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  1. Book ; Thesis: Die Bedeutung des Isoenzyms der sauren Phosphatase TRAcP 5b bei Knochenmetastasierung am Beispiel von Prostataerkrankungen

    Kim, Hyun-Ji Antonia

    2015  

    Author's details vorgelegt von Hyun-Ji Antonia Kim
    Language German
    Size V, 101 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2015
    HBZ-ID HT018855500
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: A comparative study of the psychological impacts of tasks related and unrelated to COVID-19 on nurses: a cross-sectional study.

    Kim, Hyun Ji / Lee, Geon Ho

    Journal of Yeungnam medical science

    2021  Volume 39, Issue 3, Page(s) 216–222

    Abstract: Backgruound: This study assessed the psychological impact of the outbreak of coronavirus disease 2019 (COVID-19) on university hospital nurses. It provides an assessment of mental health issues, including depression, anxiety, distress, and burnout of ... ...

    Abstract Backgruound: This study assessed the psychological impact of the outbreak of coronavirus disease 2019 (COVID-19) on university hospital nurses. It provides an assessment of mental health issues, including depression, anxiety, distress, and burnout of nurses dealing directly and indirectly with COVID-19.
    Methods: In a web-based, cross-sectional study, 111 nurses from Daegu Catholic University Hospital in Korea were enrolled from August 4 to August 9, 2020. Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Impact of Event Scale-Revised, and Maslach Burnout Inventory were used to assess the psychological symptoms of depression, anxiety, psychological distress, and burnout among the study participants.
    Results: Of 111 nurses, 35 (31.5%), nine (8.1%), 26 (23.4%), and 49 (44.1%) experienced depression, anxiety, distress, and burnout, respectively. Nurses who performed COVID-19-related tasks were more likely to have moderate depression (related vs. unrelated, 52.0% vs. 25.6%; p=0.037). There were no differences in anxiety, distress, and burnout between nurses with and without COVID-19-related tasks. More than 50% of the participants showed receptive and positive attitudes toward caring for COVID-19 patients.
    Conclusion: Nurses who performed COVID-19-related tasks had a higher risk of depression. There were no significant differences in anxiety, distress, and burnout between the two groups. Since nurses who perform COVID-19-related tasks are more prone to psychological distress, continued psychiatric interventions are required for infectious disease outbreaks with a high mortality rate for healthcare workers who are emotionally vulnerable.
    Language English
    Publishing date 2021-11-03
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2799-8010
    ISSN (online) 2799-8010
    DOI 10.12701/yujm.2021.01361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Gelatin/agar-based color-indicator film integrated with Clitoria ternatea flower anthocyanin and zinc oxide nanoparticles for monitoring freshness of shrimp

    Kim, Hyun-Ji / Roy, Swarup / Rhim, Jong-Whan

    Food hydrocolloids. 2022 Mar., v. 124

    2022  

    Abstract: Gelatin/agar-based smart and functional freshness indicator films were fabricated using blue anthocyanin and zinc oxide nanoparticles (ZnO). The anthocyanin was extracted from butterfly pea (Clitoria ternatea) flower, and ZnO was synthesized using a ... ...

    Abstract Gelatin/agar-based smart and functional freshness indicator films were fabricated using blue anthocyanin and zinc oxide nanoparticles (ZnO). The anthocyanin was extracted from butterfly pea (Clitoria ternatea) flower, and ZnO was synthesized using a simple hydrothermal method. The butterfly pea anthocyanin (BA) and ZnO were evenly dispersed in the polymer matrix to form a compatible film with the gelatin/agar polymer. The addition of BA and ZnO significantly increased the UV blocking properties and surface hydrophobicity without significant changes in the film's mechanical, thermal stability, and water vapor barrier properties. The BA and BA-added films showed excellent pH-responsive color-change properties as well as good color stability and reversibility. In addition, the composite film showed strong antioxidant and strong bactericidal properties, and the antioxidant function was mainly attributed to the BA, and the antibacterial function was attributed to ZnO. The functional and color indicator film was tested to monitor the freshness of shrimp. It showed distinctive color changes during storage, indicating the degradation of the quality of shrimp accompanied by the total volatile basic nitrogen (TVB-N).
    Keywords Clitoria ternatea ; agar ; anthocyanins ; antioxidant activity ; antioxidants ; color ; composite films ; flowers ; freshness ; gelatin ; hot water treatment ; hydrocolloids ; hydrophobicity ; polymers ; shrimp ; thermal stability ; total volatile basic nitrogen ; water vapor ; zinc oxide
    Language English
    Dates of publication 2022-03
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 742742-6
    ISSN 1873-7137 ; 0268-005X
    ISSN (online) 1873-7137
    ISSN 0268-005X
    DOI 10.1016/j.foodhyd.2021.107294
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Effect of sulfur nanoparticles on properties of alginate-based films for active food packaging applications

