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Article ; Online: Adaptive Neural Network Control Using Nonlinear Information Gain for Permanent Magnet Synchronous Motors.

You, Sesun / Gil, Jeonghwan / Kim, Wonhee

IEEE transactions on cybernetics

2023 Volume 53, Issue 3, Page(s) 1392–1404

Abstract: In this study, an adaptive neural network (NN) control using nonlinear information (NI) gain for permanent magnet synchronous motors (PMSMs) is proposed to improve control and estimation performance. The proposed method consists of a nonlinear controller, ...

Abstract	In this study, an adaptive neural network (NN) control using nonlinear information (NI) gain for permanent magnet synchronous motors (PMSMs) is proposed to improve control and estimation performance. The proposed method consists of a nonlinear controller, a three-layer NN approximator, and NI gain. The nonlinear controller is designed via a backstepping procedure for position tracking. The commutation scheme is designed to implement the PMSM control without the direct-quadrature (DQ) transform. The three-layer NN approximator is designed to estimate the unknown complex function generated by the recursive backstepping process. The NI gains are designed to enhance the control and estimation performance according to the increased tracking errors owing to the load torque and the desired position variations. All of signals in the closed-loop system guarantee the semiglobal uniformly ultimately boundness (UUB) using the Lyapunov stability theorem and the input-to-state stability (ISS) property. The performance of the proposed method was validated by experiments performed using a PMSM testbed.
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Journal Article
ISSN	2168-2275
ISSN (online)	2168-2275
DOI	10.1109/TCYB.2021.3123614
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Article: Target Temperature Management Effect on the Clinical Outcome of Patients with Out-of-Hospital Cardiac Arrest Treated with Extracorporeal Cardiopulmonary Resuscitation: A Nationwide Observational Study.

Kim, Jae-Hee / Kim, Jae-Guk / Kang, Gu-Hyun / Jang, Yong-Soo / Kim, Wonhee / Choi, Hyun-Young / Lee, Yoonje / Ahn, Chiwon

Journal of personalized medicine

2024 Volume 14, Issue 2

Abstract: This study aimed to investigate whether targeted temperature management (TTM) could enhance outcomes in patients with out-of-hospital cardiac arrest (OHCA) treated with extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest. ... ...

Abstract	This study aimed to investigate whether targeted temperature management (TTM) could enhance outcomes in patients with out-of-hospital cardiac arrest (OHCA) treated with extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest. Using a nationwide OHCA registry, adult patients with witnessed OHCA of presumed cardiac origin who underwent ECPR at the emergency department between 2008 and 2021 were included. We examined the effect of ECPR with TTM on survival and neurological outcomes at hospital discharge using propensity score matching and multivariable logistic regression compared with patients treated with ECPR without TTM. Odds ratios and 95% confidence intervals were determined. A total of 399 ECPR cases were analyzed among 380,239 patients with OHCA. Of these, 330 underwent ECPR without TTM and 69 with TTM. After propensity score matching, 69 matched pairs of patients were included in the analysis. No significant differences in survival and good neurological outcomes between the two groups were observed. In the multivariable logistic regression, no significant differences were observed in survival and neurological outcomes between ECPR with and without TTM. Among the patients who underwent ECPR after OHCA, ECPR with TTM did not improve outcomes compared with ECPR without TTM.
Language	English
Publishing date	2024-02-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm14020185
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Article ; Online: The first complete plastome sequence from family Flagellariaceae (

Jo, Sangjin / Cho, Seonghyun / Kim, Wonhee / Kim, Ki-Joong

Mitochondrial DNA. Part B, Resources

2021 Volume 6, Issue 11, Page(s) 3164–3165

Abstract: As a part of phylogenomic study of graminids, we report the complete plastome sequence ... ...

Abstract	As a part of phylogenomic study of graminids, we report the complete plastome sequence of
Language	English
Publishing date	2021-10-07
Publishing country	England
Document type	Journal Article
ISSN	2380-2359
ISSN (online)	2380-2359
DOI	10.1080/23802359.2021.1987176
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Article ; Online: Complete chloroplast genome of

Kim, Wonhee / Ryu, Seah / Song, Ji-Hee / Sim, Sunhee

Mitochondrial DNA. Part B, Resources

2021 Volume 6, Issue 12, Page(s) 3416–3417

Abstract: We determined the complete chloroplast genome sequence of the ... ...

Abstract	We determined the complete chloroplast genome sequence of the peatmoss
Language	English
Publishing date	2021-11-22
Publishing country	England
Document type	Journal Article
ISSN	2380-2359
ISSN (online)	2380-2359
DOI	10.1080/23802359.2021.1999186
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Article ; Online: Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo.

