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Article: Chronic obstructive pulmonary disease: respiratory review of 2013.

Kim, Yu-Il

2014 Volume 76, Issue 2, Page(s) 53–58

Abstract: Chronic obstructive pulmonary disease (COPD) is a common airway disease that has considerable impact on disease burdens and mortality rates. A large number of articles on COPD are published within the last few years. Many aspects on COPD ranging from ... ...

Abstract	Chronic obstructive pulmonary disease (COPD) is a common airway disease that has considerable impact on disease burdens and mortality rates. A large number of articles on COPD are published within the last few years. Many aspects on COPD ranging from risk factors to management have continued to be fertile fields of investigation. This review summarizes 6 clinical articles with regards to the risk factors, phenotype, assessment, exacerbation, management and prognosis of patients with COPD which were being published last year in major medical journals.
Language	English
Publishing date	2014-02-27
Publishing country	Korea (South)
Document type	Journal Article ; Review
ZDB-ID	2161256-0
ISSN	1738-3536 ; 0378-0066
ISSN	1738-3536 ; 0378-0066
DOI	10.4046/trd.2014.76.2.53
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Article ; Online: Intraosseous Hemangioma of Nasal Bone: Unusual Cause of Epiphora.

Choi, Jung Sik / Kim, Seong Ae / Kim, Yu Il / Lee, Jung Ho

The Journal of craniofacial surgery

2020 Volume 31, Issue 7, Page(s) e722–e723

Abstract: Intraosseous hemangioma is very rare, accounting for <1% of bone tumors. Nasal bone origin of it is even rarer. A 63-year-old female patient visited our clinic with a complaint of epiphora. On physical examination, about 2-cm-sized nontender and fixed ... ...

Abstract	Intraosseous hemangioma is very rare, accounting for <1% of bone tumors. Nasal bone origin of it is even rarer. A 63-year-old female patient visited our clinic with a complaint of epiphora. On physical examination, about 2-cm-sized nontender and fixed mass was palpated along the left nasomaxillary suture area. Preoperative magnetic resonance imaging findings were consistent with intraosseous hemangioma originating from the nasal bone. Epiphora was thought to be developed due to the mass effect and a marginal resection of the mass was performed. The defect was reconstructed with a septal cartilage and porous polyethylene implant (Synpor). Postoperatively, epiphora subsided and there has been no sign of recurrence or facial deformity during 6 months of follow-up.
MeSH term(s)	Bone Neoplasms/surgery ; Cranial Sutures/pathology ; Female ; Hemangioma/complications ; Hemangioma/surgery ; Humans ; Lacrimal Apparatus Diseases/etiology ; Lacrimal Apparatus Diseases/surgery ; Magnetic Resonance Imaging ; Middle Aged ; Nasal Bone/diagnostic imaging ; Nasal Bone/surgery ; Neoplasm Recurrence, Local
Language	English
Publishing date	2020-06-27
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000006710
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Article: Three cases of rigid bronchoscopic removal of carinal masses: Case report.

Lee, Jae-Kyeong / Kho, Bo-Gun / Kim, Tae-Ok / Shin, Hong-Joon / Kim, Yu-Il / Lim, Sung-Chul / Choi, Yoo-Duk / Kwon, Yong-Soo

Respiratory medicine case reports

2022 Volume 40, Page(s) 101759

Abstract: Tracheal tumors are rare diseases. They can cause narrowing of a central airway, a severe respiratory distress, and death. The objective of this case series is to highlight the role of rigid bronchoscopy in diagnosing and treating carina masses which are ...

Abstract	Tracheal tumors are rare diseases. They can cause narrowing of a central airway, a severe respiratory distress, and death. The objective of this case series is to highlight the role of rigid bronchoscopy in diagnosing and treating carina masses which are difficult to remove surgically. Tumor excision was performed by the rigid bronchoscopic intervention. Additional treatment was administered according to the diagnosis of each individual patient. After the procedure, patients' symptoms were improved and stenotic central airways were reopened. Rigid bronchoscopy can be a good therapeutic option to reestablish airway patency and a bridge treatment for further definitive treatment.
Language	English
Publishing date	2022-10-25
Publishing country	England
Document type	Case Reports
ZDB-ID	2666110-X
ISSN	2213-0071
ISSN	2213-0071
DOI	10.1016/j.rmcr.2022.101759
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Article ; Online: Differences in clinical significance of bronchodilator responses measured by forced expiratory volume in 1 second and forced vital capacity.

Choi, Joon Young / Kim, Sung Kyoung / Lee, Jin Hwa / Jung, Ki-Suck / Yoo, Kwang Ha / Hwang, Ki-Eun / Lee, Jong Deog / Kim, Yu-Il / Yoon, Hyoung Kyu / Um, Soo-Jung

PloS one

2023 Volume 18, Issue 2, Page(s) e0282256

Abstract: Background: The clinical implication of bronchodilator response (BDR) is not fully understood. However, BDR is frequently present in patients with chronic obstructive pulmonary disease (COPD). We identified the differences in clinical features regarding ...

