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  1. Article ; Online: Exsolution Modeling and Control to Improve the Catalytic Activity of Nanostructured Electrodes.

    Kim, Yo Han / Jeong, Hyeongwon / Won, Bo-Ram / Myung, Jae-Ha

    Advanced materials (Deerfield Beach, Fla.)

    2023  Volume 35, Issue 16, Page(s) e2208984

    Abstract: In situ exsolution for nanoscale electrode design has attracted considerable attention because of its promising activity and high stability. However, fundamental research on the mechanisms underlying particle growth remains insufficient. Herein, cation- ... ...

    Abstract In situ exsolution for nanoscale electrode design has attracted considerable attention because of its promising activity and high stability. However, fundamental research on the mechanisms underlying particle growth remains insufficient. Herein, cation-diffusion-determined exsolution is presented using an analytical model based on classical nucleation and diffusion. In the designed perovskite system, the exsolution trend for particle growth is consistent with this diffusion model, which strongly depends on the initial cation concentration and reduction conditions. Based on the experimental and theoretical results, a highly Ni-doped anode and an electrochemical switching technique are employed to promote exsolution and overcome growth limitations. The optimal cell exhibits an outstanding maximum power density of 1.7 W cm
    Language English
    Publishing date 2023-03-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1474949-X
    ISSN 1521-4095 ; 0935-9648
    ISSN (online) 1521-4095
    ISSN 0935-9648
    DOI 10.1002/adma.202208984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Parturition and postpartum dietary change altered ruminal pH and the predicted functions of rumen bacterial communities but did not alter the bacterial composition in Holstein cows.

    Kim, Yo-Han / Kimura, Atsushi / Sugino, Toshihisa / Sato, Shigeru

    Frontiers in veterinary science

    2022  Volume 9, Page(s) 948545

    Abstract: We investigated the temporal dynamics of ruminal pH and the composition and predicted functions of the rumen bacterial community in Holstein cows during the periparturient period. Eight multiparous Holstein cows (body weight; 707.4 ± 29.9 kg, parity; 3.6 ...

    Abstract We investigated the temporal dynamics of ruminal pH and the composition and predicted functions of the rumen bacterial community in Holstein cows during the periparturient period. Eight multiparous Holstein cows (body weight; 707.4 ± 29.9 kg, parity; 3.6 ± 0.6) were used for continuous reticulo-ruminal pH measurement, among which five were also used for bacterial community analysis. Rumen fluid samples were collected at 3 weeks before and 2 and 6 weeks after parturition, and blood samples were collected 3 weeks before and 0, 2, 4, and 6 weeks after parturition. After the parturition, reduction in the 1-h mean reticulo-ruminal pH was associated with a significant (
    Language English
    Publishing date 2022-08-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2022.948545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effects of oral β‐cryptoxanthin administration on the transcriptomes of peripheral neutrophil and liver tissue using microarray analysis in post‐weaned Holstein calves

    Kimura, Atsushi / Kim, Yo‐Han / Hashizume, Kazuyoshi / Itō, Akira / Mukai, Katsuyuki / Kizaki, Keiichiro / Sato, Shigeru

    Journal of Animal Physiology and Animal Nutrition. 2023 Sept., v. 107, no. 5 p.1167-1175

    2023  

    Abstract: We investigated the effects of oral administration of β‐cryptoxanthin (β‐CRX), a precursor of vitamin A synthesis, on the transcriptomes of peripheral neutrophils and liver tissue in post‐weaned Holstein calves with immature immunity. A single oral ... ...

