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  1. Book ; Online: CFD Based Researches and Applications for Fluid Machinery and Fluid Device

    Kim, Jin-Hyuk / Kim, Sung-Min / Choi, Minsuk / Tan, Lei / Huang, Bin / Pei, Ji

    2021  

    Keywords Technology: general issues ; centrifugal fan ; noise characteristics ; power consumption ; negative pressure ; sound pressure ; mechanical seal ; dynamic characteristics ; extrusion fault ; numerical simulation ; sealing performance ; fluent ; inducer ; step casing ; varying pitch ; cavitating flow and instabilities ; partial similarity principle ; flow similarity ; stability improvement ; multi-condition optimization ; cavitation performance ; artificial neural networks (ANN) ; net positive suction head (NPSH) ; double suction ; cascade ; aerodynamic ; parameterization ; plane cascade design ; incidence angle ; PSO-MVFSA ; optimization ; two-vane pump ; Computational Fluid Dynamics (CFD) ; Reynolds-averaged Navier-Stokes (RANS) ; machine learning ; energy recovery ; pump as turbine ; vortex ; hydraulic losses ; pressure fluctuation ; transient characteristics ; centrifugal pump ; startup period ; solar air heater ; ribs ; Nusselt number ; friction factor ; Reynolds-averaged Navier-Stokes equations ; thrust coefficient ; power coefficient ; figure of merit ; frozen rotor ; UAV ; octorotor SUAV ; aerodynamic performance ; rotor spacing ; hover ; CFD ; vortices distribution ; shape optimization ; Francis turbine ; fixed flow passage ; flow uniformity ; blade outlet angle ; Sirocco fan ; URANS ; volute tongue radius ; internal flow ; noise ; film cooling ; large eddy simulation ; triple holes ; blowing ratio ; adiabatic film-cooling effectiveness ; proper orthogonal decomposition ; axial compressor ; tip clearance ; flow field ; clearance ; flow function ; gas turbine ; leakage ; pressure ratio ; stepped labyrinth seal ; axial-flow pump ; root clearance radius ; computational fluid dynamics ; entropy production ; energy dissipation ; vortex pump ; lateral cavity ; open-design ; spiral flow ; reactor coolant pump (RCP) ; waviness ; leakage rate ; liquid film ; axial fan ; reversible ; jet ; design ; thrust ; energy characteristics ; mixing ; pitched blade turbine ; impeller ; inverse design method ; matching optimization ; diffuser ; small hydropower ; tubular turbine ; fish farm ; performance test ; design factors ; optimum model ; the mixed free-surface-pressurized flow ; characteristic implicit method ; relative roughness ; vent holes ; optimization control ; microchannel heat sink ; wavy microchannel ; groove ; heat transfer performance ; laminar flow ; multi-objective optimization ; LHS ; full factorial methods ; pump-turbine ; dynamic stress ; start-up process ; vortex generator (VG) ; computational fluid dynamics (CFD) ; cell-set model ; RANS ; LES ; multistage centrifugal pump ; double-suction impeller ; twin-volute ; inducer-type guide vane ; trailing edge flap (TEF) ; trailing edge flap with Micro-Tab ; deflection angle of the flap (αF) ; n/a
    Size 1 electronic resource (539 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021291524
    ISBN 9783036518152 ; 3036518150
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Prediction of optimum alkaline hydrolysis conditions for imparting superhydrophobicity to large-area fabrics using three-dimensional modeling

    Cho, Yoonkyung / Kim, Sungmin

    Textile Research Journal. 2023 Aug., v. 93, no. 15-16 p.3703-3716

    2023  

    Abstract: This study proposes a fabric-specific alkaline hydrolysis method to impart stable water repellency to large-area polyester fabrics, regardless of yarn type or weave pattern. The geometries of 120 virtual fabrics with varying yarn properties, weave ... ...

