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  1. Article ; Online: Preinjury Functional Independence is not Associated with Discharge Location in Older Trauma Patients.

    Holler, Emma / Meagher, Ashley D / Ortiz, Damaris / Mohanty, Sanjay / Newnum, America / Perkins, Anthony / Gao, Sujuan / Kinnaman, Gabriel / Boustani, Malaz / Zarzaur, Ben

    The Journal of surgical research

    2021  Volume 266, Page(s) 413–420

    Abstract: Background: The purpose of this study was to evaluate the association between pre-injury Katz Index of Independence in Activities of Daily Living (Katz ADL) functional status and discharge to a facility in non-neurologically injured older trauma ... ...

    Abstract Background: The purpose of this study was to evaluate the association between pre-injury Katz Index of Independence in Activities of Daily Living (Katz ADL) functional status and discharge to a facility in non-neurologically injured older trauma patients.
    Methods: Data were obtained from 207 patients in the Trauma Medical Home study cohort. Multivariable logistic regression was performed to identify factors associated with non-home discharge.
    Results: Average patient age was 67.9 (SD 11.1). Patients were predominantly white (89.4%) and female (52.2%) with a median ISS of 11 (IQR 9-14). The most common mechanism of injury was fall (48.3%), followed by motor vehicle crash (41.1%). Nearly all patients (94.7%) reported independence in activities of daily living prior to hospitalization for injury. Discharge disposition varied, 51.7% of patients were discharged home, 37.7% to subacute rehabilitation, 10.1% to acute rehabilitation and 0.5% to long-term acute care. There was no relationship between pre-injury independence and likelihood of discharge home (P = 0.1331). Age (P < 0.0001), BMI (P = 0.0002), Charlson comorbidity score of 3 or greater (P = 0.0187), being single (P = 0.0077), ISS ≥ 16 (P = 0.0075) and being female with self-reported symptoms of anxiety and/or depression over the past two weeks (P = 0.0092) were associated with significantly greater odds of non-home discharge.
    Conclusions: Pre-injury Katz ADL is not associated with discharge disposition, though other significantly associated factors were identified. It is imperative that discussions regarding discharge disposition are initiated early during acute hospitalization. Trauma programs could potentially benefit from implementing an inpatient intervention focused on building coping skills for older patients exhibiting symptoms of anxiety or depression.
    MeSH term(s) Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Functional Status ; Humans ; Male ; Middle Aged ; Patient Discharge/statistics & numerical data ; Wounds and Injuries/rehabilitation
    Language English
    Publishing date 2021-06-05
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 80170-7
    ISSN 1095-8673 ; 0022-4804
    ISSN (online) 1095-8673
    ISSN 0022-4804
    DOI 10.1016/j.jss.2021.04.029
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    Zs.A 178: Show issues Location:
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  2. Article ; Online: Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease 2019.

    Maatman, Thomas K / Jalali, Farid / Feizpour, Cyrus / Douglas, Anthony / McGuire, Sean P / Kinnaman, Gabriel / Hartwell, Jennifer L / Maatman, Benjamin T / Kreutz, Rolf P / Kapoor, Rajat / Rahman, Omar / Zyromski, Nicholas J / Meagher, Ashley D

    Critical care medicine

    2020  Volume 48, Issue 9, Page(s) e783–e790

    Abstract: Objectives: The aim of this study was to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development.: Design: An ... ...

    Abstract Objectives: The aim of this study was to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development.
    Design: An observational study that identified patients with severe coronavirus disease 2019 between March 12, 2020, and March 31, 2020. Data reported are those available through May 6, 2020.
    Setting: A multicenter study including three Indianapolis area academic hospitals.
    Patients: Two-hundred forty consecutive patients with confirmed severe acute respiratory syndrome coronavirus 2 infection were admitted to one of three hospitals. One-hundred nine critically ill coronavirus disease 2019 patients admitted to the ICU were included in the analysis.
    Interventions: All patients received routine subcutaneous chemical venous thromboembolism prophylaxis.
    Measurements and main results: The primary outcome of this study was to determine the frequency of venous thromboembolism and the degree of inflammatory and coagulation marker elevation associated with venous thromboembolism development. Descriptive statistics outlined the frequency of venous thromboembolism at any time during severe coronavirus disease 2019. Clinical course and laboratory metrics were compared between patients that developed venous thromboembolism and patients that did not develop venous thromboembolism. Hypercoagulable thromboelastography was defined as two or more hypercoagulable parameters.
    Main results: One-hundred nine patients developed severe coronavirus disease 2019 requiring ICU care. The mean (± SD) age was 61 ± 16 years and 57% were male. Seventy-five patients (69%) were discharged home, 7 patients (6%) remain in the hospital, and 27 patients (25%) died. Venous thromboembolism was diagnosed in 31 patients (28%) 8 ± 7 days after hospital admission, including two patients diagnosed with venous thromboembolism at presentation to the hospital. Elevated admission D-dimer and peak D-dimer were associated with venous thromboembolism development (p < 0.05). D-dimer greater than 2,600 ng/mL predicted venous thromboembolism with an area under the receiver operating characteristic curve of 0.760 (95% CI, 0.661-0.858; p < 0.0001), sensitivity of 89.7%, and specificity of 59.5%. Twelve patients (11%) had thromboelastography performed and 58% of these patients had a hypercoagulable study. The calculated coagulation index was hypercoagulable in 50% of patients with thromboelastography.
    Conclusions: These data show that coronavirus disease 2019 results in a hypercoagulable state. Routine chemical venous thromboembolism prophylaxis may be inadequate in preventing venous thromboembolism in severe coronavirus disease 2019.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anticoagulants/therapeutic use ; Betacoronavirus ; Biomarkers/blood ; COVID-19 ; Comorbidity ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/mortality ; Critical Illness ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/mortality ; SARS-CoV-2 ; Thrombelastography ; Thrombophilia/diagnosis ; Thrombophilia/drug therapy ; Thrombophilia/etiology ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology ; Venous Thromboembolism/prevention & control ; Young Adult ; COVID-19 Drug Treatment
    Chemical Substances Anticoagulants ; Biomarkers
    Keywords covid19
    Language English
    Publishing date 2020-05-19
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000004466
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  3. Article: Microwave-induced rapid hydrolysis of acetaminophen and its conjugates in urine for emergency toxicological screen.

