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  1. Article ; Online: Developing a Short Assessment of Environmental Health Literacy (SA-EHL).

    Rohlman, Diana / Kile, Molly L / Irvin, Veronica L

    International journal of environmental research and public health

    2022  Volume 19, Issue 4

    Abstract: Environmental health literacy (EHL) is defined as the understanding of how the environment can impact human health, yet there are few tools to quantify EHL. We adapted the Short Assessment of Health Literacy (SAHL) to create the Short Assessment of ... ...

    Abstract Environmental health literacy (EHL) is defined as the understanding of how the environment can impact human health, yet there are few tools to quantify EHL. We adapted the Short Assessment of Health Literacy (SAHL) to create the Short Assessment of Environmental Health Literacy (SA-EHL). Using the Amazon mTurk platform, users (
    MeSH term(s) Adaptation, Physiological ; Environmental Health ; Health Literacy/methods ; Humans ; Reproducibility of Results ; Surveys and Questionnaires ; Translations
    Language English
    Publishing date 2022-02-12
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19042062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Associations between residential proximity to oil and gas extraction and hypertensive conditions during pregnancy: a difference-in-differences analysis in Texas, 1996-2009.

    Willis, Mary D / Hill, Elaine L / Kile, Molly L / Carozza, Susan / Hystad, Perry

    International journal of epidemiology

    2022  Volume 51, Issue 2, Page(s) 525–536

    Abstract: Background: Oil and gas extraction produces air pollutants that are associated with increased risks of hypertension. To date, no study has examined residential proximity to oil and gas extraction and hypertensive conditions during pregnancy. This study ... ...

    Abstract Background: Oil and gas extraction produces air pollutants that are associated with increased risks of hypertension. To date, no study has examined residential proximity to oil and gas extraction and hypertensive conditions during pregnancy. This study quantifies associations between residential proximity to oil and gas development on gestational hypertension and eclampsia.
    Methods: We utilized a population-based retrospective birth cohort in Texas (1996-2009), where mothers reside <10 km from an active or future drilling site (n = 2 845 144.) Using full-address data, we linked each maternal residence at delivery to assign exposure and evaluate this exposure with respect to gestational hypertension and eclampsia. In a difference-in-differences framework, we model the interaction between maternal health before (unexposed) or after (exposed) the start of drilling activity (exposed) and residential proximity near (0-1, >1-2 or >2-3 km) or far (≥3-10 km) from an active or future drilling site.
    Results: Among pregnant women residing 0-1 km from an active oil or gas extraction site, we estimate 5% increased odds of gestational hypertension [95% confidence interval (CI): 1.00, 1.10] and 26% increased odds of eclampsia (95% CI: 1.05, 1.51) in adjusted models. This association dissipates in the 1- to 3-km buffer zones. In restricted models, we find elevated odds ratios among maternal ages ≤35 years at delivery, maternal non-Hispanic White race, ≥30 lbs gained during pregnancy, nulliparous mothers and maternal educational attainment beyond high school.
    Conclusions: Living within 1 km of an oil or gas extraction site during pregnancy is associated with increased odds of hypertensive conditions during pregnancy.
    MeSH term(s) Adult ; Air Pollutants/adverse effects ; Air Pollutants/analysis ; Eclampsia/epidemiology ; Female ; Humans ; Hypertension, Pregnancy-Induced/epidemiology ; Pregnancy ; Retrospective Studies ; Texas/epidemiology
    Chemical Substances Air Pollutants
    Language English
    Publishing date 2022-01-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 187909-1
    ISSN 1464-3685 ; 0300-5771
    ISSN (online) 1464-3685
    ISSN 0300-5771
    DOI 10.1093/ije/dyab246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Urinary polycyclic aromatic hydrocarbons concentrations and hepatitis B antibody serology in the United States (NHANES, 2003–2014)

    Andrews, Faye V / Smit, Ellen / Welch, Barrett M / Ahmed, Sharia M / Kile, Molly L

    Elsevier Inc. Environmental research. 2021 Apr., v. 195

    2021  

    Abstract: Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that are hepatotoxic and immunotoxic. PAH exposure may modulate hepatitis B immunology.We used data from 6 cycles of the National Health and Nutrition Examination Survey (2003–2014) ... ...