Abstract	Background: The clinical implication of bronchodilator response (BDR) is not fully understood. However, BDR is frequently present in patients with chronic obstructive pulmonary disease (COPD). We identified the differences in clinical features regarding BDR. In addition, we divided BDR into BDR for forced expiratory volume in 1 s (FEV1) and BDR for forced vital capacity (FVC; i.e., BDR-FEV1 and BDR-FVC, respectively) and analyzed clinical significance. Methods: We used data from the Korea COPD Subgroup Study, a multicenter cohort study of COPD patients recruited from 54 centers in South Korea since April 2012. We analyzed differences in baseline characteristics, 1-year exacerbation rate, and 3-year FEV1 decline between BDR negative and positive patients. Moreover, we analyzed the differences in clinical features between BDR-FEV1 positive and negative patients and between BDR-FVC positive and negative patients. Results: Of the 2,181 patients enrolled in this study, 366 (16.8%) were BDR positive. BDR positive patients were more likely to be ever-smokers and to have a lower body mass index and higher symptom scores compared to BDR negative patients. Baseline FEV1 and FEV1/FVC were lower in the BDR positive compared to the BDR negative group (1.7 ± 0.6 and 1.6 ± 0.5, respectively, p < 0.01; 50.9 ± 12.1 and 46.5 ± 14.8, respectively, p < 0.01). BDR positive patients were more likely to have been diagnosed with asthma-COPD overlap and to receive inhaled corticosteroids (ICS) than BDR negative patients. BDR-FVC patients were more likely to be smokers, suffer from worse symptoms and have lower lung function than those with no BDR-FVC. BDR had no significant effect on 1-year moderate to severe or severe exacerbation rates or 3-year annual FEV1 decline. Interactive effects of ICS and BDR on the exacerbation rate were not significant in any group. Conclusions: In this study, BDR positive patients were more likely to be ever-smokers and to have worse symptoms and lung function than BDR negative patients. BDR-FVC was associated with worse symptom control and lung function compared to BDR-FEV1. However, there were no significant differences in exacerbation rate or decline in lung function in any BDR group. In addition, the effects of ICS on exacerbations were not significant in any group.
MeSH term(s)	Humans ; Bronchodilator Agents/therapeutic use ; Forced Expiratory Volume/physiology ; Cohort Studies ; Clinical Relevance ; Pulmonary Disease, Chronic Obstructive ; Vital Capacity/physiology ; Adrenal Cortex Hormones/therapeutic use
Chemical Substances	Bronchodilator Agents ; Adrenal Cortex Hormones
Language	English
Publishing date	2023-02-24
Publishing country	United States
Document type	Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0282256
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Article: When is LABA/LAMA Better than LAMA in GOLD Group B or D Patients for Reducing Acute Exacerbations of COPD?

Shin, Hong-Joon / Kim, Yu-Il / Kim, Youlim / Lee, Chang Youl / Ra, Seung Won / Moon, Ji-Yong / Jung, Ki-Suck / Yoo, Kwang Ha / Shin, Kyeong-Cheol / Lim, Sung-Chul

Chonnam medical journal

2023 Volume 59, Issue 3, Page(s) 180–187

Abstract: Long-acting ... ...

Abstract	Long-acting β
Language	English
Publishing date	2023-09-25
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2536217-3
ISSN	2233-7393 ; 2233-7385 ; 0377-9564
ISSN (online)	2233-7393
ISSN	2233-7385 ; 0377-9564
DOI	10.4068/cmj.2023.59.3.180
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Article ; Online: Associations between depression and anxiety index and frequency of acute exacerbation in chronic obstructive pulmonary disease.

Hong, Yu Jin / Kim, Youlim / Moon, Ji-Yong / Park, Shinhee / Lee, Jung-Kyu / Jung, Ki-Suck / Yoo, Kwang Ha / Kim, Yu-Il / Choi, Joon Young

Therapeutic advances in respiratory disease

2023 Volume 17, Page(s) 17534666231216591

Abstract: Background: Comorbidities of chronic obstructive pulmonary disease (COPD) influence clinical characteristics and prognosis.: Objectives: This study compared the clinical characteristics and exacerbation rate of COPD according to the presence of ... ...

