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  1. Article ; Online: Impact of nutritional-behavioral and supervised exercise intervention following bariatric surgery: The BARI-LIFESTYLE randomized controlled trial.

    Jassil, Friedrich C / Carnemolla, Alisia / Kingett, Helen / Doyle, Jacqueline / Kirk, Amy / Lewis, Neville / Montagut, Gemma / Marvasti, Parastou / Boniface, David / Brown, Adrian / Chaiyasoot, Kusuma / Zakeri, Roxanna / Mok, Jessica / Devalia, Kalpana / Parmar, Chetan / Batterham, Rachel L

    Obesity (Silver Spring, Md.)

    2023  Volume 31, Issue 8, Page(s) 2031–2042

    Abstract: Objective: The study's aim was to investigate the impact of a 12-month adjunctive lifestyle intervention on weight loss and health outcomes after bariatric surgery.: Methods: A total of 153 participants (78.4% females; mean [SD], age 44.2 [10.6] ... ...

    Abstract Objective: The study's aim was to investigate the impact of a 12-month adjunctive lifestyle intervention on weight loss and health outcomes after bariatric surgery.
    Methods: A total of 153 participants (78.4% females; mean [SD], age 44.2 [10.6] years; BMI 42.4 [5.7] kg/m
    Results: Longitudinal analysis of the entire cohort showed significant reductions in body weight, fat mass, fat-free mass, and bone mineral density at the total hip, femoral neck, and lumbar spine (all p < 0.001). The 6-minute walk test, sit-to-stand test, health-related quality of life, and depressive symptomatology improved significantly (all p < 0.001). The time spent in moderate-to-vigorous physical activity and sedentary behavior remained the same as before surgery (both p > 0.05). There was no significant difference in the primary outcome between the intervention versus control (20.4% vs. 21.2%; mean difference = -0.8%; 95% CI: -2.8 to 1.1; p > 0.05) and no between-group differences in secondary outcomes.
    Conclusions: An adjunctive lifestyle program implemented immediately after surgery had no favorable impact upon weight loss and health outcomes.
    MeSH term(s) Female ; Humans ; Adult ; Male ; Quality of Life ; Life Style ; Bariatric Surgery ; Weight Loss ; Exercise Therapy
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2230457-5
    ISSN 1930-739X ; 1071-7323 ; 1930-7381
    ISSN (online) 1930-739X
    ISSN 1071-7323 ; 1930-7381
    DOI 10.1002/oby.23814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4061: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 87: Show issues

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  2. Article ; Online: Patients' views and experiences of live supervised tele-exercise classes following bariatric surgery during the COVID-19 pandemic: The BARI-LIFESTYLE qualitative study.

    Jassil, Friedrich C / Richards, Rebecca / Carnemolla, Alisia / Lewis, Neville / Montagut-Pino, Gemma / Kingett, Helen / Doyle, Jacqueline / Kirk, Amy / Brown, Adrian / Chaiyasoot, Kusuma / Devalia, Kalpana / Parmar, Chetan / Batterham, Rachel L

    Clinical obesity

    2021  Volume 12, Issue 2, Page(s) e12499

    Abstract: The BARI-LIFESTYLE trial is a randomized controlled trial evaluating the efficacy of a post-surgery nutritional and behavioural tele-counselling, and supervised exercise programme to maximize the health benefits of bariatric surgery. Due to the ... ...