    Abstract Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that are hepatotoxic and immunotoxic. PAH exposure may modulate hepatitis B immunology.We used data from 6 cycles of the National Health and Nutrition Examination Survey (2003–2014) to evaluate the associations between urinary PAH metabolites and hepatitis B serology.This analysis included individuals who self-reported receiving ≥3 doses of hepatitis B vaccine and urinary PAH metabolites (i.e. 1-napthol, 2-napthol, 3-fluorene, 2-fluorene, 1-phenanthrene, 1-pyrene, and total PAH [sum of all metabolites]). Separate logistic regression models assessed the association between hepatitis B vaccination status (i.e. individuals who were immune due to vaccination or susceptible) and tertiles of urinary PAH. Models were adjusted for age, gender, race/ethnicity, survey cycle, family income to poverty ratio, BMI, country of birth, serum cotinine, and urinary creatinine.Among participants who reported receiving ≥3 doses of vaccine and had no antibodies indicating a history of hepatitis B infection and/or current hepatitis B infection, dose-response relationships were observed where individuals with the lowest odds of serology indicating a response to the hepatitis B vaccine (i.e., anti-HBs⁺, anti-HBc⁻, and HBsAg⁻) were in the highest tertile of 2-Napthol (adjusted Odds Ratio [aOR]: 0.70, 95% confidence interval [CI]: 0.54, 0.91), 3-Napthol (aOR: 0.68, 95% CI: 0.53, 0.87), 2-Fluorene (aOR: 0.61, 95% CI: 0.54, 0.86), 1-Phenanthrene (aOR: 0.79, 95% CI: 0.65, 0.97), 1-Pyrene (aOR): 0.68, 95% CI: 0.55, 0.83), and total PAH (aOR: 0.73, 95% CI: 0.56, 0.95) had the compared to the lowest tertile.This cross-sectional study supports a hypothesis that PAH exposures experienced by the general US population may modulate hepatitis B vaccine induced immunity. Given the ubiquity of PAH exposures in the US, additional research is warranted to explore the effects of chronic PAH exposures on hepatitis B related humoral immunity.
    Keywords National Health and Nutrition Examination Survey ; antibodies ; blood serum ; confidence interval ; cotinine ; cross-sectional studies ; dose response ; gender ; hepatitis B ; hepatotoxicity ; household income ; humoral immunity ; immunotoxicity ; metabolites ; nationalities and ethnic groups ; odds ratio ; pollution ; poverty ; regression analysis ; research ; serology ; vaccination ; vaccines
    Language English
    Dates of publication 2021-04
    Publishing place Elsevier Inc.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.110801
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: An overview of the Be Well Home Health Navigator Program to reduce contaminants in well water: Design and methods.

    Irvin, Veronica L / Kile, Molly L / Lucas-Woodruff, Christina / Cude, Curtis / Anderson, Lilly / Baylog, Kara / Hovell, Melbourne F / Choun, Soyoung / Kaplan, Robert M

    Contemporary clinical trials

    2024  Volume 140, Page(s) 107497

    Abstract: Background: The Be Well Home Health Navigator Program is a prospective, randomized controlled trial (RCT) implemented to compare a community health navigator program to usual care program to reduce contaminants in drinking water.: Design and setting: ...

