% and an AUC of 0.88. When trained on mammography image data alone, the result achieved a slightly lower score than the combined model (accuracy, 72.5% vs. 84.5%, respectively). Conclusions: A breast cancer-detection model combining machine learning and deep learning models was performed in this study with a satisfactory result, and this model has potential clinical applications.
Keywords	breast cancer ; Xception ; Resnet-v2 ; Resnet50 ; VGG16 ; CNN ; Medicine (General) ; R5-920
Subject code	006
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Impact assessment of mobility restriction, testing, and vaccination on the COVID-19 pandemic in India

Shin, Jeonghyun / Khuong, Quynh Long / Abbas, Kaja / Oh, Juhwan

medRxiv

Abstract: Background: Before the availability of vaccines, countries largely relied on mobility restriction and testing to mitigate the COVID-19 pandemic. Our aim is to assess the combined impact of mobility restriction, testing, and vaccination on the COVID-19 ... ...

Abstract	Background: Before the availability of vaccines, countries largely relied on mobility restriction and testing to mitigate the COVID-19 pandemic. Our aim is to assess the combined impact of mobility restriction, testing, and vaccination on the COVID-19 pandemic in India. Methods: We conducted a multiple regression analysis to assess the impact of mobility, testing, and vaccination on COVID-19 incidence between April 28, 2021 to November 24, 2021 using data from Our World in Data and Google Mobility Report. The 7-day moving average was applied to offset the daily fluctuations in the mobility and testing. Each independent variable was lagged to construct a temporal relationship, and waning vaccination efficacy was taken into consideration. We performed additional analysis for three time periods between March 28, 2020 to November 24, 2021 (1st: March 28, 2020 ~ October 7, 2020, 2nd: October 8, 2020 ~ April 27, 2021, 3rd: April 28, 2021 ~ November 24, 2021) to examine potential heterogeneity over time. Results: Mobility (0.041, 95% CI: 0.033 to 0.048), testing (-0.008, 95% CI: -0.015 to -0.001), and vaccination (quadratic term: 0.004, 95% CI: 0.003 to 0.005, linear term: -0.130, 95% CI: -0.161 to -0.099) were all associated with COVID-19 incidence. For vaccination rate, the decrease of number of cases demonstrated a U-shaped curve, while mobility showed a positive association and testing showed an inverse association with COVID-19 incidence. Mobility restriction was effective during all three periods - March 28, 2020 to November 24, 2021 (0.009, 0.048, and 0.026 respectively). Testing was effective during the second and third period - October 8, 2020 to November 24, 2021 (-0.036, and -0.006 respectively). Conclusion: Mobility restriction and testing were effective even in the presence of vaccination. This shows the positive value of mobility restrictions, testing, and vaccination from the health system perspective on COVID-19 prevention and control, especially with continual emergence of variants in India and globally. At the same time, this health system gain must be balanced with the challenges in the delivery of non-COVID health services and broader socio-economic impact in deciding the prolonged continuance of mobility restriction.
Keywords	covid19
Language	English
Publishing date	2022-03-25
Publisher	Cold Spring Harbor Laboratory Press
Document type	Article ; Online
DOI	10.1101/2022.03.24.22272864
Database	COVID19

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Article ; Online: Severe Symptoms of Mental Disorders Among Students Majoring in Foreign Languages in Vietnam

Nguyen Thi Thang / Dao Thi Dieu Linh / Ta Nhat Anh / Nguyen Thị Phuong / Nguyen Duc Giang / Nguyen Xuan Long / Dao Thi Cam Nhung / Khuong Quynh Long

Frontiers in Public Health, Vol

A Cross-Sectional Study

2022 Volume 10

Abstract: Mental health disorders among university students have been a serious issue in many countries and can negatively affect academic performance and all aspects of daily living, relationships, and physical health. In this study, we aim to estimate the ... ...

Abstract	Mental health disorders among university students have been a serious issue in many countries and can negatively affect academic performance and all aspects of daily living, relationships, and physical health. In this study, we aim to estimate the prevalence of severe symptoms of mental disorders and examine associated factors among students majoring in foreign languages in Vietnam. We used the Depression, Anxiety, and Stress Scales (DASS-21) to detect severe symptoms of mental disorders in 1,788 students, including severe symptoms of depression, anxiety, and stress. The Financial-Study-Family-Friend (FSFF) scale was utilized to assess how much students worried about finance, academic, and social support from family and friends. Multiple logistic regressions were carried out to evaluate the relationship between severe symptoms of mental disorders and FSFF factors. The prevalence of severe levels of depression, anxiety, and stress were 21.1, 35.0, and 16.3%, respectively. While varying somewhat due to students' demographic characteristics, all four aspects of the FSFF scale were related to the severe symptoms of mental disorders of students. Concerns about study had the largest effects (ORs ranging from 2.84 to 3.72) while difficulty in finance had the smallest effects (ORs ranging from 1.23 to 1.37) on students' depression, anxiety, and stress. The prevalence of severe symptoms of mental disorders in students was high in our study. Teachers and universities should focus more attention on students' mental health. Social support from family and friends also plays a crucial role in the mental health of students.
Keywords	social factors ; foreign languages ; student ; Vietnam ; symptoms of mental disorders ; Public aspects of medicine ; RA1-1270
Subject code	150
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Describing the pattern of the COVID-19 epidemic in Vietnam.

