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  1. Article: Asymptomatic Bacteriuria in Pregnancy Complicated by Pyelonephritis Requiring Nephrectomy.

    Kim, Sharon J / Parikh, Pavan / King, Amanda N / Marnach, Mary L

    Case reports in obstetrics and gynecology

    2018  Volume 2018, Page(s) 8924823

    Abstract: Routine prenatal care in the United States includes screening for asymptomatic bacteriuria (ASB), which occurs in 2 to 7 percent of pregnant women and can cause urinary tract infection and pyelonephritis. We present the case of a pregnant woman affected ... ...

    Abstract Routine prenatal care in the United States includes screening for asymptomatic bacteriuria (ASB), which occurs in 2 to 7 percent of pregnant women and can cause urinary tract infection and pyelonephritis. We present the case of a pregnant woman affected by multidrug resistant Klebsiella induced ASB during her prenatal screen, which was untreated due to a repeat urine culture showing mixed flora; subsequently, the patient's postpartum course was complicated by pyelonephritis and perinephric abscess, concluding in a radical nephrectomy. Current recommendations are to treat ASB after two consecutive voided urine cultures showing the same bacterial strain in quantitative counts of =/> 10(5) colony forming units (cfu)/mL or a single-catheterized specimen with quantitative count of =/> 10(2) cfu/mL. For women with ASB in their prenatal screen or other high risk factors, consideration should be given to testing urine cultures every trimester until the completion of pregnancy to prevent the complications of persistent bacteriuria.
    Language English
    Publishing date 2018-09-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627654-9
    ISSN 2090-6692 ; 2090-6684
    ISSN (online) 2090-6692
    ISSN 2090-6684
    DOI 10.1155/2018/8924823
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Retrospective 15-Year Review of Anal Cytology Screening in Women at Mayo Clinic Rochester, Minnesota.

    Marnach, Mary L / Larish, Alyssa M / Kim, Sharon J / Mara, Kristin C / Henry, Michael R / Chantigian, Paula D M

    Journal of lower genital tract disease

    2020  Volume 24, Issue 3, Page(s) 238–242

    Abstract: Objectives: Anal cytology is a modality for anal cancer screening in high-risk women. In this retrospective study, we review risk factors associated with abnormal anal cytology and unsatisfactory anal cytology rates, and correlate findings of cytology ... ...

    Abstract Objectives: Anal cytology is a modality for anal cancer screening in high-risk women. In this retrospective study, we review risk factors associated with abnormal anal cytology and unsatisfactory anal cytology rates, and correlate findings of cytology with histological results.
    Methods: A retrospective cohort study of anal cytology screening in women at Mayo Clinic in Rochester, Minnesota from 2002 to 2018 was conducted.
    Results: Three hundred fifty-seven women had a total of 592 anal cytologies performed. Three hundred seventeen women had screening anal cytology, whereas 40 women had anal cytology for surveillance given a history of anal intraepithelial neoplasia (AIN) or anal cancer. An unsatisfactory anal cytology result was found in 14.7%. Risk factors, type of follow-up, and correlation with histologic specimens were also reviewed. Histologic finding of AIN 2/3 correlated with abnormal anal cytology 84% of the time in this cohort.
    Conclusions: High-risk women should be screened on a periodic basis for anal cancer. Anal cytology is one possible modality that can be used. Further insight into AIN progression, regression, recurrence, and outcome after treatment will help direct future screening recommendations.
    MeSH term(s) Adult ; Anal Canal/pathology ; Anus Neoplasms/diagnosis ; Anus Neoplasms/pathology ; Carcinoma in Situ/pathology ; Cytological Techniques ; Early Detection of Cancer/statistics & numerical data ; Female ; Humans ; Middle Aged ; Retrospective Studies ; Risk Factors
    Language English
    Publishing date 2020-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2041332-4
    ISSN 1526-0976 ; 1089-2591
    ISSN (online) 1526-0976
    ISSN 1089-2591
    DOI 10.1097/LGT.0000000000000535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5466: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Ventricular fibrillation after elective surgery in an adolescent with long QT syndrome.