    Dasgupta, A / Kinnaman, G

    Clinical chemistry

    1993  Volume 39, Issue 11 Pt 1, Page(s) 2349–2350

    MeSH term(s) Acetaminophen/urine ; Emergencies ; Humans ; Hydrolysis ; Microwaves ; Toxicology
    Chemical Substances Acetaminophen (362O9ITL9D)
    Language English
    Publishing date 1993-11
    Publishing country England
    Document type Letter
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
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  4. Article: Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease 2019

    Maatman, Thomas K / Jalali, Farid / Feizpour, Cyrus / Douglas, Anthony / McGuire, Sean P / Kinnaman, Gabriel / Hartwell, Jennifer L / Maatman, Benjamin T / Kreutz, Rolf P / Kapoor, Rajat / Rahman, Omar / Zyromski, Nicholas J / Meagher, Ashley D

    Crit Care Med

    Abstract: OBJECTIVES: The aim of this study was to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development. DESIGN: An ... ...

    Abstract OBJECTIVES: The aim of this study was to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development. DESIGN: An observational study that identified patients with severe coronavirus disease 2019 between March 12, 2020, and March 31, 2020. Data reported are those available through May 6, 2020. SETTING: A multicenter study including three Indianapolis area academic hospitals. PATIENTS: Two-hundred forty consecutive patients with confirmed severe acute respiratory syndrome coronavirus 2 infection were admitted to one of three hospitals. One-hundred nine critically ill coronavirus disease 2019 patients admitted to the ICU were included in the analysis. INTERVENTIONS: All patients received routine subcutaneous chemical venous thromboembolism prophylaxis. MEASUREMENTS AND MAIN RESULTS: The primary outcome of this study was to determine the frequency of venous thromboembolism and the degree of inflammatory and coagulation marker elevation associated with venous thromboembolism development. Descriptive statistics outlined the frequency of venous thromboembolism at any time during severe coronavirus disease 2019. Clinical course and laboratory metrics were compared between patients that developed venous thromboembolism and patients that did not develop venous thromboembolism. Hypercoagulable thromboelastography was defined as two or more hypercoagulable parameters. MAIN RESULTS: One-hundred nine patients developed severe coronavirus disease 2019 requiring ICU care. The mean (± SD) age was 61 ± 16 years and 57% were male. Seventy-five patients (69%) were discharged home, 7 patients (6%) remain in the hospital, and 27 patients (25%) died. Venous thromboembolism was diagnosed in 31 patients (28%) 8 ± 7 days after hospital admission, including two patients diagnosed with venous thromboembolism at presentation to the hospital. Elevated admission D-dimer and peak D-dimer were associated with venous thromboembolism development (p < 0.05). D-dimer greater than 2,600 ng/mL predicted venous thromboembolism with an area under the receiver operating characteristic curve of 0.760 (95% CI, 0.661-0.858; p < 0.0001), sensitivity of 89.7%, and specificity of 59.5%. Twelve patients (11%) had thromboelastography performed and 58% of these patients had a hypercoagulable study. The calculated coagulation index was hypercoagulable in 50% of patients with thromboelastography. CONCLUSIONS: These data show that coronavirus disease 2019 results in a hypercoagulable state. Routine chemical venous thromboembolism prophylaxis may be inadequate in preventing venous thromboembolism in severe coronavirus disease 2019.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #380791
    Database COVID19

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  5. Article: Analytical performance evaluation of EMIT II monoclonal amphetamine/methamphetamine assay: more specificity than EMIT d.a.u. monoclonal amphetamine/methamphetamine assay.

    Dasgupta, A / Saldana, S / Kinnaman, G / Smith, M / Johansen, K

    Clinical chemistry

    1993  Volume 39, Issue 1, Page(s) 104–108

    Abstract: We evaluated a new EMIT II monoclonal amphetamine/methamphetamine assay for screening human urine by comparing it with the EMIT d.a.u. monoclonal amphetamine/methamphetamine assay and a fluorescence polarization assay. The EMIT II assay has a cutoff of 1 ...

    Abstract We evaluated a new EMIT II monoclonal amphetamine/methamphetamine assay for screening human urine by comparing it with the EMIT d.a.u. monoclonal amphetamine/methamphetamine assay and a fluorescence polarization assay. The EMIT II assay has a cutoff of 1 mg/L d-methamphetamine. The EMIT II and EMIT d.a.u. assays were run on a BM/Hitachi 704 analyzer; for the fluorescence polarization assay we used a TDx analyzer. All EMIT II positive samples were also analyzed by the fluorescence polarization assay. We used gas chromatography/mass spectrometry (GC/MS) for confirmation of the presence of amphetamine or methamphetamine. Within-run CVs for the Level 1 (1 mg/L) and Level 2 (3 mg/L) calibrators for the EMIT II assay were 0.47% and 0.53%, respectively. Corresponding between-run CVs were 1.48% and 1.60%, respectively. Of the 1007 samples screened for amphetamines, 50 were positive by the EMIT d.a.u. assay; 21 samples (not a subset of the 50 samples) were positive by the EMIT II assay. However, 19 samples that tested positive by EMIT II also tested positive by the EMIT d.a.u. assay. Subsequent testing of the EMIT II positive samples by the fluorescence polarization assay detected in six positive samples. By means of chiral derivatization wer identified two specimens containing primarily l-isomers of amphetamine and methamphetamine. Sympathomimetic amines were identified in several of the samples not containing amphetamine or methamphetamine.
    MeSH term(s) Amphetamine/urine ; Antibodies, Monoclonal ; Enzyme Multiplied Immunoassay Technique/standards ; Enzyme Multiplied Immunoassay Technique/statistics & numerical data ; Fluorescence Polarization ; Gas Chromatography-Mass Spectrometry ; Humans ; Methamphetamine/urine ; Quality Control ; Reagent Kits, Diagnostic/standards ; Reagent Kits, Diagnostic/statistics & numerical data ; Substance Abuse Detection
    Chemical Substances Antibodies, Monoclonal ; Reagent Kits, Diagnostic ; Methamphetamine (44RAL3456C) ; Amphetamine (CK833KGX7E)
    Language English
    Publishing date 1993-01
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
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  6. Article: Absorption of therapeutic drugs by barrier gels in serum separator blood collection tubes. Volume- and time-dependent reduction in total and free drug concentrations.

