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  1. Article: Emerging Tick-Borne

    Kim, Eun-Ha / Park, Su-Jin

    Microorganisms

    2023  Volume 11, Issue 9

    Abstract: Severe Fever with Thrombocytopenia Syndrome (SFTS), caused ... ...

    Abstract Severe Fever with Thrombocytopenia Syndrome (SFTS), caused by
    Language English
    Publishing date 2023-09-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11092309
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  2. Article ; Online: Associations among workplace incivility, stress coping, and nursing performance in hospital nurses: A path analysis.

    Kim, Eun Ha / Yi, Yeojin

    Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing

    2022  Volume 55, Issue 4, Page(s) 834–842

    Abstract: Purpose: This study aimed to identify the associations among workplace incivility, stress-coping strategy, and nursing performance and confirm how workplace incivility influences nursing performance through the stress-coping strategy.: Design: This ... ...

    Abstract Purpose: This study aimed to identify the associations among workplace incivility, stress-coping strategy, and nursing performance and confirm how workplace incivility influences nursing performance through the stress-coping strategy.
    Design: This is a descriptive, cross-sectional study. Data were collected using a self-reported questionnaire from 245 nurses working at seven hospitals in Korea between December 2019 and January 2020.
    Methods: The associations among the study variables (workplace incivility, stress coping, and nursing performance) were analyzed using path analysis with bootstrapping.
    Results: Supervisors' incivility affected directly and negatively nursing performance although problem-focused coping was mediating between them. By contrast, coworkers' and doctors' incivility was not directly associated with nursing performance through stress-coping strategies.
    Conclusion: Problem-focused coping enhanced nursing performance and was a more effective stress-coping strategy than emotion-focused coping for nurses affected by coworkers' and doctors' incivilities. Supervisors' incivility may be considered a threatening factor to nursing performance even though problem-focused coping partially mediates between supervisors' incivility and nursing performance.
    Clinical relevance: Organizations must prevent all kinds of workplace incivilities from occurring. Nursing managers should periodically monitor the relationship between the supervisors and nurses and be aware of nurses' stress-coping strategies under stressful situations.
    MeSH term(s) Humans ; Incivility ; Cross-Sectional Studies ; Nursing Staff, Hospital ; Adaptation, Psychological ; Surveys and Questionnaires ; Hospitals ; Nurses ; Workplace
    Language English
    Publishing date 2022-12-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2008214-9
    ISSN 1547-5069 ; 1527-6546
    ISSN (online) 1547-5069
    ISSN 1527-6546
    DOI 10.1111/jnu.12864
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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Co-Development of Adolescents' Cooperative and Competitive Attitudes: How it Predicts Mental Health and Academic Achievement.

    Lee, You-Kyung / Kim, Eun Ha / Seo, Eunjin

    Journal of research on adolescence : the official journal of the Society for Research on Adolescence

    2022  Volume 32, Issue 2, Page(s) 681–695

    Abstract: This study used nationally representative longitudinal data in South Korea to examine how joint changes in adolescents' (N = 7324; ... ...

    Abstract This study used nationally representative longitudinal data in South Korea to examine how joint changes in adolescents' (N = 7324; M
    MeSH term(s) Academic Success ; Achievement ; Adolescent ; Attitude ; Child ; Educational Status ; Humans ; Mental Health
    Language English
    Publishing date 2022-05-17
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2017369-6
    ISSN 1532-7795 ; 1050-8392
    ISSN (online) 1532-7795
    ISSN 1050-8392
    DOI 10.1111/jora.12765
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  4. Article ; Online: Fibrillin2 in chloroplast plastoglobules participates in photoprotection and jasmonate-induced senescence.

    Kim, Inyoung / Kim, Eun-Ha / Choi, Yu-Ri / Kim, Hyun Uk

    Plant physiology

    2022  Volume 189, Issue 3, Page(s) 1363–1379

    Abstract: Fibrillins (FBNs) are the major structural proteins of plastoglobules (PGs) in chloroplasts. PGs are associated with defense against abiotic and biotic stresses, as well as lipid storage. Although FBN2 is abundant in PGs, its independent function under ... ...