Kim, WonHee / Watanabe, Hiroto / Lomoio, Selene / Tesco, Giuseppina

The Journal of biological chemistry

2021 Volume 296, Page(s) 100372

Abstract: Neural cell adhesion molecules 1 (NCAM1) and 2 (NCAM2) belong to the cell adhesion molecules of the immunoglobulin superfamily and have been shown to regulate formation, maturation, and maintenance of synapses. NCAM1 and NCAM2 undergo proteolysis, but ... ...

Abstract	Neural cell adhesion molecules 1 (NCAM1) and 2 (NCAM2) belong to the cell adhesion molecules of the immunoglobulin superfamily and have been shown to regulate formation, maturation, and maintenance of synapses. NCAM1 and NCAM2 undergo proteolysis, but the identity of all the proteases involved and how proteolysis is used to regulate their functions are not known. We report here that NCAM1 and NCAM2 are BACE1 substrates in vivo. NCAM1 and NCAM2 overexpressed in HEK cells were both cleaved by metalloproteinases or BACE1, and NCAM2 was also processed by γ-secretase. We identified the BACE1 cleavage site of NCAM1 (at Glu 671) and NCAM2 (at Glu 663) using mass spectrometry and site-directed mutagenesis. Next, we assessed BACE1-mediated processing of NCAM1 and NCAM2 in the mouse brain during aging. NCAM1 and NCAM2 were cleaved in the olfactory bulb of BACE1+/+ but not BACE1-/- mice at postnatal day 10 (P10), 4 and 12 months of age. In the hippocampus, a BACE1-specific soluble fragment of NCAM1 (sNCAM1β) was only detected at P10. However, we observed an accumulation of full-length NCAM1 in hippocampal synaptosomes in 4-month-old BACE1-/- mice. We also found that polysialylated NCAM1 (PSA-NCAM1) levels were increased in BACE1-/- mice at P10 and demonstrated that BACE1 cleaves both NCAM1 and PSA-NCAM1 in vitro. In contrast, we did not find evidence for BACE1-dependent NCAM2 processing in the hippocampus at any age analyzed. In summary, our data demonstrate that BACE1 differentially processes NCAM1 and NCAM2 depending on the region of brain, subcellular localization, and age in vivo.
MeSH term(s)	Amyloid Precursor Protein Secretases/metabolism ; Amyloid Precursor Protein Secretases/physiology ; Animals ; Aspartic Acid Endopeptidases/genetics ; Aspartic Acid Endopeptidases/metabolism ; Aspartic Acid Endopeptidases/physiology ; Brain/metabolism ; CD56 Antigen/metabolism ; CD56 Antigen/physiology ; Cell Adhesion Molecules/metabolism ; Female ; Hippocampus/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neural Cell Adhesion Molecule L1/metabolism ; Neural Cell Adhesion Molecules/metabolism ; Neural Cell Adhesion Molecules/physiology ; Neurons/metabolism ; Sialic Acids/metabolism ; Spatio-Temporal Analysis ; Synapses/metabolism
Chemical Substances	CD56 Antigen ; Cell Adhesion Molecules ; NCAM1 protein, human ; NCAM2 protein, human ; Ncam2 protein, mouse ; Neural Cell Adhesion Molecule L1 ; Neural Cell Adhesion Molecules ; Sialic Acids ; polysialic acid ; Amyloid Precursor Protein Secretases (EC 3.4.-) ; Aspartic Acid Endopeptidases (EC 3.4.23.-) ; BACE1 protein, human (EC 3.4.23.46) ; Bace1 protein, mouse (EC 3.4.23.46)
Language	English
Publishing date	2021-02-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2997-x
ISSN	1083-351X ; 0021-9258
ISSN (online)	1083-351X
ISSN	0021-9258
DOI	10.1016/j.jbc.2021.100372
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Article: Filibryum (Hypnaceae), a new moss genus with a new species from East Asia

Kim, Wonhee / Yamaguchi, Tomio

Journal of bryology. 2017 Apr. 3, v. 39, no. 2

2017

Abstract: Filibryum, a new genus of the family Hypnaceae, is described to include three species from East Asia. Filibryum ogatae and F. yakoushimae are transferred to it from the genus Glossadelphus, while F. deguchianum is a newly described species. The genus is ... ...