    Abstract Background: The Be Well Home Health Navigator Program is a prospective, randomized controlled trial (RCT) implemented to compare a community health navigator program to usual care program to reduce contaminants in drinking water.
    Design and setting: This 4-year two-armed RCT will involve well owners in Oregon that have private drinking water wells that contain arsenic, nitrate, or lead above maximum contaminant levels.
    Intervention: The intervention leverages the trusted relationship between Cooperative Extension Service (CES) Community Educators and rural well owners to educate, assist and motivate to make decisions and set actionable steps to mitigate water contamination. In this study, CES will serve as home health navigators to deliver: 1) individualized feedback, 2) positive reinforcement, 3) teach-back moments, 4) decision-making skills, 5) navigation to resources, 6) self-management, and 7) repeated contact for shaping and maintenance of behaviors. Usual care includes information only with no access to individual meetings with CES.
    Measurable outcomes: Pre-specified primary outcomes include 1) adoption of treatment to reduce exposure to arsenic, nitrate, or lead in water which may include switching to bottled water and 2) engagement with well stewardship behaviors assessed at baseline, and post-6 and 12 months follow-up. Water quality will be measured at baseline and 12-month through household water tests. Secondary outcomes include increased health literacy scores and risk perception assessed at baseline and 6-month surveys.
    Implications: The results will demonstrate the efficacy of a domestic well water safety program to disseminate to other CES organizations.
    Trial registration number: NCT05395663.
    MeSH term(s) Humans ; Arsenic ; Drinking Water ; Nitrates/analysis ; Oregon ; Prospective Studies ; Water Wells
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
    ZDB-ID 2182176-8
    ISSN 1559-2030 ; 1551-7144
    ISSN (online) 1559-2030
    ISSN 1551-7144
    DOI 10.1016/j.cct.2024.107497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Assessing the effectiveness of vehicle emission regulations on improving perinatal health: a population-based accountability study.

    Willis, Mary D / Hill, Elaine L / Kile, Molly L / Carozza, Susan / Hystad, Perry

    International journal of epidemiology

    2021  Volume 49, Issue 6, Page(s) 1781–1791

    Abstract: Background: Since the 1990s, extensive regulations to reduce traffic-related air pollution (TRAP) have been implemented, yet the effectiveness of these regulations has not been assessed with respect to improving infant health. In this study, we evaluate ...

    Abstract Background: Since the 1990s, extensive regulations to reduce traffic-related air pollution (TRAP) have been implemented, yet the effectiveness of these regulations has not been assessed with respect to improving infant health. In this study, we evaluate how infant health risks associated with maternal residences near highways during pregnancy have changed over time.
    Methods: We created a population-based retrospective birth cohort with geocoded residential addresses in Texan metropolitan areas from 1996 through 2009 (n = 2 259 411). We compared term birthweight (37-42 weeks of gestation) among maternal residences <300 m from a highway (high TRAP exposure) (n = 394 346) and 500-3500 m from a highway (comparison group) (n = 1 865 065). We implemented linear regressions to evaluate interactions between high TRAP exposure and birth year, adjusting for demographics, socioeconomic status and neighbourhood context. In addition, we used propensity score matching to further reduce residual confounding.
    Results: From 1996 to 2009, outdoor NO2 decreased by 51.3%, based on regulatory monitoring data in Texas. Among pregnant women who resided in the high TRAP zone during pregnancy, interaction terms between residential location and birth year show that birthweight increased by 1.1 g [95% confidence interval CI): 0.7, 1.5) in unadjusted models and 0.3 g (95% CI: 0.0, 0.6) in matched models. Time-stratified models also show decreasing impacts of living in high TRAP areas on birthweight when comparing infants born in 1996-97 with 2008-09. Sensitivity analyses with alternative exposure and control groups show consistent results.
    Conclusions: Infant health risks associated with maternal residence near highways have reduced over time, paralleling regulatory measures to improve exhaust pipe emissions.
    MeSH term(s) Adult ; Air Pollutants/analysis ; Air Pollution/analysis ; Air Pollution/prevention & control ; Female ; Humans ; Infant ; Pregnancy ; Retrospective Studies ; Social Responsibility ; Texas ; Vehicle Emissions
    Chemical Substances Air Pollutants ; Vehicle Emissions
    Language English
    Publishing date 2021-01-23
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 187909-1
    ISSN 1464-3685 ; 0300-5771
    ISSN (online) 1464-3685
    ISSN 0300-5771
    DOI 10.1093/ije/dyaa137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Corrigendum to: Assessing the effectiveness of vehicle emission regulations on improving perinatal health: a population-based accountability study.