    Abstract Fibrillins (FBNs) are the major structural proteins of plastoglobules (PGs) in chloroplasts. PGs are associated with defense against abiotic and biotic stresses, as well as lipid storage. Although FBN2 is abundant in PGs, its independent function under abiotic stress has not yet been identified. In this study, the targeting of FBN2 to PGs was clearly demonstrated using an FBN2-YFP fusion protein. FBN2 showed higher expression in green photosynthetic tissues and was upregulated at the transcriptional level under high-light stress. The photosynthetic capacity of fbn2 knockout mutants generated using CRISPR/Cas9 technology decreased rapidly compared with that of wild-type (WT) plants under high-light stress. In addition to the photoprotective function of FBN2, fbn2 mutants had lower levels of plastoquinone-9 and plastochromanol-8. The fbn2 mutants were highly sensitive to methyl jasmonate (MeJA) and exhibited root growth inhibition and a pale-green phenotype due to reduced chlorophyll content. Consistently, upon MeJA treatment, the fbn2 mutants showed faster leaf senescence and more rapid chlorophyll degradation with decreased photosynthetic ability compared with the WT plants. The results of this study suggest that FBN2 is involved in protection against high-light stress and acts as an inhibitor of jasmonate-induced senescence in Arabidopsis (Arabidopsis thaliana).
    MeSH term(s) Arabidopsis/metabolism ; Arabidopsis Proteins/genetics ; Arabidopsis Proteins/metabolism ; Chlorophyll/metabolism ; Chloroplasts/metabolism ; Cyclopentanes ; Fibrillin-2/metabolism ; Gene Expression Regulation, Plant ; Oxylipins ; Plant Leaves/metabolism ; Plant Physiological Phenomena
    Chemical Substances Arabidopsis Proteins ; Cyclopentanes ; Fibrillin-2 ; Oxylipins ; Chlorophyll (1406-65-1) ; jasmonic acid (6RI5N05OWW)
    Language English
    Publishing date 2022-06-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208914-2
    ISSN 1532-2548 ; 0032-0889
    ISSN (online) 1532-2548
    ISSN 0032-0889
    DOI 10.1093/plphys/kiac166
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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: Comparison of outcomes of EUS-guided ablation and surveillance only for pancreatic cystic lesions: a propensity score-matching study (with videos).

    Song, Yun Je / Huh, Gunn / Kim, Eun Ha / Lee, Jung Bok / Park, Do Hyun

    Gastrointestinal endoscopy

    2023  Volume 98, Issue 4, Page(s) 585–596.e3

    Abstract: Background and aims: EUS-guided ethanol ablation is a recently introduced treatment approach for pancreatic cystic lesions (PCLs), including branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs). However, the utility of this procedure is ... ...

    Abstract Background and aims: EUS-guided ethanol ablation is a recently introduced treatment approach for pancreatic cystic lesions (PCLs), including branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs). However, the utility of this procedure is limited because of its relatively low efficacy in treating PCLs.
    Methods: We retrospectively reviewed patients with PCLs, including those with enlarging suspected BD-IPMNs or those with PCLs measuring >3 cm, who were suboptimal candidates for surgery and had been managed using EUS-guided rapid ethanol lavage (EUS-REL; immediate ethanol lavage performed 4 times, 2015-2022) or surveillance only (SO; 2007- 2022). Propensity score matching (PSM) was performed to minimize bias. The primary outcome was the cumulative incidence rate of BD-IPMN progression. Secondary outcomes were the efficacy and safety of EUS-REL, surgical resection rate (SR), overall survival (OS), and disease-specific survival (DSS) in both groups.
    Results: Overall, 169 and 610 patients were included in the EUS-REL and SO groups, respectively. PSM created 159 matched pairs. The radiologic complete resolution rate after EUS-REL was 74%. Procedure-related pancreatitis in the EUS-REL group was 13.0% (n = 22; 19 mild and 3 moderate grade); no severe adverse events were reported. The 10-year cumulative incidence rate of BD-IPMN progression was significantly lower in the EUS-REL group than in the SO group (1.6% vs 21.2%; hazard ratio, 12.35; P = .003). EUS-REL showed a lower tendency of SR compared with that associated with SO. The rates of 10-year OS and 10-year DSS were comparable in both groups.
    Conclusions: EUS-REL was associated with a significantly lower 10-year cumulative incidence rate of BD-IPMN progression and a lower tendency of SR, whereas its 10-year OS and DSS rates were similar to those of SO for PCLs. EUS-REL may be a viable alternative to SO for managing patients with enlarging suspected BD-IPMNs or those with PCLs >3 cm who are suboptimal candidates for surgery.
    MeSH term(s) Humans ; Pancreatic Intraductal Neoplasms ; Propensity Score ; Retrospective Studies ; Pancreatic Neoplasms/surgery ; Ethanol/therapeutic use ; Pancreatic Cyst/surgery
    Chemical Substances Ethanol (3K9958V90M)
    Language English
    Publishing date 2023-05-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2023.05.049
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 283: Show issues Location:
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    Zs.MO 519: Show issues

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  6. Article: Impact of 5-Year Endoscopic Surveillance Intervals with Biopsy following Endoscopic Papillectomy for Ampullary Adenoma.