Hoang, Van Minh / Hoang, Hong Hanh / Khuong, Quynh Long / La, Ngoc Quang / Tran, Thi Tuyet Hanh

Global health action

2020 Volume 13, Issue 1, Page(s) 1776526

Abstract: Given the rapid spread of the COVID-19 pandemic and the huge negative impacts it is causing, researching on COVID-19-related issues is very important for designing proactive and comprehensive public health interventions to fight against the pandemic. We ... ...

Abstract	Given the rapid spread of the COVID-19 pandemic and the huge negative impacts it is causing, researching on COVID-19-related issues is very important for designing proactive and comprehensive public health interventions to fight against the pandemic. We describe the characteristics of COVID-19 patients detected in the two phases of the epidemic in Vietnam. Data used in this paper were mainly obtained from the official database of the Ministry of Health of Vietnam. Descriptive statistics were carried out using Stata 16 software. As of 18 May 2020, the cumulative number of COVID-19 cases detected in Vietnam was 324, 16 cases from 4 cities and provinces in the first phase (during 20 days, 0.8 cases detected per day) and 308 cases from 35 cities, provinces in the second phase (during 76 days, 4.1 cases detected per day). Vietnam has mobilized its entire political system to fight the COVID-19 and achieved some initial successes. We found both similarities and differences between the two phases of the COVID-19 epidemic in Vietnam. We demonstrated that the situation of the COVID-19 epidemic in Vietnam is getting more complicated and unpredictable.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Cities ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Politics ; Public Health ; SARS-CoV-2 ; Vietnam/epidemiology
Keywords	covid19
Language	English
Publishing date	2020-05-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2540569-X
ISSN	1654-9880 ; 1654-9880
ISSN (online)	1654-9880
ISSN	1654-9880
DOI	10.1080/16549716.2020.1776526
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Smoking Cessation, Quit Attempts and Predictive Factors among Vietnamese Adults in 2020.

Luu, Ngoc Minh / Tran, Thi Tuyet Hanh / Luong, Ngoc Khue / Phan, Thi Hai / Phan, Van Can / Khuong, Quynh Long / Nguyen, Thuy Linh / Duong, Tu Anh / Oh, Jin Kyoung / Vu, Thi Hoang Lan / Vu, Van Giap / Hoang, Van Minh

Asian Pacific journal of cancer prevention : APJCP

2023 Volume 24, Issue 5, Page(s) 1701–1710

Abstract: Objective: This study aims to describe the updated smoking cessation and quit attempt rates and associated factors among Vietnamese adults in 2020.: Methods: Data on tobacco use among adults in Vietnam in 2020 was derived from the Provincial Global ... ...

Abstract	Objective: This study aims to describe the updated smoking cessation and quit attempt rates and associated factors among Vietnamese adults in 2020. Methods: Data on tobacco use among adults in Vietnam in 2020 was derived from the Provincial Global Adult Tobacco Survey. The participants in the study were people aged 15 and older. A total of 81,600 people were surveyed across 34 provinces and cities. Multi-level logistic regression was used to examine the associations between individual and province-level factors on smoking cessation and quit attempts. Results: The smoking cessation and quit attempt rates varied significantly across the 34 provinces. The average rates of people who quit smoking and attempted to quit were 6.3% and 37.2%, respectively. The factors associated with smoking cessation were sex, age group, region, education level, occupation, marital status, and perception of the harmful effects of smoking. Attempts to quit were significantly associated with sex, education level, marital status, perception of the harmful effects of smoking, and visiting health facilities in the past 12 months. Conclusions: These results may be useful in formulating future smoking cessation policies and identifying priority target groups for future interventions. However, more longitudinal and follow-up studies are needed to prove a causal relationship between these factors and future smoking cessation behaviors.
MeSH term(s)	Adult ; Humans ; Smoking Cessation/methods ; Smoking ; Vietnam/epidemiology ; Southeast Asian People ; Health Behavior
Language	English
Publishing date	2023-05-01
Publishing country	Thailand
Document type	Journal Article
ZDB-ID	2218955-5
ISSN	2476-762X ; 1513-7368
ISSN (online)	2476-762X
ISSN	1513-7368
DOI	10.31557/APJCP.2023.24.5.1701
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Treatment for COVID-19 patients in Vietnam

Khuong Quynh Long / Hoang Hong Hanh / Tran Thi Tuyet Hanh / La Ngoc Quang / Hoang Van Minh

Asian Pacific Journal of Tropical Medicine, Vol 13, Iss 9, Pp 397-

Analysis of time-to-recovery

2020 Volume 401

Abstract: Objective: To describe the recovery time and related factors among COVID-19 patients in Vietnam. Methods: We used the secondary data obtained from the official database of the Ministry of Health of Vietnam and other public data sources that were ... ...