    Abstract This study proposes a fabric-specific alkaline hydrolysis method to impart stable water repellency to large-area polyester fabrics, regardless of yarn type or weave pattern. The geometries of 120 virtual fabrics with varying yarn properties, weave patterns, and weave densities are modeled, and their surface-etching efficiency and superhydrophobicity are predicted. While the alkaline hydrolysis-derived nano-structuring efficiencies of fabrics are predicted based on the Kallay and Grancaric model (1990) with changes to reflect the fiber volume fraction F as a major variable for fabric structures. For predicting superhydrophobicity, the fabric meso-structure contact angle is calculated based on the Michielsen and Lee model (2007); the fixed yarn distance used in the original model is replaced by the simulated inter-yarn porosity P to exclude error caused by structural variability. The final virtual fabric contact angle is predicted reflecting the effect of nano-roughness, which is validated by comparing the predicted contact angle with a physical sample having identical geometries. The contact angle of any fabric can be predicted using structural simulation, given the alkaline treatment conditions are adjusted according to the unique geometry of each fabric to express superhydrophobicity. Moreover, even for samples with low predictive contact angles, superhydrophobicity can be achieved by maximizing the effect of the nanostructure through strong alkaline treatment. An ISO 5 water repellency is achieved for all large-area polyester fabrics.
    Keywords alkali treatment ; alkaline hydrolysis ; contact angle ; fabrics ; geometry ; hydrophobicity ; models ; nanomaterials ; polyesters ; porosity ; prediction ; research ; efficiency prediction ; fabric geometry modeling ; nanoscale structuring ; superhydrophobic fabric
    Language English
    Dates of publication 2023-08
    Size p. 3703-3716.
    Publishing place SAGE Publications
    Document type Article ; Online
    ZDB-ID 2209596-2
    ISSN 1746-7748 ; 0040-5175
    ISSN (online) 1746-7748
    ISSN 0040-5175
    DOI 10.1177/00405175231165334
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: MMP-9-dependent proteolysis of the histone H3 N-terminal tail: a critical epigenetic step in driving oncogenic transcription and colon tumorigenesis.

    Shin, Yonghwan / Kim, Sungmin / Liang, Gangning / An, Woojin

    Molecular oncology

    2024  

    Abstract: Matrix metalloproteinase 9 (MMP-9) is a member of the MMP family and has been recently identified as a nuclear protease capable of clipping histone H3 N-terminal tails (H3NT). This MMP-9-dependent H3NT proteolysis is critical for establishing an active ... ...

    Abstract Matrix metalloproteinase 9 (MMP-9) is a member of the MMP family and has been recently identified as a nuclear protease capable of clipping histone H3 N-terminal tails (H3NT). This MMP-9-dependent H3NT proteolysis is critical for establishing an active state of gene transcription during osteoclast differentiation and melanoma development. However, whether H3NT cleavage by MMP-9 plays a similar role in other cellular events has not been explored. Here, we dissect the functional contribution of MMP-9-dependent H3NT clipping to colonic tumorigenesis by using a combination of genome-wide transcriptome data, ChIP/ChIPac-qPCR, CRISPR/dCas9 gene-targeting system, and in vivo xenograft models. We show that MMP-9 is overexpressed in colon cancer cells and catalyzes H3NT proteolysis to drive transcriptional activation of growth stimulatory genes. Our studies using knockdown and inhibition approaches clearly indicate that MMP-9 mediates transcriptional activation and promotes colonic tumorigenesis in a manner dependent on its protease activity toward H3NT. Remarkably, artificial H3NT proteolysis at target gene promoters with dCAS9-MMP-9 is sufficient for establishing their transcriptional competence in colon cancer cells, underscoring the importance of MMP-9-dependent H3NT proteolysis per se in the transactivation process. Our data establish new functions and mechanisms for MMP-9 in driving the oncogenic transcription program in colon cancer through H3NT proteolysis, and demonstrate how this epigenetic pathway can be exploited as a potential therapeutic target for cancer treatment.
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2415106-3
    ISSN 1878-0261 ; 1574-7891
    ISSN (online) 1878-0261
    ISSN 1574-7891
    DOI 10.1002/1878-0261.13652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Comparison of macular changes according to the etiology of optic neuritis: a cross-sectional study.

    Moon, Yeji / Kim, Sung-Min / Jung, Jae Ho

    International journal of ophthalmology

    2024  Volume 17, Issue 4, Page(s) 686–692

    Abstract: Aim: To compare the macular structure including foveal thickness among patients with optic neuritis (ON) according to the etiology and to investigate the possible correlation between structural and visual outcomes.: Methods: In this retrospective ... ...

