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Article ; Online: Development of digital mirror therapy for stroke-severe patients.

Kim, S B / Kye, S A / Lee, O S

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

2023 Volume 2023, Page(s) 1–4

Abstract: Mirror therapy (MT), which is used in the existing stroke rehabilitation environment, has significant limitations for use with severe stroke patients. Since mirrors only reflect symmetrical movement, allowing a patient to observe precise asymmetrical ... ...

Abstract	Mirror therapy (MT), which is used in the existing stroke rehabilitation environment, has significant limitations for use with severe stroke patients. Since mirrors only reflect symmetrical movement, allowing a patient to observe precise asymmetrical movement is impossible. This study proposes a new MT system by developing a pyramid hologram technology that uses delayed motion to create realistic images. Significant differences, observed via electroencephalogram, were shown in all motor cortex channels immediately after the event in the delayed condition when compared to before the event (C3: p < 0.001; Cz: p < 0.001, C4: p < 0.001). The illusion of asymmetrical movement using the proposed system can be applied to severe stroke patients to increase the positive outcome of rehabilitation.
MeSH term(s)	Humans ; Mirror Movement Therapy ; Stroke/therapy ; Stroke Rehabilitation/methods ; Movement ; Motor Cortex
Language	English
Publishing date	2023-12-11
Publishing country	United States
Document type	Journal Article
ISSN	2694-0604
ISSN (online)	2694-0604
DOI	10.1109/EMBC40787.2023.10340774
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Determination of the baseline tritium concentrations (HTO, TFWT and OBT) in soil and plants in Ontario, Canada

Kim, S.B. / Bredlaw, M. / Rousselle, H. / Bond, M. / Stuart, M.

Journal of environmental radioactivity. 2022 Mar., v. 243

2022

Abstract: Tritiated water (HTO), tissue free water tritium (TFWT) and organically bound tritium (OBT) activity concentrations in soil and plant leaves, collected at background areas in Ontario, were measured to quantify the current tritium baseline. Five ... ...

Abstract	Tritiated water (HTO), tissue free water tritium (TFWT) and organically bound tritium (OBT) activity concentrations in soil and plant leaves, collected at background areas in Ontario, were measured to quantify the current tritium baseline. Five representative background sites, based on their geological characteristics and residential populations, have been selected for this study.Undisturbed soils, plant leaves and surface water samples were collected at 5 sites (London, Kapuskasing, Thunder Bay, Elliot Lake and Cornwall areas) in 2015. Water sample HTO activity concentrations were measured using Liquid Scintillation Counting (LSC, ALOKA), and HTO activity concentrations for soil and TFWT for plant leaves were measured by LSC (Quantulus 1220) on water extracted from frozen samples using a freeze-drying vacuum system equipped with a liquid nitrogen trap. Plant leaf OBT levels were obtained by combustion of rinsed freeze-dried samples using a Parr combustion system, while soil OBT values were obtained using a tube furnace combustion system. Combustion water was distilled before being counted by LSC (Quantulus 1220).HTO activity concentrations were found to range between 1.4 and 2.0 Bq/L (MDA = 0.5 Bq/L) in surface water and soil samples. TFWT values were less than the minimum detectable activity (MDA = 3.5 Bq/L) in plant leaves. In contrast, OBT activity concentrations (MDA = 5 Bq/L) ranged from 5.7 to 17.1 Bq/L in plant leaves and 8.3–20.7 Bq/L in surface soil (0–5 cm depth). The overall OBT activity concentrations were higher in the London and the Cornwall areas. Lower levels were measured near Thunder Bay, Kapuskasing and Elliot Lake. There was no obvious relationship between soil OBT activity concentrations and soil types.The results provide the current tritium (HTO, TFWT and OBT) baseline values in Ontario. These values will be helpful for use as background locations for the evaluation of past and future environmental tritium inputs associated with nuclear facilities, and will be taken into account when evaluating the environmental impact of nuclear facilities in Ontario. Since samples in this study were primarily taken in wooded areas, some questions remain regarding the possibility that soil samples in open, non-wooded areas could show different HTO and OBT contents than those presented in this study.
Keywords	combustion ; environmental impact ; freeze drying ; furnaces ; lakes ; leaves ; liquid nitrogen ; liquids ; radioactivity ; soil ; surface water ; tritiated water ; tritium ; Ontario
Language	English
Dates of publication	2022-03
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	1483112-0
ISSN	1879-1700 ; 0265-931X
ISSN (online)	1879-1700
ISSN	0265-931X
DOI	10.1016/j.jenvrad.2021.106810
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Article: Reply: Vitamin C as a Possible Therapy for COVID-19

Kim, S. B. / Yeom, J. S.