    Abstract The BARI-LIFESTYLE trial is a randomized controlled trial evaluating the efficacy of a post-surgery nutritional and behavioural tele-counselling, and supervised exercise programme to maximize the health benefits of bariatric surgery. Due to the coronavirus disease 2019 (COVID-19) pandemic, the in-person supervised exercise component had to be converted to remote tele-exercise. However, patients' acceptability of this method of exercise provision is unknown. Between 3 and 6 months following bariatric surgery, 13 adults participated in weekly, structured, 60-min supervised exercise classes delivered via Zoom by a trained exercise therapist. A total of 12 participants (n = 8 female), with a mean age of 46.3 (range 33-63) years, who had undergone either sleeve gastrectomy (n = 8) or Roux-en-Y gastric bypass (n = 4) surgery, participated in one-to-one semi-structured interviews following the tele-exercise classes. Interviews were audio-recorded, transcribed verbatim and analysed using thematic analysis. Participants described how the tele-exercise classes helped them to cope with the changes to their lives brought about by the COVID-19 pandemic. Participants found the tele-exercise schedule, content and intensity to be acceptable, and were satisfied with the privacy, security and safety of the technology and classes. Professional supervision and guidance from an exercise therapist were described as central to the tele-exercise provision. Importantly, participation in the tele-exercise provided physical, emotional and social benefits. Few participants reported barriers to participation. Overall, the tele-exercise classes were deemed acceptable and compared favourably to in-person exercise classes.
    MeSH term(s) Adult ; Bariatric Surgery ; COVID-19/epidemiology ; Female ; Humans ; Life Style ; Middle Aged ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-11-28
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2625816-X
    ISSN 1758-8111 ; 1758-8103
    ISSN (online) 1758-8111
    ISSN 1758-8103
    DOI 10.1111/cob.12499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6918: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Is Pre-operation Social Connectedness Associated with Weight Loss up to 2 Years Post Bariatric Surgery?

    Tymoszuk, Urszula / Kumari, Meena / Pucci, Andrea / Cheung, Wui Hang / Kirk, Amy / Tschiala, Anita / Carr-Rose, Kayon / Kingett, Helen / Doyle, Jacqueline / Jenkinson, Andrew / Hashemi, Majid / Adamo, Marco / Elkalaawy, Mohamed / Stafford, Mai / Batterham, Rachel L

    Obesity surgery

    2018  Volume 28, Issue 11, Page(s) 3524–3530

    Abstract: Background: To date, little attention has been paid to supportive relationships as factors contributing to weight loss from bariatric surgery.: Material and methods: This prospective study examined whether total percentage weight loss (%TWL) at 3, 12 ...

    Abstract Background: To date, little attention has been paid to supportive relationships as factors contributing to weight loss from bariatric surgery.
    Material and methods: This prospective study examined whether total percentage weight loss (%TWL) at 3, 12 and 24 months post-surgery varies by distinct aspects of pre-surgery social support (received emotional and practical support and contact with friends and family) in a sample of bariatric surgery candidates (n = 182). These associations were tested with linear regression models adjusted for gender, age, ethnicity, employment status, self-esteem, mastery and time elapsed since the day of surgery.
    Results: One hundred fifty-four participants underwent a bariatric procedure, and all but seven provided weight loss data at least at one occasion. Emotional support and contact with friends were positively associated with %TWL at 3, 12 and 24 months, and the magnitude of these associations was large. For instance, in the fully adjusted models, %TWL at 24 months increased by 2.36% (SE 1.17, p = 0.048) with each increase of one standard deviation in emotional support and was higher by 9.23% (SE 4.31, p = 0.035) for participants who reported seeing 1-5 friends per month compared with those who saw none. There was some evidence for a positive association between practical support and %TWL at 3 and 12 months post-surgery.
    Conclusion: Supportive relationships are important contributors to weight loss from bariatric surgery. If replicated in future studies, these findings could inform clinical care and interventions aimed at improving support systems of bariatric surgery candidates.
    MeSH term(s) Bariatric Surgery/statistics & numerical data ; Humans ; Obesity, Morbid/epidemiology ; Obesity, Morbid/psychology ; Obesity, Morbid/surgery ; Prospective Studies ; Social Support ; Weight Loss/physiology
    Language English
    Publishing date 2018-06-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-018-3378-6
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3381: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Protocol for a 1-year prospective, longitudinal cohort study of patients undergoing Roux-en-Y gastric bypass and sleeve gastrectomy: the BARI-LIFESTYLE observational study.

    Jassil, Friedrich C / Carnemolla, Alisia / Kingett, Helen / Paton, Bruce / O'Keeffe, Aidan G / Doyle, Jacqueline / Morris, Stephen / Lewis, Neville / Kirk, Amy / Pucci, Andrea / Chaiyasoot, Kusuma / Batterham, Rachel L

    BMJ open

    2018  Volume 8, Issue 3, Page(s) e020659

    Abstract: Introduction: Roux-en-Y gastric bypass and sleeve gastrectomy are the two most common bariatric surgery performed in the UK that result in comparable weight loss and remission of obesity-associated comorbidities. However, there is a paucity of studies ... ...