    Abstract Aim: To compare the macular structure including foveal thickness among patients with optic neuritis (ON) according to the etiology and to investigate the possible correlation between structural and visual outcomes.
    Methods: In this retrospective cross-sectional study, the clinical data of patients with aquaporin-4 immunoglobulin G-related ON (AQP4 group, 40 eyes), myelin oligodendrocyte glycoprotein IgG-related ON (MOG group, 31 eyes), and multiple sclerosis-related ON (MS group, 24 eyes) were obtained. The retinal thickness of the foveal, parafoveal and perifoveal regions were measured. Visual acuity (VA), visual field index and mean deviation were measured as visual outcomes.
    Results: The AQP4 group showed a significantly thinner fovea (226.4±13.4 µm) relative to the MOG (236.8±14.0 µm,
    Conclusion: The significant thinning in the fovea and parafoveal areas in the AQP4 group compared to the MOG and MS groups are found. Additionally, macular changes in AQP4-ON show a significant correlation with VA. The results provide the possibility that retinal structural damage could reflect functional damage in AQP4-ON, distinct from MOG-ON and MS-ON.
    Language English
    Publishing date 2024-04-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2663246-9
    ISSN 2227-4898 ; 2222-3959
    ISSN (online) 2227-4898
    ISSN 2222-3959
    DOI 10.18240/ijo.2024.04.12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Diabetes and Viral Diseases

    Kim, Sungmin

    J Korean Diabetes

    Abstract: Patients with diabetes are more susceptible to viral diseases, which are more likely to progress to severe cases in such patients Diabetes and hyperglycemia have been reported to be major risk factors and poor prognostic factors for 2019 flu, severe ... ...

    Abstract Patients with diabetes are more susceptible to viral diseases, which are more likely to progress to severe cases in such patients Diabetes and hyperglycemia have been reported to be major risk factors and poor prognostic factors for 2019 flu, severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and the currently ongoing coronavirus disease-2019 (COVID-19) However, it is not clear yet whether diabetes itself leads to higher risk and becomes a poor prognostic factor for viral diseases or if the real main factors are actually cardiovascular and renal complications that often accompany diabetes On the other hand, viral diseases have frequently been suggested to be one cause or a contributing factor to develop diabetes Two typical examples are the association between enteroviruses such as Coxsackie B virus and type 1 diabetes and the relationship between hepatitis C virus and type 2 diabetes Recently, there has been research on the potentiality of changes in the intestinal microflora being a cause for diabetes, and there is evidence to suggest that intestinal virome affects intestinal microbiota There has also been a claim that extracellular vesicles secreted by
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #678320
    Database COVID19

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  6. Article: Automated Textile Circuit Generation using Machine Vision and Embroidery Technique

    Ahn, Jiseon / Kim, Sungmin

    Textile research journal. 2022 June, v. 92, no. 11-12

    2022  

    Abstract: An automated textile circuit generation method was developed using machine vision and embroidery technique. For this, an image acquisition device was designed to capture the physical layout image of electronic devices on the fabric. A series of image ... ...

    Abstract An automated textile circuit generation method was developed using machine vision and embroidery technique. For this, an image acquisition device was designed to capture the physical layout image of electronic devices on the fabric. A series of image analysis algorithms were developed to calibrate the image and recognize the type, location, and orientation of each device from the image. Dedicated computer-aided design software was developed that can design a circuit and modify it according to the actual device layout on the fabric. It can also convert the circuit elements such as conductive path and insulation layer into data for a computerized embroidery machine. An example circuit consisting of seven electronic devices was designed and repeatedly produced to verify the developed method. The method has shown promising results.
    Keywords automation ; computer software ; computer vision ; computer-aided design ; fabrics ; image analysis ; insulating materials ; research
    Language English
    Dates of publication 2022-06
    Size p. 1977-1986.
    Publishing place SAGE Publications
    Document type Article
    ZDB-ID 2209596-2
    ISSN 1746-7748 ; 0040-5175
    ISSN (online) 1746-7748
    ISSN 0040-5175
    DOI 10.1177/00405175221075062
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Examining the joint coordination during dynamic balance learning using vector coding and statistical parametric mapping analyses.