Abstract	Filibryum, a new genus of the family Hypnaceae, is described to include three species from East Asia. Filibryum ogatae and F. yakoushimae are transferred to it from the genus Glossadelphus, while F. deguchianum is a newly described species. The genus is distinguished by the absence of a central strand in the stem, prorate leaf cells, and heteroblastic and deciduous stem leaves. Molecular data suggest that the genus is closely related to Taxiphyllum and the phylogenetic position of the new genus in the Hypnaceae is supported by an approximately unbiased (AU) test.
Keywords	Hypnaceae ; bryology ; leaves ; mosses and liverworts ; new genus ; new species ; phylogeny ; East Asia
Language	English
Dates of publication	2017-0403
Size	p. 152-160.
Publishing place	Taylor & Francis
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2080324-2
ISSN	1743-2820 ; 0373-6687
ISSN (online)	1743-2820
ISSN	0373-6687
DOI	10.1080/03736687.2016.1234188
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Article ; Online: Prognostic value of targeted temperature management on outcomes of hanging-induced out-of-hospital cardiac arrest: A nationwide observational study.

Kim, Jae Guk / Choi, Hyun Young / Kang, Gu Hyun / Jang, Yong Soo / Kim, Wonhee / Lee, Yoonje

Medicine

2021 Volume 101, Issue 5, Page(s) e28688

Abstract: Abstract: This study aimed to evaluate the prognostic significance of targeted temperature management (TTM) on hanging-induced out-of-hospital cardiac arrest (OHCA) patients using nationwide data of South Korea.Adult hanging-induced OHCA patients from ... ...

Abstract	Abstract: This study aimed to evaluate the prognostic significance of targeted temperature management (TTM) on hanging-induced out-of-hospital cardiac arrest (OHCA) patients using nationwide data of South Korea.Adult hanging-induced OHCA patients from 2008 to 2018 were included in this nationwide observational study. Patients who assigned into 2 groups based on whether they did (TTM group) or did not (non-TTM group) receive TTM. Outcome measures included survival to hospital discharge and a good neurological outcome at hospital discharge.Among the 293,852 OHCA patients, 3545 patients (non-TTM, n = 2762; TTM, n = 783) were investigated. After propensity score matching for all patients, 783 matched pairs were available for analysis. We observed no significant inter-group differences in the survival to hospital discharge (non-TTM, n = 27 [3.4%] vs TTM, n = 23 [2.9%], P = .666) or good neurological outcomes (non-TTM, n = 23 [2.9%] vs TTM, n = 14 [1.8%], P = .183). In the multivariate analysis, prehospital return of spontaneous circulation (odds ratio [OR], 22.849; 95% confidence interval [CI], 11.479-45.481, P < .001) was associated with an increase in survival to hospital discharge, and age (OR, 0.971; 95% CI, 0.944-0.998, P = .035), heart disease (OR, 16.875; 95% CI, 3.028-94.036, P = .001), and prehospital return of spontaneous circulation (OR, 133.251; 95% CI, 30.512-581.930, P < .001) were significant prognostic factors of good neurological outcome. However, TTM showed no significant association with either outcome.There were no significant differences in the survival to hospital discharge and good neurological outcomes between non-TTM and TTM groups of hanging-induced OHCA patients.
MeSH term(s)	Adult ; Body Temperature ; Cardiopulmonary Resuscitation ; Humans ; Hypothermia, Induced ; Out-of-Hospital Cardiac Arrest/therapy ; Patient Discharge ; Prognosis ; Propensity Score ; Republic of Korea ; Suicide, Attempted
Language	English
Publishing date	2021-04-19
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000028688
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Article: Advanced ordered mesoporous carbon with fast Li-ion diffusion for lithium–selenium sulfide batteries in a carbonate-based electrolyte

Kim, Wonhee / Lee, Jiyeon / Lee, Seungmin / Eom, KwangSup / Pak, Chanho / Kim, Hyeong-Jin

Carbon. 2020 Dec., v. 170

2020

Abstract: Lithium-selenium sulfide (Li–SeS₂) batteries are promising next-generation batteries due to their high energy density (1124 mAh g⁻¹ and 3372 mAh cm⁻³). In a carbonate-based electrolyte, Li–SeS₂ batteries show excellent cycle life but low discharge ... ...

