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  1. AU="Kim, John S"
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  1. Article ; Online: A Crystal Ball for Hypoxia in Fibrotic Interstitial Lung Disease.

    Sood, Shweta / Kim, John S

    Annals of the American Thoracic Society

    2023  Volume 20, Issue 12, Page(s) 1705–1706

    MeSH term(s) Humans ; Lung Diseases, Interstitial ; Fibrosis ; Hypoxia
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202309-840ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5828: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  2. Article ; Online: Mapping the Proteomic Landscape of Radiological Lung Abnormalities.

    Maddali, Manoj V / Kim, John S / Oldham, Justin M

    American journal of respiratory and critical care medicine

    2024  Volume 209, Issue 9, Page(s) 1052–1054

    MeSH term(s) Humans ; Proteomics/methods ; Lung/diagnostic imaging ; Female ; Male ; Tomography, X-Ray Computed ; Lung Diseases/diagnostic imaging ; Middle Aged
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Research Support, Non-U.S. Gov't ; Journal Article ; Letter ; Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202402-0310ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Can Interstitial Lung Abnormalities Explain a High FVC in a Smoker With Emphysema?

    Paul, Tessy K / Kim, John S

    Chest

    2022  Volume 161, Issue 4, Page(s) 872–873

    MeSH term(s) Emphysema ; Humans ; Lung/diagnostic imaging ; Pulmonary Emphysema/diagnosis ; Pulmonary Emphysema/etiology ; Respiratory System Abnormalities ; Smokers
    Language English
    Publishing date 2022-03-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2021.11.039
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    Zs.MO 349: Show issues

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  4. Article: Letter to the Editor: Response by Authors.

    Kim, John S / Barr, R Graham

    Chronic obstructive pulmonary diseases (Miami, Fla.)

    2021  Volume 8, Issue 2, Page(s) 188–189

    Language English
    Publishing date 2021-04-28
    Publishing country United States
    Document type Letter
    ZDB-ID 2771715-X
    ISSN 2372-952X
    ISSN 2372-952X
    DOI 10.15326/jcopdf.2021.0225
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  5. Article: Case Report: Catheter-based mechanical thrombectomy using the Indigo aspiration system in a case of systemic-to-pulmonary shunt thrombosis.

    Soszyn, Natalie / Morgan, Gareth J / Kim, John S / Zablah, Jenny E

    Frontiers in pediatrics

    2023  Volume 11, Page(s) 1114044

    Abstract: A 53-day-old girl with absent right atrioventricular (AV) connection, malposed great vessels, and pulmonary atresia underwent placement of a central shunt on the sixth day of her life. Her postoperative course was complicated by progressive desaturation, ...

    Abstract A 53-day-old girl with absent right atrioventricular (AV) connection, malposed great vessels, and pulmonary atresia underwent placement of a central shunt on the sixth day of her life. Her postoperative course was complicated by progressive desaturation, and computed tomographic angiography (CTA) demonstrated near-complete occlusion of her left pulmonary artery (LPA). Angiography demonstrated a nonocclusive thrombus in the distal central shunt and a thrombus with complete occlusion of the LPA. The Indigo aspiration system (Penumbra) was used to remove the thrombus from the central shunt and LPA, allowing placement of a stent in the narrowed LPA. Subsequent angiography showed a wide patient central shunt and LPA. The Indigo aspiration system (Penumbra) provides a viable option for removing thrombus in a patients refractory to other methods.
    Language English
    Publishing date 2023-01-26
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1114044
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Does the Volume and Constitution of Cardiopulmonary Bypass Priming Fluids Affect Blood Loss After Cardiac Surgery in Children?

    Kim, John S / Ellis, W Cory / Ing, Richard J

    Journal of cardiothoracic and vascular anesthesia

    2022  Volume 36, Issue 6, Page(s) 1595–1597

    MeSH term(s) Blood Loss, Surgical ; Cardiac Surgical Procedures/adverse effects ; Cardiopulmonary Bypass/adverse effects ; Child ; Humans
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2022.01.006
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    Zs.A 2203: Show issues Location:
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    Zs.MO 31: Show issues

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  7. Article: Diagnostic Utility of Point-of-Care Ultrasound in the Pediatric Cardiac Intensive Care Unit.