    Priyadarshi, Ruchir / Kim, Hyun-Ji / Rhim, Jong-Whan

    Food hydrocolloids. 2021 Jan., v. 110

    2021  

    Abstract: Sulfur nanoparticles (SNPs) were prepared and embedded in calcium cross-linked alginate films in varying concentration, and their effect on the functional properties of the films were studied. The FE-SEM image showed uniform dispersion of up to 2 wt% of ... ...

    Abstract Sulfur nanoparticles (SNPs) were prepared and embedded in calcium cross-linked alginate films in varying concentration, and their effect on the functional properties of the films were studied. The FE-SEM image showed uniform dispersion of up to 2 wt% of SNPs, above which aggregation was observed. The addition of 2 wt% of SNPs showed the best results of the tensile and water vapor barrier properties, with an increase in 12% and 41%, respectively. The surface color of the films changed significantly by the addition of SNPs with a decrease in transparency. However, the UV barrier properties showed a considerable increase of 99%. In addition, the incorporation of SNPs increased the hydrophobicity of the film, which was evident by the increased water contact angle and decreased moisture content of the film, as indicated by the thermal analysis results. The antimicrobial activity of alginate/SNPs composite film was tested against foodborne pathogenic bacteria, E. coli and L. monocytogenes. The nanocomposite film did not completely destroy E. coli but showed a bacteriostatic activity to reduce the 60% of bacterial colonies. However, the activity against L. monocytogenes was found to be highly bactericidal at the highest nanoparticle concentration, where a 100% bacterial elimination was observed after 12 h of exposure. Thus, the alginate/SNPs composite film can be used for the packaging of frozen foods with high moisture content that are susceptible to Listeria monocytogenes contamination, such as meat products.
    Keywords Escherichia coli ; Listeria monocytogenes ; alginates ; antibacterial properties ; calcium ; color ; composite films ; contact angle ; crosslinking ; hydrocolloids ; hydrophobicity ; meat ; nanocomposites ; sulfur ; thermal analysis ; water content ; water vapor
    Language English
    Dates of publication 2021-01
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 742742-6
    ISSN 1873-7137 ; 0268-005X
    ISSN (online) 1873-7137
    ISSN 0268-005X
    DOI 10.1016/j.foodhyd.2020.106155
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Effect of blended colorants of anthocyanin and shikonin on carboxymethyl cellulose/agar-based smart packaging film.

    Roy, Swarup / Kim, Hyun-Ji / Rhim, Jong-Whan

    International journal of biological macromolecules

    2021  Volume 183, Page(s) 305–315

    Abstract: Natural colorants (anthocyanin and shikonin) were blended in different ratios (3:1 and 1:3) and used for the preparation of carboxymethyl cellulose (CMC)/agar-based functional halochromic films. The colorants were compatible with the polymer matrix and ... ...

    Abstract Natural colorants (anthocyanin and shikonin) were blended in different ratios (3:1 and 1:3) and used for the preparation of carboxymethyl cellulose (CMC)/agar-based functional halochromic films. The colorants were compatible with the polymer matrix and evenly spread over the polymer matrix. The addition of colorants slightly improved the mechanical strength and significantly improved the water vapor barrier properties of CMC/agar-based films without altering the thermal stability. The color indicator film exhibited excellent UV- barrier properties without substantially reducing the transparency. It also showed distinct pH-responsive color-changing properties in the pH range of 2-12, showing excellent acid and base gas sensing properties. The shikonin-added film showed potent antimicrobial activity against food-borne pathogenic bacteria, and the color indicator films exhibited intense antioxidant activities. The CMC/agar-based color indicator films with improved physical and functional properties are likely to be used in active and intelligent food packaging applications.
    MeSH term(s) Agar/chemistry ; Anthocyanins/chemistry ; Anti-Infective Agents/chemistry ; Carboxymethylcellulose Sodium/chemistry ; Naphthoquinones/chemistry
    Chemical Substances Anthocyanins ; Anti-Infective Agents ; Naphthoquinones ; shikonin (3IK6592UBW) ; Agar (9002-18-0) ; Carboxymethylcellulose Sodium (K679OBS311)
    Language English
    Publishing date 2021-04-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2021.04.162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Relationship between Dietary Na/K Ratio and Bone Mineral Density in Korean Middle-Aged Women.