Abstract	Objective: To describe the recovery time and related factors among COVID-19 patients in Vietnam. Methods: We used the secondary data obtained from the official database of the Ministry of Health of Vietnam and other public data sources that were available by April 9th, 2020. Cox proportional hazards model was carried out to identify factors related to recovery time among COVID-19 patients. Results: By April 9th, 2020, the cumulative number of COVID-19 cases detected in Vietnam was 255, of which 129 (50.6%) patients had fully recovered. The median recovery time of patients was 17 (95% CI=16-19) days. Older patients had a lower likelihood of recovery (HR=0.98, 95% CI=0.97-0.99, P<0.001), whereas patients with a history of international incoming travel had a higher likelihood of recovery (HR=1.57, 95% CI=1.03-2.40, P=0.036). There was no statistically significant difference in the recovery time of patients treated in different hospital settings. Conclusions: More attention is needed for older patients and who did not have international travel history. Patients confirmed with COVID-19 could be treated at local health facilities to avoid unnecessary referrals and burdens to specialized hospitals at the central level.
Keywords	covid-19 ; coronavirus ; recovery ; vietnam ; Arctic medicine. Tropical medicine ; RC955-962 ; covid19
Subject code	616
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evaluation of community-based screening tools for the early screening of osteoporosis in postmenopausal Vietnamese women.

Bui, My Hanh / Dao, Phuoc Thang / Khuong, Quynh Long / Le, Phuong-Anh / Nguyen, Thuy-Trang Thi / Hoang, Gia Du / Le, Tu Hoang / Pham, Hoai Thu / Hoang, Hong-Xuyen Thi / Le, Quang Cuong / Dao, Xuan Thanh

PloS one

2022 Volume 17, Issue 4, Page(s) e0266452

Abstract: Background: Osteoporosis affects people worldwide. However, there are few validated tools for the early screening of osteoporosis in Vietnam. We set out to evaluate the performance of the osteoporosis self-assessment tool for Asians (OSTA) and the ... ...

Abstract	Background: Osteoporosis affects people worldwide. However, there are few validated tools for the early screening of osteoporosis in Vietnam. We set out to evaluate the performance of the osteoporosis self-assessment tool for Asians (OSTA) and the osteoporosis screening tool for Chinese (OSTC) for the early screening of osteoporosis in postmenopausal Vietnamese women. Methods: We analyzed retrospective data from 797 postmenopausal Vietnamese women. The bone mineral density (BMD) in the lumbar vertebrae (L1-L4) and the left and right femoral necks of all participants were measured using dual-energy X-ray absorptiometry (DXA). Osteoporosis was defined as the BMD (T-score) < -2.5. The OSTA and OSTC scores were calculated from the age and weight of participants. Receiver operating characteristic analysis was conducted to compare the performance of the two tools with the BMD measurements by DXA at different anatomical sites. Results: The rates of osteoporosis determined by BMD varied between anatomical sites, and ranged from 43.4% to 54.7% in the lumbar vertebrae and 29.2% and 8.9% in the left and right femoral necks, respectively. For the vertebrae, the area under the curve (AUC) for OSTA ranged from 70.9% to 73.9% and for OSTC ranged from 68.7% to 71.6%. The predictive value of both tools was higher for femoral necks, with the AUC of OSTA for the left and right femoral necks being 80.0% and 85.8%, respectively. The corresponding figures for OSTC were 80.5% and 86.4%, respectively. The highest sensitivity and specificity of OSTA were 74.6% and 81.4%, while these figures for OSTC were 73.9% and 82.6%, respectively. Conclusion: OSTA and OSTC were shown to be useful self-assessment tools for osteoporosis detection in Vietnam postmenopausal women. Further research is encouraged to determine the applicability of tools for other populations and settings.
MeSH term(s)	Absorptiometry, Photon ; Bone Density ; Female ; Humans ; Lumbar Vertebrae/diagnostic imaging ; Mass Screening ; Osteoporosis/diagnostic imaging ; Osteoporosis/epidemiology ; Osteoporosis, Postmenopausal/diagnostic imaging ; Osteoporosis, Postmenopausal/epidemiology ; Postmenopause ; Retrospective Studies ; Risk Assessment ; Sensitivity and Specificity ; Vietnam/epidemiology
Language	English
Publishing date	2022-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0266452
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Describing the pattern of the COVID-19 epidemic in Vietnam

