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  1. Article ; Online: Randomized comparison of in vivo performance of TearLab® and I-PEN® osmometry in normal dogs.

    Kim, Hyun-Wook / Kim, Joon-Young

    Veterinary ophthalmology

    2023  Volume 26, Issue 5, Page(s) 440–445

    Abstract: Objective: To compare tear film (TF) osmolarity measured using TearLab® and I-PEN® osmometers in the same dogs without any ocular surface disease.: Animal studied: Fifty-two dogs (98 eyes) of different breeds were evaluated.: Procedures: Tear film ...

    Abstract Objective: To compare tear film (TF) osmolarity measured using TearLab® and I-PEN® osmometers in the same dogs without any ocular surface disease.
    Animal studied: Fifty-two dogs (98 eyes) of different breeds were evaluated.
    Procedures: Tear film (TF) osmolarity was evaluated at 2-min intervals. The test was randomly determined, and single measurements were performed using each osmometer. Subsequently, complete ophthalmologic examinations were performed based on Schirmer tear test-1 (STT-1) analysis, tear film breakup time (TFBUT), and slit-lamp biomicroscopy. For each osmometer, the mean ± standard deviation of the TF osmolarity was calculated, and a paired Student's t-test was used to compare the values obtained. Pearson correlation analysis was performed to assess the association between osmolarity and other values such as STT-1, TFBUT, and age.
    Results: Tear film osmolarity determined using TearLab® (340.42 ± 15.87 mOsm/L) and I-PEN® (321.58 ± 17.39 mOsm/L) were significantly different (p < .001). However, statistical significance could not be confirmed between osmolarity and other values, such as STT-1, TFBUT, and age.
    Conclusions: In dogs, the TF osmolarity values obtained using TearLab® tend to be higher than those obtained using I-PEN®, contrary to that observed in humans. These findings can serve as a reference for establishing normal values for each osmometer for clinical use in measuring TF osmolarity in dogs.
    MeSH term(s) Animals ; Dogs ; Dog Diseases ; Eye ; Lacerations/veterinary ; Osmolar Concentration ; Osmometry/veterinary ; Slit Lamp Microscopy ; Tears
    Language English
    Publishing date 2023-08-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/vop.13140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Physicochemical Properties of Mixed Gelatin Gels with Soy and Whey Proteins.

    Song, Dong-Heon / Yang, Na-Eun / Ham, Youn-Kyung / Kim, Hyun-Wook

    Gels (Basel, Switzerland)

    2024  Volume 10, Issue 2

    Abstract: The physicochemical properties of the mixed gelatin gels with soy and whey proteins were investigated to develop the gel base with a soft texture and abundant essential amino acids for the elderly. Gelatin-only gel (control) was prepared at 6% ( ...

    Abstract The physicochemical properties of the mixed gelatin gels with soy and whey proteins were investigated to develop the gel base with a soft texture and abundant essential amino acids for the elderly. Gelatin-only gel (control) was prepared at 6% (
    Language English
    Publishing date 2024-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2813982-3
    ISSN 2310-2861 ; 2310-2861
    ISSN (online) 2310-2861
    ISSN 2310-2861
    DOI 10.3390/gels10020124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Randomized comparison of in vivo performance of TearLab® and I‐PEN® osmometry in normal dogs

    Kim, Hyun‐wook / Kim, Joon‐Young

    Veterinary Ophthalmology. 2023 Sept., v. 26, no. 5 p.440-445

    2023  

    Abstract: OBJECTIVE: To compare tear film (TF) osmolarity measured using TearLab® and I‐PEN® osmometers in the same dogs without any ocular surface disease. ANIMAL STUDIED: Fifty‐two dogs (98 eyes) of different breeds were evaluated. PROCEDURES: Tear film (TF) ... ...

    Abstract OBJECTIVE: To compare tear film (TF) osmolarity measured using TearLab® and I‐PEN® osmometers in the same dogs without any ocular surface disease. ANIMAL STUDIED: Fifty‐two dogs (98 eyes) of different breeds were evaluated. PROCEDURES: Tear film (TF) osmolarity was evaluated at 2‐min intervals. The test was randomly determined, and single measurements were performed using each osmometer. Subsequently, complete ophthalmologic examinations were performed based on Schirmer tear test‐1 (STT‐1) analysis, tear film breakup time (TFBUT), and slit‐lamp biomicroscopy. For each osmometer, the mean ± standard deviation of the TF osmolarity was calculated, and a paired Student's t‐test was used to compare the values obtained. Pearson correlation analysis was performed to assess the association between osmolarity and other values such as STT‐1, TFBUT, and age. RESULTS: Tear film osmolarity determined using TearLab® (340.42 ± 15.87 mOsm/L) and I‐PEN® (321.58 ± 17.39 mOsm/L) were significantly different (p < .001). However, statistical significance could not be confirmed between osmolarity and other values, such as STT‐1, TFBUT, and age. CONCLUSIONS: In dogs, the TF osmolarity values obtained using TearLab® tend to be higher than those obtained using I‐PEN®, contrary to that observed in humans. These findings can serve as a reference for establishing normal values for each osmometer for clinical use in measuring TF osmolarity in dogs.
    Keywords animals ; ophthalmology ; osmolarity ; standard deviation ; t-test
    Language English
    Dates of publication 2023-09
    Size p. 440-445.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/vop.13140
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Strategy to improve synaptic behavior of ion-actuated synaptic transistors-the use of ion blocking layer to improve state retention.