Infection and Chemotherapy

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #918280
Database	COVID19

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Article ; Online: Determination of the baseline tritium concentrations (HTO, TFWT and OBT) in soil and plants in Ontario, Canada.

Kim, S B / Bredlaw, M / Rousselle, H / Bond, M / Stuart, M

Journal of environmental radioactivity

2022 Volume 243, Page(s) 106810

Abstract	Tritiated water (HTO), tissue free water tritium (TFWT) and organically bound tritium (OBT) activity concentrations in soil and plant leaves, collected at background areas in Ontario, were measured to quantify the current tritium baseline. Five representative background sites, based on their geological characteristics and residential populations, have been selected for this study. Undisturbed soils, plant leaves and surface water samples were collected at 5 sites (London, Kapuskasing, Thunder Bay, Elliot Lake and Cornwall areas) in 2015. Water sample HTO activity concentrations were measured using Liquid Scintillation Counting (LSC, ALOKA), and HTO activity concentrations for soil and TFWT for plant leaves were measured by LSC (Quantulus 1220) on water extracted from frozen samples using a freeze-drying vacuum system equipped with a liquid nitrogen trap. Plant leaf OBT levels were obtained by combustion of rinsed freeze-dried samples using a Parr combustion system, while soil OBT values were obtained using a tube furnace combustion system. Combustion water was distilled before being counted by LSC (Quantulus 1220). HTO activity concentrations were found to range between 1.4 and 2.0 Bq/L (MDA = 0.5 Bq/L) in surface water and soil samples. TFWT values were less than the minimum detectable activity (MDA = 3.5 Bq/L) in plant leaves. In contrast, OBT activity concentrations (MDA = 5 Bq/L) ranged from 5.7 to 17.1 Bq/L in plant leaves and 8.3-20.7 Bq/L in surface soil (0-5 cm depth). The overall OBT activity concentrations were higher in the London and the Cornwall areas. Lower levels were measured near Thunder Bay, Kapuskasing and Elliot Lake. There was no obvious relationship between soil OBT activity concentrations and soil types. The results provide the current tritium (HTO, TFWT and OBT) baseline values in Ontario. These values will be helpful for use as background locations for the evaluation of past and future environmental tritium inputs associated with nuclear facilities, and will be taken into account when evaluating the environmental impact of nuclear facilities in Ontario. Since samples in this study were primarily taken in wooded areas, some questions remain regarding the possibility that soil samples in open, non-wooded areas could show different HTO and OBT contents than those presented in this study.
MeSH term(s)	Ontario ; Radiation Monitoring ; Soil ; Soil Pollutants, Radioactive/analysis ; Tritium/analysis
Chemical Substances	Soil ; Soil Pollutants, Radioactive ; Tritium (10028-17-8)
Language	English
Publishing date	2022-01-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1483112-0
ISSN	1879-1700 ; 0265-931X
ISSN (online)	1879-1700
ISSN	0265-931X
DOI	10.1016/j.jenvrad.2021.106810
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: First Report of Leaf Blight Caused by Pantoea agglomerans on Rice in Korea.

Lee, H B / Hong, J P / Kim, S B

Plant disease

2019 Volume 94, Issue 11, Page(s) 1372

Abstract: In September 2009, leaf blights were observed on rice (Oryza sativa L., variety Dongjin 1 and Hopyeong) in paddy fields located in Gwangyang and Naju, Jeonnam Province, Korea. Lesions appeared first as water-soaked stripes or light brown-to-slightly ... ...