    Persson, Jessica N / Kim, John S / Good, Ryan J

    Current treatment options in pediatrics

    2022  Volume 8, Issue 3, Page(s) 151–173

    Abstract: Purpose of review: This review summarizes the diverse uses of point-of-care ultrasound (POCUS) in critically ill children with congenital and acquired heart disease. Diagnostic utility and practicality of POCUS is reviewed. Importantly, the role of ... ...

    Abstract Purpose of review: This review summarizes the diverse uses of point-of-care ultrasound (POCUS) in critically ill children with congenital and acquired heart disease. Diagnostic utility and practicality of POCUS is reviewed. Importantly, the role of POCUS in the medical management of children in the cardiac intensive care unit is highlighted.
    Recent findings: The use of POCUS in critically ill pediatric patients has emerged as an essential diagnostic tool that enhances the physical examination and influences delivery of care. Assessment of a wide range of body systems and pathologies has been impacted by the use of POCUS. Recent studies have demonstrated the use of POCUS for evaluation of cardiac tamponade, pneumonia, vocal cord function, and loss of muscle mass in critically ill children (Hamilton et al. Pediatr Crit Care Med 22(10):e532-e539, 2021; Hoffmann et al. Pediatr Crit Care Med 22(10):889-897, 2021; Najgrodzka et al. Ultrasound Q 35(2):157 163, 2019; Alerhand et al. Pediatr Ann 50(10):e424-e431, 2021).
    Summary: POCUS is a non-invasive, low-risk, imaging modality that can be used to diagnose and help guide management of critically ill children in the cardiac intensive care unit. POCUS can be performed by an intensivist at the patient's bedside with real-time interpretation, leading to rapid clinical decision-making and the hope of improving patient outcomes.
    Supplementary information: The online version contains supplementary material available at 10.1007/s40746-022-00250-1.
    Language English
    Publishing date 2022-07-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2198-6088
    ISSN 2198-6088
    DOI 10.1007/s40746-022-00250-1
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  8. Article: Survival of Children With Pulmonary Embolism Supported by Extracorporeal Membrane Oxygenation.

    Kim, John S / Barrett, Cindy S / Hyslop, Robert W / Buckvold, Shannon M / Gist, Katja M

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 877637

    Abstract: The purpose of this study was to describe the demographics and in-hospital mortality of children (<18 years) from 2007 to 2018 supported by Extracorporeal Membrane Oxygenation (ECMO) for a primary diagnosis of pulmonary embolism and reported to the ... ...

    Abstract The purpose of this study was to describe the demographics and in-hospital mortality of children (<18 years) from 2007 to 2018 supported by Extracorporeal Membrane Oxygenation (ECMO) for a primary diagnosis of pulmonary embolism and reported to the Extracorporeal Life Support Organization database. Fifty-six patients were identified and 54 were included in this analysis. A total of 33 patients (61%) survived. No differences in demographics or ECMO details (duration, mode, and support type) were found between survivors and non-survivors. When ECMO complications were compared, pulmonary bleeding occurred more frequently in non-survivors (23.8%,
    Language English
    Publishing date 2022-05-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.877637
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  9. Article ; Online: Nonlinear associations between computed tomography-measures of adiposity and long pentraxin-3 in the Multi-Ethnic Study of Atherosclerosis.

    Anderson, Michaela R / Kim, John S / Podolanczuk, Anna / Ding, Jingzhong / Al-Naamani, Nadine / Allison, Matthew / Christie, Jason / Diamond, Joshua

    Obesity science & practice

    2023  Volume 10, Issue 1, Page(s) e708

    Abstract: Objective: Long pentraxin-3 (PTX-3) is an acute phase protein associated with cardiovascular disease, lung injury, and mortality. We evaluated the association between computed tomography (CT)-measurements of adipose tissue and plasma levels of PTX-3.: ...