    Jeon, Seonuk / Tessler, Nir / Kim, Nayeon / Hong, Eunryeong / Kim, Hyun Wook / Woo, Jiyong

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5030

    Abstract: Synaptic transistors (STs) with a gate/electrolyte/channel stack, where mobile ions are electrically driven across the solid electrolyte, have been considered as analog weight elements for neuromorphic computing. The current ( ... ...

    Abstract Synaptic transistors (STs) with a gate/electrolyte/channel stack, where mobile ions are electrically driven across the solid electrolyte, have been considered as analog weight elements for neuromorphic computing. The current (I
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55681-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Early-Onset Generalized Pustular Psoriasis of Pregnancy Following Hydroxychloroquine Use.

    Ryoo, Young-Wook / Yun, Ji-Min / Kim, Hyun-Wook / Kim, Sung-Ae

    Annals of dermatology

    2023  Volume 35, Issue Suppl 1, Page(s) S43–S47

    Abstract: Generalized pustular psoriasis of pregnancy (GPPP), characterized by widespread sterile pustules and erythematous patches with systemic symptoms such as fever, is a rare form of pustular psoriasis. GPPP typically occurs in the third trimester of ... ...

    Abstract Generalized pustular psoriasis of pregnancy (GPPP), characterized by widespread sterile pustules and erythematous patches with systemic symptoms such as fever, is a rare form of pustular psoriasis. GPPP typically occurs in the third trimester of pregnancy and can be triggered by various factors such as infections, hypocalcemia, and drugs including
    Language English
    Publishing date 2023-10-28
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 1012662-4
    ISSN 2005-3894 ; 1013-9087
    ISSN (online) 2005-3894
    ISSN 1013-9087
    DOI 10.5021/ad.21.062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Effects of Toxic Heavy Metal Salts on Oxidative Quality Deterioration in Ground Pork Model during Aerobic Display Storage.

    Ham, Youn-Kyung / Song, Dong-Heon / Kim, Hyun-Wook

    Antioxidants (Basel, Switzerland)

    2022  Volume 11, Issue 7

    Abstract: The contamination of toxic heavy metals in meat production and processing can cause the oxidative deterioration of processed meat products. Aside from the possible mechanisms of toxic heavy metals on pro-oxidative reaction, little is known about the ... ...

    Abstract The contamination of toxic heavy metals in meat production and processing can cause the oxidative deterioration of processed meat products. Aside from the possible mechanisms of toxic heavy metals on pro-oxidative reaction, little is known about the potential impacts of toxic heavy metal contamination on meat quality attributes within permitted maximum residual levels. Therefore, the objective of this study was to determine the influence of the intentional contamination of toxic heavy metals on the oxidative deterioration in ground pork models during aerobic display storage. Four types of toxic heavy metal salts (As2O3, CdCl2, K2Cr2O7, and Pb(NO3)2) were mixed with ground pork at two different levels (maximum residue limit and its half level), PVC-wrapped, and displayed in a 4 °C showcase equipped with continuous fluorescent natural white light (1400 l×, color temperature = 6500 K). The contamination of toxic heavy metals significantly decreased the redness of ground pork, and rapidly increased the hue angle. The contamination of Cd and Cr equivalent to maximum residue levels (0.05 and 1.0 mg/kg, respectively) could increase the formation of peroxides, 2-thiobarbituric acid reactive substances, and carbonyls, along with an immediate decrease in total reducing activity. However, there was no difference in protein thiol content between treatments (p > 0.05). These results indicate that contamination of certain toxic heavy metals, particularly Cd and Cr, would accelerate discoloration, lipid oxidation, and carbonyl formation of ground pork during aerobic storage.
    Language English
    Publishing date 2022-06-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox11071310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Quality Characteristics of Senior-Friendly Gelatin Gels Formulated with Hot Water Extract from Red Maple Leaf as a Novel Anthocyanin Source.