    Abstract We investigated the effects of oral administration of β‐cryptoxanthin (β‐CRX), a precursor of vitamin A synthesis, on the transcriptomes of peripheral neutrophils and liver tissue in post‐weaned Holstein calves with immature immunity. A single oral administration of β‐CRX (0.2 mg/kg body weight) was performed in eight Holstein calves (4.0 ± 0.8 months of age; 117 ± 10 kg) on Day 0. Peripheral neutrophils (n = 4) and liver tissue (n = 4) were collected on Days 0 and 7. Neutrophils were isolated by density gradient centrifugation and treated with the TRIzol reagent. mRNA expression profiles were examined by microarray and differentially expressed genes were investigated using the Ingenuity Pathway Analysis software. The differentially expressed candidate genes identified in neutrophils (COL3A1, DCN, and CCL2) and liver tissue (ACTA1) were involved in enhanced bacterial killing and maintenance of cellular homoeostasis respectively. The changes in the expression of six of the eight common genes encoding enzymes (ADH5 and SQLE) and transcription regulators (RARRES1, COBLL1, RTKN, and HES1) were in the same direction in neutrophils and liver tissue. ADH5 and SQLE are involved in the maintenance of cellular homoeostasis by increasing the availability of substrates, and RARRES1, COBLL1, RTKN, and HES1 are associated with the suppression of apoptosis and carcinogenesis. An in silico analysis revealed that MYC, which is related to the regulation of cellular differentiation and apoptosis, was the most significant upstream regulator in neutrophils and liver tissue. Transcription regulators such as CDKN2A (cell growth suppressor) and SP1 (cell apoptosis enhancer) were significantly inhibited and activated, respectively, in neutrophils and liver tissue. These results suggest that oral administration of β‐CRX promotes the expression of candidate genes related to bactericidal ability and regulation of cellular processes in peripheral neutrophils and liver cells in response to the immune‐enhancing function of β‐CRX in post‐weaned Holstein calves.
    Keywords Holstein ; animal nutrition ; animal physiology ; apoptosis ; body weight ; carcinogenesis ; cell differentiation ; cell growth ; computer simulation ; computer software ; density gradient centrifugation ; gene expression ; gene expression regulation ; immunity ; liver ; microarray technology ; neutrophils ; oral administration ; transcriptome ; vitamin A
    Language English
    Dates of publication 2023-09
    Size p. 1167-1175.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 232729-6
    ISSN 0931-2439
    ISSN 0931-2439
    DOI 10.1111/jpn.13814
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Genotyping of

    Kim, Yo-Han / Kim, Doo

    Journal of veterinary science

    2018  Volume 20, Issue 1, Page(s) 95–97

    Abstract: A total of ... ...

    Abstract A total of 123
    MeSH term(s) Animals ; Cattle ; Cattle Diseases/epidemiology ; Cattle Diseases/microbiology ; Coxiella burnetii/genetics ; Coxiella burnetii/isolation & purification ; Female ; Genotype ; Milk/microbiology ; Q Fever/epidemiology ; Q Fever/microbiology ; Q Fever/veterinary ; Republic of Korea/epidemiology
    Language English
    Publishing date 2018-12-12
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2125308-0
    ISSN 1976-555X ; 1229-845X
    ISSN (online) 1976-555X
    ISSN 1229-845X
    DOI 10.4142/jvs.2019.20.1.95
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nanoparticle Exsolution on Perovskite Oxides: Insights into Mechanism, Characteristics and Novel Strategies.

    Kim, Yo Han / Jeong, Hyeongwon / Won, Bo-Ram / Jeon, Hyejin / Park, Chan-Ho / Park, Dayoung / Kim, Yeeun / Lee, Somi / Myung, Jae-Ha

    Nano-micro letters

    2023  Volume 16, Issue 1, Page(s) 33

    Abstract: Supported nanoparticles have attracted considerable attention as a promising catalyst for achieving unique properties in numerous applications, including fuel cells, chemical conversion, and batteries. Nanocatalysts demonstrate high activity by expanding ...

    Abstract Supported nanoparticles have attracted considerable attention as a promising catalyst for achieving unique properties in numerous applications, including fuel cells, chemical conversion, and batteries. Nanocatalysts demonstrate high activity by expanding the number of active sites, but they also intensify deactivation issues, such as agglomeration and poisoning, simultaneously. Exsolution for bottom-up synthesis of supported nanoparticles has emerged as a breakthrough technique to overcome limitations associated with conventional nanomaterials. Nanoparticles are uniformly exsolved from perovskite oxide supports and socketed into the oxide support by a one-step reduction process. Their uniformity and stability, resulting from the socketed structure, play a crucial role in the development of novel nanocatalysts. Recently, tremendous research efforts have been dedicated to further controlling exsolution particles. To effectively address exsolution at a more precise level, understanding the underlying mechanism is essential. This review presents a comprehensive overview of the exsolution mechanism, with a focus on its driving force, processes, properties, and synergetic strategies, as well as new pathways for optimizing nanocatalysts in diverse applications.
    Language English
    Publishing date 2023-11-28
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2642093-4
    ISSN 2150-5551 ; 2150-5551
    ISSN (online) 2150-5551
    ISSN 2150-5551
    DOI 10.1007/s40820-023-01258-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Ulmus davidiana