    Willis, Mary D / Hill, Elaine L / Kile, Molly L / Carozza, Susan / Hystad, Perry

    International journal of epidemiology

    2021  Volume 50, Issue 3, Page(s) 1046

    Language English
    Publishing date 2021-06-10
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 187909-1
    ISSN 1464-3685 ; 0300-5771
    ISSN (online) 1464-3685
    ISSN 0300-5771
    DOI 10.1093/ije/dyab076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Associations between Residential Proximity to Oil and Gas Drilling and Term Birth Weight and Small-for-Gestational-Age Infants in Texas: A Difference-in-Differences Analysis.

    Willis, Mary D / Hill, Elaine L / Boslett, Andrew / Kile, Molly L / Carozza, Susan E / Hystad, Perry

    Environmental health perspectives

    2021  Volume 129, Issue 7, Page(s) 77002

    Abstract: Background: Oil and natural gas extraction may produce environmental pollution at levels that affect reproductive health of nearby populations. Available studies have primarily focused on unconventional gas drilling and have not accounted for local ... ...

    Abstract Background: Oil and natural gas extraction may produce environmental pollution at levels that affect reproductive health of nearby populations. Available studies have primarily focused on unconventional gas drilling and have not accounted for local population changes that can coincide with drilling activity.
    Objective: Our study sought to examine associations between residential proximity to oil and gas drilling and adverse term birth outcomes using a difference-in-differences study design.
    Methods: We created a retrospective population-based term birth cohort in Texas between 1996 and 2009 composed of mother-infant dyads (
    Results: The adjusted mean difference in term birth weight for mothers living 0-1 vs.
    Conclusions: Residing near oil and gas drilling sites during pregnancy was associated with a small reduction in term birth weight but not SGA, with some evidence of environmental injustices. Additional work is needed to investigate specific drilling-related exposures that might explain these associations. https://doi.org/10.1289/EHP7678.
    MeSH term(s) Birth Weight ; Environmental Exposure/adverse effects ; Female ; Humans ; Infant ; Infant, Newborn ; Infant, Small for Gestational Age ; Oil and Gas Fields ; Pregnancy ; Pregnancy Outcome/epidemiology ; Retrospective Studies ; Texas/epidemiology
    Language English
    Publishing date 2021-07-21
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP7678
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Urinary polycyclic aromatic hydrocarbons concentrations and hepatitis B antibody serology in the United States (NHANES, 2003-2014).

    Andrews, Faye V / Smit, Ellen / Welch, Barrett M / Ahmed, Sharia M / Kile, Molly L

    Environmental research

    2021  Volume 195, Page(s) 110801

    Abstract: Background: Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that are hepatotoxic and immunotoxic. PAH exposure may modulate hepatitis B immunology.: Objective: We used data from 6 cycles of the National Health and Nutrition ... ...

