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  1. Article: Erratum to "Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles,

    Ghaffari, Solmaz / Alihosseini, Faezeh / Rezayat Sorkhabadi, Seyed Mahdi / Arbabi Bidgoli, Sepideh / Mousavi, Seyyedeh Elaheh / Haghighat, Setareh / Afshar Nasab, Ahoo / Kianvash, Nooshin

    Advanced pharmaceutical bulletin

    2020  Volume 11, Issue 1, Page(s) 204

    Abstract: This corrects the article DOI: 10.15171/apb.2018.046.]. ...

    Abstract [This corrects the article DOI: 10.15171/apb.2018.046.].
    Language English
    Publishing date 2020-11-07
    Publishing country Iran
    Document type Published Erratum
    ZDB-ID 3018440-X
    ISSN 2251-7308 ; 2228-5881
    ISSN (online) 2251-7308
    ISSN 2228-5881
    DOI 10.34172/apb.2021.088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles,

    Ghaffari, Solmaz / Alihosseini, Faezeh / Rezayat Sorkhabadi, Seyed Mahdi / Arbabi Bidgoli, Sepideh / Mousavi, Seyyedeh Elaheh / Haghighat, Setareh / Afshar Nasab, Ahoo / Kianvash, Nooshin

    Advanced pharmaceutical bulletin

    2018  Volume 8, Issue 3, Page(s) 395–400

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2018-08-29
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 3018440-X
    ISSN 2251-7308 ; 2228-5881
    ISSN (online) 2251-7308
    ISSN 2228-5881
    DOI 10.15171/apb.2018.046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Evaluation of propylene glycol nanoliposomes containing curcumin on burn wound model in rat: biocompatibility, wound healing, and anti-bacterial effects.

    Kianvash, Nooshin / Bahador, Abbas / Pourhajibagher, Maryam / Ghafari, Homanaz / Nikoui, Vahid / Rezayat, Sayed Mehdi / Dehpour, Ahmad Reza / Partoazar, Alireza

    Drug delivery and translational research

    2017  Volume 7, Issue 5, Page(s) 654–663

    Abstract: Curcumin is an effective wound healing agent in burn therapy, but due to its low bioavailability, it is required to be formulated for topical therapy. Liposomal nanocarriers are developed as stable and efficient dermal delivery systems. In this study, we ...

    Abstract Curcumin is an effective wound healing agent in burn therapy, but due to its low bioavailability, it is required to be formulated for topical therapy. Liposomal nanocarriers are developed as stable and efficient dermal delivery systems. In this study, we prepared curcumin-propylene glycol liposomes (Cur-PgL) to treat animals subjected to second degree burns. The characterization tests confirmed the production of monodisperse nanoliposomes of average size of about 145 nm with high entrapment efficiency percentage and a sustained release behavior. TEM analysis of nanocarriers showed no aggregation in long time storage up to 60 days. The biocompatibility of the Cur-PgL formulation was evaluated by ISO standards. We found that Cur-PgL 0.3% was the effective dose in injured rats without any side effects on intact skin. The cytotoxicity of the Cur-PgL 0.3% nanovesicles was also assessed on human dermal fibroblast (HDF) cells. The results showed no detectable cytotoxicity, but considerable cytotoxicity was observed in higher concentration of 1.5 and 3 mg/ml of free and PgL forms of curcumin. Eight days of application of Cur-PgL on burned rats resulted in a significant (P<0.001) recovery of wound repair parameters, and after 18 days, wound contraction occurred significantly (P < 0.001) compared to the other groups. The antibacterial activity of the Cur-PgL formulation was found to be similar to the silver sulfadiazine (SSD) cream 1% regarding the inhibition of the bacterial growth. In conclusion, the low dose of curcumin nanoliposomal formulation efficiently improved injuries and infections of burn wounds and it can be considered in burn therapy.
    MeSH term(s) Administration, Cutaneous ; Administration, Topical ; Animals ; Biological Availability ; Burns/drug therapy ; Cell Line ; Chemistry, Pharmaceutical ; Curcumin/administration & dosage ; Curcumin/chemistry ; Curcumin/pharmacokinetics ; Disease Models, Animal ; Humans ; Liposomes ; Male ; Particle Size ; Propylene Glycols/chemistry ; Rabbits ; Rats ; Wound Healing
    Chemical Substances Liposomes ; Propylene Glycols ; Curcumin (IT942ZTH98)
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2590155-2
    ISSN 2190-3948 ; 2190-393X
    ISSN (online) 2190-3948
    ISSN 2190-393X
    DOI 10.1007/s13346-017-0405-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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