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  1. Book ; Online: Teaching Federalism

    Kincaid, John / Leckrone, J. Wesley

    Multidimensional Approaches

    (Elgar Guides to Teaching)

    2023  

    Series title Elgar Guides to Teaching
    Keywords JNU ; JPP ; JPR ; JPA ; federalism ; teaching ; concepts of federalism ; federalism case studies ; intergovernmental relations ; indigenous peoples ; secession
    Language English
    Size 1 electronic resource (306 pages)
    Publisher Edward Elgar Publishing
    Publishing place Cheltenham
    Document type Book ; Online
    Note English
    HBZ-ID HT030377700
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Courts in Federal Countries

    Aroney, Nicholas / Kincaid, John

    2017  

    Abstract: Courts are key players in the dynamics of federal countries since their rulings have a direct impact on the ability of governments to centralize and decentralize power. Courts in Federal Countries examines the role high courts play in thirteen countries, ...

    Abstract Courts are key players in the dynamics of federal countries since their rulings have a direct impact on the ability of governments to centralize and decentralize power. Courts in Federal Countries examines the role high courts play in thirteen countries, including Australia, Brazil, Canada, Germany, India, Nigeria, Spain, and the United States. The volume's contributors analyse the centralizing or decentralizing forces at play following a court's ruling on issues such as individual rights, economic affairs, social issues, and other matters. The thirteen substantive chapters have been written to facilitate comparability between the countries. Each chapter outlines a country's federal system, explains the constitutional and institutional status of the court system, and discusses the high court's jurisprudence in light of these features. Courts in Federal Countries offers insightful explanations of judicial behaviour in the world's leading federations
    Size 1 electronic resource ( p.)
    Publisher University of Toronto Press
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020093841
    ISBN 9781487500627 ; 9781487514662 ; 1487500629 ; 1487514662
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: The discovery of human monogenic obesity.

    Kincaid, John W R

    Nature reviews. Endocrinology

    2023  Volume 19, Issue 7, Page(s) 381

    MeSH term(s) Humans ; Obesity/epidemiology ; Obesity/genetics ; Leptin/genetics ; Mutation
    Chemical Substances Leptin
    Language English
    Publishing date 2023-05-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/s41574-023-00844-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Upper extremity neuropathies.

    Kincaid, John C

    Handbook of clinical neurology

    2019  Volume 161, Page(s) 197–205

    Abstract: This chapter covers the electrodiagnostic (EDX) evaluation of upper extremity nerves and the brachial plexus. Carpal tunnel syndrome is the most common peripheral nerve disorder of the upper extremity. A number of techniques are used but there is no gold ...

    Abstract This chapter covers the electrodiagnostic (EDX) evaluation of upper extremity nerves and the brachial plexus. Carpal tunnel syndrome is the most common peripheral nerve disorder of the upper extremity. A number of techniques are used but there is no gold standard approach for its diagnosis. Needle EMG aids in the differentiation of proximal and distal median neuropathies. Ulnar neuropathy at the elbow and ulnar neuropathy at or distal to the wrist can be distinguished by EDX techniques. Radial neuropathy at the spiral groove has a specific EDX pattern. EDX assessment of proximal upper extremity nerve lesions such as brachial plexopathy is a valuable tool for exploring the diagnosis and differential diagnosis of this complex disorder.
    MeSH term(s) Electrodiagnosis/methods ; Humans ; Peripheral Nervous System Diseases/diagnosis ; Upper Extremity
    Language English
    Publishing date 2019-07-15
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-444-64142-7.00049-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Nerve Conduction Studies: Basic Concepts and Patterns of Abnormalities.

    O'Bryan, Rebecca / Kincaid, John

    Neurologic clinics

    2021  Volume 39, Issue 4, Page(s) 897–917

    Abstract: Nerve conduction studies are a key component of the electrophysiologic evaluation of the peripheral nerve system, and provide important information about the integrity of the large, myelinated axons, neuromuscular junctions, and muscle. Nerve conduction ... ...

    Abstract Nerve conduction studies are a key component of the electrophysiologic evaluation of the peripheral nerve system, and provide important information about the integrity of the large, myelinated axons, neuromuscular junctions, and muscle. Nerve conduction studies involve eliciting nerve action potentials at sites along a peripheral nerve and recording the response from another site along the nerve or from a muscle innervated by that nerve. Attention to details of test performance, use of well-established normative values, and knowledge of the patterns of abnormality produced by disorders that affect neuronal, axonal, and myelin sheath function are fundamental for proper interpretation of results.
    MeSH term(s) Axons ; Humans ; Myelin Sheath ; Neural Conduction ; Neuromuscular Junction
    Language English
    Publishing date 2021-09-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1013148-6
    ISSN 1557-9875 ; 0733-8619
    ISSN (online) 1557-9875
    ISSN 0733-8619
    DOI 10.1016/j.ncl.2021.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Neurophysiologic Studies in the Evaluation of Polyneuropathy.

    Kincaid, John C

    Continuum (Minneapolis, Minn.)

    2017  Volume 23, Issue 5, Peripheral Nerve and Motor Neuron Disorders, Page(s) 1263–1275

    Abstract: Purpose of review: This article provides core information on the clinical neurophysiology techniques available for the investigation of disorders of the peripheral nervous system.: Recent findings: The role of small fiber dysfunction in some types of ...