    So, Hoonsub / Ko, Sung Woo / Shin, Seung Hwan / Kim, Eun Ha / Park, Do Hyun

    Journal of personalized medicine

    2022  Volume 12, Issue 1

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-01-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm12010051
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  7. Article ; Online: Chloroplast-localized PITP7 is essential for plant growth and photosynthetic function in Arabidopsis.

    Kim, Eun-Ha / Poudyal, Roshan Sharma / Lee, Kyeong-Ryeol / Yu, Hami / Gi, Eunji / Kim, Hyun Uk

    Physiologia plantarum

    2022  Volume 174, Issue 4, Page(s) e13760

    Abstract: Recent studies of chloroplast-localized Sec14-like protein (CPSFL1, also known as phosphatidylinositol transfer protein 7, PITP7) showed that CPSFL1 is necessary for photoautotropic growth and chloroplast vesicle formation in Arabidopsis (Arabidopsis ... ...

    Abstract Recent studies of chloroplast-localized Sec14-like protein (CPSFL1, also known as phosphatidylinositol transfer protein 7, PITP7) showed that CPSFL1 is necessary for photoautotropic growth and chloroplast vesicle formation in Arabidopsis (Arabidopsis thaliana). Here, we investigated the functional roles of CPSFL1/PITP7 using two A. thaliana mutants carrying a putative null allele (pitp7-1) and a weak allele (pitp7-2), respectively. PITP7 transcripts were undetectable in pitp7-1 and less abundant in pitp7-2 than in the wild-type (WT). The severity of mutant phenotypes, such as plant developmental abnormalities, levels of plastoquinone-9 (PQ-9) and chlorophylls, photosynthetic protein complexes, and photosynthetic performance, were well related to PITP7 transcript levels. The pitp7-1 mutation was seedling lethal and was associated with significantly lower levels of PQ-9 and major photosynthetic proteins. pitp7-2 plants showed greater susceptibility to high-intensity light stress than the WT, attributable to defects in nonphotochemical quenching and photosynthetic electron transport. PITP7 is specifically bound to phosphatidylinositol phosphates (PIPs) in lipid-binding assays in vitro, and the point mutations R82, H125, E162, or K233 reduced the binding affinity of PITP7 to PIPs. Further, constitutive expression of PITP7
    MeSH term(s) Arabidopsis/metabolism ; Arabidopsis Proteins/metabolism ; Chloroplasts/metabolism ; Mutation ; Photosynthesis/genetics ; Plant Development ; Plastoquinone/metabolism
    Chemical Substances Arabidopsis Proteins ; Plastoquinone (OAC30J69CN)
    Language English
    Publishing date 2022-08-24
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 2020837-6
    ISSN 1399-3054 ; 0031-9317
    ISSN (online) 1399-3054
    ISSN 0031-9317
    DOI 10.1111/ppl.13760
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  8. Article: Approach strategies and application of metabolomics to biotechnology in plants.

    Oh, Seon-Woo / Imran, Muhammad / Kim, Eun-Ha / Park, Soo-Yun / Lee, Sang-Gu / Park, Hyoun-Min / Jung, Jung-Won / Ryu, Tae-Hun

    Frontiers in plant science

    2023  Volume 14, Page(s) 1192235

    Abstract: Metabolomics refers to the technology for the comprehensive analysis of metabolites and low-molecular-weight compounds in a biological system, such as cells or tissues. Metabolites play an important role in biological phenomena through their direct ... ...

