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Artikel ; Online: Intravenous antihypertensive drugs: a double-edged sword?

van Twist, Daan J L / Kietselaer, Bas L J H

2022 Band 41, Heft 2, Seite(n) 220–222

Mesh-Begriff(e)	Humans ; Antihypertensive Agents/adverse effects ; Administration, Intravenous
Chemische Substanzen	Antihypertensive Agents
Sprache	Englisch
Erscheinungsdatum	2022-12-29
Erscheinungsland	England
Dokumenttyp	Editorial ; Comment
ZDB-ID	605532-1
ISSN	1473-5598 ; 0263-6352 ; 0952-1178
ISSN (online)	1473-5598
ISSN	0263-6352 ; 0952-1178
DOI	10.1097/HJH.0000000000003344
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Cocreation to Facilitate Communication and Collaboration Between Multidisciplinary Stakeholders in eHealth Research and Development: Case Study of the CARRIER (Coronary Artery Disease: Risk Estimations and Interventions for Prevention and Early Detection) Consortium.

Latuapon, Elizabeth / Hochstenbach, Laura / Mahr, Dominik / Scheenstra, Bart / Kietselaer, Bas / Spreeuwenberg, Marieke

JMIR human factors

2023 Band 10, Seite(n) e45006

Abstract: Background: Collaboration with diverse stakeholders in eHealth research is fundamental yet complex. Stakeholders from various disciplines do not "speak the same language" and have different levels of power and interest, resulting in contrasting ... ...

Abstract	Background: Collaboration with diverse stakeholders in eHealth research is fundamental yet complex. Stakeholders from various disciplines do not "speak the same language" and have different levels of power and interest, resulting in contrasting objectives, priorities, and expectations. An approach to constructive communication and collaboration is necessary to overcome this complex dynamic. Cocreation, known in the field of eHealth most often to involve end users, may also be suitable for facilitating stakeholder engagement and alignment. Objective: This paper provides insights into the application of cocreation, specifically in the early phases of research that focus on involving and aligning relevant stakeholders from different academic and professional backgrounds. Methods: The case for this study was a group discussion with members of a multidisciplinary consortium that works on developing a personalized eHealth intervention for atherosclerotic cardiovascular disease. Using stakeholder mapping, health and medicine experts, big data scientists, software developers, and an innovation manager (N=8) were invited to participate. The discussion was based on a user scenario and structured according to the Six Thinking Hats of de Bono, representing 6 different types of thinking. The discussion was recorded, transcribed verbatim, and analyzed thematically with the use of ATLAS.ti software. Results: First, informative and intuitive thinking served the preparatory purpose of familiarization with the project details and other participants. Second, positive and critical thinking constituted the body of the discussion and resulted in an in-depth conversation. Third, creative and organizational thinking were action oriented and focused on solutions and planning to safeguard future progress. The participants repeatedly reflected on various intervention-related themes, ranging from intervention content to technical functionalities and from legal requirements to implementation in practice. Moreover, project-related matters were discussed, including stakeholder management and time and budget constraints. Conclusions: This paper demonstrates how cocreation can be of value for multidisciplinary stakeholder engagement and alignment. Based on stakeholder mapping (with whom to discuss), a dream user scenario (what to discuss), and the Six Thinking Hats of de Bono (how to discuss), the participants shared information, discussed differences, searched for solutions, and moved toward a collective approach regarding intervention development. The lessons learned may further improve the understanding of how cocreation can contribute to multidisciplinary collaboration.
Mesh-Begriff(e)	Humans ; Coronary Artery Disease/diagnosis ; Communication ; Interdisciplinary Studies ; Atherosclerosis ; Telemedicine
Sprache	Englisch
Erscheinungsdatum	2023-10-24
Erscheinungsland	Canada
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2292-9495
ISSN (online)	2292-9495
DOI	10.2196/45006
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: BMI is not independently associated with coronary artery calcification in a large single‐center CT cohort

Altintas, Sibel / van Workum, Samanta / Kok, Madeleine / Joosen, Ivo A. P. G. / Versteylen, Mathijs O. / Nelemans, Patricia J. / Wildberger, Joachim E. / Crijns, Harry J. G. M. / Das, Marco / Kietselaer, Bas L. J. H.