    Choi, Seong Su / Kim, Yun-A / Kim, Hyun Ji / Cho, Yoon Jeong / Lee, Geon Ho

    Korean journal of family medicine

    2023  Volume 44, Issue 1, Page(s) 21–27

    Abstract: Background: Dietary Na+ or Na+/K+ ratio has been reported to be associated with bone mineral density (BMD). However, this remains unclear, and only a few studies have been reported on the Korean population. Therefore, this study aimed to determine the ... ...

    Abstract Background: Dietary Na+ or Na+/K+ ratio has been reported to be associated with bone mineral density (BMD). However, this remains unclear, and only a few studies have been reported on the Korean population. Therefore, this study aimed to determine the association between dietary Na+, K+, and Na+/K+ ratios and BMD in middle-aged Korean women.
    Methods: This study used data from the Korea National Health and Nutrition Examination Survey 2008-2011. A total of 3,690 women aged >50 years were included. Study participants were classified into quartiles (lowest quartile Q1-highest quartile Q4) according to dietary Na+, K+, and Na+/K+ ratio, and we examined the association of these parameters with BMD. Total femur and lumbar spine BMD were measured using dual-energy X-ray absorptiometry. Multiple linear regression analyses were performed using IBM SPSS ver. 19.0.
    Results: The mean age was 62 years, and a significant negative trend in the β-coefficient regarding dietary Na+ was only observed in the total femur BMD. However, the total femur and lumbar spine BMD decreased from Q1 to Q4 regarding the dietary Na+/K+ ratio (P-value for trend: 0.044 for total femur BMD and 0.002 for lumbar spine BMD).
    Conclusion: A significant negative trend in the β-coefficient for both total femur and lumbar spine BMD was observed regarding the Na+/K+ ratio. Therefore, based on the results of this study, a higher dietary Na+/K+ ratio may be associated with a lower BMD.
    Language English
    Publishing date 2023-01-19
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2674300-0
    ISSN 2092-6715 ; 2005-6443
    ISSN (online) 2092-6715
    ISSN 2005-6443
    DOI 10.4082/kjfm.21.0208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Identification of Ureidocoumarin-Based Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors via Drug Repurposing Approach, Biological Evaluation, and In Silico Studies.

    El-Damasy, Ashraf K / Kim, Hyun Ji / Al-Karmalawy, Ahmed A / Alnajjar, Radwan / Khalifa, Mohamed M / Bang, Eun-Kyoung / Keum, Gyochang

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 4

    Abstract: Discoidin domain receptor 1 (DDR1) kinase has emerged as a promising target for cancer therapy, and selective DDR1 inhibitors have shown promise as effective therapeutic candidates. Herein, we have identified the first coumarin-based selective DDR1 ... ...

    Abstract Discoidin domain receptor 1 (DDR1) kinase has emerged as a promising target for cancer therapy, and selective DDR1 inhibitors have shown promise as effective therapeutic candidates. Herein, we have identified the first coumarin-based selective DDR1 inhibitors via repurposing of a recent series of carbonic anhydrase inhibitors. Among these, ureidocoumarins
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17040427
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Gelatin/agar-based color-indicator film integrated with Clitoria tematea flower anthocyanin and zinc oxide nanoparticles for monitoring freshness of shrimp

    Kim, Hyun-Ji / Roy, Swarup / Rhim, Jong-Whan

    Food hydrocolloids

    2022  Volume 124, Issue Part A, Page(s) 107294

    Language English
    Document type Article
    ZDB-ID 742742-6
    ISSN 0268-005X
    Database Current Contents Nutrition, Environment, Agriculture

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  9. Article: Synergistic effect of UV-C LED irradiation and PLA/PBAT-based antimicrobial packaging film on fresh-cut vegetables

    Kim, Hyun-Ji / Lee, Chae-Lim / Yoon, Ki-Sun / Rhim, Jong-Whan

    Food control. 2022 Aug., v. 138

    2022  

    Abstract: The combined use of ultraviolet-C light-emitting diodes (UV–C LED) irradiation and antimicrobial packaging film was used to secure the safety of fresh-cut vegetables. The antimicrobial packaging film was prepared by adding grapefruit seed extract (GSE) ... ...