Abstract	In September 2009, leaf blights were observed on rice (Oryza sativa L., variety Dongjin 1 and Hopyeong) in paddy fields located in Gwangyang and Naju, Jeonnam Province, Korea. Lesions appeared first as water-soaked stripes or light brown-to-slightly reddish spots on the upper blades of the leaves, ultimately causing leaf blight and stalk rot. Ten strains of bacteria were isolated from the blighted leaf samples and four isolates (EML-ORY1, -ORY2, -ORY3, and -ORY4) suspected to be Pantoea spp. were selected on the basis of colony types and sampling sites. The isolates readily grew at 27 to 32°C but growth was significantly lower at 35°C. Using the API 20E system, EML-ORY1, 2, and 3 showed the same reaction patterns and gave 15 positive reactions whereas EML-ORY4 gave 11 positive reactions, but results were negative for arginine dihydrolase, citrate utilization, sorbitol fermentation, and rhamnose fermentation. All strains were considerably different from Pantoea agglomerans ATCC27155, which produced nine positive reactions. The strains were identified based on the 16S rRNA gene sequence analyses. A neighbor-joining tree was generated for the four isolates using PHYLIP with the following known bacterial strains: P. agglomerans DSM3493; P. vagans LMG24199; P. eucalypti LMG24197; P. ananatis ATCC19321; and Kluyvera georgiana ATCC51603. The four isolates from rice formed a monophyletic cluster and were most closely related to P. agglomerans DSM3493 (GenBank AJ2334231) with an average 16S rRNA sequence similarity of 99.0%. GenBank Accession numbers for the four isolates are: EML-ORY1, HM854282; -ORY2, HM854283; -ORY3, HM854284; and -ORY4, HM854285. On the basis of molecular phylogenetic analyses and API 20E test, we determined that the causal pathogen might be a subspecies of P. agglomerans. Pathogenicity tests were performed on 2-week-old rice seedlings (variety Hopyeong) in duplicate with bacterial suspensions containing 1.5 × 10
Language	English
Publishing date	2019-02-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	754182-x
ISSN	0191-2917
ISSN	0191-2917
DOI	10.1094/PDIS-05-10-0374
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Article: Feasibility Study on Immobilization of Radioactive Cobalt and BaSO4 Waste Powder Using Low-Temperature Sintering

Eun, Hee-Chul / Chang, N. O. / Kim, S. B. / Seo, B. K.

Water, air, and soil pollution. 2021 Aug., v. 232, no. 8

2021

Abstract: BaSO₄ waste powder containing radionuclides generated from nuclear facilities must be immobilized into a stable waste form for final disposal. In this study, the immobilization of BaSO₄ waste powder containing simulant radioactive cobalt by low- ... ...

Abstract	BaSO₄ waste powder containing radionuclides generated from nuclear facilities must be immobilized into a stable waste form for final disposal. In this study, the immobilization of BaSO₄ waste powder containing simulant radioactive cobalt by low-temperature sintering was evaluated. A simulated decontamination waste was prepared as a BaSO₄ waste powder containing simulant radioactive cobalt, and Bi₂O₃-B₂O₃-ZnO-SiO₂ glass was used as a binding material for the immobilization. The simulated waste was immobilized into a monolithic waste form at 550 °C without the SO₂ gas generation. The glass was converted into crystal structures during the immobilization. The waste form had a high bulk density (5.05 g/cm³), and it showed a good compressive strength (21.92 MPa). It was also confirmed that the waste form had a high chemical durability through a semi-dynamic leaching test. In particular, the average leaching index of Co was 13.18. These results show that the immobilization has a potential application to BaSO₄ waste powder containing radionuclides for final disposal.
Keywords	air ; bulk density ; cobalt ; compression strength ; decontamination ; durability ; feasibility studies ; glass ; soil pollution ; wastes ; water
Language	English
Dates of publication	2021-08
Size	p. 333.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	120499-3
ISSN	1573-2932 ; 0049-6979 ; 0043-1168
ISSN (online)	1573-2932
ISSN	0049-6979 ; 0043-1168
DOI	10.1007/s11270-021-05292-z
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Tislelizumab versus chemotherapy as second-line treatment of advanced or metastatic esophageal squamous cell carcinoma (RATIONALE 302): impact on health-related quality of life.

Van Cutsem, E / Kato, K / Ajani, J / Shen, L / Xia, T / Ding, N / Zhan, L / Barnes, G / Kim, S-B

ESMO open

2022 Volume 7, Issue 4, Page(s) 100517

Abstract: Background: RATIONALE 302 (NCT03430843) an open-label, phase III study of second-line treatment of advanced/metastatic esophageal squamous cell carcinoma (ESCC), reported that tislelizumab, relative to investigator-chosen chemotherapy (ICC), was ... ...