Obesity Science & Practice. 2023 Apr., v. 9, no. 2 p.172-178

2023

Abstract: OBJECTIVE: Obesity is associated with cardiovascular disease (CVD) and CVD mortality. However, previous reports showed a paradoxical protective effect in patients with known CVD referred as “obesity paradox”. Therefore, the aim of the present study was ... ...

Abstract	OBJECTIVE: Obesity is associated with cardiovascular disease (CVD) and CVD mortality. However, previous reports showed a paradoxical protective effect in patients with known CVD referred as “obesity paradox”. Therefore, the aim of the present study was to investigate the association of body mass index (BMI) with coronary artery calcification (CAC) in a large outpatient cardiac CT cohort. METHODS: 4.079 patients who underwent cardiac CT between December 2007–May 2014 were analyzed. BMI and clinical risk factors (current smoking, diabetes mellitus type 2, family history, systolic blood pressure, lipid spectrum) were assessed. Missing values were imputed using multiple imputation. CAC extent was categorized as absent (0), mild (>0–100), moderate (>100–400) and severe (>400). RESULTS: Multivariable multinomial logistic regression analysis, including all risk factors as independent variables, showed no association between BMI and CAC. Using absence of calcification as reference category, the odds ratios per unit increase in BMI were 1.01 for mild; 1.02 for moderate; and 1.00 for severe CAC (p‐values ≥0.103). CONCLUSIONS: No statistically significant association was observed between BMI and CAC after adjustment for other risk factors.
Schlagwörter	body mass index ; calcification ; cardiovascular diseases ; coronary vessels ; lipids ; mortality ; obesity ; protective effect ; regression analysis ; risk ; systolic blood pressure
Sprache	Englisch
Erscheinungsverlauf	2023-04
Umfang	p. 172-178.
Erscheinungsort	John Wiley & Sons, Ltd
Dokumenttyp	Artikel ; Online
Anmerkung	JOURNAL ARTICLE
ZDB-ID	2836381-4
ISSN	2055-2238
ISSN	2055-2238
DOI	10.1002/osp4.636
Datenquelle	NAL Katalog (AGRICOLA)

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Artikel ; Online: Reasons and predictors of non-participation in a personalized digital prehabilitation care trial for patients undergoing elective cardiothoracic surgery.

Scheenstra, Bart / Bongers, Bart C / Broeders, Britney / Imkamp, Maike / Van Susante, Lieke / Kietselaer, Bas / Maessen, Jos / Van 't Hof, Arnoud / Sardari Nia, Peyman

Interdisciplinary cardiovascular and thoracic surgery

2023 Band 37, Heft 2

Abstract: Objectives: Prehabilitation through a digital platform could preoperatively improve the physical and mental fitness of patients undergoing cardiothoracic surgery, thereby improving treatment outcomes. This study aimed to describe the reasons and ... ...