    Kim, Sungmin / Qu, Feng / Wang, Yi / Lam, Wing-Kai

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1724

    Abstract: We aimed to examine the changes in balance performance, kinematic variables, and joint coordination of the lower extremities during the Y-balance learning task. Twenty female university students completed five consecutive blocks of Y-balance learning ... ...

    Abstract We aimed to examine the changes in balance performance, kinematic variables, and joint coordination of the lower extremities during the Y-balance learning task. Twenty female university students completed five consecutive blocks of Y-balance learning from days 3 to 7 (135 trials). Pre-tests and tests were performed on days 1 and 9. Maximum reach distance, peak joint angle, and joint coordination in the anterior (AL), posterolateral (PL), and posteromedial (PM) directions were measured to determine the efficacy of Y-balance performance. A repeated measures ANOVA was performed for the maximum reach distance across learning blocks to confirm whether learning had occurred. Our results indicated that the maximum reach distance on day 5 was longer than that on other learning days. The maximum reach distance significantly increased in the PL and PM directions after learning. The hip flexion (PL/PM), abduction (PM), internal rotation (PM), and external rotation (PL) angles increased after learning. The knee joint flexion angle increased in both AL and PL directions. Only the ankle dorsiflexion angle increased in the AL direction. Joint coordination indicated that the knee and hip joints performed simultaneously during internal rotation. Ankle-knee joint coordination was performed using dorsiflexion and flexion strategies. Statistical parametric mapping analysis indicated significant differences in the ankle sagittal plane in the AL direction, hip horizontal and hip/knee sagittal planes in the PL direction, and hip/knee sagittal and hip frontal/horizontal planes in the PM direction. These data suggest that the dynamic balance ability of the novice participants improved in relation to changes in coordination patterns after learning. The results of this study can be applied to other populations to improve their dynamic balance and prevent fall injuries.
    MeSH term(s) Humans ; Female ; Lower Extremity ; Knee Joint ; Movement ; Ankle Joint ; Range of Motion, Articular ; Biomechanical Phenomena ; Hip Joint
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44216-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Novel Use of a Fibular Strut Allograft with Fibular Head in an Elderly Patient with Proximal Humeral Fracture and Severe Metaphyseal Comminution: An Alternative to Shoulder Arthroplasty.

    Lim, Jun-Hyuk / Ahn, Yeong-Seub / Kim, Sungmin / Kim, Myung-Sun

    Journal of clinical medicine

    2024  Volume 13, Issue 8

    Abstract: Treatment of a comminuted proximal humerus fracture (PHF) in elderly patients with severe osteoporosis is challenging, often leading to arthroplasty (such as hemiarthroplasty or reverse shoulder arthroplasty) as the treatment of choice. However, ... ...

    Abstract Treatment of a comminuted proximal humerus fracture (PHF) in elderly patients with severe osteoporosis is challenging, often leading to arthroplasty (such as hemiarthroplasty or reverse shoulder arthroplasty) as the treatment of choice. However, arthroplasty does not always guarantee favorable outcomes. In contrast, the use of intramedullary fibular strut allografts provides additional reduction stability during locking plate fixation; however, to our knowledge, there is limited literature on the use of fibular strut allografts, including the fibular head. Here we aim to report the advantages of using a fibular strut containing the fibular head in severe osteoporotic PHFs. We present the case of an 88-year-old female patient with severe osteoporosis diagnosed with a left PHF accompanied by severe metaphyseal comminution following a fall from a chair. Rather than shoulder arthroplasty, we performed osteosynthesis using a fibular strut allograft containing the fibular head. At the one-year follow-up after surgery, we observed excellent bony union and a favorable functional outcome without major complications, such as reduction loss. The novel use of a fibular strut allograft containing the fibular head could be promising for PHFs with severe metaphyseal comminution, potentially avoiding the need for arthroplasty.
    Language English
    Publishing date 2024-04-11
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13082200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The effects of knee ligament load using simulated hip abductor and hamstring muscle strengthening during cutting maneuver.