Abstract	Background: Comorbidities of chronic obstructive pulmonary disease (COPD) influence clinical characteristics and prognosis. Objectives: This study compared the clinical characteristics and exacerbation rate of COPD according to the presence of depression or anxiety. Design: This study used data from The Korea COPD Subgroup Study (KOCOSS) cohort, a nationwide prospective cohort from 54 medical centers, between April 2012 and 2019. Methods: Depression and anxiety were diagnosed with the Beck Depression Inventory and Beck Anxiety Inventory. Negative binomial regression analysis was performed to analyze the frequency of exacerbations in depressed patients and anxiety. Differences in lung function trajectory according to presence of depression/anxiety were analyzed using a linear mixed model. Results: In all, 2147 patients were enrolled. Depressed patients or anxiety had lower lung function, higher modified Medical Research Council (mMRC) grade, St. George Respiratory Questionnaire (SGRQ) score, and COPD assessment test score, and higher rates of exacerbation in the past year than those without depression/anxiety. Depressed patients had a higher frequency of moderate to severe exacerbations [Incidence Rate Ratio (IRR): 1.57, CI: 1.17-2.11, Conclusion: Depressed and anxious patients showed increased respiratory symptoms and exacerbation rate as well as reduced health-related quality of life, whereas there were no significant differences in changes in lung function between groups with and without depression/anxiety.
MeSH term(s)	Humans ; Depression/diagnosis ; Depression/epidemiology ; Prospective Studies ; Quality of Life ; Anxiety/diagnosis ; Anxiety/epidemiology ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/epidemiology
Language	English
Publishing date	2023-11-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2476459-0
ISSN	1753-4666 ; 1753-4658
ISSN (online)	1753-4666
ISSN	1753-4658
DOI	10.1177/17534666231216591
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Zs.A 6753: Show issues

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Article ; Online: Major adverse cardiovascular events and hyperuricemia during tuberculosis treatment.

Shin, Hong-Joon / Yoon, Joon-Young / Na, Young-Ok / Lee, Jae-Kyeong / Kho, Bo Gun / Kim, Tae-Ok / Kim, Yu-Il / Lim, Sung-Chul / Jeong, Sae-Hee / Kwon, Yong-Soo

PloS one

2023 Volume 18, Issue 11, Page(s) e0294490

Abstract: Background: Hyperuricemia is common during tuberculosis (TB) treatment, especially in association with pyrazinamide (PZA). This study investigated the relationship between major adverse cardiovascular events (MACEs) and hyperuricemia during TB treatment. ...

Abstract	Background: Hyperuricemia is common during tuberculosis (TB) treatment, especially in association with pyrazinamide (PZA). This study investigated the relationship between major adverse cardiovascular events (MACEs) and hyperuricemia during TB treatment. Methods: We conducted a single-center retrospective cohort study. From January 2010 through June 2017, we assessed all consecutive TB patients at Chonnam National University Hospital in South Korea. Hyperuricemia was defined as serum uric acid levels exceeding 7.0 mg/dL (men) and 6.0 mg/dL (women). Results: Of the 1,143 patients included, PZA was administered to 1,081 (94.6%), and hyperuricemia was detected in 941 (82.3%). Eight patients experienced MACEs. Multivariate analysis using logistic regression indicated that prior ischemic heart disease was associated with MACE development (OR,14.087; 95% CI,3.304-60.061; P < 0.000), while hyperuricemia was not (OR, 1.505; 95% CI, 0.184-12.299; P = 0.703). For patients without drug-resistant TB, the absence of hyperuricemia was associated with higher mortality (OR, 2.609; 95% CI, 1.066-6.389; P = 0.036), whereas hyperuricemia was associated with less worse outcomes (OR,0.316; 95% CI,0.173-0.576; P < 0.000). Conclusions: Although most patients treated with PZA developed hyperuricemia, it was not associated with MACE development. Hyperuricemia during TB treatment was associated with better outcomes, possibly due to consistent adherence to TB treatment.
MeSH term(s)	Male ; Humans ; Female ; Antitubercular Agents/adverse effects ; Retrospective Studies ; Hyperuricemia/complications ; Hyperuricemia/drug therapy ; Uric Acid ; Tuberculosis, Multidrug-Resistant/drug therapy ; Myocardial Ischemia/drug therapy
Chemical Substances	Antitubercular Agents ; Uric Acid (268B43MJ25)
Language	English
Publishing date	2023-11-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0294490
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Article ; Online: Effective Timing of Introducing an Inpatient Smoking Cessation Program to Cancer Patients.

Choe, Yu-Ri / Choi, Ji-Won / Jeong, Ju-Ri / Doh, Hye-Mi / Kim, Mi-Lee / Nam, Min-Seol / Kho, Hee-Ji / Park, Ha-Young / Ahn, Hye-Ran / Kweon, Sun-Seog / Kim, Yu-Il / Oh, In-Jae

Yonsei medical journal

2023 Volume 64, Issue 4, Page(s) 251–258

Abstract: Purpose: We aimed to identify factors influencing smoking cessation success among cancer patients registered in an inpatient smoking cessation program at a single cancer center.: Materials and methods: The electronic medical records of enrolled ... ...