Hoang, Van Minh / Hoang, Hong Hanh / Khuong, Quynh Long / La, Ngoc Quang / Tran, Thi Tuyet Hanh

Global Health Action

2020 Volume 13, Issue 1, Page(s) 1776526

Keywords	Public Health, Environmental and Occupational Health ; Health Policy ; covid19
Language	English
Publisher	Informa UK Limited
Publishing country	uk
Document type	Article ; Online
ZDB-ID	2540569-X
ISSN	1654-9880 ; 1654-9716
ISSN (online)	1654-9880
ISSN	1654-9716
DOI	10.1080/16549716.2020.1776526
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Describing the pattern of the COVID-19 epidemic in Vietnam

Hoang, Van Minh / Hoang, Hong Hanh / Khuong, Quynh Long / La, Ngoc Quang / Tran, Thi Tuyet Hanh

Glob Health Action

Abstract	Given the rapid spread of the COVID-19 pandemic and the huge negative impacts it is causing, researching on COVID-19-related issues is very important for designing proactive and comprehensive public health interventions to fight against the pandemic. We describe the characteristics of COVID-19 patients detected in the two phases of the epidemic in Vietnam. Data used in this paper were mainly obtained from the official database of the Ministry of Health of Vietnam. Descriptive statistics were carried out using Stata 16 software. As of 18 May 2020, the cumulative number of COVID-19 cases detected in Vietnam was 324, 16 cases from 4 cities and provinces in the first phase (during 20 days, 0.8 cases detected per day) and 308 cases from 35 cities, provinces in the second phase (during 76 days, 4.1 cases detected per day). Vietnam has mobilized its entire political system to fight the COVID-19 and achieved some initial successes. We found both similarities and differences between the two phases of the COVID-19 epidemic in Vietnam. We demonstrated that the situation of the COVID-19 epidemic in Vietnam is getting more complicated and unpredictable.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32588779
Database	COVID19

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Article ; Online: Respiratory complications after surgery in Vietnam

Bui My Hanh / Khuong Quynh Long / Le Phuong Anh / Doan Quoc Hung / Duong Tuan Duc / Pham Thanh Viet / Tran Tien Hung / Nguyen Hong Ha / Tran Binh Giang / Duong Duc Hung / Hoang Gia Du / Dao Xuan Thanh / Le Quang Cuong

The Lancet Regional Health. Western Pacific, Vol 10, Iss , Pp 100125- (2021)

National estimates of the economic burden

2021

Abstract: Background: Estimating the cost of postoperative respiratory complications is crucial in developing appropriate strategies to mitigate the global and national economic burden. However, systematic analysis of the economic burden in low- and middle-income ... ...

Abstract	Background: Estimating the cost of postoperative respiratory complications is crucial in developing appropriate strategies to mitigate the global and national economic burden. However, systematic analysis of the economic burden in low- and middle-income countries is lacking. Methods: We used the nationwide database of the Vietnam Social Insurance agency and extracted data from January 2017 to September 2018. The data contain 1 241 893 surgical patients undergoing one of seven types of surgery. Propensity score matching method was used to match cases with and without complications. We used generalized gamma regressions to estimate the direct medical costs; logistic regressions to evaluate the impact of postoperative respiratory complications on re-hospitalization and outpatient visits. Findings: Postoperative respiratory complications increased the odds of re-hospitalization and outpatient visits by 3·49 times (95% CI: 3·35–3·64) and 1·39 times (95% CI: 1·34–1·45) among surgical patients, respectively. The mean incremental cost associated with postoperative respiratory complications occurring within 30 days of the index admission was 1053·3 USD (95% CI: 940·7–1165·8) per procedure, which was equivalent to 41% of the GDP per capita of Vietnam in 2018. We estimated the national annual incremental cost due to respiratory complications occurring within 30 days after surgery was 13·87 million USD. Pneumonia contributed the greatest part of the annual cost burden of postoperative respiratory complications. Interpretation: The economic burden of postoperative respiratory complications is substantial at both individual and national levels. Postoperative respiratory complications also increase the odds of re-hospitalization and outpatient visits and increase the length of hospital stay among surgical patients. Funding: The authors did not receive any funds for conducting this study
Keywords	Postoperative respiratory complications ; Economic burden ; Re-hospitalization ; Outpatient visits ; Vietnam ; Public aspects of medicine ; RA1-1270
Subject code	333
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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