    Kim, Sungmin / Han, Sanghyuk / Kim, Seongyong / Moon, Jeheon

    Medicine

    2023  Volume 102, Issue 46, Page(s) e35742

    Abstract: Background: This study aimed to analyze knee ligament of load and joint moment to simulate the strengthening of the hip abductor and hamstring muscles using musculoskeletal modeling, thereby contributing to decrease of knee ligament load.: Methods: ... ...

    Abstract Background: This study aimed to analyze knee ligament of load and joint moment to simulate the strengthening of the hip abductor and hamstring muscles using musculoskeletal modeling, thereby contributing to decrease of knee ligament load.
    Methods: Forty participants (age: 21.85 ± 1.90 years; height: 1.76 ± 0.06 m; body mass: 68.5 ± 7.06 kg) were instructed to run at 4.5 ± 0.2 m/s from a 5 m distance posterior to the force plate, land their feet on the force plate, and perform the cutting maneuver on the left. In the musculoskeletal modeling, the hip abductor and hamstring muscles were targeted to construct a model with a 30% increase in the contraction force of the hip abductor, hamstring, and both 2 muscles. The variables were the ligament force and knee joint moment. One-way repeated measure ANOVA and Bonferroni test were used to compare the abductor/hamstring, abductor, hamstring and control models.
    Results: There were significant differences in anterior bundle of the anterior cruciate ligament (ACL) (P = .001), inferior bundle of the superficial layer of the medial collateral ligament (MCL) (P = .016), and posterior bundle of the superficial layer of the MCL (P = .022) force. The post hoc showed that the hamstring model had lower anterior bundle of the ACL and inferior bundle of the superficial layer of the MCL than the abductor/hamstring and abductor models (P < .05) and lower posterior bundle of the superficial layer of the MCL than the abductor and control models (P < .05). There was a significant difference in the adduction (P = .028) and internal rotation moments (P = .014). The post hoc showed that both moments were lower in the hamstring model than in the other models (P < .05).
    Conclusions: The hamstring strengthening may contribute significantly to preventing ACL or MCL injury by reducing knee ligament load.
    MeSH term(s) Humans ; Young Adult ; Adult ; Hamstring Muscles ; Biomechanical Phenomena ; Knee Joint/physiology ; Anterior Cruciate Ligament ; Anterior Cruciate Ligament Injuries/surgery
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000035742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Feasibility study for the automatic surgical planning method based on statistical model.

    Nguyen, Hang Phuong / Lee, Hyun-Joo / Kim, Sungmin

    Journal of orthopaedic surgery and research

    2023  Volume 18, Issue 1, Page(s) 398

    Abstract: Purpose: In this study, we proposed establishing an automatic computer-assisted surgical planning approach based on average population models.: Methods: We built the average population models from humerus datasets using the Advanced Normalization ... ...

    Abstract Purpose: In this study, we proposed establishing an automatic computer-assisted surgical planning approach based on average population models.
    Methods: We built the average population models from humerus datasets using the Advanced Normalization Toolkits (ANTs) and Shapeworks. Experiments include (1) evaluation of the average population models before surgical planning and (2) validation of the average population models in the context of predicting clinical landmarks on the humerus from the new dataset that was not involved in the process of building the average population model. The evaluation experiment consists of explained variation and distance model. The validation experiment calculated the root-mean-square error (RMSE) between the expert-determined clinical ground truths and the landmarks transferred from the average population model to the new dataset. The evaluation results and validation results when using the templates built from ANTs were compared to when using the mean shape generated from Shapeworks.
    Results: The average population models predicted clinical locations on the new dataset with acceptable errors when compared to the ground truth determined by an expert. However, the templates built from ANTs present better accuracy in landmark prediction when compared to the mean shape built from the Shapeworks.
    Conclusion: The average population model could be utilized to assist anatomical landmarks checking automatically and following surgical decisions for new patients who are not involved in the dataset used to generate the average population model.
    MeSH term(s) Humans ; Feasibility Studies ; Models, Statistical ; Humerus/surgery
    Language English
    Publishing date 2023-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2252548-8
    ISSN 1749-799X ; 1749-799X
    ISSN (online) 1749-799X
    ISSN 1749-799X
    DOI 10.1186/s13018-023-03870-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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