    Abstract Objective: Long pentraxin-3 (PTX-3) is an acute phase protein associated with cardiovascular disease, lung injury, and mortality. We evaluated the association between computed tomography (CT)-measurements of adipose tissue and plasma levels of PTX-3.
    Methods: We performed a cross-sectional analysis of community-dwelling adults enrolled in the multi-center Multiethnic Study of Atherosclerosis who underwent cardiac or abdominal CT and had available PTX-3 measurements.
    Results: There was a U-shaped association between pericardial adipose tissue volume (PAT), abdominal visceral adipose tissue area (VAT), hepatic attenuation, and PTX-3 levels, with extremes of adiposity associated with greater PTX-3 levels. Using multivariable-adjusted piecewise regression models, among participants with low PAT, every 1% increase in PAT volume was associated with a 13.8% decrease in PTX-3 (95% confidence interval [CI] -21.6 to -6.0); among participants with high PAT, every 1% increase in PAT volume was associated with a 6.0% increase in PTX-3 (95% CI -0.4 to 12.5). Results were similar for abdominal VAT and hepatic attenuation.
    Conclusions: In a cohort of community-dwelling adults, we demonstrated a "U-shaped" association between pericardial, abdominal visceral, and hepatic adiposity with PTX3 levels, suggesting that extreme adiposity is associated with greater circulating levels of PTX3. Further work is required to identify the mechanisms linking adiposity and PTX-3.
    Language English
    Publishing date 2023-11-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2836381-4
    ISSN 2055-2238 ; 2055-2238
    ISSN (online) 2055-2238
    ISSN 2055-2238
    DOI 10.1002/osp4.708
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  10. Article ; Online: Comparison of Pirfenidone and Nintedanib: Post Hoc Analysis of the CleanUP-IPF Study.

    Kim, John S / Murray, Susan / Yow, Eric / Anstrom, Kevin J / Kim, Hyun J / Flaherty, Kevin R / Martinez, Fernando J / Noth, Imre

    Chest

    2023  Volume 165, Issue 5, Page(s) 1163–1173

    Abstract: Background: Antifibrotics are effective in slowing FVC decline in idiopathic pulmonary fibrosis (IPF). However, whether antifibrotic type is differentially associated with FVC decline remains inconclusive.: Research question: Are there significant ... ...

    Abstract Background: Antifibrotics are effective in slowing FVC decline in idiopathic pulmonary fibrosis (IPF). However, whether antifibrotic type is differentially associated with FVC decline remains inconclusive.
    Research question: Are there significant differences in 12-month FVC decline between pirfenidone and nintedanib?
    Study design and methods: A post hoc analysis was performed using the Clinical Efficacy of Antimicrobial Therapy Strategy Using Pragmatic Design in IPF (CleanUP-IPF) trial (No. NCT02759120). Participants who reported using pirfenidone or nintedanib on enrollment into the trial were in the primary analysis. Spirometry was scheduled at baseline and the 12- and 24-month study visits. Linear mixed-effects models with random intercept and slope were used to examine changes in FVC over time. Models were adjusted for age, sex, smoking history, coronary artery disease history, baseline FVC, and 12-month spline term. Survival and nonelective respiratory hospitalization by antifibrotic type were determined using Cox regression models with adjustment for age, sex, smoking history, coronary artery disease history, and baseline FVC and diffusing capacity for carbon monoxide.
    Results: Out of the 513 participants with IPF randomized in the CleanUP-IPF trial, 407 reported using pirfenidone (n = 264, 65%) or nintedanib (n = 143, 35%). The pirfenidone group had more participants with a history of coronary artery disease than the nintedanib group (34.1% vs 20.3%, respectively). Patients treated with nintedanib had a higher 12-month visit FVC than patients treated with pirfenidone (mean difference, 106 mL; 95% CI, 34-178). This difference was attenuated at the 24-month study visit. There were no significant differences in overall survival and nonelective respiratory hospitalization between the pirfenidone- and nintedanib-treated groups.
    Interpretation: Patients with IPF who used nintedanib had a slower 12-month FVC decline than pirfenidone in a post hoc analysis of a clinical trial.
    MeSH term(s) Humans ; Pyridones/therapeutic use ; Idiopathic Pulmonary Fibrosis/drug therapy ; Idiopathic Pulmonary Fibrosis/physiopathology ; Indoles/therapeutic use ; Male ; Female ; Aged ; Vital Capacity ; Middle Aged ; Antifibrotic Agents/therapeutic use ; Treatment Outcome
    Chemical Substances pirfenidone (D7NLD2JX7U) ; nintedanib (G6HRD2P839) ; Pyridones ; Indoles ; Antifibrotic Agents
    Language English
    Publishing date 2023-11-27
    Publishing country United States
    Document type Journal Article ; Comparative Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Multicenter Study
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.11.035
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