Abstract	Objectives: Prehabilitation through a digital platform could preoperatively improve the physical and mental fitness of patients undergoing cardiothoracic surgery, thereby improving treatment outcomes. This study aimed to describe the reasons and predictors of non-participation in a personalized digital prehabilitation care trial (Digital Cardiac Counseling randomized controlled trial) for patients undergoing elective cardiothoracic surgery. Methods: Adult patients scheduled for elective cardiothoracic surgery at the Maastricht University Medical Center+ were approached to participate in a digital prehabilitation care trial, in which patients were informed about their care pathway, monitored for symptom progression and screened for preoperative modifiable risk factors. Baseline characteristics of all eligible patients and reasons of non-participation were registered prospectively. Predictors of non-participation were determined using logistic regression. Results: Between May 2020 and August 2022, 815 patients were eligible for participation; 421 (52%) did not participate in the personalized digital prehabilitation care trial. Reasons for non-participation were 'lack of internet access or insufficient digital skills' (32%), 'wishing no participation' (39%) and 'other reasons' (30%; e.g. vision or hearing impairments, analphabetism, language barriers). Independent predictors of non-participation were age [odds ratio (OR) 1.024 (1.003-1.046), P = 0.024], socioeconomic status [OR 0.267 (0.133-0.536), P < 0.001], current smoker [OR 1.823 (1.124-2.954), P = 0.015] and EuroSCORE II [OR 1.160 (1.042-1.292), P = 0.007]. Conclusions: Half of the eligible patients did not participate in a personalized digital prehabilitation care trial. Non-participants were vulnerable patients, with a more unfavourable risk profile and more modifiable risk factors, who could potentially benefit the most from prehabilitation.
Sprache	Englisch
Erscheinungsdatum	2023-07-24
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	2753-670X
ISSN (online)	2753-670X
DOI	10.1093/icvts/ivad123
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Using clinical prediction models to personalise lifestyle interventions for cardiovascular disease prevention: A systematic literature review.

Bruninx, Anke / Scheenstra, Bart / Dekker, Andre / Maessen, Jos / van 't Hof, Arnoud / Kietselaer, Bas / Bermejo, Iñigo

Preventive medicine reports

2021 Band 25, Seite(n) 101672

Abstract: This study aimed to systematically review the use of clinical prediction models (CPMs) in personalised lifestyle interventions for the prevention of cardiovascular disease. We searched PubMed and PsycInfo for articles describing relevant studies ... ...

Abstract	This study aimed to systematically review the use of clinical prediction models (CPMs) in personalised lifestyle interventions for the prevention of cardiovascular disease. We searched PubMed and PsycInfo for articles describing relevant studies published up to August 1, 2021. These were supplemented with items retrieved via screening references of citations and cited by references. In total, 32 studies were included. Nineteen different CPMs were used to guide the intervention. Most frequently, a version of the Framingham risk score was used. The CPM was used to inform the intensity of the intervention in five studies (16 %), and the intervention's type in 31 studies (97 %). The CPM was supplemented with relative risk estimates for additional risk factors in three studies (9 %), and relative risk estimates for intervention effects in four (13 %). In addition to the estimated risk, the personalisation was determined using criteria based on univariable risk factors in 18 studies (56 %), a lifestyle score in three (9 %), and a physical examination index in one (3 %). We noted insufficient detail in reporting regarding the CPM's use in 20 studies (63 %). In 15 studies (47 %), the primary outcome was a CPM estimate. A statistically significant effect favouring the intervention to the comparator arm was reported in four out of eight analyses (50 %), and a statistically significant improvement compared to baseline in five out of seven analyses (71 %). Due to the design of the included studies, the effect of the use of CPMs is still unclear. Therefore, we see a need for future research.
Sprache	Englisch
Erscheinungsdatum	2021-12-16
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Review
ZDB-ID	2785569-7
ISSN	2211-3355
ISSN	2211-3355
DOI	10.1016/j.pmedr.2021.101672
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Geometric characteristics of bicuspid aortic valves.

Nijs, Jan / Vangelder, Babs / Tanaka, Kaoru / Gelsomino, Sandro / Van Loo, Ines / La Meir, Mark / Maessen, Jos / Kietselaer, Bas L J H

JTCVS techniques

2021 Band 10, Seite(n) 200–215

Abstract: Objective: We studied the coaptation angles α and β in bicuspid aortic valve geometry from computed tomography scan images.: Methods: In 45 patients, we calculated the coaptation angle α (the angle between the nonfused commissures crossing the center ...