Abstract	Background: RATIONALE 302 (NCT03430843) an open-label, phase III study of second-line treatment of advanced/metastatic esophageal squamous cell carcinoma (ESCC), reported that tislelizumab, relative to investigator-chosen chemotherapy (ICC), was associated with improvements in overall survival and a favorable safety profile. This study assessed the health-related quality of life (HRQoL) and ESCC-related symptoms of patients in RATIONALE 302. Methods: Adults with advanced/metastatic ESCC whose disease progressed following prior systemic therapy were randomized 1 : 1 to receive either tislelizumab or ICC (paclitaxel, docetaxel, or irinotecan). HRQoL was measured using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 items (EORTC QLQ-C30), the EORTC Quality of Life Questionnaire Oesophageal Cancer Module 18 items (QLQ-OES18), and the EuroQoL Five-Dimensions Five-Levels (EQ-5D-5L) visual analogue scale. Mixed effect modeling for repeated measurements examined changes from baseline to weeks 12 and 18. The Kaplan-Meier method was used to examine time to deterioration. Results: Overall, 512 patients were randomized to tislelizumab (n = 256) or ICC (n = 256). The tislelizumab arm maintained QLQ-C30 global health status/quality whereas the ICC arm worsened at week 12 {difference in least square (LS) mean change: 5.8 [95% confidence interval (CI): 2.0-9.5], P = 0.0028} and week 18 [difference in LS mean change: 8.1 (95% CI: 3.4-12.8), P = 0.0008]. Physical functioning (week 18) and fatigue (weeks 12 and 18) worsened less in the tislelizumab compared with the ICC arm. The tislelizumab arm improved in reflux symptoms, whereas the ICC worsened at week 12 [difference in LS mean change: -4.1 (95% CI: -7.6 to -0.6), P = 0.0229]. The visual analogue scale remained consistent in the tislelizumab arm whereas it worsened in the ICC arm. The hazard of time to deterioration was lower in tislelizumab patients compared with ICC for physical functioning and reflux. Conclusions: HRQoL, including fatigue symptoms and physical functioning, was maintained in patients with advanced or metastatic ESCC receiving tislelizumab compared with ICC-treated patients. These results provide additional support for the benefits of tislelizumab in this patient population.
MeSH term(s)	Adult ; Antibodies, Monoclonal, Humanized ; Esophageal Neoplasms ; Esophageal Squamous Cell Carcinoma ; Fatigue ; Humans ; Quality of Life
Chemical Substances	Antibodies, Monoclonal, Humanized ; tislelizumab (0KVO411B3N)
Language	English
Publishing date	2022-07-01
Publishing country	England
Document type	Clinical Trial, Phase III ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ISSN	2059-7029
ISSN (online)	2059-7029
DOI	10.1016/j.esmoop.2022.100517
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: OBT analysis method using polyethylene beads for limited quantities of animal tissue.

Kim, S B / Stuart, M

Journal of environmental radioactivity

2015 Volume 146, Page(s) 51–55

Abstract: This study presents a polyethylene beads method for OBT determination in animal tissues and animal products for cases where the amount of water recovered by combustion is limited by sample size or quantity. In the method, the amount of water recovered ... ...

Abstract	This study presents a polyethylene beads method for OBT determination in animal tissues and animal products for cases where the amount of water recovered by combustion is limited by sample size or quantity. In the method, the amount of water recovered after combustion is enhanced by adding tritium-free polyethylene beads to the sample prior to combustion in an oxygen bomb. The method reduces process time by allowing the combustion water to be easily collected with a pipette. Sufficient water recovery was achieved using the polyethylene beads method when 2 g of dry animal tissue or animal product were combusted with 2 g of polyethylene beads. Correction factors, which account for the dilution due to the combustion water of the beads, are provided for beef, chicken, pork, fish and clams, as well as egg, milk and cheese. The method was tested by comparing its OBT results with those of the conventional method using animal samples collected on the Chalk River Laboratories (CRL) site. The results determined that the polyethylene beads method added no more than 25% uncertainty when appropriate correction factors are used.
MeSH term(s)	Animals ; Dairy Products/analysis ; Eggs/analysis ; Food Contamination, Radioactive/analysis ; Meat/analysis ; Microspheres ; Polyethylene ; Radiation Monitoring/methods ; Tritium/analysis
Chemical Substances	Tritium (10028-17-8) ; Polyethylene (9002-88-4)
Language	English
Publishing date	2015-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1483112-0
ISSN	1879-1700 ; 0265-931X
ISSN (online)	1879-1700
ISSN	0265-931X
DOI	10.1016/j.jenvrad.2015.04.002
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Distribution of organically bound tritium (OBT) activity concentrations in aquatic biota from eastern Canada.