    Kim, Sharon J / Pundi, Kavitha N / Bos, J Martijn / Ackerman, Michael J

    BMJ case reports

    2015  Volume 2015

    Abstract: Congenital long QT syndrome (LQTS) is a potentially lethal but highly treatable channelopathy. Along with multiple risk reduction measures, a recommendation for left sympathetic cardiac denervation therapy and/or implantable cardioverter defibrillator is ...

    Abstract Congenital long QT syndrome (LQTS) is a potentially lethal but highly treatable channelopathy. Along with multiple risk reduction measures, a recommendation for left sympathetic cardiac denervation therapy and/or implantable cardioverter defibrillator is made for higher risk patients. Despite its relatively common incidence in paediatric patients, there are no formal recommendations regarding perioperative management and discharge criteria for LQTS patients undergoing ambulatory surgery. This report describes a 17-year-old girl, diagnosed with congenital LQTS at 9 years of age, who had an episode of ventricular fibrillation the day after elective ear, nose and throat surgery. Despite several risk factors, she had a same-day dismissal, was not adequately monitored postoperatively and her cardiologists were not notified of her procedure. For the high-risk LQTS patient, we recommend monitoring of perioperative electrolytes and rhythm, postoperative ECG, adequate β-blockade therapy, avoidance of particular pharmacological agents, consideration of overnight observation and communication with the patient's cardiologist prior to procedure, and at discharge.
    MeSH term(s) Adolescent ; Ambulatory Surgical Procedures/adverse effects ; Defibrillators, Implantable ; Elective Surgical Procedures/adverse effects ; Female ; Humans ; Long QT Syndrome/complications ; Long QT Syndrome/therapy ; Monitoring, Intraoperative ; Nasal Septum/abnormalities ; Nasal Septum/surgery ; Risk Factors ; Ventricular Fibrillation/etiology
    Language English
    Publishing date 2015-11-26
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-212365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Surgical Treatment and Outcomes of Patients With Extramammary Paget Disease: A Cohort Study.

    Kim, Sharon J / Thompson, Agnieszka K / Zubair, Adeel S / Otley, Clark C / Arpey, Christopher J / Baum, Christian L / Roenigk, Randall K / Lohse, Christine M / Brewer, Jerry D

    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.

    2017  Volume 43, Issue 5, Page(s) 708–714

    Abstract: Background: Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma occurring mainly in the anogenital region. Traditional management with wide local excision has shown high recurrence rates, thus Mohs micrographic surgery (MMS) has ... ...

    Abstract Background: Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma occurring mainly in the anogenital region. Traditional management with wide local excision has shown high recurrence rates, thus Mohs micrographic surgery (MMS) has emerged as a promising treatment option.
    Objective: To compare long-term outcomes after treatment with MMS or excision for primary EMPD.
    Methods and materials: Retrospective cohort review was conducted for 207 patients with EMPD treated at Mayo Clinic in Rochester, MN, between 1961 and 2012.
    Results: Of the 25 patients treated with MMS, 19 primary tumors were included for outcome analysis, with an estimated 5-year recurrence-free survival rate of 91% (95% confidence interval [CI], 75-100) using Kaplan-Meier curve analysis. Of 158 patients treated with local excision, 124 were included for the analysis, with an estimated 5-year recurrence-free survival rate of 66% (95% CI, 56-78). The hazard ratio (HR) for association of treatment was 0.4 (95% CI, 0.10-1.65; p = .20). Estimated 5-year overall survival rates were 79% for MMS (95% CI, 61-100) and 68% for excision (95% CI, 59-78) (HR, 1.39 [95% CI, 0.69-2.82]; p = .36).
    Conclusion: Although treatment of primary EMPD with MMS versus excision did not show statistical difference, MMS demonstrated favorable long-term outcomes and was associated with a higher recurrence-free survival rate.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Disease-Free Survival ; Female ; Genital Neoplasms, Male/surgery ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Mohs Surgery ; Neoplasm Recurrence, Local ; Paget Disease, Extramammary/mortality ; Paget Disease, Extramammary/surgery ; Retrospective Studies ; Scrotum/surgery ; Treatment Outcome ; Vulvar Neoplasms/surgery
    Language English
    Publishing date 2017-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1227586-4
    ISSN 1524-4725 ; 1076-0512
    ISSN (online) 1524-4725
    ISSN 1076-0512
    DOI 10.1097/DSS.0000000000001051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1212: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Using Bundled Interventions to Reduce Surgical Site Infection After Major Gynecologic Cancer Surgery.