    Dasgupta, A / Dean, R / Saldana, S / Kinnaman, G / McLawhon, R W

    American journal of clinical pathology

    1994  Volume 101, Issue 4, Page(s) 456–461

    Abstract: The stability of seven commonly monitored therapeutic drugs in serum was examined following storage in Vacutainer SST and Corvac serum separator blood collection tubes. Significant decreases (ranging from 5.9% to 64.5%) in the measured concentrations of ... ...

    Abstract The stability of seven commonly monitored therapeutic drugs in serum was examined following storage in Vacutainer SST and Corvac serum separator blood collection tubes. Significant decreases (ranging from 5.9% to 64.5%) in the measured concentrations of phenytoin, phenobarbital, lidocaine, quinidine, and carbamazepine were observed, as a function of both time and sample volume, when serum was stored in Vacutainer SST serum separator blood collection tubes. In contrast, measured concentrations of theophylline and salicylate did not change under identical specimen storage conditions. No significant changes in the concentrations of phenytoin, phenobarbital, carbamazepine, theophylline, quinidine, and salicylate were observed when serum was stored in Corvac serum separator blood collection tubes. Only serum lidocaine concentrations decreased (ranging from 31.5% to 72.6%, depending on sample volume) after storage in Corvac tubes for 24 hours. The apparent decreases in serum concentrations of therapeutic drugs in both Vacutainer SST and Corvac tubes were most pronounced when small volumes (200-500 microL) of serum remained in contact with the barrier gels for prolonged periods of time (> 2-6 hours). These decreases were due to absorption of drugs by the barrier gels, as demonstrated by the recovery of drugs following chemical extraction of the barrier gels with methanol. For phenytoin and phenobarbital, the reduction in total drug concentrations also resulted in a proportional decrease in free drug concentrations and was dependent on the extent of protein binding by the drug. None of the therapeutic drugs used in this study were adversely affected by prolonged storage in standard red top Vacutainer blood collection tubes without barrier gels. The data suggest that serum separator blood collection tubes should be used with extreme caution for therapeutic drug monitoring, particularly when reduced sample volumes or prolonged specimen storage may be required.
    MeSH term(s) Absorption ; Blood Preservation ; Blood Specimen Collection/methods ; Drug Stability ; Gels ; Humans ; Infant, Newborn ; Male ; Pharmaceutical Preparations/analysis ; Phenytoin/blood ; Protein Binding ; Time Factors
    Chemical Substances Gels ; Pharmaceutical Preparations ; Phenytoin (6158TKW0C5)
    Language English
    Publishing date 1994-04
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2944-0
    ISSN 1943-7722 ; 0002-9173
    ISSN (online) 1943-7722
    ISSN 0002-9173
    DOI 10.1093/ajcp/101.4.456
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  7. Article: VIII. An Experimental Research into the Temperature Relationship existing in Shock.