Abstract	Objective: We studied the coaptation angles α and β in bicuspid aortic valve geometry from computed tomography scan images. Methods: In 45 patients, we calculated the coaptation angle α (the angle between the nonfused commissures crossing the center of coaptation), angle β (between the nonfused commissures crossing the center of the reference circle), angles γ Results: The coaptation angles α and β were significantly different ( Conclusions: The coaptation angle α is influenced by the length of the raphe, whereas angle β is dependent on the position of the commissures. The position of the raphe can vary and is not always situated in the middle of the free edge. The position of the right/non commissure is variable, whereas the right/left commissure is more fixed.
Sprache	Englisch
Erscheinungsdatum	2021-08-27
Erscheinungsland	United States
Dokumenttyp	Journal Article
ISSN	2666-2507
ISSN (online)	2666-2507
DOI	10.1016/j.xjtc.2021.08.032
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Last-minute cancellation of adult patients scheduled for cardiothoracic surgery in a large Dutch tertiary care centre.

Scheenstra, Bart / Princée, Anouk M A / Imkamp, Maike S V / Kietselaer, Bas / Ganushchak, Yuri M / Van't Hof, Arnoud W J / Maessen, Jos G

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2021 Band 61, Heft 1, Seite(n) 225–232

Abstract: Objectives: Unanticipated cancellation of a surgical procedure is a common problem, causing distress to the patient and increases in healthcare costs. However, limited evidence exists on the effects of last-minute cancellations of cardiothoracic ... ...

Abstract	Objectives: Unanticipated cancellation of a surgical procedure is a common problem, causing distress to the patient and increases in healthcare costs. However, limited evidence exists on the effects of last-minute cancellations of cardiothoracic surgical procedures in particular. The goal of this study was to gain insight into the prevalence of and the reasons for last-minute cancellations and to examine whether cancellation is associated with adverse medical outcomes. Methods: Patients who were scheduled for elective cardiothoracic surgical procedures between January 2017 and June 2019 were evaluated. The reasons for the cancellations were assigned to the categories medically related or process related. We examined the differences in patient characteristics between those designated as no cancellation, medically related cancellations and process-related cancellations. Lastly, we examined the outcomes of patients who experienced a last-minute cancellation of a scheduled operation. Results: A total of 2111 patients were included; of these, 301 (14.3%) had last-minute cancellations. In 78 (26%) cases, the cancellations were attributable to medical reasons (e.g. infection, comorbidities); 215 (71%) of the cancellations were process related (e.g. another patient in more urgent need of surgery, lack of staff). Almost 99% of the operations with a process-related cancellation were rescheduled compared to only 71.8% of the medically related cancelled operations (P < 0.001). Patients with a medically related cancellation had significantly higher 1-year mortality than patients who had no cancellation (unadjusted hazard ratio 2.50; 95% confidence interval, 1.30-4.78; P = 0.006); after adjustment for the EuroSCORE II, this effect remained significant. Conclusions: Last-minute cancellations were commonly seen in our cohort, and the reasons for cancellation were significantly related to adverse medical outcomes.
Mesh-Begriff(e)	Adult ; Appointments and Schedules ; Elective Surgical Procedures ; Humans ; Retrospective Studies ; Tertiary Care Centers
Sprache	Englisch
Erscheinungsdatum	2021-05-21
Erscheinungsland	Germany
Dokumenttyp	Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezab246
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Prevalence of a History of Metabolic or Hypertensive Pregnancy Disorder in Patients With Myocardial Infarction and Non-obstructive Coronary Arteries: An Observational Cohort Study.

Pustjens, Tobias F S / Vranken, Nousjka P A / Jansen, Gwyneth / Winkler, Patty J C / Stein, Mera / Hoebers, Loes / Kietselaer, Bas / Spaanderman, Marc E A / Rasoul, Saman / Ghossein-Doha, Chahinda / van 't Hof, Arnoud W J

Frontiers in cardiovascular medicine

2022 Band 9, Seite(n) 932799

Abstract: Introduction: Myocardial infarction with non-obstructive coronary arteries (MINOCA) predominantly affects younger females. Women with a history of gestational hypertension (GH), preeclampsia (PE), and gestational diabetes mellitus (GDM) are subjected to ...