    Kim, Iljin / Seo, Jieun / Lee, Dong Hyun / Kim, Yo-Han / Kim, Jun-Hyung / Wie, Myung-Bok / Byun, Jun-Kyu / Yun, Jang-Hyuk

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1138676

    Abstract: Diabetic retinopathy (DR) is a disease that causes visual deficiency owing to vascular leakage or abnormal angiogenesis. Pericyte apoptosis is considered one of the main causes of vascular leakage in diabetic retina, but there are few known therapeutic ... ...

    Abstract Diabetic retinopathy (DR) is a disease that causes visual deficiency owing to vascular leakage or abnormal angiogenesis. Pericyte apoptosis is considered one of the main causes of vascular leakage in diabetic retina, but there are few known therapeutic agents that prevent it.
    MeSH term(s) Diabetic Retinopathy/drug therapy ; Diabetic Retinopathy/prevention & control ; Diabetic Retinopathy/pathology ; Pericytes ; Ulmus ; Endothelial Cells/pathology ; Apoptosis ; Diabetes Mellitus/pathology
    Language English
    Publishing date 2023-05-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1138676
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Predicted functional analysis of rumen microbiota suggested the underlying mechanisms of the postpartum subacute ruminal acidosis in Holstein cows.

    Tsuchiya, Yoshiyuki / Chiba, Ena / Kimura, Atsushi / Kawashima, Kenji / Hasunuma, Toshiya / Kushibiki, Shiro / Kim, Yo-Han / Sato, Shigeru

    Journal of veterinary science

    2023  Volume 24, Issue 2, Page(s) e27

    Abstract: Background: The relationships between the postpartum subacute ruminal acidosis (SARA) occurrence and predicted bacterial functions during the periparturient period are still not clear in Holstein cows.: Objectives: The present study was performed to ... ...

    Abstract Background: The relationships between the postpartum subacute ruminal acidosis (SARA) occurrence and predicted bacterial functions during the periparturient period are still not clear in Holstein cows.
    Objectives: The present study was performed to investigate the alterations of rumen fermentation, bacterial community structure, and predicted bacterial functional pathways in Holstein cows.
    Methods: Holstein cows were divided into the SARA (n = 6) or non-SARA (n = 4) groups, depending on whether they developed SARA during the first 2 weeks after parturition. Reticulo-ruminal pH was measured continuously during the study period. Reticulo-ruminal fluid samples were collected 3 weeks prepartum, and 2 and 6 weeks postpartum, and blood samples were collected 3 weeks before, 0, 2, 4 and 6 weeks postpartum.
    Results: The postpartum decline in 7-day mean reticulo-ruminal pH was more severe and longer-lasting in the SARA group compared with the non-SARA group. Changes in predicted functional pathways were identified in the SARA group. A significant upregulation of pathway "PWY-6383" associated with Mycobacteriaceae species was identified at 3 weeks after parturition in the SARA group. Significantly identified pathways involved in denitrification (DENITRIFICATION-PWY and PWY-7084), detoxification of reactive oxygen and nitrogen species (PWY1G-0), and starch degradation (PWY-622) in the SARA group were downregulated.
    Conclusions: The postpartum SARA occurrence is likely related to the predicted functions of rumen bacterial community rather than the alterations of rumen fermentation or fluid bacterial community structure. Therefore, our result suggests the underlying mechanisms, namely functional adaptation of bacterial community, causing postpartum SARA in Holstein cows during the periparturient period.
    MeSH term(s) Female ; Cattle ; Animals ; Rumen/metabolism ; Diet/veterinary ; Cattle Diseases/microbiology ; Postpartum Period ; Acidosis/veterinary ; Acidosis/metabolism ; Microbiota ; Lactation/physiology
    Language English
    Publishing date 2023-04-03
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2125308-0
    ISSN 1976-555X ; 1976-555X
    ISSN (online) 1976-555X
    ISSN 1976-555X
    DOI 10.4142/jvs.22246
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of oral β-cryptoxanthin administration on the transcriptomes of peripheral neutrophil and liver tissue using microarray analysis in post-weaned Holstein calves.