    Kinnaman, G C

    Annals of surgery

    1903  Volume 38, Issue 6, Page(s) 843–877

    Language English
    Publishing date 1903-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
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    ISSN 0003-4932
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  8. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Nepogodiev, D / Bhangu, A / Glasbey, JC / Li, E / Omar, OM / Simoes, JFF / Abbott, TEF / Alser, O / Arnaud, AP / Bankhead-Kendall, BK / Breen, KA / Cunha, MF / Davidson, GH / Di Saverio, S / Gallo, G / Griffiths, EA / Gujjuri, RR / Hutchinson, PJ / Kaafarani, HMA /
    Lederhuber, H / Löffler, MW / Mashbari, HN / Minaya-Bravo, A / Morton, DG / Moszkowicz, D / Pata, F / Tsoulfas, G / Venn, ML / Cox, D / Roslani, AC / Alakaloko, F / de Vries, JPPM / Aaraj, MA / Abbott, SJ / Abdalla, MOM / Abdelaal, AS / Ademuyiwa, AO / Aherne, TM / Ali, OM / Alkadeeki, GZ / Almeida, AC / Alrahawy, MM / Ambler, GK / Alameer, E / Andreani, SM / De Andrés-Asenjo, B / Antonanzas, LL / Aoun, SG / Ashoush, FM / Augestad, KM / Avellana, RB / Ayeni, FA / Ayorinde, JOO / Babu, BH / Baig, MMAS / Bajomo, OM / Baker, OJ / Baker, MP / Baldwin, AJ / Ban, VS / Baron, RD / Barranquero, AG / Barry, CP / DI Bartolomeo, A / Bass, GA / Bath, MF / Batjer, HH / Beamish, AJ / Belgaumkar, AP / Bence, MN / Benson, RA / Bernal-Sprekelsen, JC / Bhama, AR / Bhavaraju, AV / Biffl, WL / Blundell, CM / Boddy, AP / Borgstein, ABJ / Bosanquet, DC / Bosch, KD / Bouhuwaish, AEM / Bozkurt, MA / Brathwaite, CEM / Brown, BC / Brown, OD / Brown, AK / Buarque, IL / Bueno-Ca nones, AD / Bulugma, MR / Burke, JR / Byrne, MHV / Cagigal-Ortega, EP / Callcut, RA / DI Candido, F / Canova, ME / Carlos, WJ / Caruana, EJ / Cato, LD / Catton, AB / Ceretti, AP / Chase, TJG / Chiara, FD / Chowdhury, AH / Chung, EA / Cicerchia, PM / Clough, ECS / Coleman, NL / Collins, CG / Collins, ML / Colonna, ET / Comini, LV / Coughlin, PA / Cruzado, LFG / Davidson, BR / Davies, RJ / Davies, EJ / Davis, NF / Dawson, BE / Dean, BJF / Delgado, MGC / Diaz, JJ / Dickson, KE / Diez-Alonso, MM / Dixon, JR / Doe, MJ / Drake, TD / Drake, FT / Duffy, JP / Dunne, DFJ / Dunne, NJM / Durán-Mu noz-Cruzado, VM / Durst, AZE / Eardley, NJ / Edwards, JG / Elfallal, AH / Elfiky, MMA / Elliott, JA / Emile, SH / Emslie, KM / Endorf, FW / Engel, JL / Enjuto, DT / Etchill, EW / Evans, JP / Fahey, BA / Faria, CS / Feo, CV / Ferguson, HJM / Fernandez, BD / Fernandez, AG / Fernández, AJ / Fernández-Pacheco, BC / Fitzgerald, JE / Fonsi, GB / Font, RF / Fowler, AL / Fretwell, KR / Fructuoso, LS / Fusai, GK / Garcia, MH / Garcia-Ure na, MA / Gill, CK / Gisbertz, SS / Del Giudice, R / Giuffrida, MC / Di Giuseppe, M / Gómez, MF / Guariglia, CA / Hainsworth, AJ / Hall, BJ / Hall, JRW / Hammond, JS / Haqqani, MH / Harrison, EM / Hazelton, JP / van Heinsbergen, M / Hill, ADK / Hing, CB / Hirji, SA / Ho, MWS / Holbrook, CM / Holme, TJ / Hopkins, JC / Hopkinson, DN / Hossain, FS / Hudson, VE / Hughes, JL / Hwang, ES / Ibrahim, MAH / Isolani, SM / Jenkinson, MD / Jenny, HE / Jeyaretna, DS / Jones, RP / Jones, AP / Jonker, PKC / Jönsson, ML / Joyce, DP / Kalkwarf, KJ / Kamarajah, SK / El Kassas, M / Kavanagh, DO / Keatley, JM / Khalefa, MA / Khan, JS / Kirmani, BH / Kisiel, AP / Kouris, SM / Kowal, MR / Labib, PL / Larkin, JO / Lauscher, JC / Leclercq, WKG / Ledesma, FSJ / Leite-Moreira, AM / Leung, EYL / Lewis, SE / Lima, MJA / Lin, DJ / Liu, HH / Lowery, AJ / Lozano, SM / Luney, CR / Maia, MMA / Mariani, NM / Marino, MV / Marra, AA / Marsh, CL / Martin, RCG / McCluney, SJ / McIntyre, RC / Mckay, SC / McKevitt, KL / Meagher, AD / Mehdi, MQ / Mehigan, BJ / Gonzalez-De Miguel, M / De Miguel-Ardevines, MC / Mills, SJ / Mohan, HM / Moir, JAG / Monson, JRT / Monteiro, JM / Montella, MT / Montesinos, CS / Morgom, MM / Moura, FS / Muguerza, JM / Murphy, SH / De Nardi, P / Naumann, DN / Neary, PC / Neely, DTA / Ng-Kamstra, JS / Ngu, AWT / Nguyen, TA / Nita, GE / Nunes, QM / Nygaard, RM / O’Meara, LB / O’Neill, JR / Okafor, BU / Olson, SA / Oo, AY / Ormazabal, PC / Osorio, AL / Pachl, MJ / Parry, JT / Patel, PK / Pérez-Sánchez, LE / Pevidal, AN / Pezzuto, AP / Philp, MM / Pinkney, TD / Pollok, JM / Povey, MG / Poza, AA / Rajgor, AD / Rao, JN / Raptis, DA / Rice, HE / Ridgway, PF / Rivas, AM / Rodriguez-Sanjuan, JC / Rogers, LJ / Da Roit, A / Rollett, RA / Romera, JL / Rooney, SM / Roxo, VI / Le Roy, B / Rubio, EE / Ruiz, CC / Ruiz, ML / Ryan, ÉJ / Saad, AR / Saeed, SA / Salama, HA / Salamah, AA / Sampietro, GM / Sarma, DR / Schaffer, KB / Schnitzbauer, AA / Scurrah, RJ / Serevina, OL / Serralheiro, PA / Sewards, JM / Shackcloth, MJ / Shaw, AV / Sheel, ARG / Sica, GS / De Simone, V / Singh, AA / Singh, RP / Skelly, BL / Smith, HG / Sohail, AH / Spalding, DR / Springford, LR / Ssentongo, AE / Steinkamp, PJ / Stevens, KA / Stewart, GD / Stylianides, NA / Sullivan, TBB / Taher, ASA / Tamimy, MS / Tang, AM / Tebala, GD / Tejero-Pintor, FJ / Thaha, MA / Thomas, AJ / De Toma, G / La Torre, F / Torres, AJ / Townshend, DN / Trout, IM / Tucker, SC / Ubhi, HK / Vega, VA / Velmahos, GC / Velopulos, CG / Viswanath, YKS / Vivas, AA / Wade, RG / Wadley, MS / Wall, JJS / Walters, AM / Warren, OJ / Weerasinghe, CK / Wilkin, RJW / Williams, KJ / Winter, SC / Wormald, JCR / Wright, FL / Xyda, SE / Young, AL / Youssef, MMG / Yousuf, FB / El Youzouri, H / Zappa, MA / Abate, E / Abdalaziz, H / Abdelkarim, M / Abdou, H / Aboelkassem-Ibrahim, A / Abuown, A / Acebes-Garcia, F / Acharya, M / Adamina, M / Addae-Boateng, E / Aftab, R / Agarwal, A / Aguilar, J / Ahmed, Y / Aitken, E / Al-Azzawi, M / Al-Embideen, 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del Pueblo, C / van Ramshorst, GH / De Salas, MM / De Souza, AC / Dolores Del Toro, M / Archer, JE / Odeh, A / Erridge, S / Salem, HK / Jones, GP / Gardner, A / Tripathi, SS / Gregg, A / Jeganathan, R / Siddique, MH / Lombardi, CP / Martin, B / Leo, CA / Dass, D / Di Franco, G / Jiao, LR / Mari, GM / Capitan-Morales, LC / Connelly, TM / Alanbuki, A / De Virgilio, A / Schilling, C / San Miguel Mendez, C / Kulkarni, G / Nizami, K / Walsh, S / Dean, H / Ruiz-Marin, M / Houston, R / Trompetto, M / Chrastek, D / Kouritas, V / Cannoletta, M / Rosato, F / Kaushal, MV / Costa, PM / Elkadi, HH / Johnstone, JR / Irvine, E / Alvarez, MR / Corbellini, C / Venkatesan, GS / Mateo-Sierra, O / Martínez-Pérez, C / Serrano González, J / Hernández Bartolomé, MÁ / Díaz Pérez, D / Gutiérrez Samaniego, M / Galindo Jara, P / Sharma, N / Smart, NJ / Keller, DS

    an international cohort study

    2020  

    Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

    Abstract Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
    Keywords covid19
    Language English
    Publisher Elsevier
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Nepogodiev D. / Bhangu A. / Glasbey J.C. / Li E. / Omar O.M. / Simoes J.F. / Abbott T.E. / Alser O. / Arnaud A.P. / Bankhead-Kendall B.K. / Breen K.A. / Cunha M.F. / Davidson G.H. / Di Saverio S. / Gallo G. / Griffiths E.A. / Gujjuri R.R. / Hutchinson P.J. / Kaafarani H.M. /
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G.S. / Mateo-Sierra O. / Martinez-Perez C. / Serrano Gonzalez J. / Hernandez Bartolome M.A. / Diaz Perez D. / Gutierrez Samaniego M. / Galindo Jara P. / Sharma N. / Smart N.J. / Keller D.S.

