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  1. Article: Roles of Tissue Inhibitor of Metalloproteinase-1 in Severe Asthma.

    Kim, Sang-Heon

    Allergy, asthma & immunology research

    2023  Volume 15, Issue 4, Page(s) 416–418

    Language English
    Publishing date 2023-07-19
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2545725-1
    ISSN 2092-7363 ; 2092-7355
    ISSN (online) 2092-7363
    ISSN 2092-7355
    DOI 10.4168/aair.2023.15.4.416
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  2. Article: Severe Cutaneous Adverse Reactions Caused by Anti-Tubercular Drugs.

    Kim, Sang Heon

    Allergy, asthma & immunology research

    2021  Volume 13, Issue 2, Page(s) 173–176

    Language English
    Publishing date 2021-01-21
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2545725-1
    ISSN 2092-7363 ; 2092-7355
    ISSN (online) 2092-7363
    ISSN 2092-7355
    DOI 10.4168/aair.2021.13.2.173
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  3. Article: Active Pharmacovigilance of Drug-Induced Liver Injury Using Electronic Health Records.

    Kim, Sang Heon

    Allergy, asthma & immunology research

    2020  Volume 12, Issue 3, Page(s) 378–380

    Language English
    Publishing date 2020-03-05
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2545725-1
    ISSN 2092-7363 ; 2092-7355
    ISSN (online) 2092-7363
    ISSN 2092-7355
    DOI 10.4168/aair.2020.12.3.378
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  4. Article ; Online: COVID-19 Vaccine-Induced Multisystem Inflammatory Syndrome With Polyserositis Detected by FDG PET/CT: Reply.

    Lee, Soo Jin / Kim, Sang-Heon

    Clinical nuclear medicine

    2022  Volume 47, Issue 11, Page(s) e723

    MeSH term(s) COVID-19 ; COVID-19 Vaccines/adverse effects ; Fluorodeoxyglucose F18 ; Humans ; Inflammation ; Positron Emission Tomography Computed Tomography ; Positron-Emission Tomography ; Systemic Inflammatory Response Syndrome
    Chemical Substances COVID-19 Vaccines ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2022-04-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197628-x
    ISSN 1536-0229 ; 0363-9762
    ISSN (online) 1536-0229
    ISSN 0363-9762
    DOI 10.1097/RLU.0000000000004247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1276: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Risk of Pneumonia Associated With the Use of Inhaled Corticosteroids in Asthma.

    Kim, Sang Heon

    Allergy, asthma & immunology research

    2019  Volume 11, Issue 6, Page(s) 760–762

    Language English
    Publishing date 2019-09-24
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2545725-1
    ISSN 2092-7363 ; 2092-7355
    ISSN (online) 2092-7363
    ISSN 2092-7355
    DOI 10.4168/aair.2019.11.6.760
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  6. Article ; Online: Reply to "New-onset asthma development in adults after COVID-19 disease".

    Lee, Hyun / Kim, Bo-Guen / Kim, Sang-Heon

    The journal of allergy and clinical immunology. In practice

    2023  Volume 11, Issue 12, Page(s) 3820–3821

    Language English
    Publishing date 2023-12-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.10.002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7086: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Investigating fatty liver disease-associated adverse outcome pathways of perfluorooctane sulfonate using a systems toxicology approach.

    Kim, Moosoo / Kim, Sang Heon / Choi, Jun Yeong / Park, Yong Joo

    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

    2023  Volume 176, Page(s) 113781

    Abstract: Adverse outcome pathway (AOP) frameworks help elucidate toxic mechanisms and support chemical regulation. AOPs link a molecular initiating event (MIE), key events (KEs), and an adverse outcome by key event relationships (KERs), which assess the ... ...

    Abstract Adverse outcome pathway (AOP) frameworks help elucidate toxic mechanisms and support chemical regulation. AOPs link a molecular initiating event (MIE), key events (KEs), and an adverse outcome by key event relationships (KERs), which assess the biological plausibility, essentiality, and empirical evidence involved. Perfluorooctane sulfonate (PFOS), a hazardous poly-fluoroalkyl substance, demonstrates hepatotoxicity in rodents. PFOS may induce fatty liver disease (FLD) in humans; however, the underlying mechanism remains unclear. In this study, we evaluated the toxic mechanisms of PFOS-associated FLD by developing an AOP using publicly available data. We identified MIE and KEs by performing GO enrichment analysis on PFOS- and FLD-associated target genes collected from public databases. The MIEs and KEs were then prioritized by PFOS-gene-phenotype-FLD networks, AOP-helpFinder, and KEGG pathway analyses. Following a comprehensive literature review, an AOP was then developed. Finally, six KEs for the AOP of FLD were identified. This AOP indicated that toxicological processes initiated by SIRT1 inhibition led to SREBP-1c activation, de novo fatty acid synthesis, and fatty acid and triglyceride accumulation, culminating in liver steatosis. Our study provides insights into the toxic mechanism of PFOS-induced FLD and suggests approaches to assessing the risk of toxic chemicals.
    MeSH term(s) Humans ; Adverse Outcome Pathways ; Databases, Factual ; Non-alcoholic Fatty Liver Disease ; Phenotype ; Risk Assessment
    Chemical Substances perfluorooctane (6P60ZBK0QL) ; perfluorooctane sulfonic acid (9H2MAI21CL)
    Language English
    Publishing date 2023-04-12
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2023.113781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 529: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap After the Third Dose of BNT162b2 mRNA COVID-19 Vaccination and Literature Review.