    Abstract Background: Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants that are hepatotoxic and immunotoxic. PAH exposure may modulate hepatitis B immunology.
    Objective: We used data from 6 cycles of the National Health and Nutrition Examination Survey (2003-2014) to evaluate the associations between urinary PAH metabolites and hepatitis B serology.
    Methods: This analysis included individuals who self-reported receiving ≥3 doses of hepatitis B vaccine and urinary PAH metabolites (i.e. 1-napthol, 2-napthol, 3-fluorene, 2-fluorene, 1-phenanthrene, 1-pyrene, and total PAH [sum of all metabolites]). Separate logistic regression models assessed the association between hepatitis B vaccination status (i.e. individuals who were immune due to vaccination or susceptible) and tertiles of urinary PAH. Models were adjusted for age, gender, race/ethnicity, survey cycle, family income to poverty ratio, BMI, country of birth, serum cotinine, and urinary creatinine.
    Results: Among participants who reported receiving ≥3 doses of vaccine and had no antibodies indicating a history of hepatitis B infection and/or current hepatitis B infection, dose-response relationships were observed where individuals with the lowest odds of serology indicating a response to the hepatitis B vaccine (i.e., anti-HBs
    Conclusion: This cross-sectional study supports a hypothesis that PAH exposures experienced by the general US population may modulate hepatitis B vaccine induced immunity. Given the ubiquity of PAH exposures in the US, additional research is warranted to explore the effects of chronic PAH exposures on hepatitis B related humoral immunity.
    MeSH term(s) Cotinine ; Cross-Sectional Studies ; Hepatitis B/epidemiology ; Humans ; Nutrition Surveys ; Polycyclic Aromatic Hydrocarbons ; United States/epidemiology
    Chemical Substances Polycyclic Aromatic Hydrocarbons ; Cotinine (K5161X06LL)
    Language English
    Publishing date 2021-02-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.110801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Trends in urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) in the non-smoking U.S. population, NHANES 2001-2014.

    Hudson-Hanley, Barbara / Smit, Ellen / Branscum, Adam / Hystad, Perry / Kile, Molly L

    Chemosphere

    2021  Volume 276, Page(s) 130211

    MeSH term(s) Biological Monitoring ; Biomarkers ; Child ; Creatinine ; Diet ; Environmental Monitoring ; Humans ; Nutrition Surveys ; Polycyclic Aromatic Hydrocarbons
    Chemical Substances Biomarkers ; Polycyclic Aromatic Hydrocarbons ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2021-03-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2021.130211
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  10. Article ; Online: Household use of crop residues and fuelwood for cooking and newborn birth size in rural Bangladesh.

    Lee, Mi-Sun / Eum, Ki-Do / Golam, Mostofa / Quamruzzaman, Quazi / Kile, Molly L / Mazumdar, Maitreyi / Christiani, David C

    Occupational and environmental medicine

    2022  Volume 79, Issue 5, Page(s) 333–338

    Abstract: Objectives: We aimed to investigate the association between type of cooking biomass fuels (crop residues vs fuelwood) and newborn birth outcomes in Bangladeshi children.: Methods: In this birth cohort study, pregnant women who were 18 years or older ... ...

    Abstract Objectives: We aimed to investigate the association between type of cooking biomass fuels (crop residues vs fuelwood) and newborn birth outcomes in Bangladeshi children.
    Methods: In this birth cohort study, pregnant women who were 18 years or older with ultrasound confirmed singleton pregnancy of ≤16 weeks of gestation were enrolled from two Bangladesh clinics between January 2008 and June 2011. Exposure to cooking biomass fuels during pregnancy was assessed by an administered questionnaire. The newborn size metrics were measured at the time of delivery. We used multiple linear regression and logistic regression to assess the associations between the type of cooking biomass fuels and birth outcomes after adjusting for covariates.
    Results: A total of 1137 participants were using biomass fuels, including crop residues (30.3%) and fuelwood (69.7%), respectively, for cooking. After adjusting for covariates, the use of crop residues for cooking was associated with a 0.13 SD decrease in birth length (95% CI 0.25 to -0.01), a 0.14 SD decrease in head circumference (95% CI -0.27 to -0.02), and increased risk of low birth weight (LBW, OR 1.52, 95% CI 1.07 to 2.15) compared with the use of fuelwood.
    Conclusion: The use of crop residues for cooking was associated with reduced birth size and increased risk for LBW in Bangladeshi children, implying that the use of crop residues during pregnancy may have a detrimental effect on fetal growth.
    MeSH term(s) Air Pollution, Indoor/analysis ; Bangladesh/epidemiology ; Child ; Cohort Studies ; Cooking ; Female ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Pregnancy
    Language English
    Publishing date 2022-02-28
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1180733-7
    ISSN 1470-7926 ; 1351-0711
    ISSN (online) 1470-7926
    ISSN 1351-0711
    DOI 10.1136/oemed-2021-107908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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