    an international cohort study

    2020  

    Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

    Abstract Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p<0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
    Keywords Adult ; Aged ; Betacoronavirus ; Coronavirus Infections ; Elective Surgical Procedures ; Emergency Medical Services ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia ; Viral ; Postoperative Complications ; Respiratory Tract Diseases ; Retrospective Studies ; Surgical Procedures ; Operative ; Young Adult ; covid19
    Subject code 610 ; 616
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Salomone, / Saverio, Di / Griffiths, / Ewen, A / Gujjuri, Rohan R / Hutchinson, Peter J / Kaafarani, Haytham MA / Lederhuber, Hans / Löffler, Markus W / Mashbari, Hassan N / Minaya-Bravo, Ana / Morton, Dion G / Moszkowicz, David / Pata, Francesco / Tsoulfas, George / Venn, Mary L / Cox, Daniel / Roslani, April C / Alakaloko, Felix /
    de Vries, Jean-Paul PM / Aaraj, Mahmoud A / Abbott, Tom EF / Abbott, Sarah J / Abdalla, Mutwakil OM / Abdelaal, Ahmed S / Ademuyiwa, Adesoji O / Aherne, Thomas M / Ali, Osman M / Alkadeeki, Ghadah Z / Almeida, Ana C / Alrahawy, Mahmoud M / Ambler, Graeme K / Alameer, Ehab / Andreani, Stefano M / De Andrés-Asenjo, Beatriz / Antonanzas, Leyre Lopez / Aoun, Salah G / Ashoush, Fouad M / Augestad, Knut Magne / Avellana, Rocio B / Ayeni, Funbi A / Ayorinde, John OO / Babu, Bheemanakone H / Baig, Mirza MAS / Bajomo, Oreoluwa M / Baker, Olivia J / Baker, Markus P / Baldwin, Alexander J / Ban, Vin Shen / Baron, Ryan D / Barranquero, Alberto G / Barry, Conor P / DI Bartolomeo, Alessandro / Bass, Gary A / Bath, Michael F / Batjer, H Hunt / Beamish, Andrew J / Belgaumkar, Ajay P / Bence, Matthew N / Benson, Ruth A / Bernal-Sprekelsen, Juan Carlos / Bhama, Anuradha R / Bhavaraju, Avi V / Biffl, Walter L / Blundell, Chris M / Boddy, Alexander P / Borgstein, Alexander BJ / Bosanquet, David C / Bosch, Karen D / Bouhuwaish, Ahmad EM / Bozkurt, Mehmet A / Brathwaite, Collin EM / Brown, Benjamin C / Brown, Oliver D / Brown, Allison K / Buarque, Igor Lima / Bueno-Cañones, Alejandro D / Bulugma, Mustafa R / Burke, Joshua R / Byrne, Matthew HV / Cagigal-Ortega, Elima P / Callcut, Rachael A / DI Candido, Francesca / Canova, Michaela E / Carlos, William J / Caruana, Edward J / Cato, Liam D / Catton, Andrew B / Ceretti, Andrea Pisani / Chase, Thomas JG / Chiara, Francesco Di / Chowdhury, Abeed H / Chung, Eric A / Cicerchia, Pierfranco M / Clough, Ethan CS / Coleman, Natasha L / Collins, Chris G / Collins, Michelle L / Colonna, Emily T / Comini, Lara V / Coughlin, Patrick A / Cruzado, Laura Fernández-Gomez / Davidson, Brian R / Davies, Richard J / Davies, Emma J / Davis, Niall F / Dawson, Brett E / Dean, Benjamin JF / Delgado, Maria Garcia-Conde / Diaz, Jose J / Dickson, Kathryn E / Diez-Alonso, Manuel M / Dixon, Jan R / Doe, Matthew J / Drake, Thomas D / Drake, Frederick T / Duffy, John P / Dunne, Declan FJ / Dunne, Naomi JM / Durán-Muñoz-Cruzado, Virginia M / Durst, Alexander ZE / Eardley, Nicola J / Edwards, John G / Elfallal, Ahmed H / Elfiky, Mahmoud MA / Elliott, Jessie A / Emile, Sameh H / Emslie, Katy M / Endorf, Frederick W / Engel, Jamie L / Enjuto, Diego T / Etchill, Eric W / Evans, Jonathan P / Fahey, Brian A / Faria, Carlos S / Feo, Carlo V / Ferguson, Henry JM / Fernandez, Beatriz Dieguez / Fernandez, Andres Garcia / Fernández, Antonio J / Fernández-Pacheco, Borja Camacho / Fitzgerald, J Edward / Fonsi, Giovanni B / Font, Roser Farré / Fowler, Amy L / Fretwell, Kenneth R / Fructuoso, Lorena Sanchon / Fusai, Giuseppe K / Garcia, Miguel Hernandez / Garcia-Ureña, Miguel Angel / Gill, Charn K / Gisbertz, Suzanne S / Del Giudice, Roberto / Giuffrida, Maria Carmela / Di Giuseppe, Matteo / Gómez, María Fanjul / Griffiths, Ewen A / Guariglia, Claudio A / Hainsworth, Alison J / Hall, Bria J / Hall, James RW / Hammond, John S / Haqqani, Maha H / Harrison, Ewen M / Hazelton, Joshua P / van Heinsbergen, Maarten / Hill, Arnold DK / Hing, Caroline B / Hirji, Sameer A / Ho, Michael WS / Holbrook, Charlotte M / Holme, Thomas J / Hopkins, James C / Hopkinson, David N / Hossain, Fahad S / Hudson, Victoria E / Hughes, Jane L / Hwang, E. Shelley / Ibrahim, Mohamed AH / Isolani, Simone M / Jenkinson, Michael D / Jenny, Hillary E / Jeyaretna, Deva S / Jones, Robert P / Jones, Andrew P / Jonker, Pascal KC / Jönsson, Maria L / Joyce, Doireann P / Kalkwarf, Kyle J / Kamarajah, Sivesh K / El