    Song, Dong-Heon / Gu, Tae-Wan / Kim, Hyun-Wook

    Foods (Basel, Switzerland)

    2021  Volume 10, Issue 12

    Abstract: The objectives of this study were to evaluate antioxidant capacity of hot water extract from red maple leaf with different extraction times (experiment I) and to determine their impacts on color, free anthocyanin content, and hardness of gelatin gels ( ... ...

    Abstract The objectives of this study were to evaluate antioxidant capacity of hot water extract from red maple leaf with different extraction times (experiment I) and to determine their impacts on color, free anthocyanin content, and hardness of gelatin gels (experiment II). In experiment I, hot water extraction time (30, 60, 120, 180, and 360 min at 60 °C) was fixed as a main effect. The different extraction times had no impacts on total polyphenol content and DPPH radical scavenging activity (
    Language English
    Publishing date 2021-12-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods10123074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Proteolytic Activity of Silkworm Thorn (

    Yang, Na-Eun / Lee, Da-Hoon / Hwang, Jun / Son, Woo-Young / Kim, Kyeong-Soo / Kim, Gwang-Yeon / Kim, Hyun-Wook

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 3

    Abstract: This study aimed to isolate the proteolytic fraction from the silkworm thorn fruit ( ...

    Abstract This study aimed to isolate the proteolytic fraction from the silkworm thorn fruit (
    MeSH term(s) Animals ; Humans ; Hydrolysis ; Bombyx/metabolism ; Papain/metabolism ; Fruit/metabolism ; Powders ; Peptide Hydrolases/metabolism ; Whey Proteins ; Maclura ; Soybean Proteins ; Subtilisins/metabolism ; Ethanol
    Chemical Substances Papain (EC 3.4.22.2) ; Powders ; Peptide Hydrolases (EC 3.4.-) ; Whey Proteins ; Soybean Proteins ; Subtilisins (EC 3.4.21.-) ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2024-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29030693
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Definition of a Localized Conducting Path via Suppressed Charge Injection in Oxide Memristors for Stable Practical Hardware Neural Networks.

    Kim, Hyeongwook / Lee, Jihwan / Kim, Hyun Wook / Woo, Jiyong / Kim, Min-Hwi / Lee, Sin-Hyung

    ACS applied materials & interfaces

    2023  

    Abstract: Oxide-based memristors have been demonstrated as suitable options for memory components in neuromorphic systems. In such devices, the resistive switching characteristics are caused by the formation of conductive filaments (CFs) comprising oxygen ... ...

    Abstract Oxide-based memristors have been demonstrated as suitable options for memory components in neuromorphic systems. In such devices, the resistive switching characteristics are caused by the formation of conductive filaments (CFs) comprising oxygen vacancies. Thus, the electrical performance is primarily governed by the CF structure. Despite various approaches for regulating the oxygen vacancy distributions in oxide memristors, controlling the CF structure without modifying the device configuration related to material compatibility is still a challenge. This study demonstrates an effective strategy for localizing CF distributions in memristors by suppressing charge injection during the formation of conducting paths. As the injected charge quantity is reduced in the electroforming process of the oxide memristor, the CF distributions become narrower, leading to more reproducible and stable resistive switching characteristics in the device. Based on these findings, a reliable hardware neural network comprising oxide memristors is constructed to recognize complex images. The developed memristor has been employed as a synaptic memory component in systems without degradation for a long time. This promising concept of oxide memristors acting as stable synaptic components holds great potential for developing practical neuromorphic systems and their expansion into artificial intelligent systems.
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c13514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Physicochemical Properties of Chicken Breast and Thigh as Affected by Sous-Vide Cooking Conditions.

    Noh, Sin-Woo / Song, Dong-Heon / Ham, Youn-Kyung / Yang, Na-Eun / Kim, Hyun-Wook

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 13

    Abstract: Sous-vide is a cooking method used to improve the tenderness and juiciness of chicken breast. However, the comparative changes in meat quality attributes of sous-vide cooked chicken breast and thigh muscles are not fully understood. The objective of this ...

    Abstract Sous-vide is a cooking method used to improve the tenderness and juiciness of chicken breast. However, the comparative changes in meat quality attributes of sous-vide cooked chicken breast and thigh muscles are not fully understood. The objective of this study was to investigate the effects of sous-vide cooking conditions, based on collagen denaturation temperature of intramuscular connective tissue, on the physicochemical properties of chicken breasts and thighs. Chicken breast and thigh were cooked at four sous-vide cooking conditions (55 °C for 3/6 h and 65 °C for 3/6 h) and conventional cooking at 75 °C (core temperature of 71 °C) as control. No significant differences in pH and lightness were found between the sous-vide cooking conditions. Moisture content, cooking loss, protein solubility, shear force, myofibrillar fragmentation index, and lipid oxidation were affected by sous-vide cooking conditions (
    Language English
    Publishing date 2023-07-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12132592
    Database MEDical Literature Analysis and Retrieval System OnLINE

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