Abstract	Purpose: We aimed to identify factors influencing smoking cessation success among cancer patients registered in an inpatient smoking cessation program at a single cancer center. Materials and methods: The electronic medical records of enrolled patients with solid cancer were retrospectively reviewed. We evaluated factors associated with 6-month smoking cessation. Results: A total of 458 patients with cancer were included in this study. Their mean age was 62.9±10.3 years, and 56.3% of the participants had lung cancer. 193 (42.1%) had not yet begun their main treatment. The mean number of counseling sessions for the participants was 8.4±3.5, and 46 (10.0%) patients were prescribed smoking cessation medications. The 6-month smoking cessation success rate was 48.0%. Multivariate analysis showed that younger age (<65 years), cohabited status, early stage, and the number of counseling sessions were statistically significant factors affecting 6-month smoking cessation success ( Conclusion: Smoking cessation intervention must be considered when establishing a treatment plan immediately after a cancer diagnosis among smokers.
MeSH term(s)	Humans ; Middle Aged ; Aged ; Smoking Cessation/psychology ; Inpatients ; Retrospective Studies ; Counseling ; Lung Neoplasms
Language	English
Publishing date	2023-03-30
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	303740-x
ISSN	1976-2437 ; 0513-5796
ISSN (online)	1976-2437
ISSN	0513-5796
DOI	10.3349/ymj.2022.0499
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Article ; Online: Paradoxical pulmonary hemorrhage associated with hemocoagulase batroxobin in a patient with hemoptysis: A CARE-compliant case report.

Kim, Tae-Ok / Kim, Min-Suk / Kho, Bo Gun / Park, Ha Young / Kwon, Yong-Soo / Kim, Yu-Il / Lim, Sung-Chul / Shin, Hong-Joon

Medicine

2021 Volume 100, Issue 4, Page(s) e24040

Abstract: Rational: Hemocoagulase, a hemostatic, is used in patients with trauma, gastrointestinal bleeding, or pulmonary hemorrhage or those undergoing surgery. However, paradoxical bleeding after hemocoagulase administration is not considered a clinically ... ...

Abstract	Rational: Hemocoagulase, a hemostatic, is used in patients with trauma, gastrointestinal bleeding, or pulmonary hemorrhage or those undergoing surgery. However, paradoxical bleeding after hemocoagulase administration is not considered a clinically significant adverse effect. Here, we report a case of paradoxical pulmonary hemorrhage associated with hypofibrinogenemia after administration of the hemocoagulase batroxobin in a patient with hemoptysis. Patient concerns: An 86-year-old woman complained of hemoptysis during hospitalization with organophosphate poisoning. Hemocoagulase was administered to manage bleeding; however, bleeding signs, such as hemoptysis, massive epistaxis, and ecchymosis, recurred. Diagnoses: The patient was diagnosed with acquired hypofibrinogenemia on the basis of the reduced plasma fibrinogen level after hemocoagulase administration and lack of other causes of bleeding. Intervention: Hemocoagulase administration was discontinued, and fibrinogen-containing plasma products were administered. Outcomes: The plasma fibrinogen level normalized and bleeding signs did not recur. Lessons: It is necessary to measure plasma fibrinogen levels regularly in patients undergoing hemocoagulase administration and discontinue its administration when acquired hypofibrinogenemia is detected.
MeSH term(s)	Afibrinogenemia/complications ; Afibrinogenemia/drug therapy ; Aged, 80 and over ; Batroxobin/adverse effects ; Batroxobin/therapeutic use ; Female ; Fibrinogen/administration & dosage ; Hemoptysis/etiology ; Hemorrhage/etiology ; Hemostatics ; Humans ; Lung Diseases/etiology
Chemical Substances	Hemostatics ; Fibrinogen (9001-32-5) ; Batroxobin (EC 3.4.21.-)
Language	English
Publishing date	2021-02-02
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000024040
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Article ; Online: Response.

Choi, Joon Young / Kim, Ki Uk / Kim, Deog Kyeom / Kim, Yu-Il / Kim, Tae-Hyung / Lee, Won-Yeon / Park, Seong Ju / Park, Yong Bum / Song, Jin Woo / Shin, Kyeong-Cheol / Um, Soo-Jung / Yoo, Kwang Ha / Yoon, Hyoung Kyu / Lee, Chang Youl / Lee, Ho Sung / Leem, Ah Young / Choi, Won-Il / Lim, Seong Yong / Rhee, Chin Kook

Chest

2024 Volume 165, Issue 4, Page(s) e126–e128

Language	English
Publishing date	2024-03-16
Publishing country	United States
Document type	Letter
ZDB-ID	1032552-9
ISSN	1931-3543 ; 0012-3692
ISSN (online)	1931-3543
ISSN	0012-3692
DOI	10.1016/j.chest.2023.11.003
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