    Abstract Introduction: Roux-en-Y gastric bypass and sleeve gastrectomy are the two most common bariatric surgery performed in the UK that result in comparable weight loss and remission of obesity-associated comorbidities. However, there is a paucity of studies examining the impact of these procedures on body composition, physical activity levels, sedentary behaviour, physical function and strength, dietary intake, health-related quality of life and costs.
    Methods and analysis: The BARI-LIFESTYLE observational study is a 1-year prospective, longitudinal cohort study within a real-world routine clinical care setting aiming to recruit 100 patients with severe obesity undergoing either primary Roux-en-Y gastric bypass or sleeve gastrectomy from two bariatric centres in London, UK. Participants will be followed up four times during the study period; presurgery baseline (T0) and at 3 (T1), 6 (T2) and 12 months (T3) postsurgery. In addition to the standard follow-up investigations, assessments including dual-energy X-ray absorptiometry scan, bioelectric impedance analysis, 6 min walk test, sit-to-stand test and handgrip test will be undertaken together with completion of questionnaires. Physical activity levels and sedentary behaviour will be assessed using accelerometer, and dietary intake will be recorded using a 3-day food diary. Outcome measures will include body weight, body fat mass, lean muscle mass, bone mineral density, physical activity levels, sedentary behaviour, physical function and strength, dietary intake, health-related quality of life, remission of comorbidities, healthcare resource utilisation and costs.
    Ethics and dissemination: This study has been reviewed and given a favourable ethical opinion by London-Dulwich Research Ethics Committee (17/LO/0950). The results will be presented to stakeholder groups locally, nationally and internationally and published in peer-reviewed medical journals. The lay-person summary of the findings will be published on the Centre for Obesity Research, University College London website (http://www.ucl.ac.uk/obesity).
    MeSH term(s) Absorptiometry, Photon ; Adult ; Aged ; Body Composition ; Body Weight ; Exercise ; Female ; Gastrectomy/methods ; Gastric Bypass/methods ; Humans ; Life Style ; Longitudinal Studies ; Male ; Middle Aged ; Obesity, Morbid/surgery ; Prospective Studies ; Quality of Life ; Sedentary Behavior ; Young Adult
    Language English
    Publishing date 2018-03-16
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2017-020659
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  5. Article: A case of severe anorexia, excessive weight loss and high peptide YY levels after sleeve gastrectomy.

    Pucci, Andrea / Cheung, Wui Hang / Jones, Jenny / Manning, Sean / Kingett, Helen / Adamo, Marco / Elkalaawy, Mohamed / Jenkinson, Andrew / Finer, Nicholas / Doyle, Jacqueline / Hashemi, Majid / Batterham, Rachel L

    Endocrinology, diabetes & metabolism case reports

    2015  Volume 2015, Page(s) 150020

    Abstract: Unlabelled: Sleeve gastrectomy (SG) is the second most commonly performed bariatric procedure worldwide. Altered circulating gut hormones have been suggested to contribute post-operatively to appetite suppression, decreased caloric intake and weight ... ...