    Kimura, Atsushi / Kim, Yo-Han / Hashizume, Kazuyoshi / Ito, Akira / Mukai, Katsuyuki / Kizaki, Keiichiro / Sato, Shigeru

    Journal of animal physiology and animal nutrition

    2023  Volume 107, Issue 5, Page(s) 1167–1175

    Abstract: We investigated the effects of oral administration of β-cryptoxanthin (β-CRX), a precursor of vitamin A synthesis, on the transcriptomes of peripheral neutrophils and liver tissue in post-weaned Holstein calves with immature immunity. A single oral ... ...

    Abstract We investigated the effects of oral administration of β-cryptoxanthin (β-CRX), a precursor of vitamin A synthesis, on the transcriptomes of peripheral neutrophils and liver tissue in post-weaned Holstein calves with immature immunity. A single oral administration of β-CRX (0.2 mg/kg body weight) was performed in eight Holstein calves (4.0 ± 0.8 months of age; 117 ± 10 kg) on Day 0. Peripheral neutrophils (n = 4) and liver tissue (n = 4) were collected on Days 0 and 7. Neutrophils were isolated by density gradient centrifugation and treated with the TRIzol reagent. mRNA expression profiles were examined by microarray and differentially expressed genes were investigated using the Ingenuity Pathway Analysis software. The differentially expressed candidate genes identified in neutrophils (COL3A1, DCN, and CCL2) and liver tissue (ACTA1) were involved in enhanced bacterial killing and maintenance of cellular homoeostasis respectively. The changes in the expression of six of the eight common genes encoding enzymes (ADH5 and SQLE) and transcription regulators (RARRES1, COBLL1, RTKN, and HES1) were in the same direction in neutrophils and liver tissue. ADH5 and SQLE are involved in the maintenance of cellular homoeostasis by increasing the availability of substrates, and RARRES1, COBLL1, RTKN, and HES1 are associated with the suppression of apoptosis and carcinogenesis. An in silico analysis revealed that MYC, which is related to the regulation of cellular differentiation and apoptosis, was the most significant upstream regulator in neutrophils and liver tissue. Transcription regulators such as CDKN2A (cell growth suppressor) and SP1 (cell apoptosis enhancer) were significantly inhibited and activated, respectively, in neutrophils and liver tissue. These results suggest that oral administration of β-CRX promotes the expression of candidate genes related to bactericidal ability and regulation of cellular processes in peripheral neutrophils and liver cells in response to the immune-enhancing function of β-CRX in post-weaned Holstein calves.
    MeSH term(s) Animals ; Cattle ; Neutrophils ; Transcriptome ; Beta-Cryptoxanthin/metabolism ; Liver/metabolism ; Microarray Analysis/veterinary
    Chemical Substances Beta-Cryptoxanthin
    Language English
    Publishing date 2023-03-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 232729-6
    ISSN 1439-0396 ; 0044-3565 ; 0931-2439
    ISSN (online) 1439-0396
    ISSN 0044-3565 ; 0931-2439
    DOI 10.1111/jpn.13814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Progress of polysaccharide-based tissue adhesives.

    Han, Gi-Yeon / Kwack, Ho-Wook / Kim, Yo-Han / Je, Yeon Ho / Kim, Hyun-Joong / Cho, Chong-Su

    Carbohydrate polymers

    2023  Volume 327, Page(s) 121634

    Abstract: Recently, polymer-based tissue adhesives (TAs) have gained the attention of scientists and industries as alternatives to sutures for sealing and closing wounds or incisions because of their ease of use, low cost, minimal tissue damage, and short ... ...