    Johnson, Megan P / Kim, Sharon J / Langstraat, Carrie L / Jain, Sneha / Habermann, Elizabeth B / Wentink, Jean E / Grubbs, Pamela L / Nehring, Sharon A / Weaver, Amy L / McGree, Michaela E / Cima, Robert R / Dowdy, Sean C / Bakkum-Gamez, Jamie N

    Obstetrics and gynecology

    2015  Volume 127, Issue 6, Page(s) 1135–1144

    Abstract: Objective: To investigate whether implementing a bundle, defined as a set of evidence-based practices performed collectively, can reduce 30-day surgical site infections.: Methods: Baseline surgical site infection rates were determined retrospectively ...

    Abstract Objective: To investigate whether implementing a bundle, defined as a set of evidence-based practices performed collectively, can reduce 30-day surgical site infections.
    Methods: Baseline surgical site infection rates were determined retrospectively for cases of open uterine cancer, ovarian cancer without bowel resection, and ovarian cancer with bowel resection between January 1, 2010, and December 31, 2012, at an academic center. A perioperative bundle was prospectively implemented during the intervention period (August 1, 2013, to September 30, 2014). Prior established elements were: patient education, 4% chlorhexidine gluconate shower before surgery, antibiotic administration, 2% chlorhexidine gluconate and 70% isopropyl alcohol coverage of incisional area, and cefazolin redosing 3-4 hours after incision. New elements initiated were: sterile closing tray and staff glove change for fascia and skin closure, dressing removal at 24-48 hours, dismissal with 4% chlorhexidine gluconate, and follow-up nursing phone call. Surgical site infection rates were examined using control charts, compared between periods using χ or Fisher exact test, and validated against the American College of Surgeons National Surgical Quality Improvement Program decile ranking.
    Results: The overall 30-day surgical site infection rate was 38 of 635 (6.0%) among all cases in the preintervention period, with 11 superficial (1.7%), two deep (0.3%), and 25 organ or space infections (3.9%). In the intervention period, the overall rate was 2 of 190 (1.1%), with two organ or space infections (1.1%). Overall, the relative risk reduction in surgical site infection was 82.4% (P=.01). The surgical site infection relative risk reduction was 77.6% among ovarian cancer with bowel resection, 79.3% among ovarian cancer without bowel resection, and 100% among uterine cancer. The American College of Surgeons National Surgical Quality Improvement Program decile ranking improved from the 10th decile to first decile; risk-adjusted odds ratio for surgical site infection decreased from 1.6 (95% confidence interval 1.0-2.6) to 0.6 (0.3-1.1).
    Conclusion: Implementation of an evidence-based surgical site infection reduction bundle was associated with substantial reductions in surgical site infection in high-risk cancer procedures.
    MeSH term(s) Evidence-Based Medicine ; Female ; Genital Neoplasms, Female/surgery ; Humans ; Interdisciplinary Communication ; Middle Aged ; Minnesota ; Outcome and Process Assessment, Health Care ; Patient Care Bundles/standards ; Prospective Studies ; Quality Improvement ; Surgical Wound Infection/prevention & control
    Language English
    Publishing date 2015-12-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207330-4
    ISSN 1873-233X ; 0029-7844
    ISSN (online) 1873-233X
    ISSN 0029-7844
    DOI 10.1097/AOG.0000000000001449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Um I Zs.230: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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