    Jue, Mihn-Sook / Joh, Hae Chang / Kim, Sang Heon / Ko, Joo Yeon

    Dermatitis : contact, atopic, occupational, drug

    2023  Volume 34, Issue 2, Page(s) 158–159

    MeSH term(s) Humans ; Stevens-Johnson Syndrome/etiology ; BNT162 Vaccine ; COVID-19 Vaccines/adverse effects ; COVID-19/prevention & control ; Anti-Bacterial Agents
    Chemical Substances BNT162 Vaccine ; COVID-19 Vaccines ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Review ; Letter ; Comment
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1089/derm.2022.29003.msj
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3680: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Vas Deferens Abscess Rupture: A Case Report.

    Pak, Beom Kyun / Kang, Dong Min / Kim, Sang Heon

    Journal of the Belgian Society of Radiology

    2022  Volume 106, Issue 1, Page(s) 70

    Abstract: A vas deferens abscess is a very rare complication of acute vasitis and lower urinary tract infection. A case of vas deferens rupture due to an abscess with severe pelvic inflammation requiring surgical drainage is reported. ...

    Abstract A vas deferens abscess is a very rare complication of acute vasitis and lower urinary tract infection. A case of vas deferens rupture due to an abscess with severe pelvic inflammation requiring surgical drainage is reported.
    Language English
    Publishing date 2022-07-27
    Publishing country England
    Document type Case Reports
    ZDB-ID 2834839-4
    ISSN 2514-8281
    ISSN 2514-8281
    DOI 10.5334/jbsr.2840
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  10. Article ; Online: Investigating fatty liver disease-associated adverse outcome pathways of perfluorooctane sulfonate using a systems toxicology approach

    Kim, Moosoo / Kim, Sang Heon / Choi, Jun Yeong / Park, Yong Joo

    Food and Chemical Toxicology. 2023 Apr. 12, p.113781-

    2023  , Page(s) 113781–

    Abstract: Adverse outcome pathway (AOP) frameworks help elucidate toxic mechanisms and support chemical regulation. AOPs link a molecular initiating event (MIE), key events (KEs), and an adverse outcome by key event relationships (KERs), which assess the ... ...

    Abstract Adverse outcome pathway (AOP) frameworks help elucidate toxic mechanisms and support chemical regulation. AOPs link a molecular initiating event (MIE), key events (KEs), and an adverse outcome by key event relationships (KERs), which assess the biological plausibility, essentiality, and empirical evidence involved. Perfluorooctane sulfonate (PFOS), a hazardous poly-fluoroalkyl substance, demonstrates hepatotoxicity in rodents. PFOS may induce fatty liver disease (FLD) in humans; however, the underlying mechanism remains unclear. In this study, we evaluated the toxic mechanisms of PFOS-associated FLD by developing an AOP using publicly available data. We identified MIE and KEs by performing GO enrichment analysis on PFOS- and FLD-associated target genes collected from public databases. The MIEs and KEs were then prioritized by PFOS–gene–phenotype–FLD networks, AOP-helpFinder, and KEGG pathway analyses. Following a comprehensive literature review, an AOP was then developed. Finally, six KEs for the AOP of FLD were identified. This AOP indicated that toxicological processes initiated by SIRT1 inhibition led to SREBP-1c activation, de novo fatty acid synthesis, and fatty acid and triglyceride accumulation, culminating in liver steatosis. Our study provides insights into the toxic mechanism of PFOS-induced FLD and suggests approaches to assessing the risk of toxic chemicals.
    Keywords adverse outcome pathways ; fatty acids ; fatty liver ; hepatotoxicity ; perfluorooctane sulfonic acid ; toxicology ; triacylglycerols ; Adverse outcome pathway ; Perfluorooctane sulfonate ; Fatty liver disease ; SIRT1 ; AO ; AOP ; CTD ; FLD ; GO ; KE ; KEGG ; KER ; MIE ; OECD ; PFOS ; QSAR ; SREBP
    Language English
    Dates of publication 2023-0412
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 782617-5
    ISSN 1873-6351 ; 0278-6915
    ISSN (online) 1873-6351
    ISSN 0278-6915
    DOI 10.1016/j.fct.2023.113781
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4035: Show issues

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