    Abstract Purpose of review: This article provides core information on the clinical neurophysiology techniques available for the investigation of disorders of the peripheral nervous system.
    Recent findings: The role of small fiber dysfunction in some types of polyneuropathy is being increasingly appreciated, and neurophysiologic techniques for evaluating the autonomic components of peripheral axons have enhanced our understanding of small fiber dysfunction.
    Summary: The principles of nerve conduction studies and needle EMG are presented in this article, along with the patterns of abnormality encountered in patients with polyneuropathy due to large and small fiber involvement.
    MeSH term(s) Electrodiagnosis/methods ; Electromyography/methods ; Humans ; Neural Conduction ; Polyneuropathies/diagnosis
    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1538-6899
    ISSN (online) 1538-6899
    DOI 10.1212/CON.0000000000000521
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Metformin and GDF15: where are we now?

    Kincaid, John W R / Coll, Anthony P

    Nature reviews. Endocrinology

    2022  Volume 19, Issue 1, Page(s) 6–7

    MeSH term(s) Humans ; Metformin/therapeutic use ; Growth Differentiation Factor 15
    Chemical Substances Metformin (9100L32L2N) ; GDF15 protein, human ; Growth Differentiation Factor 15
    Language English
    Publishing date 2022-10-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2489381-X
    ISSN 1759-5037 ; 1759-5029
    ISSN (online) 1759-5037
    ISSN 1759-5029
    DOI 10.1038/s41574-022-00764-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: NAD metabolism in aging and cancer.

    Kincaid, John Wr / Berger, Nathan A

    Experimental biology and medicine (Maywood, N.J.)

    2020  Volume 245, Issue 17, Page(s) 1594–1614

    Abstract: Impact statement: NAD is a central metabolite connecting energy balance and organismal growth with genomic integrity and function. It is involved in the development of malignancy and has a regulatory role in the aging process. These processes are ... ...

    Abstract Impact statement: NAD is a central metabolite connecting energy balance and organismal growth with genomic integrity and function. It is involved in the development of malignancy and has a regulatory role in the aging process. These processes are mediated by a diverse series of enzymes whose common focus is either NAD's biosynthesis or its utilization as a redox cofactor or enzyme substrate. These enzymes include dehydrogenases, cyclic ADP-ribose hydrolases, mono(ADP-ribosyl)transferases, poly(ADP-ribose) polymerases, and sirtuin deacetylases. This article describes the manifold pathways that comprise NAD metabolism and promotes an increased awareness of how perturbations in these systems may be important in disease prevention and/or progression.
    MeSH term(s) Aging/metabolism ; Animals ; Humans ; NAD/biosynthesis ; NAD/chemistry ; NAD/metabolism ; Neoplasms/metabolism ; Neurodegenerative Diseases/pathology ; Oxidation-Reduction ; Poly Adenosine Diphosphate Ribose/metabolism
    Chemical Substances NAD (0U46U6E8UK) ; Poly Adenosine Diphosphate Ribose (26656-46-2)
    Language English
    Publishing date 2020-06-05
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.1177/1535370220929287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Microbiome of Bacterially Impaired Watersheds: Distribution of Potential Bacterial Pathogens

    Kincaid, John C. / Owen, Marc R. / Pavlowsky, Robert T. / Mirza, Babur S.

    Diversity. 2022 Jan. 29, v. 14, no. 2

    2022  

    Abstract: Bacterial impairment of freshwater systems is a commonly studied global problem. However, studies on the relative distribution of bacterial pathogens in different impaired aquatic systems have been limited. Frequently, impaired freshwater systems are ... ...

    Abstract Bacterial impairment of freshwater systems is a commonly studied global problem. However, studies on the relative distribution of bacterial pathogens in different impaired aquatic systems have been limited. Frequently, impaired freshwater systems are classified by the presence of fecal indicator bacteria (FIB) and the identification of sources of fecal contamination through microbial source tracking. In this study, we assessed the relative abundance of DNA sequences related to potential human bacterial pathogens along with human fecal indicator bacteria in three impaired watersheds. These watersheds consistently showed a high abundance of FIB for the past several years. Using Illumina paired-end DNA sequencing of 16S rRNA gene amplicons, we observed variation in the relative distribution of DNA sequences related to Legionellaceae, Enterobacteriaceae and Bacteroidaceae families across different sites. We identified potential hotspots sites in these impaired water systems, which showed a relatively high abundance of pathogen-related DNA sequences. This study demonstrates the significance of Next-Gen DNA sequencing for the initial screening of waterborne pathogens and the identification of high-risk sites for preferential remediation efforts in impaired water systems. Secondly, the frequent temporal monitoring of specifically identified pathogens that are in high abundance in a watershed can help in the accurate prediction and prevention of disease outbreaks.
    Keywords Bacteroidaceae ; Enterobacteriaceae ; Legionellaceae ; disease prevention ; freshwater ; genes ; humans ; microbiome ; prediction ; remediation ; watersheds
    Language English
    Dates of publication 2022-0129
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518137-3
    ISSN 1424-2818
    ISSN 1424-2818
    DOI 10.3390/d14020096
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Federalism and the COVID-19 crisis in the United States of America

    Kincaid, John / Leckrone, J. Wesley

    Revista "Cuadernos Manuel Giménez Abad", ISSN 2254-4445, Nº. 19, 2020, pags. 48-49

    2020  

    Keywords covid19
    Language English
    Publishing country es
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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