Kim, S B / Bredlaw, M / Rousselle, H / Stuart, M

Journal of environmental radioactivity

2019 Volume 208-209, Page(s) 105997

Abstract: A survey of eastern Canadian biota was conducted to determine the distribution of activity concentrations of organically bound tritium (OBT). Fish samples were collected from Lake Ontario and the St. Lawrence River in areas continuously receiving inputs ... ...

Abstract	A survey of eastern Canadian biota was conducted to determine the distribution of activity concentrations of organically bound tritium (OBT). Fish samples were collected from Lake Ontario and the St. Lawrence River in areas continuously receiving inputs of tritiated water (HTO) from operating nuclear power plants, and from Lake Nipissing, a background area. Components of their aquatic environments were sampled. The data collected also provides some insight on how tritium activity concentrations in ambient water influence tissue free water tritium (TFWT) and OBT activity concentrations in biological tissues. Using an ALOKA liquid scintillation system, fish TFWT and OBT were quantified. Fish TFWT averaged 1.6 ± 0.1 Bq/L in Lake Nipissing and 3.1 ± 0.3 Bq/L in Lake Ontario. In contrast, TFWT ranged from 11.1 to 80.8 Bq/L in the St. Lawrence River near the Gentilly-2 Canada Deuterium Uranium (CANDU) site. Fish tissue OBT levels were 4.0 ± 0.4 Bq/L and 5.3 ± 0.2 Bq/L for Lake Nipissing and Lake Ontario, respectively, and between 18.1 and 134.2 Bq/L for CANDU sites. The activity concentrations of TFWT and OBT were reviewed for algae, freshwater mussel and various fish samples collected near Gentilly-2, Pickering and Darlington Nuclear Power Generating Stations. TFWT in aquatic biota was found to correlate with the tritium activity concentrations measured in waters at the time of sampling (TFWT/HTO of ambient water was 0.3-4.3). The OBT concentration factors (OBT/HTO of ambient water) were found to be higher in freshwater mussels (between 17 and 47) compared to algae and fish (0.3-10). These results point to a heterogeneous distribution of biota OBT content in these aquatic ecosystems. It was also noted that all fish and algae samples were found to be within the range of tritium activity concentrations that has been historically measured in the same waters. Values in freshwater mussels were above this range.
MeSH term(s)	Aquatic Organisms/chemistry ; Biota ; Ecosystem ; Ontario ; Radiation Monitoring ; Tritium/analysis ; Water Pollutants, Radioactive/analysis
Chemical Substances	Water Pollutants, Radioactive ; Tritium (10028-17-8)
Language	English
Publishing date	2019-06-20
Publishing country	England
Document type	Journal Article
ZDB-ID	1483112-0
ISSN	1879-1700 ; 0265-931X
ISSN (online)	1879-1700
ISSN	0265-931X
DOI	10.1016/j.jenvrad.2019.105997
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Article: OBT analysis method using polyethylene beads for limited quantities of animal tissue

Kim, S.B / M. Stuart

Journal of environmental radioactivity. 2015 Aug., v. 146

2015

Abstract	This study presents a polyethylene beads method for OBT determination in animal tissues and animal products for cases where the amount of water recovered by combustion is limited by sample size or quantity. In the method, the amount of water recovered after combustion is enhanced by adding tritium-free polyethylene beads to the sample prior to combustion in an oxygen bomb. The method reduces process time by allowing the combustion water to be easily collected with a pipette. Sufficient water recovery was achieved using the polyethylene beads method when 2Â g of dry animal tissue or animal product were combusted with 2Â g of polyethylene beads. Correction factors, which account for the dilution due to the combustion water of the beads, are provided for beef, chicken, pork, fish and clams, as well as egg, milk and cheese. The method was tested by comparing its OBT results with those of the conventional method using animal samples collected on the Chalk River Laboratories (CRL) site. The results determined that the polyethylene beads method added no more than 25% uncertainty when appropriate correction factors are used.
Keywords	animal tissues ; beef ; cheeses ; chickens ; clams ; combustion ; eggs ; fish ; milk ; oxygen ; polyethylene ; pork ; rivers ; uncertainty
Language	English
Dates of publication	2015-08
Size	p. 51-55.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	1483112-0
ISSN	1879-1700 ; 0265-931X
ISSN (online)	1879-1700
ISSN	0265-931X
DOI	10.1016/j.jenvrad.2015.04.002
Database	NAL-Catalogue (AGRICOLA)

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