Kassas, Mohamed / Kavanagh, Dara O / Keatley, James M / Khalefa, Mohamed A / Khan, Jim S / Kirmani, Bilal H / Kisiel, Aaron P / Kouris, Spyros Marinos / Kowal, Mikolaj R / Labib, Peter L / Larkin, John O / Lauscher, Johannes C / Leclercq, Wouter KG / Ledesma, Frances SJ / Leite-Moreira, André M / Leung, Elaine YL / Lewis, Sophia E / Lima, Maria João / Lin, Daniel J / Liu, Helen H / Lowery, Aoife J / Lozano, Saida Martel / Luney, Catriona R / Maia, Mariana Magalhães / Mariani, Nicolò M / Marino, Marco V / Marra, Angelo A / Marsh, Christopher L / Martin, Robert CG / McCluney, Simon J / McIntyre, Robert C / Mckay, Siobhan C / McKevitt, Kevin L / Meagher, Ashley D / Mehdi, Mohammad Q / Mehigan, Brian J / Gonzalez-De Miguel, Melania / De Miguel-Ardevines, Maria-Carmen / Mills, Sarah J / Mohan, Helen M / Moir, John AG / Monson, John RT / Monteiro, Joana M / Montella, Maria T / Montesinos, Cristina Soto / Morgom, Marwa M / Moura, Francisco S / Muguerza, Jose M / Murphy, Suzanne H / De Nardi, Paola / Naumann, David N / Neary, Paul C / Neely, David TA / Ng-Kamstra, Joshua S / Ngu, Albert WT / Nguyen, Truong A / Nita, George E / Nunes, Quentin M / Nygaard, Rachel M / O'Meara, Lindsay B / O'Neill, John R / Okafor, Barbara U / Olson, Steven A / Oo, Aung Y / Ormazabal, Pablo Collera / Osorio, Alexander L / Pachl, Max J / Parry, James T / Patel, Panna K / Pérez-Sánchez, Luis E / Pevidal, Ana Nogues / Pezzuto, Anna P / Philp, Matthew M / Pinkney, Thomas D / Pollok, Joerg M / Povey, Meical G / Poza, Alfredo Alonso / Rajgor, Amarkumar D / Rao, Jagan N / Raptis, Dimitri A / Rice, Henry E / Ridgway, Paul F / Rivas, Ana Munoz / Rodriguez-Sanjuan, Juan C / Rogers, Luke J / Da Roit, Anna / Rollett, Rebecca A / Romera, Jose L / Rooney, Siobhan M / Roxo, Vanessa I / Le Roy, Bertrand / Rubio, Eduardo E / Ruiz, Carolina Castro / Ruiz, Manuel Losada / Ryan, Éanna J / Saad, Abdel Rahman / Saeed, Samerah A / Salama, Hiba A / Salamah, Abdulrauf A / Sampietro, Gianluca M / Sarma, Diwakar R / Schaffer, Kathryn B / Schnitzbauer, Andreas A / Scurrah, Rachel J / Serevina, Olivia L / Serralheiro, Pedro A / Sewards, Joseph M / Shackcloth, Michael J / Shaw, Abigail V / Sheel, Andrea RG / Sica, Giuseppe S / De Simone, Veronica / Singh, Aminder A / Singh, Rabindra P / Skelly, Brendan L / Smith, Henry G / Sohail, Amir H / Spalding, Duncan R / Springford, Laurie R / Ssentongo, Anna E / Steinkamp, Pieter J / Stevens, Kent A / Stewart, Grant D / Stylianides, Nicholas A / Sullivan, Tom BB / Taher, Ahmed SA / Tamimy, Muhammad S / Tang, Alethea M / Tebala, Giovanni D / Tejero-Pintor, Francisco J / Thaha, Mohamed A / Thomas, Amy J / De Toma, Giorgio / La Torre, Filippo / Torres, Antonio J / Townshend, David N / Trout, Isobel M / Tucker, Sarah C / Ubhi, Harmony K / Vega, Viviana A / Velmahos, George C / Velopulos, Catherine G / Viswanath, Yirupaiahgari KS / Vivas, Alfredo A / Wade, Ryckie G / Wadley, Martin S / Wall, Joshua JS / Walters, Andrew M / Warren, Oliver J / Weerasinghe, Chamindri K / Wilkin, Richard JW / Williams, Katherine J / Winter, Stuart C / Wormald, Justin CR / Wright, Franklin L / Xyda, Souzana E / Young, Alastair L / Youssef, Mina MG / Yousuf, Farhat B / El Youzouri, Hanan / Zappa, Marco A / Abate, Emmanuele / Abdalaziz, Hossam / Abdelkarim, Mostafa / Abdou, Hossam / Aboelkassem-Ibrahim, Ahmad / Abuown, Ala / Acebes-Garcia, Fernando / Acharya, Metesh / Adamina, Michel / Addae-Boateng, Emmanuel / Aftab, Raiyyan / Agarwal, Arnav / Aguilar, José / Ahmed, Yousra / Aitken, Emma / Al-Azzawi, Marwa / Al-Embideen, Somya / Al-Masri, Mahmoud / Al-Najjar, Hani / Al-Sukaini, Ahmad / Alam, Ruhina / Alderson, Derek / Aliyeva, Zumrud / Aljanadi, Firas / Almasri, Murad / Alonso-Ortuño, Paula / Altintoprak, Fatih / Amira, Gamal / Amjad, Rabbia / Anania, Gabriele / Andabaka, Tatjana / Angelou, Dimitrios / Annamalai, Seethalakshmi / Annessi, Valerio / Anthoney, James / Anwar, Sibtain / Anwer, Mariyah / Aragon-Chamizo, Juan / Ardito, Antonella / Arigoni, Michele / Armao, Teodora / Arminio, Armando / Armstrong, Lara / Arnaud, Alexis / Asaad, Peter / Ashcroft, James / Ashmore, Christopher / Asqalan, Ahmad / Asti, Emanuele / Aubry, Emmanuelle / Aytac, Erman / Ayuso-Herrera, Esther / Baeza, Melody / Bailon-Cuadrado, Martin / Bakmaz, Bernarda / Baldi, Caterina / Baldini, Edoardo / Baldo, Stefano / Ballabio, Michele / Baloyiannis, Ioannis / Baltazar, Gerard / Bàmbina, Fabrizio / Bandiera, Alessandro / Barlow, Emma / Barmasse, Roberto / Barmpagianni, Christina / Baronio, Gianluca / Barra, Fabio / Bartsch, Anne-Marie / Basgaran, Amedra / Basha, Amr / Bashkirova, Varvara / Bastazza, Marco / Baumber, Rachel / Belcher, Elizabeth / Belvedere, Angela / Benítez-Linero, Inmaculada / Bergeat, Damien / Bernasconi, Matteo / Bhalla, Ashish / Bhutiani, Neal / Bianco, Federica / Bisagni, Pietro / Blake, Iain / Blanco-Colino, Ruth / Blazquez-Martin, Alma / Boal, Matthew / Bonavina, Luigi / Bonavina, Giulia / Bond-Smith, Giles / Booth, Karen / Borges, Filipe / Borghi, Felice / Bouchagier, Konstantinos / Bourke, Grainne / Boyle, Emily / Brachini, Gioia / Brain, Jessie / Brar, Amanpreet / Breckles, Lisa / Bretagnol, Frédéric / Brixton, Genevieve / Bruzzaniti, Placido / Bueser, Teofila / Burnside, Nathan / Caballero, Albert / Calcerrada-Alises, Enrique / Callahan, Miriam / Camarero, Enrique / Campagnaro, Tommaso / Campanelli, Michela / Candiani, Massimo / Cantalejo-Diaz, Miguel / Cao, Han / Capelli, Patrizio / Capizzi, Vita / Carcano, Giulio / Carissimi, Francesca / Carlini, Massimo / Carlucci, Michele / Carmichael, Heather / Carrasco, Milagros / Carrillo, Mariana / Carvello, Michele / Casati, Massimiliano / Castoro, Carlo / Catalan, Vanesa / Cavaleiro, Salomé / Cellerino, Paola / Centinaio, Giovanna / Cernei, Cristina / Cerro, Cristina / Cervellera, Maurizio / Chakrabortee, Sohini / Chamberlain, Stephanie / Chan, Jeffrey / Chang, Grace / Chaudhry, Dauod / Chebaro, Alexandre / Chen, David / Chetty, Govind / Chia, Zoe / Chiappini, Ambra / Chiarugi, Massimo / Chidambaram, Swathikan / Chiozza, Matteo / Cholewa, Hanna / Chong, Clara / Choolani-Bhojwani, Ekta / Christoforidis, Dimitri / Chui, Karen / Chung, Choyin / Cirillo, Bruno / Citterio, Davide / Clermidi, Pauline / Coccolini, Federico / Colletti, Gaia / Compagnoni, Bruno / Concepción-Martín, Vanesa / Confalonieri, Marco / Connolly, Hannah / Conso, Christel / Conti, Luigi / Cooper, Zara / Cordera, Fernando / Corral, Javier / Costa, Marta / Costanzi, Andrea / Cotsoglou, Christian / Cozza, Valerio / Cuming, Tamzin / Curtis, Miles / Cuschieri, Joseph / D'Agruma, Michele / D'Andrea, Giancarlo / Daliya, Prita / Dare, Oliver / Darko, Ebenezer / Day, Andrew / Dehal, Ahmed / Dehart, Dustin / Delgado-Oliver, Eduardo / Denning, Max / Desai, Anant / Desender, Liesbeth / Dester, Sara / Díaz-García, Alberto / Diaz-Peña, Patricia / Dousset, Bertrand / Doussot, Alexandre / Duchateau, Nicolas / Duff, Sarah / Dunning, Joel / Duque-Mallen, Victoria / Dziakova, Jana / Egan, Bridget / Egan, Richard / El-Ali, Abess / Elfeki, Hossam / Elhadi, Muhammed / Eljareh, Mohammed / Elkady, Ramy / Elkhafeefi, Fatimah / Elmore, Ugo / Elmoslemany, Tarek / Emmerson, Oliver / Enemosah, Ibrahim / English, Camilla / English, William / Escartin, Jorge / Estaire-Gomez, Mercedes / Evans, Luke / Evans, Jessica / Exley, Rebecca / Fabbri, Nicoló / Falco, Giuseppe / Familiari, Pietro / Fancellu, Alessandro / Farik, Shebani / Farrell, Tony / Fehervari, Matyas / Fell, Adam / Fernandez-Camuñas, Angel / Fernández-Marín, Reyes / Fernández-Martínez, María / Ferrara, Francesco / Ferrari, Guglielmo / Ferrero, Simone / Findlay, Laura / Fiore, Marco / Fiori, Enrico / Flatman, Michael / Flindall, Ian / Flor, Blas / Fontana, Tommaso / Ford, Samuel / Ford, David / Forlani, Stefano / Francone, Elisa / Frattaruolo, Colomba / Frio, Federico / Gagliano, Annalisa / Gagliardi, Filippo / Gahunia, Sukhpreet / Gaino, Francesca / Gala, Tanzeela / Galfrascoli, Elisa / Galimberti, Luca / Gallagher, Phoebe / Galleano, Raffaele / Galván-Pérez, Armando / Gammeri, Emanuele / Ganau, Mario / Garcés-García, Raúl / Garulli, Gianluca / Gascon-Ferrer, Isabel / Gattolin, Andrea / Gaujoux, Sebastien / Gentilli, Sergio / Georgiades, Fanourios / Ghanbari, Amir / Ghosh, Dhruv / Giacometti, Marco / Giblin, Anna-Victoria / Gilbert, Catherine / Giménez, Clara / Giorgakis, Emmanouil / Gipponi, Manuel / Glen, Paul / Goatly, Giles / Gobatti, Davide / Godbole, Chintamani / Gohil, Kajal / Gómez, Marcos / Gomez-Rosado, Juan-Carlos / Gonullu, Emre / Gonzalez-Gonzalez, Enrique / Gordini, Luca / Gracia, Isabel / Gracia-Roche, Carlos / Granieri, Stefano / Green, Susanna / Grivon, Manuela / Grove, Thomas / Guaglio, Marcello / Guaitoli, Eleonora / Guglielmi, Alfredo / Guha, Soumya / Gustavino, Claudio / Habeeb, Amir / Hagger, Robert / Hakmi, Hazim / Halkias, Constantine / Hall, Claire / Hampton, Matthew / Handa, Siddhartha / Hansen, Laura / Haq, Iram / Harky, Amer / Harries, Rhiannon / Harrison, Joseph / Hasan, Raashad / Hawari, Mohammad / Hawkin, Paul / Hebblethwaite, Bethany / Henriques, Susana / Heritage, Emily / Hernandez-Juara, Pilar / Herrero-Lopez, Maria / Hervieux, Erik / Heyd, Bruno / Higgs, Simon / Hitchman, Louise / Ho, Beatrice / Hogan, Aisling / Hölzle, Frank / Hossain, Tanvir / Hurt, Libor / Hutchinson, Peter / Iacob, Giulio / Iannone, Immacolata / Ibrahim, Sherif / Iovino, Domenico / Isik, Arda / Jafarova, Sevda / Jamil, Tahir / Jayaraju, Ullas / Jenner, Edward / Jimenez-Higuera, Elisa / Jimeno, Jaime / Jones, Mark / Judkins, Nicholas / Kalavrezos, Nicholas / Kalidindi, Venugopala / Kalkat, Maninder / Kamal, Mona / Kamphues, Carsten / Kang, Chong / Kara, Yasin / Karam, Edward / Karim, Ahmed / Kashora, Florence / Kearney, David / Khajuria, Apoorva / Khan, Umul / Khan, Azam / Khatri, Chetan / Kinnaman, Gabriel / Kinross, James / Kler, Aaron / Klimopoulos, Serafeim / Kocataş, Ali / Kolias, Angelos / Königsrainer, Alfred / Konsten, Joop / Kontovounisios, Christos / Kourdouli, Amar / Krishnan, Emily / Kristinsson, Sverrir / Kruijff, Schelto / Kudsk-Iversen, Søren / Kufeji, Dorothy / Kugler, Nadav / Kulkarni, Rugved / Kurihara, Hayato / Laface, Letizia / Lakkis, Zaher / Lami, Mariam / Landaluce-Olavarria, Aitor / Lapolla, Pierfrancesco / Lawani, Ismail / Lawday, Samuel / Lázaro, André / Lecolle, Katia / Leventoglu, Sezai / Li, Zoe / Liew, Ignatius / Lisi, Giorgio / Lizzi, Vincenzo / Lo, Terence / Lomiento, Daniele / Longhi, Marco / Lostis, Emilie / Lostoridis, Eftychios / Loubani, Mahmoud / Lowy-Benoliel, Alejandro / Lucianetti, Alessandro / Luke, Louis / Lunevicius, Raimundas / Luraghi, Marco / Lye, George / Mabrouk, Islam / Macchi, Alberto / MacDonald, Luisa / Machairas, Nikolaos / Madonini, Marco / Magowan, Drew / Maisonneuve, Emeline / Majkowska, Agata / Majkowski, Lawrence / Mak, Jason / Malabarba, Stefano / Malerba, Michele / Mannan, Syed / Manson, Joanna / Mansuri, Ahmer / Mantoglu, Baris / Manu, Nichola / Maqsood, Afnan / Marano, Alessandra / Marchbank, Adrian / Marcos-Santos, Pablo / Marrano, Enrico / Martin, Janet / Martin, Emmeline / Martin, Guy / Martin-Albo, Lorena / Martín-Román, Lorena / Martinelli, Fabio / Martínez-dePaz, Fernando / Martinez-German, Antonio / Martinez-Pinedo, Carlos / Martins, Ricardo / Marwan, Hisham / Marzi, Federica / Mathieu, Pierre / Matute-Najarro, Maria-Soledad / Maw, Andrew / Mazingi, Dennis / Mazzaferro, Vincenzo / McCanny, Andrew / McKenzie, Katherine / McLarty, Nicola / McPherson, Iain / Medina, Esther / Mediratta, Saniya / Medone, Marzia / Mehra, Gautam / Mele, Simone / Melero-Cortés, Lidia / Mendoza-Moreno, Fernando / Meneghini, Simona / Mercante, Giuseppe / Merdrignac, Aude / Merola, Stephen / Metallidis, Symeon / Michel, Martin / Migliore, Marco / Mihanovic, Jakov / Miller, Douglas / Mingoli, Andrea / Minto, Gary / Mirabella, Antonello / Misra, Nikhil / Mitrasinovic, Stefan / Miu, Victor / Moawad, Nader / Mochet, Sylvie / Modabber, Ali / Mohammad, Adam / Mohan, Midhun / Moliner-Sánchez, Carmen / Mongelli, Francesco / Monteleone, Michela / Montuori, Mauro / Moore, Rachel / Mora-Guzmán, Ismael / Morales, Xavier / Morales, Dieter / Morelli, Luca / Morelli, Lucia / Morgan, Richard / Morris, Chris / Mortini, Pietro / Mosca, Angelo / Motter, Dema / Moug, Susan / Mukherjee, Samrat / Najdy, Manhal / Nakas, Apostolos / Namazov, Ilgar / Naredla, Pradyumna / Nasef, Emmhamed / Nassa, Heeam / Nath, Rahul / Navarro-Sánchez, Antonio / Nazarian, Scarlet / Negri, Giampiero / Nehra, Deepika / Neil-Dwyer, Jason / Neri, Jacopo / Newton, Katy / Nikaj, Herald / Niquen, Milagros / Nobile, Sara / Nogueiro, Jorge / Ntirenganya, Faustin / Nugent, Michael / Núñez, Jordi / Ocaña, Juan / Okechukwu, Valentine / Oliva-Mompean, Fernando / Oliveira, Ana / Ollat, Didier / Onos, Lavinia / Osagie-Clouard, Liza / Osman, Khabab / Ottolina, Jessica / Ourieff, Jared / Outani, Oumaima / Oyewole, Bankole / Ozben, Volkan / Pacheco-Sanchez, David / Padilla-Valverde, David / Pai, Madhava / Paiella, Salvatore / Paisley, Samuel / Palini, Gianmarco / Palmeri, Matteo / Panahi, Pedram / Parente, Alessandro / Parlanti, Daniele / Parmar, Chetan / Pascual, Angela / Patel, Mahul / Pathak, Abhijit / Patil, Sangram / Pattyn, Piet / Peckham-Cooper, Adam / Pedrazzani, Corrado / Pellino, Gianluca / Peluso, Chiara / Pereira, André / Pereira-Neves, António / Perez-Diaz, Md / Pérez-González, Marta

    an international cohort study

    2020  

    Keywords covid19
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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