    Abstract Unlabelled: Sleeve gastrectomy (SG) is the second most commonly performed bariatric procedure worldwide. Altered circulating gut hormones have been suggested to contribute post-operatively to appetite suppression, decreased caloric intake and weight reduction. In the present study, we report a 22-year-old woman who underwent laparoscopic SG for obesity (BMI 46 kg/m(2)). Post-operatively, she reported marked appetite reduction, which resulted in excessive weight loss (1-year post-SG: BMI 22 kg/m(2), weight loss 52%, >99th centile of 1-year percentage of weight loss from 453 SG patients). Gastrointestinal (GI) imaging, GI physiology/motility studies and endoscopy revealed no anatomical cause for her symptoms, and psychological assessments excluded an eating disorder. Despite nutritional supplements and anti-emetics, her weight loss continued (BMI 19 kg/m(2)), and she required nasogastric feeding. A random gut hormone assessment revealed high plasma peptide YY (PYY) levels. She underwent a 3 h meal study following an overnight fast to assess her subjective appetite and circulating gut hormone levels. Her fasted nausea scores were high, with low hunger, and these worsened with nutrient ingestion. Compared to ten other post-SG female patients, her fasted circulating PYY and nutrient-stimulated PYY and active glucagon-like peptide 1 (GLP1) levels were markedly elevated. Octreotide treatment was associated with suppressed circulating PYY and GLP1 levels, increased appetite, increased caloric intake and weight gain (BMI 22 kg/m(2) after 6 months). The present case highlights the value of measuring gut hormones in patients following bariatric surgery who present with anorexia and excessive weight loss and suggests that octreotide treatment can produce symptomatic relief and weight regain in this setting.
    Learning points: Roux-en-Y gastric bypass and SG produce marked sustained weight reduction. However, there is a marked individual variability in this reduction, and post-operative weight loss follows a normal distribution with extremes of 'good' and 'poor' response.Profound anorexia and excessive weight loss post-SG may be associated with markedly elevated circulating fasted PYY and post-meal PYY and GLP1 levels.Octreotide treatment can produce symptomatic relief and weight regain for post-SG patients that have an extreme anorectic and weight loss response.The present case highlights the value of measuring circulating gut hormone levels in patients with post-operative anorexia and extreme weight loss.
    Language English
    Publishing date 2015-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2785530-2
    ISSN 2052-0573
    ISSN 2052-0573
    DOI 10.1530/EDM-15-0020
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  6. Article ; Online: Feasibility and Impact of a Combined Supervised Exercise and Nutritional-Behavioral Intervention following Bariatric Surgery: A Pilot Study.

    Jassil, Friedrich C / Manning, Sean / Lewis, Neville / Steinmo, Siri / Kingett, Helen / Lough, Fiona / Pucci, Andrea B F / Cheung, W H / Finer, Nicholas / Walker, Judith / Doyle, Jaqueline / Batterham, Rachel L

    Journal of obesity

    2015  Volume 2015, Page(s) 693829

    Abstract: Background: Lifestyle intervention programs after bariatric surgery have been suggested to maximise health outcomes. This pilot study aimed to investigate the feasibility and impact of an 8-week combined supervised exercise with nutritional-behavioral ... ...

    Abstract Background: Lifestyle intervention programs after bariatric surgery have been suggested to maximise health outcomes. This pilot study aimed to investigate the feasibility and impact of an 8-week combined supervised exercise with nutritional-behavioral intervention following Roux-en-Y gastric bypass and sleeve gastrectomy.
    Methods: Eight female patients (44 ± 8 years old, BMI = 38.5 ± 7.2 kg m(-2)) completed the program. Before and after intervention, anthropometric measures, six-minute walk test (6MWT), physical activity level, eating behavior, and quality of life (QoL) were assessed. Percentage weight loss (%WL) outcomes were compared with a historical matched control group.
    Results: The program significantly improved functional capacity (mean increment in 6MWT was 127 ± 107 meters, p = 0.043), increased strenuous intensity exercise (44 ± 49 min/week, p = 0.043), increased consumption of fruits and vegetables (p = 0.034), reduced consumption of ready meals (p = 0.034), and improved "Change in Health" in QoL domain (p = 0.039). The intervention group exhibited greater %WL in the 3-12-month postsurgery period compared to historical controls, 12.2 ± 7.5% versus 5.1 ± 5.4%, respectively (p = 0.027).
    Conclusions: Lifestyle intervention program following bariatric surgery is feasible and resulted in several beneficial outcomes. A large randomised control trial is now warranted.
    MeSH term(s) Adult ; Behavior Therapy/methods ; Combined Modality Therapy ; Exercise ; Feasibility Studies ; Female ; Gastrectomy ; Gastric Bypass ; Humans ; Nutrition Therapy/methods ; Obesity, Morbid/prevention & control ; Obesity, Morbid/psychology ; Obesity, Morbid/therapy ; Pilot Projects ; Quality of Life ; Risk Reduction Behavior ; Treatment Outcome ; Weight Loss
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2573566-4
    ISSN 2090-0716 ; 2090-0708
    ISSN (online) 2090-0716
    ISSN 2090-0708
    DOI 10.1155/2015/693829
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