    Abstract Recently, polymer-based tissue adhesives (TAs) have gained the attention of scientists and industries as alternatives to sutures for sealing and closing wounds or incisions because of their ease of use, low cost, minimal tissue damage, and short application time. However, poor mechanical properties and weak adhesion strength limit the application of TAs, although numerous studies have attempted to develop new TAs with enhanced performance. Therefore, next-generation TAs with improved multifunctional properties are required. In this review, we address the requirements of polymeric TAs, adhesive characteristics, adhesion strength assessment methods, adhesion mechanisms, applications, advantages and disadvantages, and commercial products of polysaccharide (PS)-based TAs, including chitosan (CS), alginate (AL), dextran (DE), and hyaluronic acid (HA). Additionally, future perspectives are discussed.
    MeSH term(s) Tissue Adhesives ; Polysaccharides ; Polymers ; Chitosan ; Alginates ; Adhesives
    Chemical Substances Tissue Adhesives ; Polysaccharides ; Polymers ; Chitosan (9012-76-4) ; Alginates ; Adhesives
    Language English
    Publishing date 2023-11-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1501516-6
    ISSN 1879-1344 ; 0144-8617
    ISSN (online) 1879-1344
    ISSN 0144-8617
    DOI 10.1016/j.carbpol.2023.121634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Prevention of Postoperative Complications by Prepectoral versus Subpectoral Breast Reconstruction: A Systematic Review and Meta-Analysis.

    Kim, Yo-Han / Yang, Yun-Jung / Lee, Dong-Won / Song, Seung-Yong / Lew, Dae-Hyun / Yang, Eun-Jung

    Plastic and reconstructive surgery

    2023  Volume 153, Issue 1, Page(s) 10e–24e

    Abstract: Background: Implant-based breast reconstruction has evolved over time. However, the effects of prepectoral breast reconstruction (PBR) compared with those of subpectoral breast reconstruction (SBR) have not been clearly defined. Therefore, this study ... ...

    Abstract Background: Implant-based breast reconstruction has evolved over time. However, the effects of prepectoral breast reconstruction (PBR) compared with those of subpectoral breast reconstruction (SBR) have not been clearly defined. Therefore, this study aimed to compare the occurrence of surgical complications between PBR and SBR to determine the procedure that is effective and relatively safe.
    Methods: The PubMed, Cochrane Library, and EMBASE databases were searched for studies published until April of 2021 comparing PBR and SBR following mastectomy. Two authors independently assessed the risk of bias. General information on the studies and surgical outcomes were extracted. Among 857 studies, 34 and 29 were included in the systematic review and meta-analysis, respectively. Subgroup analysis was performed to clearly compare the results of patients who underwent postmastectomy radiation therapy.
    Results: Pooled results showed that prevention of capsular contracture (OR, 0.57; 95% CI, 0.41 to 0.79) and infection control (OR, 0.73; 95% CI, 0.58 to 0.92) were better with PBR than with SBR. Rates of hematoma, implant loss, seroma, skin-flap necrosis, and wound dehiscence were not significantly different between PBR and SBR. PBR considerably improved postoperative pain, BREAST-Q score, and upper arm function compared with SBR. Among postmastectomy radiation therapy patients, the incidence rates of capsular contracture were significantly lower in the PBR group than in the SBR group (OR, 0.14; 95% CI, 0.05 to 0.35).
    Conclusions: The results showed that PBR had fewer postoperative complications than SBR. The authors' meta-analysis suggests that PBR could be used as an alternative technique for breast reconstruction in appropriate patients.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/etiology ; Mastectomy/adverse effects ; Mastectomy/methods ; Breast Implantation/adverse effects ; Breast Implantation/methods ; Mammaplasty/adverse effects ; Mammaplasty/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Contracture/etiology ; Breast Implants/adverse effects
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208012-6
    ISSN 1529-4242 ; 0032-1052 ; 0096-8501
    ISSN (online) 1529-4242
    ISSN 0032-1052 ; 0096-8501
    DOI 10.1097/PRS.0000000000010493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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