    Abstract Metabolomics refers to the technology for the comprehensive analysis of metabolites and low-molecular-weight compounds in a biological system, such as cells or tissues. Metabolites play an important role in biological phenomena through their direct involvement in the regulation of physiological mechanisms, such as maintaining cell homeostasis or signal transmission through protein-protein interactions. The current review aims provide a framework for how the integrated analysis of metabolites, their functional actions and inherent biological information can be used to understand biological phenomena related to the regulation of metabolites and how this information can be applied to safety assessments of crops created using biotechnology. Advancement in technology and analytical instrumentation have led new ways to examine the convergence between biology and chemistry, which has yielded a deeper understanding of complex biological phenomena. Metabolomics can be utilized and applied to safety assessments of biotechnology products through a systematic approach using metabolite-level data processing algorithms, statistical techniques, and database development. The integration of metabolomics data with sequencing data is a key step towards improving additional phenotypical evidence to elucidate the degree of environmental affects for variants found in genome associated with metabolic processes. Moreover, information analysis technology such as big data, machine learning, and IT investment must be introduced to establish a system for data extraction, selection, and metabolomic data analysis for the interpretation of biological implications of biotechnology innovations. This review outlines the integrity of metabolomics assessments in determining the consequences of genetic engineering and biotechnology in plants.
    Language English
    Publishing date 2023-08-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2023.1192235
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  9. Article ; Online: The meaning of "comfort" to elderly individuals living in long-term care hospitals.

    Kim, Eun-Ha / Kim, Kye-Ha

    Applied nursing research : ANR

    2017  Volume 35, Page(s) 59–63

    MeSH term(s) Aged ; Aged, 80 and over ; Female ; Guidelines as Topic ; Humans ; Long-Term Care/psychology ; Male ; Patient Comfort/standards ; Quality of Health Care/standards ; Quality of Life/psychology
    Language English
    Publishing date 2017-02-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1027369-4
    ISSN 1532-8201 ; 0897-1897
    ISSN (online) 1532-8201
    ISSN 0897-1897
    DOI 10.1016/j.apnr.2017.02.001
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2884: Show issues Location:
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  10. Article: Chloroplast‐localized PITP7 is essential for plant growth and photosynthetic function in Arabidopsis

    Kim, Eun‐Ha / Poudyal, Roshan Sharma / Lee, Kyeong‐Ryeol / Yu, Hami / Gi, Eunji / Kim, Hyun Uk

    Physiologia plantarum. 2022 July, v. 174, no. 4

    2022  

    Abstract: Recent studies of chloroplast‐localized Sec14‐like protein (CPSFL1, also known as phosphatidylinositol transfer protein 7, PITP7) showed that CPSFL1 is necessary for photoautotropic growth and chloroplast vesicle formation in Arabidopsis (Arabidopsis ... ...

    Abstract Recent studies of chloroplast‐localized Sec14‐like protein (CPSFL1, also known as phosphatidylinositol transfer protein 7, PITP7) showed that CPSFL1 is necessary for photoautotropic growth and chloroplast vesicle formation in Arabidopsis (Arabidopsis thaliana). Here, we investigated the functional roles of CPSFL1/PITP7 using two A. thaliana mutants carrying a putative null allele (pitp7‐1) and a weak allele (pitp7‐2), respectively. PITP7 transcripts were undetectable in pitp7‐1 and less abundant in pitp7‐2 than in the wild‐type (WT). The severity of mutant phenotypes, such as plant developmental abnormalities, levels of plastoquinone‐9 (PQ‐9) and chlorophylls, photosynthetic protein complexes, and photosynthetic performance, were well related to PITP7 transcript levels. The pitp7‐1 mutation was seedling lethal and was associated with significantly lower levels of PQ‐9 and major photosynthetic proteins. pitp7‐2 plants showed greater susceptibility to high‐intensity light stress than the WT, attributable to defects in nonphotochemical quenching and photosynthetic electron transport. PITP7 is specifically bound to phosphatidylinositol phosphates (PIPs) in lipid‐binding assays in vitro, and the point mutations R82, H125, E162, or K233 reduced the binding affinity of PITP7 to PIPs. Further, constitutive expression of PITP7ᴴ¹²⁵Q or PITP7ᴱ¹⁶²ᴷ in pitp7‐1 homozygous plants restored autotrophic growth in soil but without fully complementing the mutant phenotypes. Consistent with a previous study, our results demonstrate that PITP7 is essential for plant development, particularly the accumulation of PQ‐9 and photosynthetic complexes. We propose a possible role for PITP7 in membrane trafficking of hydrophobic ligands such as PQ‐9 and carotenoids through chloroplast vesicle formation or direct binding involving PIPs.
    Keywords Arabidopsis thaliana ; carotenoids ; chloroplasts ; gene expression ; homozygosity ; hydrophobicity ; ligands ; mutants ; mutation ; null alleles ; photosynthetic electron transport ; plant development ; plant growth ; seedlings ; soil
    Language English
    Dates of publication 2022-07
    Publishing place Blackwell Publishing Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2020837-6
    ISSN 1399-3054 ; 0031-9317
    ISSN (online) 1399-3054
    ISSN 0031-9317
    DOI 10.1111/ppl.13760
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