Abstract	Introduction: Myocardial infarction with non-obstructive coronary arteries (MINOCA) predominantly affects younger females. Women with a history of gestational hypertension (GH), preeclampsia (PE), and gestational diabetes mellitus (GDM) are subjected to an elevated lifetime risk of cardiovascular disease. However, data on the potential association between these obstetric complications and MINOCA is lacking. Therefore, the current study aimed to provide insight in the prevalence of metabolic and hypertensive pregnancy disorders (MHPD) in MINOCA patients and their clinical characteristics. Methods: In this observational cohort study conducted at the Zuyderland Medical Center and Maastricht University Medical Center in the Netherlands, patients were enrolled if they were identified as having MINOCA. Data on individual patient characteristics, laboratory results, electrocardiography as well as (non-)invasive imaging procedures were derived from the electronic health record system. Patients were asked to complete a questionnaire about prior MHPD including GDM, GH, and PE. Patients were grouped into those with MHPD and those with prior uncomplicated normotensive pregnancy (or pregnancies; NP). Results: After excluding patients without 1-year follow-up ( Conclusion: A history of metabolic and hypertensive pregnancy disorders occurred in one-third of female MINOCA patients. In these patients, conventional cardiovascular risk factors were more prevalent compared to NP patients. In most MHPD patients, the specific cause for MINOCA remained unclear.
Sprache	Englisch
Erscheinungsdatum	2022-07-15
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2022.932799
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The Diagnostic and Prognostic Value of Coronary Calcium Scoring in Stable Chest Pain Patients: A Narrative Review.

Koopman, Moniek Y / Willemsen, Robert T A / van der Harst, Pim / van Bruggen, Rykel / Gratama, Jan Willem C / Braam, Richard / van Ooijen, Peter M A / Doggen, Carine J M / Dinant, Geert-Jan / Kietselaer, Bas / Vliegenthart, Rozemarijn

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

2022 Band 194, Heft 3, Seite(n) 257–265

Abstract: Background: Non-contrast computed tomography (CT) scanning allows for reliable coronary calcium score (CCS) calculation at a low radiation dose and has been well established as marker to assess the future risk of coronary artery disease (CAD) events in ... ...