    Abstract The combined use of ultraviolet-C light-emitting diodes (UV–C LED) irradiation and antimicrobial packaging film was used to secure the safety of fresh-cut vegetables. The antimicrobial packaging film was prepared by adding grapefruit seed extract (GSE) and zinc oxide nanoparticles (ZnO) to a blend film of poly(lactide) (PLA) and poly(butylene adipate-co-terephthalate) (PBAT). The GSE and ZnO added film (PLA/PBAT/GSE/ZnO film) showed moderate antioxidant activity of about 36.3% and 21.9% in the ABTS and DPPH methods, respectively, and exhibited strong antibacterial activity against Enterohemorrhagic Escherichia coli (EHEC) and Staphylococcus aureus. The UV-C LED treatment reduced EHEC by 0.47, 0.55, and 0.61 Log CFU/g and S. aureus by 0.46, 0.39, and 0.33 Log CFU/g of fresh-cut onion, cabbage, and carrot, respectively. The combined UV-C LED irradiation and antimicrobial packaging showed a significant synergistic effect in reducing the bacteria during storage. After 7 days of storage at 10 °C, it showed 2.02, 2.82, and 2.06 log CFU/g lower E. coli, and 1.59, 1.77, and 1.47 log CFU/g lower S. aureus in onion, cabbage, and carrot, respectively, than the control group. The combined use of UV-C LED and antimicrobial packaging has a high potential to extend the shelf life of fresh-cut vegetables without heat treatment or the addition of chemical preservatives.
    Keywords Staphylococcus aureus ; antibacterial properties ; antioxidant activity ; cabbage ; carrots ; enterohemorrhagic Escherichia coli ; food safety ; grapefruits ; heat treatment ; irradiation ; onions ; seed extracts ; shelf life ; synergism ; ultraviolet radiation ; zinc oxide
    Language English
    Dates of publication 2022-08
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1027805-9
    ISSN 0956-7135
    ISSN 0956-7135
    DOI 10.1016/j.foodcont.2022.109027
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Age-Related Difference in Weight Change and All-Cause Mortality in Middle-Aged and Older Korean Populations: Korean Longitudinal Study of Aging.

    Suh, Jungki / Cho, Yoon Jeong / Kim, Hyun Ji / Choi, Seong Soo

    Korean journal of family medicine

    2021  Volume 42, Issue 4, Page(s) 297–302

    Abstract: Background: Obesity is associated with increased mortality as a significant risk factor for chronic diseases, including cardiovascular diseases and cancer. Several people believe that weight gain is harmful, and weight loss helps maintain health. ... ...

    Abstract Background: Obesity is associated with increased mortality as a significant risk factor for chronic diseases, including cardiovascular diseases and cancer. Several people believe that weight gain is harmful, and weight loss helps maintain health. However, some studies have shown that weight loss, particularly among older adults, is more likely to increase the risk of mortality than weight gain.
    Methods: We used data for the cohort of the Korean Longitudinal Study of Aging, which is a nationwide stratified multi-stage sample of adults aged 45 years. The all-cause mortality risk was assessed using the survival status and the number of months of survival calculated from 2006 (baseline year) to 2016. Cox proportional hazard regression were used to study the causal link between weight change and all-cause mortality risk.
    Results: The results showed interactive associations between weight loss and mortality among middle-aged and older adults. The hazard ratio was 1.62 (95% confidence interval [CI], 1.10-2.40) for the participants aged 45-65 years with weight losses greater than 5 kg and 1.56 (95% CI, 1.29-1.89) for those older than 65 years with weight losses greater than 5 kg. The results for the group with weight gain above 5 kg were not significant. Middle-aged and older men showed an increase in all-cause mortality associated with weight loss of more than 5 kg, but only the older women showed significant results.
    Conclusion: This large-scale cohort study in Korea showed a relationship between weight loss and all-cause mortality in middle-aged and older individuals.
    Language English
    Publishing date 2021-07-20
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2674300-0
    ISSN 2092-6715 ; 2005-6443
    ISSN (online) 2092-6715
    ISSN 2005-6443
    DOI 10.4082/kjfm.20.0170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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