Abstract	Lithium-selenium sulfide (Li–SeS₂) batteries are promising next-generation batteries due to their high energy density (1124 mAh g⁻¹ and 3372 mAh cm⁻³). In a carbonate-based electrolyte, Li–SeS₂ batteries show excellent cycle life but low discharge voltage. This low discharge voltage is affected by the SeS₂ content in the composite. To increase the energy density, both the discharge voltage and SeS₂ content should be elevated simultaneously. Herein, various structures of ordered mesoporous carbons (OMCs) are investigated to overcome the low discharge voltage while containing a high SeS₂ content. By tuning the OMC structure with a large pore volume and effective morphology, Li-ion diffusion is improved, thus leading to decreased ohmic resistance and charge-transfer resistance. Even at a high SeS₂ content of 75 wt.%, a platelet-type OMC (POMC2.0) with a pore volume of 2.0 cm³ g⁻¹ enables operation at 2.0 V in a carbonate-based electrolyte. The Li–SeS₂ batteries show excellent cycle performance with an average capacity of 552 mAh g⁻¹ for 1600 cycles in a carbonate-based electrolyte.
Keywords	carbon ; electric potential difference ; electrolytes ; energy density ; porous media ; sulfides
Language	English
Dates of publication	2020-12
Size	p. 236-244.
Publishing place	Elsevier Ltd
Document type	Article
Note	NAL-AP-2-clean
ISSN	0008-6223
DOI	10.1016/j.carbon.2020.07.039
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Observer-based backstepping control method using reduced lateral dynamics for autonomous lane-keeping system.

Kang, Chang Mook / Kim, Wonhee / Chung, Chung Choo

ISA transactions

2018 Volume 83, Page(s) 214–226

Abstract: This paper presents a backstepping control method with an augmented observer for an autonomous lane-keeping system. A novel reduced second-order model is also derived for an autonomous lane-keeping system. The proposed reduced model of lateral vehicle ... ...

Abstract	This paper presents a backstepping control method with an augmented observer for an autonomous lane-keeping system. A novel reduced second-order model is also derived for an autonomous lane-keeping system. The proposed reduced model of lateral vehicle motion has the following advantages: (1) The lateral motion of the vehicle can be controlled with only simple linear second-order dynamics via the backstepping procedure; (2) The state variable of the reduced model includes the look-ahead distance similar to that for a human driver; (3) The system functions with unknown parameters and external disturbances can be lumped in the disturbance. An augmented observer is designed to estimate the full state and lumped disturbance, including the system functions with unknown parameters and external disturbances. A backstepping control is developed for improving the lateral control and compensation of the disturbance. The stability of the closed-loop system is demonstrated using the input-to-state stable property. The lateral control performance of the proposed method is validated via numerical simulations using CarSim and MATLAB/Simulink.
Language	English
Publishing date	2018-09-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2012746-7
ISSN	1879-2022 ; 0019-0578
ISSN (online)	1879-2022
ISSN	0019-0578
DOI	10.1016/j.isatra.2018.09.016
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Article: Analysis of the accuracy of automatic electrocardiogram interpretation in ST-segment elevation myocardial infarction.

Kim, Seongsoo / Kim, Wonhee / Kang, Gu Hyun / Jang, Yong Soo / Choi, Hyun Young / Kim, Jae Guk / Lee, Yoonje / Shin, Dong Geum

Clinical and experimental emergency medicine

2022 Volume 9, Issue 1, Page(s) 18–23

Abstract: Objective: This study aimed to analyze the association between the culprit artery and the diagnostic accuracy of automatic electrocardiogram (ECG) interpretation in patients with ST-segment elevation myocardial infarction (STEMI).: Methods: This ... ...

Abstract	Objective: This study aimed to analyze the association between the culprit artery and the diagnostic accuracy of automatic electrocardiogram (ECG) interpretation in patients with ST-segment elevation myocardial infarction (STEMI). Methods: This single-centered, retrospective cohort study included adult patients with STEMI who visited the emergency department between January 2017 and December 2020. The primary endpoint was the association between the culprit artery occlusion and the misinterpretation of ECG, evaluated by the chi-square test or Fisher exact test. Results: The rate of misinterpretation of the automated ECG for patients with STEMI was 26.5% (31/117 patients). There was no significant correlation between the ST segment change in the four involved leads (anteroseptal, lateral, inferior, and aVR) and the misinterpretation of ECG (all P > 0.05). Single culprit artery occlusion significantly affected the misinterpretation of ECG compared with multiple culprit artery occlusion (single vs. multiple, 27/86 [31.3%] vs. 4/31 [12.9%], P = 0.045). There was no association between culprit artery and the misinterpretation of ECG (P = 0.132). Conclusion: Single culprit artery occlusion might increase misinterpretation of ECG compared with multiple culprit artery occlusions in the automatic interpretation of STEMI.
Language	English
Publishing date	2022-03-31
Publishing country	Korea (South)
Document type	Journal Article
ISSN	2383-4625
ISSN	2383-4625
DOI	10.15441/ceem.21.163
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