Titelübersetzung	Der diagnostische und prognostische Wert der Koronarkalkmessung bei Patienten mit anhaltenden Brustschmerzen: Ein narrativer Überblick.
Abstract	Background: Non-contrast computed tomography (CT) scanning allows for reliable coronary calcium score (CCS) calculation at a low radiation dose and has been well established as marker to assess the future risk of coronary artery disease (CAD) events in asymptomatic individuals. However, the diagnostic and prognostic value in symptomatic patients remains a matter of debate. This narrative review focuses on the available evidence for CCS in patients with stable chest pain complaints. Method: PubMed, Embase, and Web of Science were searched for literature using search terms related to three overarching categories: CT, symptomatic chest pain patients, and coronary calcium. The search resulted in 42 articles fulfilling the inclusion and exclusion criteria: 27 articles (n = 38 137 patients) focused on diagnostic value and 23 articles (n = 44 683 patients) on prognostic value of CCS. Of these, 10 articles (n = 21 208 patients) focused on both the diagnostic and prognostic value of CCS. Results: Between 22 and 10 037 patients were included in the studies on the diagnostic and prognostic value of CCS, including 43 % and 51 % patients with CCS 0. The most evidence is available for patients with a low and intermediate pre-test probability (PTP) of CAD. Overall, the prevalence of obstructive CAD (OCAD, defined as a luminal stenosis of ≥ 50 % in any of the coronary arteries) as determined with CT coronary angiography in CCS 0 patients, was 4.4 % (n = 703/16 074) with a range of 0-26 % in individual studies. The event rate for major adverse cardiac events (MACE) ranged from 0 % to 2.1 % during a follow-up of 1.6 to 6.8 years, resulting in a high negative predictive value for MACE between 98 % and 100 % in CCS 0 patients. At increasing CCS, the OCAD probability and MACE risk increased. OCAD was present in 58.3 % (n = 617/1058) of CCS > 400 patients with percentages ranging from 20 % to 94 % and MACE occurred in 16.7 % (n = 175/1048) of these patients with percentages ranging from 6.9 % to 50 %. Conclusion: Accumulating evidence shows that OCAD is unlikely and the MACE risk is very low in symptomatic patients with CCS 0, especially in those with low and intermediate PTPs. This suggests a role of CCS as a gatekeeper for additional diagnostic testing. Increasing CCS is related to an increasing probability of OCAD and risk of cardiac events. Additional research is needed to assess the value of CCS in women and patient management in a primary healthcare setting. Key points: · A CCS of zero makes OCAD in patients at low-intermediate PTP unlikely. · A CCS of zero is related to a very low risk of MACE. · Categories of increasing CCS are related to increasing rates of OCAD and MACE. · Future studies should focus on the diagnostic and prognostic value of CCS in symptomatic women and the role in primary care. Citation format: · Koopman MY, Willemsen RT, van der Harst P et al. The Diagnostic and Prognostic Value of Coronary Calcium Scoring in Stable Chest Pain Patients: A Narrative Review. Fortschr Röntgenstr 2022; 194: 257 - 265.
Mesh-Begriff(e)	Calcium ; Chest Pain/diagnostic imaging ; Chest Pain/epidemiology ; Computed Tomography Angiography/methods ; Coronary Angiography/methods ; Coronary Artery Disease/diagnostic imaging ; Female ; Humans ; Predictive Value of Tests ; Prognosis ; Risk Assessment ; Risk Factors
Chemische Substanzen	Calcium (SY7Q814VUP)
Sprache	Englisch
Erscheinungsdatum	2022-01-26
Erscheinungsland	Germany
Dokumenttyp	Journal Article ; Review
ZDB-ID	554830-5
ISSN	1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
ISSN (online)	1438-9010
ISSN	0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
DOI	10.1055/a-1662-5711
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: BMI is not independently associated with coronary artery calcification in a large single-center CT cohort.

Altintas, Sibel / van Workum, Samanta / Kok, Madeleine / Joosen, Ivo A P G / Versteylen, Mathijs O / Nelemans, Patricia J / Wildberger, Joachim E / Crijns, Harry J G M / Das, Marco / Kietselaer, Bas L J H

Obesity science & practice

2022 Band 9, Heft 2, Seite(n) 172–178

Abstract: Objective: Obesity is associated with cardiovascular disease (CVD) and CVD mortality. However, previous reports showed a paradoxical protective effect in patients with known CVD referred as "obesity paradox". Therefore, the aim of the present study was ... ...

Abstract	Objective: Obesity is associated with cardiovascular disease (CVD) and CVD mortality. However, previous reports showed a paradoxical protective effect in patients with known CVD referred as "obesity paradox". Therefore, the aim of the present study was to investigate the association of body mass index (BMI) with coronary artery calcification (CAC) in a large outpatient cardiac CT cohort. Methods: 4.079 patients who underwent cardiac CT between December 2007-May 2014 were analyzed. BMI and clinical risk factors (current smoking, diabetes mellitus type 2, family history, systolic blood pressure, lipid spectrum) were assessed. Missing values were imputed using multiple imputation. CAC extent was categorized as absent (0), mild (>0-100), moderate (>100-400) and severe (>400). Results: Multivariable multinomial logistic regression analysis, including all risk factors as independent variables, showed no association between BMI and CAC. Using absence of calcification as reference category, the odds ratios per unit increase in BMI were 1.01 for mild; 1.02 for moderate; and 1.00 for severe CAC ( Conclusions: No statistically significant association was observed between BMI and CAC after adjustment for other risk factors.
Sprache	Englisch
Erscheinungsdatum	2022-09-07
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2836381-4
ISSN	2055-2238 ; 2055-2238
ISSN (online)	2055-2238
ISSN	2055-2238
DOI	10.1002/osp4.636
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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